Multicenter study of the causes of the end stage renal disease in patients on chronic hemodialysis in Minsk

The cross-sectional study of the patients receiving hemodialysis (HD) treatment in the dialysis departments in Minsk at the beginning of the year 2017 was made. The aim of the study was to define the main cause of the end stage renal disease (ESRD) among HD patients in the dialysis departments in Minsk. According to the inclusion and exclusion criteria, 289 patients were selected for further analysis. The median of the age was 57 (45; 66) years, for men it was 174 (60.2 %) years. The median of therapy duration was 26 (8; 66) months. The main cause of the end stage renal disease was chronic glomerulonephritis in 35.3 % of patients, the second was diabetes mellitus in 15.9 % of patients, and the third was the polycystic disease in 13.5 % of patients. Kidney damage in the frame of ANCA-vasculitis was revealed in 4 (1.4 %) patients, which is less than in Eastern European Centers where systemic vasculitis is the cause of ESRD in 6.7 % of cases. Histological verification of the diagnosis was conducted in 25 (8.7 %) patients while the most frequent diagnosis was IgA-nephropathy tht was defined in 44 % of biopsied persons. The results of our analysis point to an insufficient rate of histopathology that proved the diagnosis among of the HD patients in Minsk. It does not allow us to conduct a complete differential diagnosis between kidney damage due to the primary diffuse kidney disease or arterial hypertension, diabetes mellitus and systemic vacuities.

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Etiology of End-Stage Renal Disease and Arterial Stiffness among Hemodialysis Patients

BioMed Research International ◽

10.1155/2017/2543262 ◽

2017 ◽

Vol 2017 ◽

pp. 1-6 ◽

Cited By ~ 5

Author(s):

Balsam El Ghoul ◽

Yazan Daaboul ◽

Serge Korjian ◽

Andrew El Alam ◽

Anthony Mansour ◽

...

Keyword(s):

Diabetes Mellitus ◽

Diabetic Nephropathy ◽

Arterial Stiffness ◽

Renal Disease ◽

End Stage Renal Disease ◽

Hemodialysis Patients ◽

Cross Sectional ◽

History Of ◽

Stage Renal Disease ◽

End Stage

Background. Prior studies have demonstrated that conventional and emerging CV risk factors are associated with worsening arterial stiffness among end-stage renal disease (ESRD) patients on hemodialysis. The present cross-sectional study evaluates the association between the etiology of ESRD and arterial stiffness among a cohort of hemodialysis patients.Methods. Etiology of ESRD was identified from patients’ medical records and classified as either vascular renal disease, diabetic nephropathy, nondiabetic glomerulopathy, tubular interstitial nephropathy, hereditary nephropathy, or ESRD of unconfirmed etiology.Results. A total of 82 subjects were enrolled. cfPWV was independently associated with the composite of either diabetic nephropathy or vascular renal disease (p=0.022), pulse pressure (p=0.001), and a history of CV events (p=0.025), but not history of hypertension or diabetes mellitus alone. The median cfPWVs in diabetic nephropathy and vascular renal disease were comparable and significantly higher than median cfPWVs in other etiologies of ESRD.Conclusion. The study suggests that the etiology of ESRD is independently associated with arterial stiffness among hemodialysis patients. Furthermore, arterial stiffness was higher among patients who developed renal sequelae of either diabetes mellitus or hypertension as compared with those who have a history of either diabetes mellitus or hypertension alone.

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Prevalence of Newly Diagnosed End-Stage Renal Disease Patients in a Tertiary Hospital of Central Nepal, Chitwan: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association ◽

10.31729/jnma.4971 ◽

2021 ◽

Vol 59 (233) ◽

Author(s):

Madhav Ghimire ◽

Shreeju Vaidya ◽

Hari Prasad Upadhyay

Keyword(s):

Diabetes Mellitus ◽

Renal Disease ◽

End Stage Renal Disease ◽

Cross Sectional Study ◽

Newly Diagnosed ◽

Sectional Study ◽

Cross Sectional ◽

Stage Renal Disease ◽

End Stage

Introduction: End-stage renal disease patients are in rising trend globally, and they have been foundto occur predominantly in developing countries. Many studies have been published before, withinand across the countries, to know the clinicodemographic profile of end-stage renal disease patients.However, no such studies were done in Chitwan, Nepal. This study’s main objective was to find theprevalence of newly diagnosed end-stage renal disease patients. Methods: A hospital-based descriptive cross-sectional study was carried out in the Department ofNephrology from May 2016 to April 2019. Convenient sampling was done, and all the consecutivenew end-stage renal disease patients were included in the study. The ethical approval was takenfrom the Institutional Review Committee (reference number. 2016/COMSTH/IRC/042). Theprevalence and demographic profile of new end-stage renal disease patients were studied. The datawere analyzed with appropriate statistical tools. Results: A total of 250 new end-stage renal disease patients were found among 2200 admittedpatients. The prevalence of new end-stage renal disease was found to be 250 (11.36%). Out of 250patients, males were 156 (62.4%), and females were 94 (37.6%). The mean age was 49.6±15.5 years. Thecommonest cause of the incident end-stage renal disease was Type 2 Diabetes mellitus 89 (35.6%). Conclusions: The prevalence of new end-stage renal disease was found to be quite high. Thecommonest cause of the incident end-stage renal disease was Type 2 Diabetes Mellitus.

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Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD)

Proceedings of Shaikh Zayed Medical Complex Lahore - October to December ◽

10.47489/pszmc-811-35-3-64-68 ◽

2021 ◽

Vol 35 (3) ◽

pp. 64-68

Author(s):

Rakesh Bahadur Adhikari

Keyword(s):

Pulmonary Hypertension ◽

Renal Disease ◽

Right Ventricular ◽

End Stage Renal Disease ◽

Chronic Hemodialysis ◽

Dialysis Session ◽

Systolic Pulmonary Artery Pressure ◽

Cross Sectional ◽

Stage Renal Disease ◽

End Stage

Introduction: Chronic hemodialysis (HD) ends up with right ventricular (RV) dysfunction and increased pulmonary hypertension (PHTN). Left to right shunt in dialysis patients due to arterio-venous fistula (AVF) causes chronic volume overload, independent of rise in body water leading to worsening RV overload and RV dysfunction (RVD). Aims & Objectives: To determine the prevalence of RV dysfunction & pulmonary hypertension and its relationship to the number of dialysis sessions in patients of ESRD. Place and duration of study: Department of Cardiology & Nephrology, Sheikh Zayed Hospital, Lahore for one year from March 2016 - March 2017. Material & Methods: This cross-sectional analytical hospital based study enrolled 145 Patients of End-Stage Renal Disease (ESRD) on regular 4-hours HD sessions at two or more times per week for at least 3 months. Echocardiography (Echo) with 2-D, M (Motion) Mode & Doppler studies were done. RV dysfunction by TAPSE value less than 15mm & PHTN by Systolic pulmonary artery pressure >35 mm Hg or tricuspid regurgitation velocity (VTR) ?2m/s at rest were noted. Data was analyzed on SPSS version 20. Results: RV dysfunction was seen in 40.7% (59) of patients and the frequency rose across the 4 dialysis session groups (13.8%, 37.3%, 51.7% & 100%, p<0.001). PHTN was observed in 44.1% of the patients and the prevalence progressively increased across the groups (17.2%, 45.1%, 53.3% & 80.01%, p<0.003). There was significant association between RVD and PHTN (p=0.011). Conclusion: We observed positive correlation between RV dysfunction and PHTN with total number of hemodialysis sessions. Early detection of sub-clinical RV dysfunction may improve mortality and morbidity by optimizing treatment options.

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HUBUNGAN ANTARA JENIS TERAPI HIPERTENSI PADA ANGKA KEJADIAN GAGAL GINJAL DI RSUD DR. R. SOEDJONO SELONG

JURNAL KEDOKTERAN ◽

10.36679/kedokteran.v4i1.58 ◽

2019 ◽

Vol 4 (1) ◽

pp. 679

Author(s):

Muhammad Nauval ◽

Uswatun Hasanah

Keyword(s):

Diabetes Mellitus ◽

Renal Disease ◽

End Stage Renal Disease ◽

Odds Ratio ◽

Cross Sectional ◽

Stage Renal Disease ◽

End Stage

Hipertensi merupakan penyebab utama terjadinya end-stage renal disease (ERDS) bersama dengan diabetes mellitus. Hipertensi yang berlangsung lama dapat mengakibatkan perubahan-perubahan struktur pada arteriol di seluruh tubuh, ditandai dengan fibrosis dan sklerosis dinding pembuluh darah. Organ sasaran utama keadaan ini adalah salah satunya ginjal. Beratnya pengaruh hipertensi pada ginjal tergantung dari tingginya tekanan darah dan lamanya menderita hipertensi. Semakin tinggi tekanan darah dalam waktu lama maka semakin berat komplikasi yang dapat ditimbulkan. Pemberian terapi hipertensi yang adekuat akan dapat mencegah komplikasi yang di timbulkan oleh penyakit hipertensi. Terapi kombinasi diberikan untuk meningkatkan kontrol tekanan darah dalam batas normal pada penderita hipertensi.Subjek penelitian merupakan pasien hipertensi kronis dengan lama hipertensi > 3 tahun. Jumlah sample dalam penelitian ini adalah 79 orang. Pengambilan data dilakukan dengan penelusuran rekam medis pasien hipertensi kronis yang berobat di RSUD DR. R Soedjono selong. Subjek pria sebanyak 35 orang (44,3%) dan wanita 44 orang (55,7%). Sebanyak 34 (43,03%) orang mendapatkan monoterapi, dan 45 (56,96%) orang lainnya menerima terapi kombinasi.Jenis penelitian ini adalah observasional analitik dengan pendekatan rancangan Cross sectional. Tempat penelitian dilaksanakan di Rumah Sakit Umum Daerah Dr. R. Soedjono Selong. Waktu penelitian dilaksanakan pada bulan April-Mei 2017.Hasil Uji Chi Kuadrat (X2) diperoleh nilai signifikan 0,001 (p<0,05) dan CI 95% 1.106-1.303, berarti terdapat hubungan bermakna antara jenis terapi hipertensi dengan kejadian gagal ginjal pada RSUD DR. R. Soedjono Selong. Odds Ratio (OR) di dapatkan sebesar 5.147. (CI 95% : 1.960-13.513) menunjukkan terdapat hubungan yang bermakna antara jenis terapi hipertensi dengan kejadian gagal ginjal.

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