Microbial Production of Short Chain Fatty Acids from Lignocellulosic Biomass: Current Processes and Market

Biological production of organic acids from conversion of biomass derivatives has received increased attention among scientists and engineers and in business because of the attractive properties such as renewability, sustainability, degradability, and versatility. The aim of the present review is to summarize recent research and development of short chain fatty acids production by anaerobic fermentation of nonfood biomass and to evaluate the status and outlook for a sustainable industrial production of such biochemicals. Volatile fatty acids (VFAs) such as acetic acid, propionic acid, and butyric acid have many industrial applications and are currently of global economic interest. The focus is mainly on the utilization of pretreated lignocellulosic plant biomass as substrate (the carbohydrate route) and development of the bacteria and processes that lead to a high and economically feasible production of VFA. The current and developing market for VFA is analyzed focusing on production, prices, and forecasts along with a presentation of the biotechnology companies operating in the market for sustainable biochemicals. Finally, perspectives on taking sustainable product of biochemicals from promise to market introduction are reviewed.

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Insight into the roles of ferric chloride on short-chain fatty acids production in anaerobic fermentation of waste activated sludge: Performance and mechanism

Chemical Engineering Journal ◽

10.1016/j.cej.2021.129809 ◽

2021 ◽

pp. 129809

Author(s):

Wei Zhan ◽

Lipin Li ◽

Yu Tian ◽

Yongjia Lei ◽

Wei Zuo ◽

...

Keyword(s):

Fatty Acids ◽

Activated Sludge ◽

Ferric Chloride ◽

Anaerobic Fermentation ◽

Short Chain Fatty Acids ◽

Short Chain ◽

Waste Activated Sludge ◽

Insight Into ◽

Performance And Mechanism ◽

Chain Fatty Acids

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Efficient production of short-chain fatty acids from anaerobic fermentation of liquor wastewater and waste activated sludge by breaking the restrictions of low bioavailable substrates and microbial activity

Bioresource Technology ◽

10.1016/j.biortech.2018.08.039 ◽

2018 ◽

Vol 268 ◽

pp. 549-557 ◽

Cited By ~ 24

Author(s):

Jingyang Luo ◽

Jing Wu ◽

Qin Zhang ◽

Qian Feng ◽

Lijuan Wu ◽

...

Keyword(s):

Fatty Acids ◽

Activated Sludge ◽

Microbial Activity ◽

Anaerobic Fermentation ◽

Short Chain Fatty Acids ◽

Short Chain ◽

Waste Activated Sludge ◽

Efficient Production ◽

Chain Fatty Acids

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Enhanced anaerobic fermentation of waste activated sludge by NaCl assistant hydrolysis strategy: Improved bio-production of short-chain fatty acids and feasibility of NaCl reuse

Bioresource Technology ◽

10.1016/j.biortech.2020.123303 ◽

2020 ◽

Vol 312 ◽

pp. 123303 ◽

Cited By ~ 1

Author(s):

Heliang Pang ◽

Jie Xu ◽

Junguo He ◽

Xinlei Pan ◽

Yingqun Ma ◽

...

Keyword(s):

Fatty Acids ◽

Activated Sludge ◽

Anaerobic Fermentation ◽

Short Chain Fatty Acids ◽

Short Chain ◽

Waste Activated Sludge ◽

Chain Fatty Acids

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An innovative alkaline protease-based pretreatment approach for enhanced short-chain fatty acids production via a short-term anaerobic fermentation of waste activated sludge

Bioresource Technology ◽

10.1016/j.biortech.2020.123397 ◽

2020 ◽

Vol 312 ◽

pp. 123397 ◽

Cited By ~ 3

Author(s):

Heliang Pang ◽

Xinlei Pan ◽

Lin Li ◽

Junguo He ◽

Yanshi Zheng ◽

...

Keyword(s):

Fatty Acids ◽

Activated Sludge ◽

Alkaline Protease ◽

Anaerobic Fermentation ◽

Short Chain Fatty Acids ◽

Short Chain ◽

Waste Activated Sludge ◽

Short Term ◽

Chain Fatty Acids

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Unveiling the mechanisms of how cationic polyacrylamide affects short-chain fatty acids accumulation during long-term anaerobic fermentation of waste activated sludge

Water Research ◽

10.1016/j.watres.2019.02.036 ◽

2019 ◽

Vol 155 ◽

pp. 142-151 ◽

Cited By ~ 78

Author(s):

Xuran Liu ◽

Qiuxiang Xu ◽

Dongbo Wang ◽

Yanxin Wu ◽

Qi Yang ◽

...

Keyword(s):

Fatty Acids ◽

Activated Sludge ◽

Anaerobic Fermentation ◽

Short Chain Fatty Acids ◽

Short Chain ◽

Waste Activated Sludge ◽

Cationic Polyacrylamide ◽

Chain Fatty Acids

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Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism

International Journal of Molecular Sciences ◽

10.3390/ijms21176356 ◽

2020 ◽

Vol 21 (17) ◽

pp. 6356 ◽

Cited By ~ 4

Author(s):

Jin He ◽

Peiwen Zhang ◽

Linyuan Shen ◽

Lili Niu ◽

Ya Tan ◽

...

Keyword(s):

Fatty Acids ◽

Lipid Metabolism ◽

Histone Deacetylases ◽

Anaerobic Fermentation ◽

Short Chain Fatty Acids ◽

Biological Properties ◽

Short Chain ◽

Signalling Pathways ◽

Glucose And Lipid Metabolism ◽

Chain Fatty Acids

Short-chain fatty acids (SCFAs), particularly acetate, propionate and butyrate, are mainly produced by anaerobic fermentation of gut microbes. SCFAs play an important role in regulating energy metabolism and energy supply, as well as maintaining the homeostasis of the intestinal environment. In recent years, many studies have shown that SCFAs demonstrate physiologically beneficial effects, and the signalling pathways related to SCFA production, absorption, metabolism, and intestinal effects have been discovered. Two major signalling pathways concerning SCFAs, G-protein-coupled receptors (GPRCs) and histone deacetylases (HDACs), are well recognized. In this review, we summarize the recent advances concerning the biological properties of SCFAs and the signalling pathways in inflammation and glucose and lipid metabolism.

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Feasibility of enhancing short-chain fatty acids production from sludge anaerobic fermentation at free nitrous acid pretreatment: Role and significance of Tea saponin

Bioresource Technology ◽

10.1016/j.biortech.2018.01.084 ◽

2018 ◽

Vol 254 ◽

pp. 194-202 ◽

Cited By ~ 51

Author(s):

Qiuxiang Xu ◽

Xuran Liu ◽

Jianwei Zhao ◽

Dongbo Wang ◽

Qilin Wang ◽

...

Keyword(s):

Fatty Acids ◽

Nitrous Acid ◽

Anaerobic Fermentation ◽

Short Chain Fatty Acids ◽

Short Chain ◽

Acid Pretreatment ◽

Free Nitrous Acid ◽

Tea Saponin ◽

Chain Fatty Acids

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Short-Chain Fatty Acids

10.32545/encyclopedia202005.0006.v2 ◽

2020 ◽

Author(s):

Paulina Markowiak-Kopeć ◽

Katarzyna Śliżewska

Keyword(s):

Fatty Acids ◽

Volatile Fatty Acids ◽

Short Chain Fatty Acids ◽

Short Chain ◽

Intestinal Microbiome ◽

Test Results ◽

And Function ◽

The Relationship ◽

Normal Health ◽

Chain Fatty Acids

The relationship between diet and the diversity and function of the intestinal microbiomeand its importance for human health is currently the subject of many studies. The type and proportionof microorganisms found in the intestines can determine the energy balance of the host. Intestinalmicroorganisms perform many important functions, one of which is participation in metabolicprocesses, e.g., in the production of short-chain fatty acids—SCFAs (also called volatile fatty acids).These acids represent the main carbon flow from the diet to the host microbiome. Maintainingintestinal balance is necessary to maintain the host’s normal health and prevent many diseases.The results of many studies confirm the beneficial effect of probiotic microorganisms on the balanceof the intestinal microbiome and produced metabolites, including SCFAs. The aim of this review is tosummarize what is known on the effects of probiotics on the production of short-chain fatty acidsby gut microbes. In addition, the mechanism of formation and properties of these metabolites isdiscussed and verified test results confirming the effectiveness of probiotics in human nutrition bymodulating SCFAs production by intestinal microbiome is presented.

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