Osteoid Osteoma of the Trapezium: Case Report of an Unusual Tumor Location Presenting a Diagnostic Challenge

Osteoid osteoma is a benign bone tumor, which represents approximately 10% of all benign bone tumors. When localized to the carpus, osteoid osteomas are most often seen in the scaphoid and capitate. Rarely, these tumors can also be observed in the trapezium. Given the infrequency with which osteomas are located in the trapezium and often nonspecific presenting symptoms, diagnosis of this tumor can be challenging and requires a high index of suspicion.

Download Full-text

Osteoblastoma

Archives of Pathology & Laboratory Medicine ◽

10.5858/2010-0201-cr.1 ◽

2010 ◽

Vol 134 (10) ◽

pp. 1460-1466 ◽

Cited By ~ 12

Author(s):

David R. Lucas

Keyword(s):

Case Report ◽

Bone Tumor ◽

Bone Tumors ◽

Differential Diagnoses ◽

Benign Bone Tumor ◽

Benign Bone Tumors ◽

Pathologic Features ◽

Clinicopathologic Findings

Abstract Osteoblastoma is a rare benign bone tumor. Although the histologic features in most cases are distinctive, there are various permutations that make the diagnosis challenging. It can mimic a variety of other benign bone tumors, but more importantly, distinguishing it from osteoblastoma-like osteosarcoma can be difficult. In this case report, I describe the clinicopathologic findings for a 13-year-old adolescent boy with T7 spinal osteoblastoma and review salient clinical, radiographic, and pathologic features of osteoblastoma, as well as the differential diagnoses.

Download Full-text

Complications of Computer Tomography Assisted Radiofrequency Ablation in the Treatment of Osteoid Osteoma

BioMed Research International ◽

10.1155/2019/4376851 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

Yunus Oc ◽

Bekir Eray Kilinc ◽

Sahin Cennet ◽

Mehmet Metin Boyacioglu ◽

Rodi Ertugrul ◽

...

Keyword(s):

Radiofrequency Ablation ◽

Osteoid Osteoma ◽

Bone Tumors ◽

Skin Infection ◽

Primary Bone Tumors ◽

Benign Bone Tumors ◽

Superficial Skin ◽

Primary Bone ◽

A Prospective Study

Background. Osteoid osteoma (OO) is one of the most commonly occurring benign bone tumors. It constitutes 10-12% of benign bone tumors and 2-3% of primary bone tumors. In radiofrequency ablation (RFA) treatment, the cells of the tumor are thermally inactivated by the help of electrodes shaped like needles. In our study, we aimed to show the major and minor complications in patients undergoing RFA and to show what should be done to prevent these complications. Methods. The study was carried out as a prospective study on the follow-up of 87 osteoid osteoma patients treated between 2015 and 2017. The youngest of the patients was 1 year old and the oldest was 42 years old. The RFA procedure lasted 10 min on average, excluding anesthesia and preparation. All lesions were ablated at 90 degrees for 7 minutes with the heat increased gradually. All patients were followed up for 1 day in the orthopedics clinic. Results. Complications were observed in 7 patients. The lesions with the most complications were observed to be in the tibia, second-degree burns were seen in 2 patients, and superficial skin infection was observed in 2 patients. In 1 patient, the probe tip was broken and remained within the bone. Intramuscular hematoma was detected in 1 lesion located in the proximal femur. A complaint of numbness in the fingers developed in a lesion located in the metacarpus. Conclusion. Preventive measures should be taken before the procedure in order to prevent minor complications, and, for major complications, close follow-up should be done after the procedure and patients should be kept away from heavy physical activities for the first 3 months.

Download Full-text

Demographic, clinico-pathological features and management pattern of primary bone tumors in a tertiary care hospital of South India

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20214962 ◽

2021 ◽

Vol 8 (1) ◽

pp. 60

Author(s):

Subbiah Shanmugam ◽

Sujay Susikar ◽

Bharanidharan T. ◽

Arun Victor Jebasingh

Keyword(s):

Bone Tumor ◽

Bone Tumors ◽

Tertiary Care ◽

Tumor Location ◽

Care Hospital ◽

Pathological Features ◽

Primary Bone Tumor ◽

Primary Bone Tumors ◽

True Incidence ◽

Primary Bone

Background: Primary bone tumors are very rare tumors. The true incidence of bone tumors is not well established and is under reported due to rarity and lack of accurate registries. Hence it is essential to study about the demographic, clinico-pathological features and the pattern of surgical management of bone tumors. The aim of this study is to analyze the demographic and clinico-pathological features of primary bone tumors that were managed by surgery.Methods: A retrospective analysis of all patients with primary bone tumor who were treated by surgery from 2012 to 2019 was done. The age, sex distribution, histopathology, location of the tumor and surgical procedure done were analyzed.Results: Among 103 patients analyzed, 66 (64%) were men and 37 (36%) were women. Primary bone tumors most commonly presented in 11 to 20 years of age with 35 (33.9%) patients occurring in this age group. Osteosarcoma was the most common primary bone tumor and it occurred in 49 (47.6%) patients, out of which 34 (69.3%) patients were below 20 years of age. Giant cell tumor was the most common benign bone tumor and it occurred in 22 patients, out of which nine (40.9%) patients were of age 21 to 30 years. Distal femur was the most common site with 39 (37.9%) patients. The limb preservation rate for malignant appendicular bone tumors was 69.0%.Conclusions: The diagnosis of bone tumor depends not only on histopathological features but also needs correlation with age, clinical features, tumor location and radiological features for confirmation of diagnosis.

Download Full-text

Osteochondroma of the Mandibular Condyle

Journal of Contemporary Dentistry ◽

10.5005/jp-journals-10031-1021 ◽

2012 ◽

Vol 2 (3) ◽

pp. 106-108 ◽

Cited By ~ 1

Author(s):

Jyotsna Galinde ◽

Sushrut Vaidya ◽

Sunil Sidana ◽

Srivalli Natrajan

Keyword(s):

Case Report ◽

Head And Neck ◽

Bone Tumor ◽

Mandibular Condyle ◽

Neck Region ◽

Rare Tumor ◽

Benign Bone Tumor ◽

Head And Neck Region ◽

Condylar Process ◽

Condylar Hyperplasia

ABSTRACT Osteochondroma is the most common benign bone tumor but rare in the head and neck region because of intramembranous origin of craniofacial bones. In the head and neck it occurs most commonly at tip of coronoid or condylar process. Clinically features can mimic condylar hyperplasia. This case report adds to the growing knowledge about this rare tumor. How to cite this article Vaidya S, Sidana S, Galinde J, Natrajan S. Osteochondroma of the Mandibular Condyle. J Contemp Dent 2012;2(3):106-108.

Download Full-text

KPNA2 expression is a potential marker for differential diagnosis between osteosarcomas and other malignant bone tumor mimics

Diagnostic Pathology ◽

10.1186/s13000-020-01051-6 ◽

2020 ◽

Vol 15 (1) ◽

Author(s):

Lucen Jiang ◽

Jianghuan Liu ◽

Qingzhu Wei ◽

Yiyang Wang

Keyword(s):

Differential Diagnosis ◽

Bone Tumor ◽

Bone Tumors ◽

Bone Sarcoma ◽

Malignant Bone Tumor ◽

Diagnostic Biomarker ◽

Malignant Bone Tumors ◽

Benign Bone Tumors ◽

Potential Marker ◽

Osteoblastic Osteosarcoma

Abstract Background Karyopherin α2 (KPNA2), a member of the karyopherin α family, has been studied in several cancers but has not yet been substantially investigated in malignant bone tumors. The purpose of the current study was to evaluate the KPNA2 expression level and its utility as a novel diagnostic biomarker in osteosarcomas and malignant bone tumor mimics, such as chondrosarcomas and Ewing sarcomas (ESs). Method We investigated the expression of KPNA2 protein by immunohistochemistry on paraffin-embedded surgical specimens from 223 patients with malignant and benign bone tumors, including 81 osteosarcomas, 42 chondrosarcomas, 15 ESs, 28 osteoid osteomas, 20 osteochondromas and 37 chondroblastomas. Immunoreactivity was scored semiquantitatively based on staining extent and intensity. Results Sixty-seven of 81 (82.7%) osteosarcoma, zero of 42 (0%) chondrosarcoma and one of 15 (6.7%) ES samples showed immunoreactivity for KPNA2. Negative KPNA2 expression was observed in all benign bone tumors. The expression of KPNA2 in osteosarcoma samples was much higher than that in chondrosarcoma and ES samples (P < 0.001). The sensitivity and specificity of KPNA2 immunoexpression for detecting osteosarcoma were 82.7 and 100%, respectively. Several subtypes of osteosarcoma were analyzed, and immunostaining of KPNA2 was frequent in osteoblastic samples (90.9%), with 39 samples (70.9%) showing strong-intensity staining. KPNA2 positivity was observed in ten of 13 (76.9%) chondroblastic, two of 6 (33.3%) fibroblastic, three of 4 (75%) telangiectatic and two of 3 (66.7%) giant cell-rich osteosarcoma samples. The strongest intensity staining was observed in osteoblastic osteosarcoma. Conclusion KPNA2 is frequently expressed in osteosarcomas, particularly in osteoblastic and chondroblastic tumors, but is rarely positive in chondrosarcomas and ESs. This feature may aid in distinguishing between osteosarcoma and other bone sarcoma mimics. This report supports KPNA2 as a novel marker for the diagnosis of osteosarcoma.

Download Full-text

Giant osteoblastoma of temporal bone: case report

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x1998000200021 ◽

1998 ◽

Vol 56 (2) ◽

pp. 292-295 ◽

Cited By ~ 7

Author(s):

EBERVAL GADELHA FIGUEIREDO ◽

EDUARDO VELLUTINI ◽

OCTÁVIO VELASCO ◽

MÁRIO SIQUEIRA ◽

PATRÍCIA BOUGAR

Keyword(s):

Case Report ◽

Temporal Bone ◽

Bone Tumor ◽

Bone Tumors ◽

External Carotid ◽

Total Removal ◽

Skull Tumor ◽

Benign Osteoblastoma

Benign osteoblastoma is an uncommon bone tumor accounting for approximately 1% of all bone tumors. There are only 35 cases of skull osteoblastoma reported in the literature. We describe the case of a 23 year old male with a giant osteoblastoma of temporal bone submitted to a total removal of the tumor after an effective embolization of all external carotid branches. The authors discuss diagnostic and management aspects of this uncommon skull tumor.

Download Full-text

Percutaneous Treatments of Benign Bone Tumors

Seminars in Interventional Radiology ◽

10.1055/s-0038-1673640 ◽

2018 ◽

Vol 35 (04) ◽

pp. 324-332 ◽

Cited By ~ 5

Author(s):

Roberto Cazzato ◽

Andrew Gilkison ◽

Jean Caudrelier ◽

Julien Garnon ◽

Afshin Gangi ◽

...

Keyword(s):

Surgical Treatment ◽

Bone Tumors ◽

Percutaneous Treatment ◽

Percutaneous Ablation ◽

Benign Bone Tumor ◽

Mechanical Stabilization ◽

Benign Bone Tumors ◽

Image Guided ◽

Tumor Types ◽

Historical Management

AbstractBenign bone tumors consist of a wide variety of neoplasms that do not metastasize but can still cause local complications. Historical management of these tumors has included surgical treatment for lesion resection and possible mechanical stabilization. Initial percutaneous ablation techniques were described for osteoid osteoma management. The successful experience from these resulted in further percutaneous image-guided techniques being attempted, and in other benign bone tumor types. In this article, we present the most common benign bone tumors and describe the available results for the percutaneous treatment of these lesions.

Download Full-text

Intraosseous arteriovenous shunt of lumbar spine mimicking a benign bone tumor: A case report and short review of the literature

Interdisciplinary Neurosurgery ◽

10.1016/j.inat.2019.100625 ◽

2020 ◽

Vol 19 ◽

pp. 100625

Author(s):

Elias Antoniades ◽

Eleftherios Galidis ◽

Kyriaki Papadopoulou ◽

Athanasios Spiliotopoulos

Keyword(s):

Case Report ◽

Lumbar Spine ◽

Bone Tumor ◽

Short Review ◽

Arteriovenous Shunt ◽

Benign Bone Tumor ◽

Review Of The Literature

Download Full-text

A Giant Egg-like symptomatic Loose Body in the Peritoneal Cavity: A Case Report

Ethiopian Journal of Health Sciences ◽

10.4314/ejhs.v29i6.16 ◽

1970 ◽

Vol 29 (6) ◽

Author(s):

Berhanetsehay Teklewold ◽

Anteneh Kehaliw ◽

Melat Teka ◽

Bereket Berhane

Keyword(s):

Abdominal Pain ◽

Case Report ◽

Incidental Finding ◽

Loose Body ◽

Loose Bodies ◽

Diagnostic Challenge ◽

First Case ◽

Appendices Epiploicae ◽

The One ◽

High Index Of Suspicion

Background: Peritoneal loose bodies are rare lesions that are usually found as an incidental finding during abdominal surgery. Large loose bodies, measuring more than 5 cm, are rare and only a few cases are reported in the literature. Peritoneal loose bodies are usually infarcted appendices epiploicae, which become detached and appear as a peritoneal loose body in the abdominal cavity.Case Presentation: We report here the first case, in the local Ethiopian context, of a giant “egg-like” loose peritoneal body measuring 7 × 6 cm found in a 50-year-old man who presented with a cramping abdominal pain and features of abdominal obstruction. The current hypothesis as regards these bodies and the diagnostic challenges is discussed.Conclusion: Small peritoneal loose bodies are common but giant and symptomatic ones’, like the one discussed here, are very rare and a diagnostic challenge. And, in the context of intestinal obstruction, a high index of suspicion is needed in order to diagnose them.

Download Full-text

A narrative review on the characteristics and treatment of benign and malignant bone tumors

Acta Facultatis Medicae Naissensis ◽

10.5937/afmnai2004325b ◽

2020 ◽

Vol 37 (4) ◽

pp. 325-336

Author(s):

Frydoni Bahrami ◽

Esmaeilnejad-Ganji Mokhtar

Keyword(s):

Bone Tumor ◽

Bone Tumors ◽

Distal Femur ◽

Proximal Tibia ◽

Health Workers ◽

The Body ◽

Malignant Bone Tumors ◽

Benign Bone Tumors ◽

Malignant Lesions ◽

Cartilaginous Tumors

Bone tumors, including benign and malignant lesions, are not metastatic; however, they may appear in any part of the body skeleton. Distal femur and proximal tibia (around the knee joint) are the most prevalent sites. Most benign bone tumors are cartilaginous tumors, known as osteochondromas. Based on the reports, benign bone tumors are more frequent than primary malignant ones. Malignant bone tumor is another type of bone tumor, which usually occurs within the first years of life. As a result, it can considerably affect the lives of patients and their families. These tumors consist of osteosarcoma, chondrosarcoma, and Ewing's sarcoma. This article discusses the epidemiology, characteristics, and treatment of the most important types of benign and malignant bone tumors. These data will be useful to the physicians and other health workers to better understand the conditions of bone tumors and their management.

Download Full-text