scholarly journals The Long Term Effect of Elective Colpoperineoplasty on Sexual Function in the Reproductive Aged Women in Iran

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Safieh Jamali ◽  
Parvin Abedi ◽  
Athar Rasekh ◽  
Razieh Mohammadjafari
Keyword(s):  
Sexual Function ◽  
Prospective Observational Study ◽  
Term Effect ◽  
Reproductive Age ◽  
Repeated Measure ◽  
Long Term Effect ◽  
The Mean ◽  
Reproductive Aged Women ◽  
Vaginal Laxity

Objective. Many women are suffering from sexual dysfunction followed by vaginal laxity in their reproductive age. The aim of this study was to evaluate the long term effect of colpoperineoplasty on sexual function in Iranian reproductive aged women. Methods. This was a prospective observational study in which 79 women with vaginal laxity who were candidate for selective colpoperineoplasty in Jahrom, Iran, were recruited. Data on sexual function was collected via the Female Sexual Function (FSFI) questionnaire preoperatively, six months and 18 months after colpoperineoplasty. The paired t-test, Wilcoxon, Mann-Whitney, and Repeated Measure test were utilized for statistical purposes. Results. Seventy-six women completed the study by 18 months. The mean FSFI score changed from 24.19 ± 3.09 in baseline to 26.92 ± 3.41 after six months (P < 0.001); however dyspareunia and vaginal dryness were increased significantly. After 18 months all areas of sexual function including pain and lubrication improved significantly compared to the 6th month (P < 0.001). Sexual satisfaction was increased significantly six and 18 months after surgery (P < 0.001), and the total score of sexual function increased to 32.61 ± 1.32 after 18 months (P < 0.001). Conclusion. The long term effect of colpoperineoplasty in women who suffer from vaginal laxity is promising. It seems that patient’s dissatisfaction of sexual function can be a basis for colpoperineoplasty.

Long-term effect of natalizumab in patients with RRMS: TYSTEN cohort

2020 ◽  
pp. 135245852093623
Author(s):  
Kévin Bigaut ◽  
Thibaut Fabacher ◽  
Laurent Kremer ◽  
Jean-Claude Ongagna ◽  
Arnaud Kwiatkowski ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Disease Activity ◽  
Predictive Factors ◽  
Term Effect ◽  
Cumulative Probability ◽  
Secondary Progressive ◽  
Long Term Effect ◽  
The Mean ◽  
Poor Outcomes

Background: Data are needed on long-term effect of natalizumab (NTZ) in relapsing-remitting multiple sclerosis (RRMS). Objectives: To evaluate the time of onset of secondary progressive phase in patients with an RRMS treated with NTZ and to investigate predictive factors. Methods: TYSTEN is an observational study. Patients starting NTZ between 2007 and 2012 were included and followed up until October 2018. Relapses, Expanded Disability Status Scale (EDSS) scores, and results of brain magnetic resonance imaging (MRI) were collected each year. Data were used to estimate the cumulative probability of several poor outcomes such as secondary progressive multiple sclerosis (SPMS) conversion, EDSS worsening, EDSS 4.0, and EDSS 6.0. Results: 770 patients were included. The mean follow-up duration was 97 months and the mean time exposure to NTZ was 66 months. At 10 years, the cumulative probability of SPMS was 27.7%. Predictive factors for poor outcomes were a ⩾1-point increase in EDSS score from baseline, new T2 lesion or T1 gadolinium-enhancing lesion, the occurrence of relapse at 1 or 2 years and No Evidence of Disease Activity (NEDA-3; no relapse, no new T2 or T1 gadolinium-enhancing lesions, no progression) was a protective factor. Conclusion: In our cohort of patients treated with NTZ, poor outcomes were infrequent and are driven by disease activity.

OBSERVATIONS ON SUCCESSIVE PRO-OESTROUS LH SURGES IN INDIVIDUAL 4-DAY CYCLING AND POST-PSEUDOPREGNANT RATS

1978 ◽  
Vol 88 (2) ◽  
pp. 274-284 ◽  
Author(s):  
Alberto J. Carrillo ◽  
Charles H. Sawyer
Keyword(s):  
Mechanical Stimulation ◽  
Term Effect ◽  
Oestrous Cycle ◽  
The Other ◽  
Peak Amplitude ◽  
Lh Surge ◽  
Long Term Effect ◽  
The Mean ◽  
Stimulation Of

ABSTRACT The internal variations (i. e. in timing, duration and amplitude) of the LH surge mechanism within individual rats were examined by monitoring from 3 to 7 successive pro-oestrous LH surges in each of 5 regular 4-day cycling rats fitted with chronic intravenous cannulas. On each successive pro-oestrus blood was collected (0.5–0.6 ml hourly from 14.00–21.00) for radioimmunoassay of LH. The surgery of cannulation had no long-term effect on the regularity of the oestrous cycle. Two rats did, however, show briefly irregular cycles, including one with a 9-day period of anoestrus (pseudopregnancy). In three of the five rats successive pro-oestrous plasma LH curves (4 in one and 3 each in the other two) were internally very consistent in timing, shape and amplitude, However, between each 2 of these 3 animals there were distinct differences in the LH secretory patterns, by as much as 2 h in timing of the onset of the surge and its peak amplitude. The first two surges of the other two rats were atypical of their subsequent surges, which were mostly consistent in timing and amplitude. The pro-oestrous LH surge following the 9-day period of anoestrus was advanced by 2 h and elevated to twice the mean peak amplitude of the cyclic LH surges in that rat. Subsequently, post-PSP surges were studied in rats made pseudopregnant by mechanical stimulation of the cervix. In all cases the immediate post-PSP surge occurred earlier in the afternoon and with a greater peak amplitude than the subsequent cyclic LH surge in the same rat.

scholarly journals Long term effect of vaginal delivery and cesarean section on female sexual function in primipara mothers

10.19082/3991 ◽  
2017 ◽  
Vol 9 (3) ◽  
pp. 3991-3996 ◽  
Author(s):  
Fereshteh Ghorat ◽  
Reza Jafarzadeh Esfehani ◽  
Masoumeh Sharifzadeh ◽  
Yaser Tabarraei ◽  
Shima Sadat Aghahosseini
Keyword(s):  
Cesarean Section ◽  
Sexual Function ◽  
Vaginal Delivery ◽  
Term Effect ◽  
Female Sexual Function ◽  
Long Term Effect

scholarly journals Long Term Effect of Mode of Delivery on Sexual Function: A cross-Sectional Study

2021 ◽  
Vol 3 (2) ◽  
pp. 1456-1462
Author(s):  
Samar Hassan Mahmoud Mahmoud ◽  
Alaa eldin Mahmoud Megahed ◽  
Khattab AbdeELhalim Omar Khattab
Keyword(s):  
Sexual Function ◽  
Mode Of Delivery ◽  
Cross Sectional Study ◽  
Term Effect ◽  
Sectional Study ◽  
Cross Sectional ◽  
Long Term Effect

THE LONG-TERM EFFECT OF TRANSECTION OF THE PITUITARY STALK ON THE VOLUME OF THE PITUITARY GLAND OF THE ADULT GOAT

1966 ◽  
Vol 51 (3) ◽  
pp. 377-390 ◽  
Author(s):  
J. Hume Adams ◽  
Peter M. Daniel ◽  
M. L. Prichard
Keyword(s):  
Term Effect ◽  
Pituitary Stalk ◽  
Pars Intermedia ◽  
Pars Distalis ◽  
Long Term Effect ◽  
Severe Reduction ◽  
Pituitary Glands ◽  
The Mean ◽  
Parenchymal Cells

ABSTRACT A study was made of the changes in volume of the pituitary glands of adult female goats surviving for many weeks after pituitary stalk section. The mean volume of the whole gland was about one-third of that found in control goats of similar sex and age. Pars distalis shrank to one-fifth of the volume of the normal lobe. This shrinkage was due largely to contraction of the scar replacing the original massive infarct, but partly also to shrinkage of the surviving parenchymal cells. The infundibular process also showed a severe reduction in size. By contrast pars intermedia underwent a substantial hypertrophy.

A long-term effect of subliminally presented words

2010 ◽  
Author(s):  
Andreas T. Breuer ◽  
Michael E. J. Masson ◽  
Glen E. Bodner
Keyword(s):  
Term Effect ◽  
Long Term Effect
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