Application of 3D-Printed Personalized Guide in Arthroscopic Ankle Arthrodesis

Objective. To accurately drill the Kirschner wire with the help of the 3D-printed personalized guide and to evaluate the feasibility of the 3D technology as well as the outcome of the surgery. Methods. Patients’ DICM data of ankle via CT examinations were introduced into the MIMICS software to design the personalized guides. Two 2mm Kirschner wires were drilled with the help of the guides; the C-arm fluoroscopy was used to confirm the position of the wires before applying the cannulated screws. The patients who underwent ankle arthrodesis were divided into two groups. The experimental group adopted the 3D-printed personalized guides, while the control group received traditional method, i.e., drilling the Kirschner wires according to the surgeon’s previous experience. The times of completing drilling the Kirschner wires to correct position were compared between the two groups. Regular follow-ups were conducted to statistically analyze the differences in the ankle fusion time and AOFAS scores between the two groups. Results. 3D-printed personalized guides were successfully prepared. A total of 29 patients were enrolled, 15 in the experimental group and 14 in the control group. It took 2.2 ± 0.8 minutes to drill the Kirschner wires to correct position in the experimental group and 4.5 ± 1.6 minutes in the control group (p=0.001). No obvious complications occurred in the two groups during and after surgery. Postoperative radiographs confirmed bony fusion in all cases. There were no significant differences in the fusion time (p=0.82) and AOFAS scores at 1 year postoperatively between the two groups (p=0.55). Conclusions. The application of 3D-printed personalized guide in assisting the accurate drilling of Kirschner wire in ankle arthrodesis can shorten the operation time and reduce the intraoperative radiation. This technique does not affect the surgical outcome. Trial Registration Number. This study is registered on www.clinicaltrials.gov with NCT03626935.

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Clinical Application of a 3D-Printed Positioning Module and Navigation Template for Percutaneous Vertebroplasty

Surgical Innovation ◽

10.1177/15533506211062404 ◽

2021 ◽

pp. 155335062110624

Author(s):

Jing Yang ◽

Penghui Ni ◽

Lina Zhang ◽

Zhanxin Lu ◽

Dapeng Liu ◽

...

Keyword(s):

Percutaneous Vertebroplasty ◽

Operation Time ◽

Vertebral Compression Fractures ◽

Control Group ◽

Compression Fractures ◽

Intraoperative Fluoroscopy ◽

3D Printed ◽

Vas Scores ◽

Experimental Group ◽

Navigation Template

Background This study aimed to evaluate a personalized 3D-printed percutaneous vertebroplasty positioning module and navigation template based on preoperative CT scan data that was designed to treat patients with vertebral compression fractures caused by osteoporosis. Methods A total of 22 patients with vertebral compression fractures admitted to our hospital were included in the study. Positioning was performed with the new 3D-printed positioning module, and the navigation template was used for patients in the experimental group, and the traditional perspective method was used for patients in the control group. The experimental group consisted of 11 patients, 2 males and 9 females, with a mean age of 67.27 ± 11.86 years (range: 48 to 80 years), and the control group consisted of 11 patients, 3 males and 8 females, with a mean age of 74.27 ± 7.24 years (range: 63 to 89 years). The puncture positioning duration, number of intraoperative fluoroscopy sessions, and preoperative and postoperative visual analog scale (VAS) scores were statistically analyzed in both groups. Results The experimental group had shorter puncture positioning durations and fewer intraoperative fluoroscopy sessions than the control group, and the differences were statistically significant (P < .05). There were no significant differences in age or preoperative or postoperative VAS scores between the two groups (P > .05). Conclusions The new 3D-printed vertebroplasty positioning module and navigation template shortened the operation time and reduced the number of intraoperative fluoroscopy sessions. It also reduced the difficulty in performing percutaneous vertebroplasty and influenced the learning curve of senior doctors learning this operation to a certain degree.

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Effect of 3D-Printed Hearts Used in Left Ventricular Outflow Tract Obstruction: A Multicenter Study

10.21203/rs.3.rs-1206928/v1 ◽

2022 ◽

Author(s):

Xianzhi Wang ◽

Jixiang Liang ◽

Cunfu Mu ◽

Wenlin Zhang ◽

Chunzhu Xue ◽

...

Keyword(s):

Left Ventricular Outflow Tract ◽

Operation Time ◽

Ventricular Outflow Tract ◽

Left Ventricular ◽

Outflow Tract ◽

Control Group ◽

Intraoperative Blood Loss ◽

Left Ventricular Outflow ◽

3D Printed ◽

Experimental Group

Abstract Objective:The purpose of this research was to explore the application value of a three-dimensional (3D)-printed heart in the operation for left ventricular outflow tract (LVOT) obstruction. Methods: From August 2019 to October 2021, 46 patients with LVOT obstruction underwent surgical treatment at Peking University International Hospital, Southwest Medical University Affiliated Hospital of Traditional Chinese Medicine and Guangyuan First People's Hospital. According to the treatment method, 22 cases were allocated to the experimental group and 24 cases to the control group . The operation time, cardiopulmonary bypass time, intraoperative blood loss, hospitalization time, postoperative ejection fraction (EF), left ventricular flow velocity (LVFV), LVOT pressure difference (LVP), postoperative interventricular septal thickness (IST), inner diameter of the left ventricular outflow tract (IDLV), systolic anterior motion (SAM), atrioventricular block rate, aortic regurgitation (AR) rate and surgical complication rate of the two groups were compared. Results: The operation time, cardiopulmonary bypass time, intraoperative blood loss, hospitalization time, LVP, postoperative IST, AR, SAM, and postoperative LVFV of the experimental group were significantly lower than those of the control group (P < 0.05). The IDLV was larger than that of the control group (P < 0.05). There was no significant difference in the postoperative EF, atrioventricular block rate or complication rate between the two groups (P > 0.05). Conclusion: A 3D-printed heart model for in vitro simulation surgery is conducive to formulating a more reasonable surgical plan and reducing surgical trauma and operation time, thereby promoting the recovery and maintenance of the heart.

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Application of Three-dimensional Visualization assisted Ultrasound for Percutaneous Renal Puncture

10.21203/rs.3.rs-113148/v1 ◽

2020 ◽

Author(s):

Zhibin Xu ◽

Zhenchi Li ◽

Maomao Guo ◽

Hao Bian ◽

Tianli Niu ◽

...

Keyword(s):

Clearance Rate ◽

3D Visualization ◽

Three Dimensional ◽

Operation Time ◽

Control Group ◽

Transfusion Rate ◽

Stone Clearance ◽

Time Operation ◽

Postoperative Blood Transfusion ◽

Experimental Group

Abstract We present here the three-dimensional (3D) visualization fused with ultrasound and to evaluate its clinical application effect preliminarily. One hundred and eighteen patients with renal calculi in our hospital from September 2017 to December 2019 were prospectively randomized into two groups. The experimental group was treated with percutaneous renal puncture guided by the 3D visualization fused with ultrasound. The control group was treated with percutaneous renal puncture guided by B-ultrasonography (B-US). The puncture time, operation time, and the loss of hemoglobin in the experimental group were lower than those in the control group, and the success rate of establishing the channel at one time, and the coincidence rate between the channel and the longitudinal axis of the target renal calyx were higher. The stone clearance rate in the experimental group was higher, while the postoperative blood transfusion rate and interventional embolization rate in the experimental group were significantly lower. The difference was statistically significant (P < 0.05). 3D visualization assisted ultrasound could preliminarily guide precise navigation to puncture tissues, reduced operation time and bleeding, improved stone clearance rate and operation safety.

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A Novel Device for Accurate Guide wire Placement in Cannulated Screw Fixation of Femoral Neck Fracture:A Pilot Study

10.21203/rs.3.rs-57323/v1 ◽

2020 ◽

Author(s):

bu-fang ren ◽

quan-ping Ma ◽

xin lv

Keyword(s):

Femoral Neck ◽

Femoral Neck Fracture ◽

Screw Fixation ◽

Kirschner Wire ◽

Operation Time ◽

Conventional Technique ◽

Novel Device ◽

Neck Fracture ◽

Guide Device ◽

Experimental Group

Abstract Background: Accurate placement of cannulated screws is the key to stable fixation of the femoral neck fracture. A novel device was developed to improve the accuracy of screw placement.Methods: 20 synthetic femoral bones were divided into conventional technique group and the experimental group. Three Kirschner wire were inserted into the femoral neck fracture by conventional technique or by the simple guide device. The operative time, total drilling times and fluoroscopic frequency were evaluated.Results: By using the guide device, the fluoroscopy and operation time of the experimental group were shorter that of the conventional method. The total drilling times with the simple guide device were significantly lower than the conventional technique group.Conclusions: This device can help trauma surgeons shorten the surgical time and reduce radiation exposure time. The use of this guide device can make screw fixation for femoral neck fracture easier.

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Study on the Effect of Removing the Slide Wire Screw on Locking Plate by Nail Groove Reconstruction Method

10.21203/rs.3.rs-1121716/v1 ◽

2021 ◽

Author(s):

Guanglei Zheng ◽

Yingjie Qi

Keyword(s):

Blood Loss ◽

Locking Plate ◽

Operation Time ◽

Healing Time ◽

Control Group ◽

Reconstruction Method ◽

Intraoperative Blood Loss ◽

Limb Function ◽

Experimental Group ◽

Tungsten Steel

Abstract Background: This paper is to describe and evaluate the nail groove reconstruction method in removing slide wire screw on locking plate. Then compare the method with tungsten steel drilling nail method, to explore a new method of removing slide wire screw on locking plate.Method: A total of 1254 patients with removal fracture internal fixation devices were collected from the Affiliated Hospital of Hangzhou Normal University from July 2015 to September 2021, of which 62 cases met the inclusion and exclusion criteria. All patients were randomly divided into the experimental group and the control group. 31 people per group. There were 19 males and 12 females in the experimental group, the age of patients was 35.68±11.70years; while 18 males and 13 females in the control group, the age of patients was 36.27±10.37years. Nail groove reconstruction method was used in the experimental group, and the tungsten steel drilling nail method was used in the control group. Collect and count surgical-related indicators, the data of two groups were compared and analyzed from four aspects: intraoperative blood loss, operation time, incision healing time and limb function recovery time.Result: All slide wire screws were removed successfully, and all patients had no serious postoperative complications such as internal fixation retention and neurovascular injury. The experimental group was better than the control group in the following three aspects: the amount of intraoperative blood loss, the operative time, the recovery time of limb function, and the differences were statistically significant(p < 0.05). There was no significant difference in incision healing time between the two groups.Conclusion: The nail groove reconstruction method has less damage to the bone and soft tissue, less intraoperative blood loss, shorter operation time, and faster postoperative recovery of limb function. The nail groove reconstruction method is a simple and effective method, it has obvious advantages compared with the traditional method.

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The Guiding Effect of Digital Image Based on Cone-Beam Computed Tomographic on Oval Root Canal Preparation

10.21203/rs.3.rs-747864/v1 ◽

2021 ◽

Author(s):

Yiwei Wang ◽

Wenjun Xia ◽

Zisheng Tang ◽

Yan Zou ◽

Xiaohe Bian ◽

...

Keyword(s):

Digital Image ◽

Root Canal ◽

Cone Beam ◽

Control Group ◽

Root Canal Preparation ◽

Computed Tomographic ◽

Significant Difference ◽

3D Printed ◽

Experimental Group ◽

Guiding Effect

Abstract Background: To evaluate the guiding effect of digital image based on cone-beam computed tomographic in improving the quality of single oval root canal preparation.Methods: A premolar was selected by CBCT and a 3D-printed root canal model was made. Twenty postgraduates from the Department of Stomatology of Shanghai Ninth People's Hospital were selected to perform root canal preparation on 3D printed oval root canal model teeth. They were randomly assigned to two groups(n=10) according to the guiding method received: CBCT original image (control group) and CBCT-based digital image (experimental group). CBCT scans were performed on the models before and after the guidance. The changes in root canal cleanliness, residual minimum thickness, transportation and over-preparation amount were analyzed.Results: The experimental group caused significantly more increased amount of cleanliness compared to control group(P<0.05)：6.0373% ±6.0766% in the control group and 13.7193%±6.7102% in the experimental group. There was no significant difference in the reduction of residual minimum wall thickness between the two groups (P>0.05)： 0.0154mm±0.2110mm in the control group and 0.0362±0.0444mm in the experimental group. In the control group, the transportation after second preparation was generally increased (increased 0.0084mm on average). In the experimental group, the transportation was generally reduced after second preparation (reduced 0.0081mm on average). But there was no significant difference in the transportation change between the two groups (P>0.05). After the second preparation, there was no significant difference in the amount of increased over-preparation between the two groups（P＞0.05）: 1.7029%±3.6622% in the control group and 3.5144%±4.8075% in the experimental group.Conclusions: Compared with traditional CBCT image guidance, the digital image method can significantly improve the cleaning effect of the oval root canal preparation. It didn’t result in more over-preparation and the amount of residual wall thickness was ensured. At the same time, it has a certain effect on reducing transportation after the guidance.

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Research on the Application of PBL Teaching Method in Physics Experiment Teaching

Global Journal of Human-Social Science ◽

10.34257/gjhssgvol21is10pg53 ◽

2021 ◽

pp. 53-56

Author(s):

Qi Tian ◽

Zhi-Xin Huang ◽

Wei Li ◽

Ming-Hai Wu ◽

Yu-Jie Chen

Keyword(s):

High School ◽

Junior High School ◽

Junior High ◽

Teaching Method ◽

Control Group ◽

Traditional Teaching ◽

The Times ◽

Physics Experiment ◽

Experimental Group ◽

Better Than

Discuss the method and effect of problem-based teaching method (PBL) in the teaching of physics experiment in junior high school. Method: A total of 92 students in two junior high school classes were selected, and one of them was randomly set as the experimental group (46 students) and the other one was the control group (456 students). The experimental group added PBL teaching on the basis of traditional teaching methods. Methods, the control group was taught according to the traditional teaching method only, and finally the teaching effect of the two groups was compared. Results: The physics performance of the experimental group was significantly higher than that of the traditional teaching group (P<0.05). The students in the experimental group were better than traditional teaching in subjective evaluations such as learning initiative, learning interest, thinking ability training, practical ability, and innovation ability. Conclusion: The PBL teaching model is more adapted to the development of the times, and the effect is better than traditional teaching. It can combine the learning and practical skills of students, and the comprehensive ability can be greatly improved.

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The Effect of Kryptonite Bone Cement combined with a Standard Kirschner Wire on Tibial Bone Fracture in Rats

International Journal Of Medical Science And Clinical Invention ◽

10.18535/ijmsci/v9i01.04 ◽

2022 ◽

Vol 9 (01) ◽

pp. 5808-5913

Author(s):

Ibrahim EKE ◽

Mehmet Akif AKCAL ◽

Yusuf IYETIN ◽

OguzSükrü POYANLI

Keyword(s):

Bone Cement ◽

Bone Repair ◽

Callus Formation ◽

Statistical Significance ◽

Kirschner Wire ◽

Autogenous Bone ◽

Control Group ◽

Complete Fusion ◽

Non Union ◽

Experimental Group

Objective This study aims to observe whether Kryptonite Bone Cement combined with a standard Kirschner wire, instead of autogenous bone grafts, increases bone healing and mechanical strength in rats with tibia fractures. Methods The study included sixteen rats, which were divided into two groups as a control group (n=8) and an experimental group (n=8). After segmental fractures were made in both groups, intramedullary fixation of tibia procedures were conducted with the use of a Kirschner wire. No additional procedures were performed inthe control group, but Kryptonite Bone Cement was applied in the experimental group. The rats were evaluated clinically, radiologically and histologically4 times; immediately after the operation, and atthe 1st, 3rd, and 6thweeks following surgery. Results One rat from the experimental and one from the control group had both wound dehiscence and wound site infection. No recovery was observed in any rats either in the control or experimental group immediately after surgery. During week 1, callus formation was identified in 5 rats in the experimental group (p=0.0072), and during week 3, fracture lines disappeared in 4 rats in the experimental group (p=0.064); the differences between control and experimental groups were statistically significant. During week 6, no statistical significance was observed in radiological assessments for the control group and experimental group (p=0.71). The rate of non-union was higher in the control group (37.50%) than in the experimental one, while the rate of complete fusion was higher in the experimental group (87.50%) than that in the control group. Conclusion Osteoconductivity and ergonomic qualities of Kryptonite Bone Cement prove helpful in bone repair. Future studies to be conducted in a prospective and randomized manner will be effective on demonstrating the effectiveness of Kryptonite Bone Cement.

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Voice Initiation and Termination Times in Stuttering and Nonstuttering Children

Journal of Speech Language and Hearing Research ◽

10.1044/jshr.2302.344 ◽

1980 ◽

Vol 23 (2) ◽

pp. 344-360 ◽

Cited By ~ 28

Author(s):

Walter L. Cullinan ◽

Mark T. Springer

Keyword(s):

Pure Tone ◽

Response Times ◽

Auditory Signal ◽

Control Group ◽

Communication Disorder ◽

Language Problem ◽

Language Problems ◽

The Times ◽

Experimental Group ◽

Normal Speaking

The times needed to initiate and terminate voicing in response to series of short segments of 1000 Hz pure-tone auditory signal were studied for stuttering and nonstuttering children. The effects of random reward and nonreward on the phonatory response times also were studied. The experimental group consisted of 20 children, 11 of whom had other speech and/or language problems in addition to stuttering and nine whose only communication disorder was stuttering. The control group consisted of 20 normal-speaking children balanced with the stuttering group for sex and age. Children with speech and/or language problems in addition to stuttering were found to have significantly slower voice initiation and termination times than the normal-speaking children. The children with stuttering as the only speech and/or language problem generally did not differ significantly from the normal-speaking children in phonation times. The data suggest that whereas older stuttering children have longer phonation times than do nonstuttering children, younger stuttering children do not. Voicing times for responses following nonrewarded responses tended to be shorter than those for responses following rewarded responses for both groups.

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Neoadjuvant chemotherapy combined with radical surgery for stage IB2/IIA2 cervical squamous cell carcinoma: a prospective, randomized controlled study of 35 patients

World Journal of Surgical Oncology ◽

10.1186/s12957-021-02318-y ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Huang Jing ◽

Wu Xiuhong ◽

Yu Ying ◽

Liao Zhenrong ◽

Cheng Xiyun ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Neoadjuvant Chemotherapy ◽

Cell Carcinoma ◽

Squamous Cell ◽

Radical Surgery ◽

Disease Free Survival ◽

Operation Time ◽

Cervical Squamous Cell Carcinoma ◽

Control Group ◽

Experimental Group

Abstract Objective This study aimed to evaluate the clinical outcomes for patients with stage IB2/IIA2 cervical squamous cell carcinoma treated with neoadjuvant chemotherapy combined with radical surgery. Methods A total of 68 patients with cervical squamous cell carcinoma were randomly divided into the experimental group (n = 35) and the control group (n = 33). The patients in the experimental group received paclitaxel plus cisplatin neoadjuvant chemotherapy for two cycles, then underwent radical hysterectomy and bilateral adnexectomy at 2 weeks post-chemotherapy. The control group only underwent radical hysterectomy and bilateral adnexectomy after the diagnosis of cervical squamous cell carcinoma. The toxic and side effects of chemotherapy in the experimental group were observed. Also, the operation method, operation time, blood loss, grade of wound healing, complications, and postoperative pathology were noted in the two groups. Primary foci and pelvic lymph node recurrence and distant metastasis were observed, and 3-year and 5-year survival rates were calculated. Results Only one patient in the experiment had grade III bone marrow suppression; no other grade III and IV chemotherapy toxic reactions were observed. The operation was successfully completed in all patients. The operation time, intraoperative blood loss, placement of the ureteral catheter, bladder injury, ureteric injury, postoperative urinary tub, pelvic drainage tube indwelling time, anal exhaust time, postoperative complications, and metastatic ratio of lymph nodes were not significantly different between the two groups (P > 0.05). The number of dissected lymph nodes, deep myometrial invasion, and vascular tumor emboli showed a significant difference in the experimental group compared with the control group (P < 0.05). The 3-year disease-free survival (82.9% vs 81.9%), 5-year disease-free survival (71.4% vs 60.6%), 3-year overall survival (91.4% vs 87.8%), and 5-year overall survival (82.9% vs 75.6%) were not statistically significantly different between the experimental group and the control group (P > 0.05). Conclusions Neoadjuvant chemotherapy in IB2/IIA2 stage cervical squamous cell carcinoma showed low toxic side effects. Radical surgery after chemotherapy is safe and feasible. It plays a coordinating role in reducing the tumor infiltration depth of the deep muscle layer and the incidence of vascular tumor emboli, reducing the use of postoperative adjuvant therapy, and improving the quality of life of patients, but does not improve the 3-year/5-year survival rate.

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