Importance of Mechanical Periodontal Therapy in Patients with Diabetes Type 2 and Periodontitis

Periodontitis is an infectious and inflammatory disease of high prevalence worldwide and constitutes a significant oral health problem. It can lead to tooth loss. In addition, the local inflammatory process can cause the release of inflammatory mediators in the bloodstream and, consequently, contribute to the emergence of systemic effects as cardiovascular and diabetic complications. The purpose of this mini review is to alert health professionals about the risk that periodontitis represents for the onset or exacerbation of complications in individuals with type 2 diabetes mellitus and to emphasize that the mechanical treatment of periodontal disease and reestablishment of oral health are essential for the metabolic control of these patients. The periodontal therapy may help to reduce the risk of systemic complications in diabetes patients. Proper dental management should be suggested by health professionals, mainly from physicians to their patients, in order to improve the health conditions in these individuals.

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Risk Factors Associated With Hyperuricemia in Patients with Diabetes Type 2: About 190 Cases

10.36502/2020/droa.6163 ◽

2020 ◽

Vol 2 (1) ◽

pp. 12-16

Author(s):

Fennoun H ◽

Haraj NE ◽

El Aziz S ◽

Bensbaa S ◽

Chadli A

Keyword(s):

Type 2 Diabetes ◽

Heart Disease ◽

Glycemic Control ◽

Ischemic Heart Disease ◽

Diabetes Type 2 ◽

Diabetes Type ◽

Ischemic Heart ◽

Factors Associated ◽

Patients With Diabetes

Introduction: Hyperuricemia is common Type 2 diabetes at very high cardiovascular risk. Objective: Evaluate the relationship between hyperuricemia and diabetes type 2, and determine its predictive factors in this population. Patients and Methods: Retrospective study cross including 190 patients with diabetes type 2 hospitalized Service of Endocrinology of CHU Ibn Rushd Casablanca from January 2015 to December 2017. Hyperuricemia was defined as a serum uric acid concentration> 70 mg/L (men) and> 60 mg/L (women). The variables studied were the anthropometric measurements), cardiovascular factors (tobacco, hypertension, dyslipidemia), and degenerative complications (retinopathy, neuropathy, kidney failure, ischemic heart disease). The analyzes were performed by SPSS software. Results: Hyperuricemia was found in 26.5% of patients with a female predominance (76%), an average age of 55.9 years, and an average age of 12.4ans diabetes. The glycemic control was found in 84.6% of cases with mean glycated hemoglobin 8.6%. Factors associated al hyperuricemia were the blood pressure in 86% (p <0.05), dyslipidemia in 76.3% of cases (p <0.001) with hypertriglyceridemia in 48.3% of cases (p <0.02), and a hypoHDLémie 28% (p <0.001). The age, obesity, smoking, and glycemic control were associated significantly n al hyperuricemia. The research of degenerative complications of hyperuricemia has objectified renal impairment (GFR between 15 and 60ml / min) chez47% (p <0.001), it was kind of moderate in 35.8% (p <0.01) and severe in 5.1% (p <0.02), ischemic heart disease was found in 34% of cases (p <0.01). Conclusion: In our study, hyperuricemia in type 2 diabetes is common in female patients, especially with hypertension, dyslipidemia, and renal failure. Other factors such as age, obesity, smoking is not associated with hyperuricemia in type 2 diabetics.

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Initial increase in glucose variability during Ramadan fasting in non-insulin-treated patients with diabetes type 2 using continuous glucose monitoring

Libyan Journal of Medicine ◽

10.1080/19932820.2018.1535747 ◽

2018 ◽

Vol 14 (1) ◽

pp. 1535747 ◽

Cited By ~ 3

Author(s):

Nesreen Aldawi ◽

Gassan Darwiche ◽

Salah Abusnana ◽

Murtada Elbagir ◽

Targ Elgzyri

Keyword(s):

Continuous Glucose Monitoring ◽

Glucose Monitoring ◽

Diabetes Type 2 ◽

Glucose Variability ◽

Diabetes Type ◽

Initial Increase ◽

Ramadan Fasting ◽

Patients With Diabetes

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The specific treatment of dyslipidemia in patients with diabetes type 2

Medical Council ◽

10.21518/2079-701x-2016-3-48-53 ◽

2016 ◽

pp. 48-53 ◽

Cited By ~ 2

Author(s):

S. A. Urazgildeeva ◽

O. F. Malygina

Keyword(s):

Specific Treatment ◽

Diabetes Type 2 ◽

Diabetes Type ◽

Patients With Diabetes

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Physiological features of leptin in patients with diabetes type 2 and eating disorders

Experimental and Clinical Physiology and Biochemistry ◽

10.25040/ecpb2020.03-04.020 ◽

2020 ◽

Vol 2020 (3) ◽

Keyword(s):

Eating Disorders ◽

Diabetes Type 2 ◽

Diabetes Type ◽

Patients With Diabetes

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The Effects of Combined Insulin and Metformin Therapy in Obese Patients with Diabetes Mellits Type 2 in the Early Stage of the Disease

Bosnian Journal of Basic Medical Sciences ◽

10.17305/bjbms.2006.3173 ◽

2006 ◽

Vol 6 (2) ◽

pp. 54-58

Author(s):

Belma Aščić - Buturović

Keyword(s):

Insulin Therapy ◽

Pancreatic Beta Cells ◽

Early Stage ◽

Diabetes Type 2 ◽

Diabetes Type ◽

Target Cells ◽

Obese Patients ◽

Patients With Diabetes ◽

Insulin Activity

Combination of insulin and metformin has been shown to improve glycaemic control in clinical trials, particularly in obese patients with diabetes type 2. Insulin therapy can improve function of pancreatic beta cells and periphery insulin activity in target cells in order to enhance glycaemic homeostasis (1, 2, 3). In our study we included obese patients with diabetes type 2 in the early stage of the disease. The study is partially retrospective and partially prospective. The study encompassed 40 patients split in two groups. The first group of 20 patients received insulin therapy combined with metformin, while the patients of the second group were treated with oral antidiabetic drugs, sulfonylureas and metformin. Three months later, the group treated with insulin and metformin showed improvement in the monitored parameters, namely significant reduction in HbA1c (p = 0.003), MFBG (p = 0.0009), PPG (p = 0.028). Insulin therapy administered together with metformin, in obese patients with diabetes type 2, in the early stage of the disease, resulted in well regulated fasting blood glycaemia, as well as post challenge glycaemia and HbA1c.

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