scholarly journals Milk Hygiene in Rural Southwestern Uganda: Prevalence of Mastitis and Antimicrobial Resistance Profiles of Bacterial Contaminants of Milk and Milk Products

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Paul Ssajjakambwe ◽  
Gloria Bahizi ◽  
Christopher Setumba ◽  
Stevens M. B. Kisaka ◽  
Patrick Vudriko ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Production Efficiency ◽  
Sub Saharan Africa ◽  
Milk Products ◽  
E Coli ◽  
Antimicrobial Sensitivity ◽  
Causative Agents ◽  
Sub Saharan ◽  
The Government ◽  
Milk Hygiene

Mastitis and antimicrobial resistance are a big challenge to the dairy industry in sub-Saharan Africa. A study was conducted in Kashongi and Keshunga subcounties of Kiruhura District (in Uganda) where the government and private sector have deliberate programs to improve production efficiency, quality, and safety of milk and its products. The study aimed to determine the prevalence of mastitis, its common causative agents, antimicrobial sensitivity of mastitis causing organisms, and contaminants of processed milk products: yoghurt and ghee. Seventy-one milk, fourteen yoghurt, and three ghee samples were collected from nine farms. Of the 71 cows tested, 54 (76.1%) had mastitis. The mastitis cases from Keshunga were 32 (59.3%) and Kashongi contributed 22 (40.7%) of the cases. The common mastitis causative agents wereStaphylococcusspp. (30.8%),Streptococcusspp. (12.3%),Corynebacteriumspp.(15.4%), andE. coli(7.7%). Some of the isolates were resistant to tetracycline and penicillin. Prevalent contaminants of yoghurt wereStaphylococcusspp. (8.3%),Streptococcusspp. (8.3%),Corynebacteriumspp. (8.3%), andE. coli(8.3%), whereas all ghee containedStreptococcusspp. (100%). Prevalence of mastitis, antimicrobial resistance, and contamination of milk products are high in the study area. Targeted programs to prevent and control mastitis as well as antibiotic resistance are recommended.

scholarly journals Prevalence and antibiotic resistance of bacterial pathogens isolated from childhood diarrhoea in four provinces of Kenya

2012 ◽  
Vol 6 (07) ◽  
pp. 572-578 ◽  
Author(s):  
Willie Kipkemboi Sang ◽  
Valerie Oundo ◽  
David Schnabel
Keyword(s):  
Antimicrobial Resistance ◽  
Rural Areas ◽  
Hospital Admissions ◽  
Sub Saharan Africa ◽  
Vibrio Cholera ◽  
Antimicrobial Drug Resistance ◽  
E Coli ◽  
Shigella Isolate ◽  
Stool Samples ◽  
Sub Saharan

Introduction: Diarrhoea is one of the main causes of morbidity and mortality among children in sub-Saharan Africa, and one of the main causes of hospital admissions in rural areas of Kenya. In Kenya, antimicrobial resistance surveillance has been conducted only at the institutional levels, with limited sharing of information and analysis of data. As a result, the actual scale of regional or national antimicrobial drug resistance is not well defined. Methodology: Stool samples were collected between 1 October 2007 and 30 September 2008 from a total of 651 outpatients with diarrhoea who were under five years of age in four provinces of Kenya.  Conventional, biochemical methods, multiplex PCR and antimicrobial susceptibility were conducted to identify the bacterial causes and virulence factors in the isolates, respectively.  Results: Of the 651 patients screened, we identified the causes of 115 cases (17.7%) as follows: Pathogenic E. coli (11.2%) [enteroaggregative (8.9%), enterotoxigenic (1.2%), enteroinvasive (0.6%), shigatoxigenic (0.5%)], Salmonella (3.5%), Shigella (2%) and Vibrio cholera O1 (0.7%). The highest levels of resistance among the E. coli isolates were observed in ampicillin and trimethoprim/sulphamethoxazole each at 95% followed by tetracycline at 81%. Shigella isolate levels of resistance ranged from 80% to 100% for ampicillin, tetracycline and trimethoprim/sulphamethoxazole. Conclusion: The highest prevalence of antimicrobial resistance was to ampicillin followed by trimethoprim/sulphamethoxazole and tetracycline. Though still at low levels, the major concern from our findings is the emerging resistance of enteric pathogens that was observed to quinolones (ciprofloxacin, nalidixic acid, norfloxacin) and gentamycin.

scholarly journals Genomic diversity of Escherichia coli isolates from backyard chickens and guinea fowl in the Gambia

2020 ◽  
Author(s):  
Ebenezer Foster-Nyarko ◽  
Nabil-Fareed Alikhan ◽  
Anuradha Ravi ◽  
Nicholas M. Thomson ◽  
Sheikh Jarju ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Resistance ◽  
Guinea Fowl ◽  
Genomic Diversity ◽  
Sub Saharan Africa ◽  
Human Society ◽  
E Coli ◽  
Backyard Poultry ◽  
Link Type ◽  
Sub Saharan

AbstractChickens and guinea fowl are commonly reared in Gambian homes as affordable sources of protein. Using standard microbiological techniques, we obtained 68 caecal isolates of Escherichia coli from ten chickens and nine guinea fowl in rural Gambia. After Illumina whole-genome sequencing, 28 sequence types were detected in the isolates (four of them novel), of which ST155 was the most common (22/68, 32%). These strains span four of the eight main phylogroups of E. coli, with phylogroups B1 and A being most prevalent. Nearly a third of the isolates harboured at least one antimicrobial resistance gene, while most of the ST155 isolates (14/22, 64%) encoded resistance to ≥3 classes of clinically relevant antibiotics, as well as putative virulence factors, suggesting pathogenic potential in humans. Furthermore, hierarchical clustering revealed that several Gambian poultry strains were closely related to isolates from humans. Although the ST155 lineage is common in poultry from Africa and South America, the Gambian ST155 isolates belong to a unique cgMLST cluster comprised of closely related (38-39 alleles differences) isolates from poultry and livestock from sub-Saharan Africa—suggesting that strains can be exchanged between poultry and livestock in this setting. Continued surveillance of E. coli and other potential pathogens in rural backyard poultry from sub-Saharan Africa is warranted.Author notesAll supporting data and protocols have been provided within the article or as supplementary data files. Eleven supplementary figures and eight supplementary files are available with the online version of this article.Data summaryThe genomic assemblies for the isolates reported here are available for download from EnteroBase (http://enterobase.warwick.ac.uk/species/index/ecoli) and the EnteroBase assembly barcodes are provided in File S2.Sequences have been deposited in the NCBI SRA, under the BioProject ID: PRJNA616250 and accession numbers SAMN14485281 to SAMN14485348 (File S2). Assemblies have been deposited in GenBank under the BioProject ID: PRJNA616250 and accession numbers CP053258 and CP053259.Impact statementDomestic birds play a crucial role in human society, in particular contributing to food security in low-income countries. Many households in Sub-Saharan Africa rear free-range chickens and guinea fowl, which are often left to scavenge for feed in and around the family compound, where they are frequently exposed to humans, other animals and the environment. Such proximity between backyard poultry and humans is likely to facilitate transmission of pathogens such as Escherichia coli or antimicrobial resistance between the two host species. Little is known about the population structure of E. coli in rural chickens and guinea fowl, although this information is needed to contextualise the potential risks of transmission of bacterial strains between humans and rural backyard poultry. Thus, we sought to investigate the genomic diversity of E. coli in backyard poultry from rural Gambia.

scholarly journals Drivers of antimicrobial resistance amongst intestinalEscherichia coliisolated from children in South Asia and sub-Saharan Africa

2017 ◽  
Author(s):  
Danielle J. Ingle ◽  
Myron M. Levine ◽  
Karen L. Kotloff ◽  
Kathryn E. Holt ◽  
Roy M. Robins-Browne
Keyword(s):  
Developing Countries ◽  
Antimicrobial Resistance ◽  
South Asia ◽  
Enteric Bacteria ◽  
Sub Saharan Africa ◽  
Fluoroquinolone Resistance ◽  
E Coli ◽  
Antimicrobial Usage ◽  
Sub Saharan ◽  
Usage Data

AbstractAntimicrobial resistance (AMR) dynamics are poorly understood in developing countries, where data on the prevalence of AMR in enteric bacteria are sparse, particularly among children and in the community setting. Here we use a combination of phenotyping, genomics and antimicrobial usage data to investigate patterns of AMR amongst atypical enteropathogenicE. coli(aEPEC) strains isolated from children <5 years old in seven countries (four in sub-Saharan Africa and three in South Asia) over a three-year period. We detected very high rates of AMR, with 65% of isolates displaying resistance to ≥3 drug classes; the rates of AMR were the same amongst strains associated with diarrhea and strains that were carried asymptomatically. Whole genome sequencing identified a diversity of genetic mechanisms for AMR, which could explain >95% of observed phenotypic resistance. Analysis of AMR gene co-occurrence revealed clusters of acquired AMR genes that were frequently co-located on small plasmids and transposons, providing opportunities for acquisition of multidrug resistance in a single step. We used discriminant analysis to investigate potential drivers of AMR within the bacterial population, and found that genetic determinants of AMR were associated with geographical location of isolation but not with phylogenetic lineage of theE. colistrain or disease status of the human host. Comparison with antimicrobial usage data showed that the prevalence of resistance to newer drugs (fluoroquinolones and third-generation cephalosporins) was correlated with usage, which was generally higher in South Asia than Africa. In particular, fluoroquinolone resistance-associated mutations ingyrAwere significantly associated with use of these drugs for treatment of diarrheic children. Notably resistance to older drugs such as trimethoprim, chloramphenicol and ampicillin, which are conferred by acquired AMR genes that were frequently clustered together in mobile genetic elements, were common in all locations despite differences in usage; this suggests that reversion to sensitivity is unlikely to occur even if these drugs are removed from circulation. This study provides much-needed insights into the frequencies of AMR in intestinalE. coliin community-based children in developing countries and to antimicrobial usage for diarrhea where the burden of infections is greatest.

scholarly journals Charcoal and Wood Biomass Utilization in Uganda: The Socioeconomic and Environmental Dynamics and Implications

2020 ◽  
Vol 12 (20) ◽  
pp. 8337
Author(s):  
Dastan Bamwesigye ◽  
Petr Kupec ◽  
Georges Chekuimo ◽  
Jindrich Pavlis ◽  
Obed Asamoah ◽  
...  
Keyword(s):  
Alternative Energy ◽  
Empirical Studies ◽  
Sub Saharan Africa ◽  
Natural Forests ◽  
Fuel Use ◽  
Wood Fuel ◽  
Biomass Utilization ◽  
Qualitative Approaches ◽  
Sub Saharan ◽  
The Government

Charcoal and firewood fuel biomass utilization is thought to be the main cause of deforestation in Uganda. Moreover, the practice of utilizing charcoal and wood fuel in Uganda is said to impact the health of many women and children in the region. The goal of this study was to comprehensively analyze charcoal and wood fuel utilization processes in Uganda and sub-Saharan Africa and the environmental and socioeconomic dynamics and implications. The study equally intended to model out some possible improvements to wood fuel use while conserving natural forests. Both qualitative and qualitative approaches were used to study the charcoal and wood fuel energy situation in Uganda. The study collected field data (sample size: 199) which was subjected to descriptive analysis. The findings show that over 90% of households in Uganda and the sub- Saharan region use firewood and charcoal wood fuel, and that this fuel use creates social and environmental hazards. Our findings are also in agreement with numerous empirical studies showing that firewood and charcoal biomass are among the major causes of deforestation in Uganda and the sub-Saharan region. Ceteris paribus, we propose the adoption of Improved Eco-Stoves (ICE), which not only enable comprehensive combustion but also lessen the quantity of firewood used by more than 60%, together with policy decisions on the government of Uganda, given peoples willingness to take on alternative energy sources such as gas and electricity.

Factors limiting the adoption of hemp as an alternative sustainable material for green building delivery in Ghana

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Kofi Agyekum ◽  
Emmanuel Adinyira ◽  
James Anthony Oppon
Keyword(s):  
Building Materials ◽  
Green Building ◽  
Sub Saharan Africa ◽  
Content Type ◽  
Sustainable Material ◽  
Environmental Threats ◽  
Additional Information ◽  
Comparative Review ◽  
Sub Saharan ◽  
The Government

PurposeThe increased awareness of global environmental threats like climate change has created an upsurge of interest in low embodied carbon building materials for green building delivery. Though the literature advocates for the use of hemp-based building materials, there is no evidence of studies to explore its potential use in Ghana. Therefore, this study explores the potential factors that limit the adoption of hemp as an alternative sustainable material for green building delivery in Ghana.Design/methodology/approachA structured questionnaire was used to solicit the views of built environment professionals operating in construction, consulting and developer firms. The questions were developed through a comparative review of the related literature and complemented with a pilot review. Data were analysed via descriptive and inferential statistics.FindingsOn the average, the majority of the respondents showed a moderate level of awareness of hemp and its related uses in the construction industry. Also, certain key factors like the perceived association of hemp with marijuana, lack of expertise in the production of hemp-related building materials, farmers not getting the needed clearance for the cultivation of hemp, lack of legislation by the government in the legalisation of hemp and the inadequate knowledge of consumers on the benefits of hemp-based building materials were identified as potential limitations to the adoption of hemp as an alternative sustainable material for green building delivery.Originality/valueThe findings from this study provide insights into a less investigated area in sub-Saharan Africa and further provide new and additional information to the current state-of-the-art on the potential for the use of hemp in the building construction sector.

scholarly journals #RESISTHUDUMANAMBA: KENYAN GOVERNMENT AT A CROSSROAD

2019 ◽  
Vol 2019 ◽  
Author(s):  
Job Mwaura
Keyword(s):  
Identity Management ◽  
Digital Technologies ◽  
Study Data ◽  
Sub Saharan Africa ◽  
Biometric Data ◽  
Qualitative Research Study ◽  
Online Spaces ◽  
Identity Management System ◽  
Sub Saharan ◽  
The Government

In the past few years, Kenya’s digital landscape has transformed and this has been made possible by proliferation of the usage of digital technologies, particularly - mobile phones. Due to increased access to digital technologies, faster internet speeds, increased securitization among other issues, data on individuals in online spaces has also increased. Recently, the government rolled out a National Integrated Identity Management System (NIIMS) which is meant to capture biometric data but this has generated a huge debate online in Kenya under the hashtag #ResistHudumaNamba. This paper will therefore examine the following issues: What has contributed to the decline of trust between the government and its citizens when it comes to internet technologies? What are the actual sentiments given for and against in the introduction of Huduma Number? What are the underlying reasons for continued registration of individuals in Kenya? This research will be a qualitative research study. Data will be generated from social media sites (Twitter and Facebook), as well as blog posts and newspaper articles. A discourse analysis of the events around #ResistsHudumaNamba in these sources will be done so as to answer the research questions. This research has the potential to contribute to literature on trust in sub-Saharan Africa as well as establish trust issues between government and citizens when digital technologies are involved.

scholarly journals Factors That Matter for Financial Inclusion: Evidence from Sub-Sharan Africa - The Zimbabwe Case

2021 ◽  
Vol 10 (6) ◽  
pp. 48
Author(s):  
David Mhlanga
Keyword(s):  
Smallholder Farmers ◽  
Multinomial Logistic Regression ◽  
Multinomial Logit Model ◽  
Financial Inclusion ◽  
Sub Saharan Africa ◽  
Farm Income ◽  
Smallholder Farming ◽  
Hand Off ◽  
Sub Saharan ◽  
The Government

The study intended to investigate the factors that are important in influencing the financial inclusion of smallholder farming households in Sub-Saharan Africa with a specific focus on Zimbabwe. Motivated by the fact that there is an increase in the evidence of the importance of financial inclusion in fighting poverty and the fact that by merely having a bank account, financial inclusion cannot be guaranteed, the study went further to interrogate factors that influence smallholder farmers to have a transaction account, to borrow and to have insurance. Since the dependent variable of financial inclusion had more than two categories, with three unordered categories, transaction account, savings/credit account, and insurance, the multinomial logistic regression was used to estimate the determinants of financial inclusion from these three categories of the dependent variable. The multinomial logit model results, with insurance as the reference category, indicated that the size of the household, transaction costs, gender and agricultural extension service were the factors influencing the demand for a household to open a transaction account. On the other hand, off-farm income and age of the household were the only two factors significantly influencing households to borrow. Therefore, it is imperative for, the government of Zimbabwe to come up with more policies that encourage farmers to participate in the formal financial market as financial inclusion can help to fight poverty and the general developments of societies.   Received: 28 April 2021 / Accepted: 31 August 2021 / Published: 5 November 2021

scholarly journals Towards Pragmatic Economic Policies: Economic Transformation and Industrialization for Revival of Zimbabwe in the New Dispensation Era

2020 ◽  
Vol 10 (5) ◽  
pp. 75-81
Author(s):  
Charles Mazhazhate ◽  
Tapiwa C Mujakachi ◽  
Shakerod Munuhwa
Keyword(s):  
Economic History ◽  
Land Reform ◽  
Economic Transformation ◽  
Sub Saharan Africa ◽  
Economic Policies ◽  
Consumer Prices ◽  
Before And After ◽  
Sub Saharan ◽  
The Government ◽  
Economic Institute

Whilst literature has many monetary and economic policies that were enacted before and after the dawn of the New Dispensation in Zimbabwe the country still faces a downward trend in terms of economic recovery. This study reviews the various policies put in place by the government and their impact on socio-economic development of Zimbabwe. A review of Zimbabwe’s economic history shows that the country dropped from being one of the best economies in Sub-Saharan Africa and now ailing and characterised by hyperinflation, agricultural challenges, corruption, very high tax regime, huge domestic and foreign debts, increase in consumer prices and being a chief net importer of most goods or services. The study was underpinned by a case study survey from Singapore’s revival with both qualitative and quantitative instruments used. The study found out that even though the land reform had an impact on economic performance, corruption, party-power politics and absence of an economic institute eroded any necessary contribution to economic transformation and industrialization in Zimbabwe. The study also revealed that the bilateral and multi-lateral agreements that were enacted in the dawn of the new dispensation have not yielded the desired economic revival transformations. The study recommended establishment of an economic institute to direct policy as well as removal of unethical practices in both public and private sectors so as to ensure financial and economic discipline.

scholarly journals Vaccine Hesitancy: In the Age of the COVID-19 Pandemic

2021 ◽  
pp. 9-16
Author(s):  
Mohammad Jahidur Rahman Khan ◽  
Samshad Jahan Shumu ◽  
Farzana Mim ◽  
Md. Selim Reza
Keyword(s):  
Modern Science ◽  
Sub Saharan Africa ◽  
Vaccine Hesitancy ◽  
Healthcare Personnel ◽  
Common Causes ◽  
Vaccination Acceptance ◽  
Worldwide Phenomenon ◽  
Sub Saharan ◽  
The Government ◽  
Acceptance Rates

Vaccines are one of the most significant innovations of modern science. Worldwide, millions of lives are saved each year by the vaccine. Vaccine hesitancy, which represents the refusal to receive vaccines when vaccination services are available and reachable, is a major obstacle to global health. While vaccine hesitancy has been present for many years, its damaging effects are likely to be more evident during the COVID-19 pandemic than ever before. This study aimed to find out common causes of vaccine hesitancy, assess COVID-19 vaccination acceptance rates worldwide, and present the approaches by which vaccine hesitancy rate can be reduced. This study revealed though vaccine hesitancy is a worldwide phenomenon, the causes differ from country to country or reign. More studies are needed to address COVID-19 vaccine hesitancy, especially in the Middle and South America, the Middle East and North Africa, Central Asia, Sub-Saharan Africa, Eastern Europe. The leading causes of COVID-19 vaccine hesitancy are found lack of confidence towards the government or pharmaceutical companies, less concern about the outcome of SARS-CoV-2 infection, and shortage of supply of different types of COVID-19 vaccines. Healthcare personnel and social media play an essential role in addressing vaccine hesitancy. Convincing the general population about the safety and effectiveness of COVID-19 vaccines, the consequence of being unvaccinated, and the delivery of free vaccines in an easily accessible way can reduce vaccine hesitancy rate.

scholarly journals THE ROLE OF WOMEN EMPOWERMENT IN AGRICULTURE ON HOUSEHOLD FARM COMMERCIALIZATION OF MAIZE, POTATOES AND BEANS IN NORTHERN PROVINCE OF RWANDA

2021 ◽  
Vol 59 (1) ◽  
Author(s):  
Olive Uwineza ◽  
Job Lagat ◽  
Risper M Berem
Keyword(s):  
Negative Relationship ◽  
Women's Empowerment ◽  
Sub Saharan Africa ◽  
Women’S Empowerment ◽  
Farm Size ◽  
Northern Province ◽  
Sub Saharan ◽  
The Government ◽  
Women's Role ◽  
Agriculture And Food

In Sub-Saharan Africa, agricultural commercialization is a major factor in household food diversification and household income. To move to agricultural transformation, Rwanda has focused on shifting from subsistence-based farming to market-oriented agriculture. Various studies have been conducted on agricultural commercialization, however, women’s role in the commercialization of agriculture has received little attention and none of the studies have associated it with women’s empowerment in agriculture. In Rwanda, women are principal players in agriculture and food security, therefore, it is important to understand the influence of their empowerment in agriculture on its commercialization. To investigate the relationship between women’s empowerment in agriculture and agricultural commercialization, the Women’s Empowerment in Agriculture Index (WEAI) was used to measure women’s empowerment in agriculture. A sample size of 252 households from Musanze and Burera districts in the Northern Province of Rwanda was used. It was obtained using the multistage and random sampling techniques. To analyze data, a fractional regression model was used. The results revealed that farm commercialization in Rwanda was positively and significantly influenced by WEAI score, farm size and the prices of maize, potatoes and beans. On the other hand, the index has a negative relationship with access to extension services. It is recommended that the government should strengthen policies of empowering women in agriculture.

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