scholarly journals Etiology of End-Stage Renal Disease and Arterial Stiffness among Hemodialysis Patients

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Balsam El Ghoul ◽  
Yazan Daaboul ◽  
Serge Korjian ◽  
Andrew El Alam ◽  
Anthony Mansour ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Nephropathy ◽  
Arterial Stiffness ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Hemodialysis Patients ◽  
Cross Sectional ◽  
History Of ◽  
Stage Renal Disease ◽  
End Stage

Background. Prior studies have demonstrated that conventional and emerging CV risk factors are associated with worsening arterial stiffness among end-stage renal disease (ESRD) patients on hemodialysis. The present cross-sectional study evaluates the association between the etiology of ESRD and arterial stiffness among a cohort of hemodialysis patients.Methods. Etiology of ESRD was identified from patients’ medical records and classified as either vascular renal disease, diabetic nephropathy, nondiabetic glomerulopathy, tubular interstitial nephropathy, hereditary nephropathy, or ESRD of unconfirmed etiology.Results. A total of 82 subjects were enrolled. cfPWV was independently associated with the composite of either diabetic nephropathy or vascular renal disease (p=0.022), pulse pressure (p=0.001), and a history of CV events (p=0.025), but not history of hypertension or diabetes mellitus alone. The median cfPWVs in diabetic nephropathy and vascular renal disease were comparable and significantly higher than median cfPWVs in other etiologies of ESRD.Conclusion. The study suggests that the etiology of ESRD is independently associated with arterial stiffness among hemodialysis patients. Furthermore, arterial stiffness was higher among patients who developed renal sequelae of either diabetes mellitus or hypertension as compared with those who have a history of either diabetes mellitus or hypertension alone.

scholarly journals Diabetic nephropathy as a cause of end-stage renal disease in Egypt: a six-year study

2004 ◽  
Vol 10 (4-5) ◽  
pp. 620-626 ◽  
Author(s):  
A. Afifi ◽  
M. El Setouhy ◽  
M. El Sharkawy ◽  
M. Ali ◽  
H. Ahmed ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Large Scale ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

The prevalence of diabetic nephropathy as a cause of end-stage renal disease [ESRD] in Egypt has been examined in small cross-sectional studies, with conflicting results. The need for a large-scale study prompted us to perform this 6-year multiple cross-sectional study. A sample of ESRD patients enrolled in the Egyptian renal data system was evaluated during the period 1996-2001 for the prevalence of diabetic nephropathy. Prevalence gradually increased from 8.9% in 1996, to 14.5% in 2001. The mean age of patients with diabetic nephropathy was significantly higher than that of patients with ESRD from other causes. Mortality was also significantly higher in diabetic patients with ESRD

scholarly journals Multicenter study of the causes of the end stage renal disease in patients on chronic hemodialysis in Minsk

2020 ◽  
Vol 17 (1) ◽  
pp. 49-54
Author(s):  
К. S. Komissarov
Keyword(s):  
Diabetes Mellitus ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Systemic Vasculitis ◽  
Chronic Hemodialysis ◽  
Kidney Damage ◽  
Chronic Glomerulonephritis ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage

The cross-sectional study of the patients receiving hemodialysis (HD) treatment in the dialysis departments in Minsk at the beginning of the year 2017 was made. The aim of the study was to define the main cause of the end stage renal disease (ESRD) among HD patients in the dialysis departments in Minsk. According to the inclusion and exclusion criteria, 289 patients were selected for further analysis. The median of the age was 57 (45; 66) years, for men it was 174 (60.2 %) years. The median of therapy duration was 26 (8; 66) months. The main cause of the end stage renal disease was chronic glomerulonephritis in 35.3 % of patients, the second was diabetes mellitus in 15.9 % of patients, and the third was the polycystic disease in 13.5 % of patients. Kidney damage in the frame of ANCA-vasculitis was revealed in 4 (1.4 %) patients, which is less than in Eastern European Centers where systemic vasculitis is the cause of ESRD in 6.7 % of cases. Histological verification of the diagnosis was conducted in 25 (8.7 %) patients while the most frequent diagnosis was IgA-nephropathy tht was defined in 44 % of biopsied persons. The results of our analysis point to an insufficient rate of histopathology that proved the diagnosis among of the HD patients in Minsk. It does not allow us to conduct a complete differential diagnosis between kidney damage due to the primary diffuse kidney disease or arterial hypertension, diabetes mellitus and systemic vacuities.

scholarly journals Diabetic nephropathy: what should cardiologist remember

2021 ◽  
Vol 23 (1) ◽  
pp. 20-24
Author(s):  
Natalia P. Trubitsyna ◽  
◽  
Natalia V. Zaitseva ◽  
Anastasia S. Severinа ◽  
◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Nephropathy ◽  
Renal Replacement Therapy ◽  
Renal Disease ◽  
Replacement Therapy ◽  
End Stage Renal Disease ◽  
Kidney Diseases ◽  
Renin Angiotensin Aldosterone System ◽  
Stage Renal Disease ◽  
End Stage

Prevalence of diabetes mellitus (DM) progressively increases around the world. Diabetic nephropathy (DN) is significant reason of end-stage renal disease and it is associated with high risk of cardiovascular disease and mortality. Necessity of expensive renal replacement therapy for patients with prominent vascular diabetic complications and end-stage renal disease has significant socio-economic impact. DM, as a one of leading causes of kidney diseases, competes for stricted resources of public health. Renal replacement therapy in patients with DM does not solve the whole problem, because survival of such patients is low, comparing with another kidney diseases, first of all because of cardiovascular diseases. Good control of glycaemia, blood pressure and cholesterol level and prescription of renin-angiotensin-aldosterone system inhibitors and statins decrease cardiovascular risk and slow down DN progression, as it was shown in many clinical trials. So patients with DM and DN should receive complex therapy for risk reduction of kidney disease and cardiovascular disorders progression. Keywords: diabetes mellitus type 2, diabetic nephropathy, nephroprotection, cardioprotection, SGLT-2 inhibitors, GLP-1 agonists, renin-angiotensin-aldosterone system For citation: Trubitsyna NP, Zaitseva NV, Severinа AS. Diabetic nephropathy: what should cardiologist remember. Consilium Medicum. 2021; 23 (1): 20–24. DOI: 10.26442/20751753.2021.1.200712

scholarly journals Prevalence of Newly Diagnosed End-Stage Renal Disease Patients in a Tertiary Hospital of Central Nepal, Chitwan: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (233) ◽  
Author(s):  
Madhav Ghimire ◽  
Shreeju Vaidya ◽  
Hari Prasad Upadhyay
Keyword(s):  
Diabetes Mellitus ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Cross Sectional Study ◽  
Newly Diagnosed ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage

Introduction: End-stage renal disease patients are in rising trend globally, and they have been foundto occur predominantly in developing countries. Many studies have been published before, withinand across the countries, to know the clinicodemographic profile of end-stage renal disease patients.However, no such studies were done in Chitwan, Nepal. This study’s main objective was to find theprevalence of newly diagnosed end-stage renal disease patients. Methods: A hospital-based descriptive cross-sectional study was carried out in the Department ofNephrology from May 2016 to April 2019. Convenient sampling was done, and all the consecutivenew end-stage renal disease patients were included in the study. The ethical approval was takenfrom the Institutional Review Committee (reference number. 2016/COMSTH/IRC/042). Theprevalence and demographic profile of new end-stage renal disease patients were studied. The datawere analyzed with appropriate statistical tools. Results: A total of 250 new end-stage renal disease patients were found among 2200 admittedpatients. The prevalence of new end-stage renal disease was found to be 250 (11.36%). Out of 250patients, males were 156 (62.4%), and females were 94 (37.6%). The mean age was 49.6±15.5 years. Thecommonest cause of the incident end-stage renal disease was Type 2 Diabetes mellitus 89 (35.6%). Conclusions: The prevalence of new end-stage renal disease was found to be quite high. Thecommonest cause of the incident end-stage renal disease was Type 2 Diabetes Mellitus.

scholarly journals HUBUNGAN ANTARA JENIS TERAPI HIPERTENSI PADA ANGKA KEJADIAN GAGAL GINJAL DI RSUD DR. R. SOEDJONO SELONG

2019 ◽  
Vol 4 (1) ◽  
pp. 679
Author(s):  
Muhammad Nauval ◽  
Uswatun Hasanah
Keyword(s):  
Diabetes Mellitus ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Odds Ratio ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage

Hipertensi merupakan penyebab utama terjadinya end-stage renal disease (ERDS) bersama dengan diabetes mellitus. Hipertensi yang berlangsung lama dapat mengakibatkan perubahan-perubahan struktur pada arteriol di seluruh tubuh, ditandai dengan fibrosis dan sklerosis dinding pembuluh darah. Organ sasaran utama keadaan ini adalah salah satunya ginjal. Beratnya pengaruh hipertensi pada ginjal tergantung dari tingginya tekanan darah dan lamanya menderita hipertensi. Semakin tinggi tekanan darah dalam waktu lama maka semakin berat komplikasi yang dapat ditimbulkan. Pemberian terapi hipertensi yang adekuat akan dapat mencegah komplikasi yang di timbulkan oleh penyakit hipertensi. Terapi kombinasi diberikan untuk meningkatkan kontrol tekanan darah dalam batas normal pada penderita hipertensi.Subjek penelitian merupakan pasien hipertensi kronis dengan lama hipertensi > 3 tahun. Jumlah sample dalam penelitian ini adalah 79 orang. Pengambilan data dilakukan dengan penelusuran rekam medis pasien hipertensi kronis yang berobat di RSUD DR. R Soedjono selong. Subjek pria sebanyak 35 orang (44,3%) dan wanita 44 orang (55,7%). Sebanyak 34 (43,03%) orang mendapatkan monoterapi, dan 45 (56,96%) orang lainnya menerima terapi kombinasi.Jenis penelitian ini adalah observasional analitik dengan pendekatan rancangan Cross sectional. Tempat penelitian dilaksanakan di Rumah Sakit Umum Daerah Dr. R. Soedjono Selong. Waktu penelitian dilaksanakan pada bulan April-Mei 2017.Hasil Uji Chi Kuadrat (X2) diperoleh nilai signifikan 0,001 (p<0,05) dan CI 95% 1.106-1.303, berarti terdapat hubungan bermakna antara jenis terapi hipertensi dengan kejadian gagal ginjal pada RSUD DR. R. Soedjono Selong. Odds Ratio (OR) di dapatkan sebesar 5.147. (CI 95% : 1.960-13.513) menunjukkan terdapat hubungan yang bermakna antara jenis terapi hipertensi dengan kejadian gagal ginjal.  

scholarly journals Etiology of end-stage renal disease amongst hemodialysis patients in Makkah city, Saudi Arabia

2021 ◽  
Vol 8 (6) ◽  
pp. 11-15
Author(s):  
Qadhi et al. ◽  
Keyword(s):  
Saudi Arabia ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Urinary Tract Obstruction ◽  
Hemodialysis Patients ◽  
Drug Misuse ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage ◽  
Makkah City

In recent years, the number of hemodialysis (HD) patients has increased in the Kingdom of Saudi Arabia. End-stage renal disease (ESRD) is associated with increased rates of hospital admission, morbidity, and mortality. Globally, the most common causes of ESRD are diabetic nephropathy, hypertension, glomerulonephritis, infections, and chronic obstruction. However, very limited data have been presented regarding the etiology of ESRD in Saudi Arabia, especially in Makkah City. Therefore, this cross-sectional study is designed to determine the underlying etiologies of ESRD in hemodialysis patients. The study was conducted among 306 patients who were recruited from Makkah hospitals and HD centers. The obtained data showed that diabetes was the most common cause of ESRD (34.3%), followed by hypertension (20.9%), drug misuse (12.1%), hereditary conditions (10.1%), urinary tract obstruction, and urinary retention (9.8%), unknown reason (8.2%), and chronic inflammation of the kidneys (3.3%). In conclusion, this study highlights the most important factors contributing to ESRD in the Makkah region. Thus, national campaigns should be performed to increase awareness about these factors and to possibly reduce the incidence of the disease.

Sign in / Sign up

Export Citation Format

Share Document