scholarly journals Low Concordance with the DASH Plan Is Associated with Higher Cardiovascular Risk in Treated Hypertensive Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
M. A. Casanova ◽  
F. Medeiros ◽  
W. Oigman ◽  
M. F. Neves
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Logistic Regression ◽  
Cardiovascular Risk ◽  
Food Groups ◽  
Age And Gender ◽  
Food Frequency ◽  
Hypertensive Patients ◽  
Vascular Age ◽  
And Gender

This study aimed at analyzing the alimentary habits of treated hypertensive patients identifying the degree of concordance with Dietary Approaches to Stop Hypertension (DASH) plan. Anthropometry and blood pressure (BP) were evaluated, and the 10-year risk for general cardiovascular disease was estimated and used to calculate vascular age. A DASH concordance score was obtained using food frequency questionnaire and the cut-off points were established for eight food groups. Subjects were divided into two groups according to the median of DASH concordance score: lower concordance (LC group < 4.5 points, n=33) and higher concordance (HC group ≥ 4.5 points, n=47). LC group was associated with higher BP, vascular age, and cardiovascular risk. DASH concordance score was positively correlated with intake of fiber, calcium, potassium, and magnesium (P<0.001) and negatively correlated with BP, cardiovascular risk, and vascular age (P<0.05). After logistic regression adjusted for age and gender, only cardiovascular risk (β=-0.154, P=0.031) was independently associated with DASH concordance score. Hypertensive patients with dietary patterns less concordant with the DASH plan had higher BP levels and increased cardiovascular risk, indicating the relevance of management in the treatment of these patients.

scholarly journals Use of Global Risk Score for Cardiovascular Evaluation of Rural Workers in Southern Brazil

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Marta Regina Cezar-Vaz ◽  
Clarice Alves Bonow ◽  
Marlise Capa Verde Almeida de Mello ◽  
Daiani Modernel Xavier ◽  
Jordana Cezar Vaz ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Risk Score ◽  
Southern Brazil ◽  
Global Risk ◽  
Rural Workers ◽  
Arterial Blood ◽  
And Gender ◽  
Cardiovascular Evaluation

The objectives of the present study were to classify the cardiovascular evaluation of rural workers through the Global Risk Score and analyze the intensity of the relationship between the classification and the variables of the score. A descriptive study was developed with 38 rural workers from the extreme southern Brazil. Data collection was performed through an interview and verification of anthropometric measurements and arterial blood pressure. Data were analyzed descriptively and inferentially using the Spearman correlation test. The overall 10-year cardiovascular risk classification using the Framingham global score showed a predominance of low risk (n=22; 57.9%); however, 11 rural workers (28.9%) had a high cardiovascular risk. Spearman’s correlation analysis showed significance between the Global Risk Score and gender (rho = 0.623, p≤0.001), age (rho = 0.783, p≤0.001), systolic blood pressure (rho = 0.545, p≤0.001), and smoking (rho = 0.483, p=0.002). These results show that rural workers need attention with regard to components that may put them at risk for cardiovascular disease. This study may help in the early diagnosis and more effective actions on the risk factors for cardiovascular disease.

scholarly journals Cardiovascular risk factors in first-degree relatives of patients with hypertension*

2011 ◽  
pp. 17-25
Author(s):  
Martha Lucía Gallego ◽  
Nelsy Loango ◽  
Martha Lucía Gallego
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Absolute Risk ◽  
Male And Female ◽  
Hypertensive Patients ◽  
Low Hdl ◽  
Males And Females

Objective: To evaluate the prevalence of cardiovascular risk factors (CRF) and absolute risk (AR) among first-degree consanguinity relatives of Colombian patients with hypertension. Methods: The study comprised 227 relatives (siblings and children of both sexes, between 12 and 40 years of age) and 204 hypertensive patients 34-84 years old from Quindío, Colombia. Lipid profile, glycemia, smoking, body mass index, and blood pressure were analyzed, and the AR of cardiovascular disease (CVD) to 10 years was estimated. Relatives were divided into two groups: GF1 relatives <18 years, GF2 relatives >18 years. Results: three or more CRF were found in the three groups. The prevalence for smoking was 20.1%, 9.1%, and 15.9% in patients, GF1, and GF2, respectively. Hypercholesterolemia was 42.2%, 15.2%, and 18.6% in patients, GF1, and GF2, respectively. The prevalence of low HDL-c levels was 50.5%, 44.9%, and 63.6% in relatives, GF1, and GF2, respectively. Obesity was present alone in patients, (32.4%) and GF2 (10.8%). The AR was 19.6 and 6.4 in male and female patients, respectively; 0.31 and 0 in GF1 females and males, respectively, and in GF2 it was 1.5 and 0.15 in males and females, respectively. Conclusions: Patients and relatives had more than three CRFs. HDL-c was low in all three groups. The AR was high in the young relatives. Programs are needed for weight, smoking, sedentary and dyslipidemia control to prevent or delay the development of CVD in relatives.

Abstract P054: Influence of Psychosocial factors in the Blood Pressure Control and Adherence to Drug Therapy in Hypertensive patients

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Daniela Sandoval ◽  
Miguel Bravo ◽  
Tomás Romero ◽  
Elard Koch ◽  
Sebastián Gatica ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Family Income ◽  
Pressure Control ◽  
Patient Relationship ◽  
Physician Patient Relationship ◽  
Age And Gender ◽  
Family Function ◽  
Hypertensive Patients ◽  
And Gender ◽  
Physician Patient

Background: Multiple factors have been implicated in the lack of adherence to drug therapy in hypertensive patients. Objectives: In this study we addressed the impact of psychosocial factors over adherence in a hypertensive cohort followed through a Government sponsored primary care program (PCS) in Santiago, Chile. Method: Cross-sectional study, from a cohort of 738 hypertensive patients followed through the PCS; a sub sample of 89 patients who finished the first stage of recruitment was analyzed, and their results weighted by age and gender. Surveys of family function (APGAR), social support (MOS), health self-perception and physician-patient relationship were carried out. Total family income and education level were evaluated. Therapeutic adherence was determined using the Morisky test. The analyisis was performed by logistic regression estimating age and sex adjusted odds ratio. Results: The mean age of the sample was 54.3±7.6 years, being higher in men (56.2±6.4 years vs. 52.7±8.2 years). Satisfactory blood pressure control (BP<140/90) for the group was found in 66.2% (488 of 738) (68.7% (231 of 336) in men vs. 64.1% (258 of 402) in women; p<0.05). Adherence to treatment for the group was 28.1% (207 of 738) women show higher adherence than men (39.8% (160 of 402) vs. 14.9% (50 of 336); p<0.05). The odd ratios of factors influencing therapeutic adherence are shown in Table 1. Conclusion: In addition to family income and educational level, physician-patient relationship and family function are factors that showed a significant influence on the adherence to anti-hypertensive treatment. The BP control (66.2%) observed in this cohort appeared only partially explained by adherence to therapy (28.1%). A greater observance of dietary and other unmeasured life style changes as a result of the PCS program may have been at play to explain these findings. These aspects will be explored during the follow up. Table 1. Odds -Ratios (OR) of factors influencing adherence to drug Rx in hypertensive patients Adheres to treatment Does not adhere to treatment Raw OR (IC 95%) Adjusted by age and gender OR (IC 95%) Blood pressure (>140/90 mmHg) 29.6% (61 of 208) 36.4% (193 of 530) 1.36 (0.94 - 1.97) 1.48 (1.00 - 2.19) Low education (< 8 years) 30.2% (63 of 208) 47.6% (252 of 530) 2.16 (1.46 . 3.02) 2.28 (1.54 - 3.38) Low family income (Less than 1 minimal salary) 25.4% (53 of 208) 29.6% (157 of 530) 1.22 (0.83 - 1.76) 2.19 (1.42 - 3.37) Health self-perception (Good and very good) 3.3% (7 of 208) 14.3% (76 of 530) 5.43 (1.96 - 15.04) 3.85 (1.36 - 10.93) Scarce social support (MOS < 57 global pts) 44.2% (92 of 208) 36.8% (195 of 530) 0.73 (0.52 - 1.03) 0.84 (0.58 - 1.20) Dysfunctional family (APGAR < 7 pts) 21.6% (45 of 208) 31.0% (164 of 530) 1.65 (1.09 - 2.47) 2.47 (1.59 - 3.81) Inadequate physician-patient relationship 28.4% (59 of 208) 47.3% (251 of 530) 2.26 (0.73 - 6.98) 4.36 (0.81 - 23.39)

Metabolic determinants of proximal aortic stiffness among healthy people with abdominal obesity

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
G Tsaban ◽  
A Yaskolka-Meir ◽  
E Rinott ◽  
H Zelicha ◽  
A Kaplan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Abdominal Obesity ◽  
Aortic Stiffness ◽  
Healthy Population ◽  
Cumulative Number ◽  
Age And Gender ◽  
And Gender ◽  
Healthy Participants

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): (1) the Deutsche Forschungsgemeinschaft; (2) Israel Ministry of Health Background Increased proximal aortic stiffness (PAS) is directly associated with cardiovascular risk. Likewise, metabolic syndrome (MS) and abdominal obesity are associated with cardiovascular risk. The direct association between MS determinants and PAS among a healthy population with abdominal obesity remains to be examined. Purpose To examine the association between MS determinants and PAS among healthy participants with abdominal obesity. Methods We utilized the cross-sectional baseline data of the DIRECT-PLUS study (clinicaltrials.gov NCT03020186), where we recruited healthy participants with abdominal obesity/dyslipidemia. Along with anthropometric measurements and blood tests, all participants underwent magnetic-resonance-imaging from which PAS we assessed by calculating the aortic arch pulse-wave-velocity (from the ascending to the descending aorta). We defined MS according to the NCEP-ATP-III criteria. Results Of 282 participants who had a valid PAS estimation [mean-age: 51.0, 88.3% male, mean-body-mass-index: 31.2kg/m2, mean-waist circumference (WC): 109.5cm] 171 (60.9%) had MS. PAS was mainly associated with age (r = 0.735, p &lt; 0.001). PAS was associated with an increased 10-year Framingham Risk Score (β=0.165,p = 0.008 after adjustment for age and gender). Participants with MS had higher PAS than non-MS participants (6.6m/sec vs. 5.4m/sec, p = 0.002 after adjusting for age and gender). PAS increased along with cumulative number of MS criteria (p-of-trend &lt; 0.001). In multivariate models, adjusted for gender, age, and dichotomous-components of the MS, worse PAS remained significantly associated with high-density lipoprotein cholesterol (HDL-c; β=0.-116,p = 0.007) and increased blood-pressure (β=0.165,p &lt; 0.001), but not with fasting-glucose, waist-circumference or plasma-triglycerides (p &gt; 0.05 for all). In models adjusted for age, gender, and continuous determinants of MS, worse PAS remained associated with mean-arterial pressure (β=0.218,p &lt; 0.001) and HDL-c (β=0.-126,p = 0.004). Conclusions Among a healthy population with abdominal obesity, reduced HDL-c levels and increased blood pressure might be the more dominant predictors of poor PAS state, out of the MS components.

Time in blood pressure range for different blood pressure targets and risk of cardiovascular disease: an analysis of a 7-year follow-up registry

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
K Sideris ◽  
A Kasiakogias ◽  
D Konstantinidis ◽  
P Papakonstantinou ◽  
F Tatakis ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Composite Endpoint ◽  
Hypertensive Patients ◽  
Blood Pressure Targets ◽  
History Of ◽  
Optimal Target ◽  
Artery Disease ◽  
Blood Pressure Range

Abstract Objective Recent guideline recommendations have revisited the optimal target blood pressure (BP) for hypertensive patients. The Time in BP Range (TBPR) is an alternative metric for evaluation of long-term achieved BP. We investigated the association of TBPR for different levels of BP control with cardiovascular outcome among treated hypertensives. Design and method This is a retrospective analysis of 1202 treated hypertensive patients (age 59±11 years) without a history of cardiovascular disease followed for a mean period of 7±3 years. We calculated the TBPR [(No of Visits in BP range/ Total No of Visits) x 100%] for office systolic BP targets of 130–139mmHg, 120–129mmHg and &lt;120mmHg and examined the associated cardiovascular risk. The outcome studied was the composite of stroke and coronary artery disease. Time spent in systolic BP≥140mmHg served as the reference. Results In the entire population, mean TBPR for systolic BP 130–139mmHg, 120–129mmH, and &lt;120mmHg were 26%, 19% and 11% respectively. A TBPR of ≥50% for systolic BP 130–139mmHg, 120–129mmHg and &lt;120mmHg was observed in 332 (28%), 226 (19%) and 107 (9%) patients respectively. The composite endpoint occurred in 54 patients (4.5%). Patients with a TBPR for 120–140mmHg of ≥50% presented with a HR: 0.6 (95% CI: 0.34–1.06) for cardiovascular events. The TBPR of ≥50% for systolic BP 130–139mmHg, 120–129mmHg and &lt;120mmHg was associated with HR of 0.48 (95% CI: 0.23–1.01, p=0.05), 0.64 (95% CI: 0.29–1.39, p=0.26) and 0.72 (95% CI: 0.26–2.05) respectively. This pattern was sustained but further attenuated after controlling for standard risk factors. In comparison, a mean BP across visits of 130–139mmHg, 120–129mmHg and &lt;120mmHg was associated with a HR of 0.54 (5% CI: 0.28–1.03), 0.61 (95% CI: 0.29–1.26) and 0.80 (95% CI: 0.24–2.65). Conclusions Among treated hypertensives, a time in BP of 130–140mmHg of more than 50% is associated with the greatest reduction in cardiovascular risk. The TBPR is a potentially useful measure of BP control for evaluation of risk reduction in hypertensive patients. Funding Acknowledgement Type of funding source: None

scholarly journals Blood pressure levels and cardiovascular risk according to age in patients with diabetes mellitus: a nationwide population-based cohort study

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Hack-Lyoung Kim ◽  
Hyue Mee Kim ◽  
Chang Hee Kwon ◽  
Jeong-Hun Shin ◽  
Mi-Hyang Jung ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Cardiovascular Events ◽  
Cardiovascular Death ◽  
Population Based ◽  
Hypertensive Patients ◽  
Patients With Diabetes ◽  
History Of

Abstract Background Little is known about age-specific target blood pressure (BP) in hypertensive patients with diabetes mellitus (DM). The aim of this study was to determine the BP level at the lowest cardiovascular risk of hypertensive patients with DM according to age. Methods Using the Korean National Health Insurance Service database, we analyzed patients without cardiovascular disease diagnosed with both hypertension and DM from January 2002 to December 2011. Primary end-point was composite cardiovascular events including cardiovascular death, myocardial infarction and stroke. Results Of 241,148 study patients, 35,396 had cardiovascular events during a median follow-up period of 10 years. At the age of < 70 years, the risk of cardiovascular events was lower in patients with BP < 120/70 mmHg than in those with BP 130–139/80–89 mmHg. At the age of ≥ 70, however, there were no significant differences in the risk of cardiovascular events between patients with BP 130–139/80–89 mmHg and BP < 120/70 mmHg. The risk of cardiovascular events was similar between patients with BP 130–139/80–89 mmHg and BP 120–129/70–79 mmHg, and it was significantly higher in those with BP ≥ 140/90 mmHg than in those with BP 130–139/80–89 mmHg at all ages. Conclusions In a cohort of hypertensive patients who had DM but no history of cardiovascular disease, lower BP was associated with lower risk of cardiovascular events especially at the age of < 70. However, low BP < 130–139/80–89 mmHg was not associated with decreased cardiovascular risk, it may be better to keep the BP of 130–139/80–89 mmHg at the age of ≥ 70.

scholarly journals EVA and SUPERNOVA concepts of vascular aging: ongoing research on damaging and protective risk factors

2020 ◽  
Vol 26 (2) ◽  
pp. 133-145
Author(s):  
O. P. Rotar ◽  
K. M. Tolkunova
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Vascular Stiffness ◽  
Vascular Aging ◽  
Age And Gender ◽  
Ongoing Research ◽  
Cardiometabolic Diseases ◽  
Vascular Age ◽  
And Gender ◽  
Biological State

Regarding prevention of cardiometabolic diseases, we often rely on the concepts of risk and disease, rather than the possibility of prevention. The concept of “vascular age” is developed to assess the biological state of arteries and to present cardiovascular risk in years for better understanding by the doctor and patient. Early vascular aging (EVA) syndrome has been studied for more than 10 years to determine the optimal diagnostic criteria and treatment approaches. In 2019, leading experts in the area of vascular stiffness suggested the opposite concept of supernomal vascular aging (SUPERNOVA), in which patients have extremely low vascular stiffness rates for their age and gender. This review discusses new data about factors that accelerate or slow vascular aging.

Impact of age and sex on subclinical coronary atherosclerosis in a healthy asian population

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
M Wong ◽  
J Yap ◽  
KK Yeo
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Coronary Artery ◽  
Coronary Atherosclerosis ◽  
Ldl Cholesterol ◽  
Multivariable Analysis ◽  
Asian Population ◽  
Atherosclerotic Cardiovascular Disease ◽  
Age And Gender ◽  
And Gender

Abstract Funding Acknowledgements Type of funding sources: None. Background and Aims The influence of age and gender on clinical atherosclerotic cardiovascular disease is well reported, but literature remains sparse on whether these extend to the disease in its preclinical stage. We aim to report the prevalence, risk-factors and impact of age and gender on the burden of subclinical coronary atherosclerosis in a healthy Asian population. Methods Healthy subjects aged 30-69 years old, with no history of cardiovascular disease or diabetes were recruited from the general population. Subclinical coronary atherosclerosis was quantified via the Coronary Artery Calcium Score (CACS) with CACS of 0 indicating the absence of calcified plaque, 1 to 10 minimal plaque, 11 to 100 mild plaque, and &gt;100 moderate to severe plaque. Results A total of 663 individuals (mean age 49.4 ± 9.2 years, 44.8% male) were included. The prevalence of any CAC was 29.3% with 9% having CAC &gt; 100.  The prevalence was significantly higher in males than females (43.1 vs 18.0%, p &lt; 0.001). These gender differences became increasingly pronounced with increasing age, especially in those with moderate-severe CAC. Multivariable analysis revealed significant associations between increasing age, male, higher blood pressure, increased glucose levels and higher LDL cholesterol levels with the presence of any CAC. LDL cholesterol was more significantly associated with CAC in females compared to males (Pinteraction = 0.022). Conclusions The prevalence of preclinical atherosclerosis increased with age, and was higher in males than females, with gender-specific differences in associated risk factors. These results will better inform individualised future risk management strategies to prevent the development and progression of coronary artery disease within healthy individuals.

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