scholarly journals Pneumatosis Coli Mimicking Colorectal Cancer

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Teresa Jacob ◽  
Mohammad Paracha ◽  
Marta Penna ◽  
Dhili Arul ◽  
Jonathan Wilson
Keyword(s):  
Colorectal Cancer ◽  
Surgical Management ◽  
Incidental Finding ◽  
Rare Condition ◽  
Resected Specimen ◽  
Pneumatosis Coli ◽  
Benign Condition ◽  
Asymptomatic Patients ◽  
Successful Recovery ◽  
Emergency Surgical Intervention

Pneumatosis coli (PC) is a rare condition of the gastrointestinal tract involving extraluminal gas confined within the bowel wall. We report the case of a 40-year-old gentleman presenting clinically and endoscopically with suspected colorectal cancer. In light of the patient’s red flag symptoms, and carpet of polyps seen endoscopically, surgical management by an anterior resection was performed with the patient making a successful recovery. Histological analysis of the resected specimen confirmed pneumatosis coli with no evidence of colonic neoplasia. Although PC can be an incidental finding in asymptomatic patients and considered a benign condition, it can also present as a life-threatening emergency with bowel necrosis and obstruction requiring emergency surgical intervention. Also, when PC mimics malignancy, surgical management is the most appropriate step to ensure that the diagnosis of cancer is not missed.

Incidental Finding of Colorectal Cancer in Screening Colonoscopy and Its Cost Effectiveness

2009 ◽  
Vol 75 (8) ◽  
pp. 699-704 ◽  
Author(s):  
Chichi Berhane ◽  
David Denning
Keyword(s):  
Colorectal Cancer ◽  
Cost Effectiveness ◽  
Villous Adenoma ◽  
Colorectal Neoplasm ◽  
Incidental Finding ◽  
Screening Colonoscopy ◽  
Tubular Adenoma ◽  
Hyperplastic Polyps ◽  
Asymptomatic Patients ◽  
Involvement Rate

The objective of this study is to measure the risk of colorectal cancer and adenoma with screening colonoscopy and its cost effectiveness. We reviewed the procedure and pathology results of approximately 11,000 asymptomatic patients age 50 to 90 that underwent screening colonoscopy Among those 11,808 screening colonoscopies performed, advance neoplasm (adenocarcinoma) was detected in 272 (2.3%) patients; age 50 to 90, with mean age of 64-years-old. Fourteen per cent had hyperplastic polyps, 15 per cent had tubular adenoma, and 8.6 per cent villous adenoma. Adenoma with high grade dysplasia was found in 6.6 per cent, and 5.5 per cent had nonadenomatous lesions. Sixty-five of 272 (24%) neoplasms were found proximally Forty-five of 207 distal neoplasms were found through sigmoidoscopy, nine of 45 (20%) had proximal involvement. Rate of complication during colonoscopy was 0.06 per cent and no patients died. All patients underwent complete colonoscopy, 99.8 per cent were men. Rate of adenocarcinoma from 2000 to 2006 was (24/470, 29/520, 33/891,37/961,46/2889,49/2977, and 54/3100). Screening colonoscopy can detect advanced colorectal neoplasm in asymptomatic adults. The more screening colonoscopy was preformed the earlier the neoplasm was discovered and with better prognosis. Twenty per cent of the patients with distal neoplasms found on sigmoidoscopy had proximal lesions when complete colonoscopies were performed. These findings warrant refinement of the screening recommendations for colorectal cancer.

Tracheoinnominate fistula: surgical management of an iatrogenic disaster

2006 ◽  
Vol 120 (8) ◽  
pp. 676-680 ◽  
Author(s):  
R W Ridley ◽  
J B Zwischenberger
Keyword(s):  
Operating Room ◽  
Surgical Management ◽  
Surgical Repair ◽  
Surgical Intervention ◽  
Pectoralis Major Muscle ◽  
Muscle Flap ◽  
Rare Condition ◽  
Innominate Artery ◽  
Significant Potential ◽  
High Index Of Suspicion

Tracheoinnominate fistula (TIF) is a rare condition with significant potential for mortality if surgical intervention is not immediate. We present two cases of successfully managed TIF. Both cases involve ligation and resection of the innominate artery at the TIF followed by a pectoralis major muscle flap. In both cases, success was largely due to a high index of suspicion and immediate control of the bleeding with transport to the operating room for surgical repair. The history, aetiology, and pathogenesis of TIF are reviewed, yielding an algorithm for recommended management of TIF.

Appendiceal adenocarcinoma with breast metastases

2021 ◽  
Vol 14 (5) ◽  
pp. e240808
Author(s):  
Timothy Davies ◽  
Tarak Chouari ◽  
Christopher Ray ◽  
Suzanne Elgammal
Keyword(s):  
Colorectal Cancer ◽  
Incidental Finding ◽  
Symptomatic Treatment ◽  
Vermiform Appendix ◽  
Left Breast ◽  
Regional Lymph Nodes ◽  
Appendiceal Adenocarcinoma ◽  
First Case ◽  
Simple Mastectomy ◽  
Malignant Lesions

Malignant lesions of the vermiform appendix make up a rare subset of colorectal cancer. While colorectal cancer frequently metastasises to the liver, lung, regional lymph nodes and peritoneum, metastasis to the breast is extremely rare. Here, we describe the case of an 84-year-old woman who had the incidental finding of appendiceal adenocarcinoma following emergency laparoscopic appendectomy. She declined further operative or adjuvant treatment for her disease. She represented 1 year later with metastatic appendiceal adenocarcinoma disease to her left breast. A simple mastectomy for symptomatic treatment was performed. In this report, we describe the first case of appendiceal adenocarcinoma metastases to the breast. Due to its rarity, there is a paucity of evidence related to the management of this condition. The limited evidence is reviewed and discussed.

Evaluation of Histopathological Heterogeneity After Preoperative Chemotherapy in Patients With Liver Metastases from Colorectal Cancer

2021 ◽  
Author(s):  
Nobuhisa matsuhashi ◽  
Hiroyuki Tomita ◽  
Takazumi Kato ◽  
Yoshinori Iwata ◽  
Satoshi Matsui ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastasis ◽  
Liver Metastases ◽  
Surgical Oncology ◽  
Resected Specimen ◽  
Histopathological Changes ◽  
School Of Medicine ◽  
Response To Chemotherapy ◽  
Grade 3 ◽  
The Right

Abstract Background: Patients with liver metastases from colorectal cancer (CRLMs) frequently receive chemotherapy prior to liver resection. Histopathological assessment of the resected specimen can evaluate the response to chemotherapy. This study analyzed the correlation between histopathological changes in the primary site and liver metastases. Patients and Methods: This study comprised 45 patients with resectable CRLMs at the Surgical Oncology Department of Gifu University School of Medicine from January 2006 to August 2015. Results: The study included 24 men and 21 women. The primary colonic tumor was located in the right side in 13 (28.9%) patients and the left side in 32 (71.9%) patients. We evaluated patients with metastatic colorectal cancer (31/45) after excluding those in whom histopathological heterogeneity between the primary and liver metastasis changed to grade 3 after chemotherapy. We compared the group which underwent hepatectomy after chemotherapy (n=25) with that underwent hepatectomy alone (n=6). In 16 (53.3%) out of 25 patients, histopathological heterogeneity of the liver metastasis was lost (p=0.04). Conclusion: Chemotherapy appears to change histopathological heterogeneity.Our study suggests that the change of intratumoral heterogeneity reflect by the response of chemotherapy.

Badania przesiewowe w profilaktyce raka jelita grubego

2018 ◽  
Vol 21 (3) ◽  
Author(s):  
Marta Musińska ◽  
Marta Minkiewicz ◽  
Justyna Wasielica-Berger ◽  
Krystian Kidrycki ◽  
Krzysztof Kurek
Keyword(s):  
Colorectal Cancer ◽  
Screening Program ◽  
Single Step ◽  
Preventive Action ◽  
Asymptomatic Patients ◽  
Oncological Diseases ◽  
History Of ◽  
Genetic And Environmental Factors ◽  
Therapeutic Tools

Colorectal cancer is the second most frequently diagnosed cancer in Poland as well as in the world. In addition, this cancer is the second cause of death among oncological diseases. Genetic and environmental factors with a documented impact on the development and progression of colorectal cancer have been thoroughly investigated. Every case of colorectal cancer begins with the stage of a nonmalignant polyp, whose progression to invasive malignant tumor lasts about 10 years. This period is long enough to implement appropriate preventive action that allow early detection and treatment of pre-cancerous lesions. Colorectal cancer screening is the process of detecting polypoid lesions in asymptomatic patients with no history of cancers. Colonoscopy has the benefit of diagnostic and therapeutic tools, which allows to detect and remove of premalignant polyps in a single step approach. The aim of this work is to present the role of a screening program in the prevention of colorectal cancer.

scholarly journals Surgical management and outcomes of colorectal cancer liver metastases

2010 ◽  
Vol 97 (7) ◽  
pp. 1110-1118 ◽  
Author(s):  
E. J. A. Morris ◽  
D. Forman ◽  
J. D. Thomas ◽  
P. Quirke ◽  
E. F. Taylor ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastases ◽  
Surgical Management ◽  
Colorectal Cancer Liver Metastases

scholarly journals Non-invasive colorectal cancer screening

2016 ◽  
Vol 85 (2) ◽  
pp. 29-31
Author(s):  
Melissa Holdren ◽  
Brittany Deller ◽  
Kevin Braden
Keyword(s):  
Colorectal Cancer ◽  
Developmental Process ◽  
Population Based ◽  
Adenomatous Polyps ◽  
Morbidity And Mortality ◽  
Screening Tests ◽  
Average Risk ◽  
Screening Programs ◽  
Asymptomatic Patients ◽  
Advanced Adenomas

Colorectal cancer (CRC) is a major cause of morbidity and mortality throughout the world and is the second most common cause of Canadian cancer-related deaths in men and the third most common in women. Most CRC appears to arise from the gradual development and advancement of colonic adenomatous polyps to cancerous tissue. This developmental process of CRC is the rationale for screening programs which aim to reduce CRC-related morbidity and mortality by early detection and removal of adenomatous polyps, specifically advanced adenomas. Although both the gFOBT and FIT function to detect occult bleeding in asymptomatic patients at average risk for CRC development, the mechanisms of these screening tests are distinct. gFOBT works by detecting the peroxidase activity of heme whereas FIT selectively detects human hemoglobin. The sensitivity in detecting CRC is higher for the FIT, with sensitivity of 0.79 compared to gFOBT with sensitivity of 0.36, they have similar specificities of 0.94 and 0.96, respectively. Currently, both the gFOBT and FIT are strongly recommended across Canada, with all provinces using the FIT, apart from Ontario and Manitoba which currently use the gFOBT to screen asymptomatic patients for CRC. A newer test, the sDNA test, identifies mutations in DNA that are shed by both adenomatous polyps and CRC cells. The sDNA test is more sensitive (0.92 95% CI 0.83-0.98) than both the gFOBT and FIT, however, is less specific and more expensive. Further data surrounding the sDNA test will be required prior to its implementation and recommendation for population based CRC screening in Canada. 

scholarly journals An Incidental Finding of Situs Ambiguus with Polysplenia in an Asymptomatic 70-Year-Old Male

2021 ◽  
pp. 1-3
Author(s):  
Christopher Ambrogi ◽  
◽  
Madina Ndoye ◽  
Keyword(s):  
Prostate Cancer ◽  
Urinary Retention ◽  
Acute Urinary Retention ◽  
Incidental Finding ◽  
Anatomical Variation ◽  
Rare Condition ◽  
Situs Ambiguus ◽  
Abdominal Organs ◽  
The Right ◽  
Thoracic And Abdominal

The term “Situs ambiguus” describes the configuration when some, but not all thoracic and abdominal organs are abnormally positioned. It is commonly associated with polysplenia, or multiple spleens. 50-100% of situs ambiguus with polysplenia have associated cardiac malformations [1]. We present a 70 year old male who came to our hospital for complete, acute, urinary retention, and was found to have invasive prostate cancer. Incidentally, the liver was positioned on the left side, and the spleen was located on the right side. There were multiple perisplenic nodular formations with peripheral calcifications that had enhancement kinetics similar to those of the spleen, suggesting polysplenia. In low thoracic cuts, the tip of the heart was clearly on the left side. The presence of situs ambiguus with polysplenia in the absence of cardiac abnormalities makes this case a unique presentation of an already rare condition. Clinicians should regularly consider the possibilities of anatomical variation in their medical and surgical practices.

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