scholarly journals Albizia Adianthifolia: Botany, Medicinal Uses, Phytochemistry, and Pharmacological Properties

2018 ◽  
Vol 2018 ◽  
pp. 1-18 ◽  
Author(s):  
Alfred Maroyi

The bark, leaves, and roots ofAlbizia adianthifoliaare highly sought after in tropical Africa as herbal medicines. Therefore, the aim of this study was to review the botany, medicinal uses, phytochemistry, and pharmacological properties ofA. adianthifoliaso as to provide baseline data required for evaluating the therapeutic potential of the species. Information on the botanical profile, medicinal uses, phytochemistry, and pharmacological properties ofA. adianthifoliawas undertaken using databases such as ScienceDirect, SciFinder, Pubmed, Google Scholar, Medline, SCOPUS, EThOS, ProQuest, OATD, and Open-thesis. Preelectronic literature search of conference papers, scientific articles, books, book chapters, dissertations, and theses was carried out at the University library. Literature search revealed thatA. adianthifoliais used as purgative and herbal medicine for diabetes, eye problems, gastrointestinal problems, haemorrhoids, headache, neurodegenerative disorders, reproductive problems in women, respiratory problems, wounds and pain, skin diseases, sexually transmitted infections, and ethnoveterinary medicine. Phytochemical compounds identified from the species include apocarotenoids, chalcone, dipeptide, elliptosides, essential oils, fatty acids, flavonoids, histamine, imidazolyl carboxylic acid, prosapogenins, steroids, triterpene saponins, and triterpenoids. Pharmacological studies revealed thatA. adianthifoliaextracts and compounds have acetylcholinesterase enzyme inhibitory, anthelmintic, antiamoebic, antibacterial, antimycobacterial, anti-sexually transmitted infections, antifungal, anti-inflammatory, antioxidant, anxiolytic, and antidepressant, cognitive-enhancing, haemolytic, hypoglycemic and antihyperglycemic, immunomodulatory, and cytotoxicity activities. Detailed studies on the pharmacokinetics, in vivo,and clinical research involving compounds isolated fromA. adianthifoliaand extracts of the species are required.

Author(s):  
Alfred Maroyi

Lannea acida is widely used as herbal medicine in West Africa. The present study critically reviewed the medicinal uses and phytochemistry and pharmacological properties of L. acida. The keywords including L. acida, its synonyms, English common names, medicinal uses, and phytochemistry and pharmacological properties of the species were searched using electronic databases such as ISI web of knowledge, ProQuest, ScienceDirect, OATD, Scopus, OpenThesis, PubMed, and Google Scholar. The search for pre-electronic literature such as conference papers, scientific articles, books, book chapters, dissertations, and theses was carried out at the university library. Literature studies revealed that L. acida is mainly used for injuries, inflammation and pain, gastrointestinal problems, fever and malaria, gynecological and pregnancy disorders, ethnoveterinary medicine, hemorrhoids, skin diseases, and infections. Phytochemical compounds identified from the species include alkaloids, cardiac glycosides, flavonoids, phenols, saponins, steroids, tannins, and terpenoids. Pharmacological studies revealed that L. acida extracts have anthelmintic, antibacterial, antidiarrheal, anti-inflammatory, antimycobacterial, antioxidant, estrogenic, fertility, hyaluronidase, phospholipase A2, proteolytic, and vibriocidal activities. Given the importance of L. acida as herbal medicine, there is a need for detailed studies aimed at establishing the efficacy, clinical relevance, and safety of the plant extracts and compounds.


2020 ◽  
Vol 11 (4) ◽  
pp. 5948-5955
Author(s):  
Alfred Maroyi

Cissampelos capensis L.f. is a perennial climber widely used as a traditional medicine in South Africa. This study was aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of C. capensis. Documented information on the pharmacological properties, phytochemistry and medicinal uses of C. capensis was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study revealed that leaf, rhizome and root infusions and decoctions of C. capensis are mainly used as a blood purifier, and traditional medicines for respiratory problems, ulcers, sores and wounds, skin and stomach cancers, snakebite, sexually transmitted infections, skin diseases, diabetes and gastrointestinal problems. Phytochemical compounds identified from the species include alkaloids, essential oils, flavonoids, phenolics, saponins and tannins. Pharmacological research revealed that C. capensis extracts and compounds isolated from the species have anthelmintic, antibacterial, antifungal, antidiabetic, antimalarial, hepatotoxicity, spermatozoa and cytotoxicity activities. Documentation of the medicinal uses, phytochemistry and pharmacological properties of C. capensis is vital as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. There is a need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since C. capensis contains potentially toxic compounds.


2020 ◽  
Vol 10 (5) ◽  
pp. 196-204
Author(s):  
Alfred Maroyi

Gymnanthemum coloratum is a shrub or a small tree widely used as traditional medicine throughout its distributional range in tropical Africa. The current study is aimed at reviewing the phytochemistry, pharmacological properties and medicinal uses of G. coloratum. Literature on pharmacological properties, phytochemistry and medicinal uses of G. coloratum was obtained from numerous internet sources such as Scopus, Elsevier, SciFinder, Google Scholar, Pubmed, ScienceDirect, BMC and Web of Science. Other sources of information included pre-electronic sources such as journal articles, theses, book chapters, books and other scientific publications obtained from the university library. The articles published between 1964 and 2020 were used in this study. The current study showed that G. coloratum is used as an anthelmintic, and traditional medicine for reproductive problems, schistosomiasis, liver diseases, sexually transmitted infections, diabetes, sores and wounds, respiratory problems, malaria, skin diseases, fever and gastro-intestinal problems. Ethnopharmacological research identified glaucolides, lactones, amino acids, essential oils, alkaloids, anthocyanins, cardenolids, coumarins, flavonoids, glycosides, leucoanthocyanins, phenols, quinones, reducing sugars, saponins, steroids, tannins, terpenoids and triterpenes from the aerial parts, leaves, roots and stems of G. coloratum. The aerial parts, leaves, roots and whole plant parts of G. coloratum and compounds isolated from the species exhibited anthelmintic, antimicrobial, anti-Blastocystis, anti-inflammatory, anti-sickling, insecticidal and larvicidal, antiplasmodial, antimalarial, antioxidant, antiproliferative, anti-Toxoplasma, hypoglycaemic and antidiabetic and cytotoxicity activities. Gymnanthemum coloratum should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


2020 ◽  
Vol 10 (5) ◽  
pp. 230-238
Author(s):  
Alfred Maroyi

Baccharoides adoensis is a shrub widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis. Documented information on the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis was collected from several online sources which included Scopus, Google Scholar, PubMed and Science Direct. Additional information on the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications sourced from the university library. The articles published between 1962 and 2020 were used in this study. This study showed that the roots, flowers, stems, and leaves of B adoensis are widely used as ethnoveterinary medicine and traditional medicines for backbone pain, reproductive problems, kidney diseases, fever and febrile complaints, wounds, ulcers, sexually transmitted infections, skin complaints, malaria, gastro-intestinal problems and respiratory problems. Phytochemical compounds identified from the species include alkaloids, carbohydrates, chondrillasterol, flavonoids, free sugars, glaucolides, glycosides, phenols, proanthocyanidin, saponins, steroids, tannins and terpenoids. Pharmacological research revealed that B. adoensis extracts and compounds isolated from the species have antimicrobial, antimycobacterial, anti-inflammatory, antioxidant, antiplasmodial, anti-pyretic, antitrypanosomal, antileishmanial, anti-ulcer and gastroprotective, immunomodulating, inhibition of Helicobacter pylori adhesion, larvicidal, cytotoxicity and toxicity activities. Baccharoides adoensis should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


Author(s):  
Alfred Maroyi

Lannea discolor is an important component of the traditional, complementary, and alternative medicine health-care systems in several countries. This study is aimed at reviewing the botany, ethnomedicinal uses, phytochemical and biological activities of L. discolor. Information on its botany, medicinal uses, chemistry and pharmacological properties was undertaken using electronic databases such as Pubmed, SCOPUS, Medline, SciFinder, ScienceDirect, Google Scholar, EThOS, ProQuest, OATD and Open-thesis. Pre-electronic literature was sourced from the University Library. The species is used as herbal medicine for 24 human diseases. The major diseases and ailments treated using concoctions prepared from L. discolor include gastrointestinal problems, gonorrhea, infertility in women, convulsions, dizziness, injury, and wounds. Different aqueous and organic extracts of L. discolor exhibited anthelmintic, antibacterial, antimycobacterial, antifungal, antioxidant, antiplasmodial, and nematicidal activities. Detailed studies on the phytochemistry, pharmacological, and toxicological properties of L. discolor are required to correlate the medicinal uses of the species with its phytochemistry and pharmacological properties.


Scientifica ◽  
2018 ◽  
Vol 2018 ◽  
pp. 1-17 ◽  
Author(s):  
Alfred Maroyi

Vangueria madagascariensisJ. F. Gmel. is a plant species regarded as an important fruit tree and medicinal plant in sub-Saharan Africa. This study critically reviewed the nutritional value, phytochemistry, medicinal uses, and pharmacological properties ofV. madagascariensis. Relevant information on food and medicinal uses of the species was collected from electronic databases such as ISI Web of Knowledge, ProQuest, ScienceDirect, OATD, Scopus, OpenThesis, PubMed, and Google Scholar, and preelectronic literatures were obtained from the university library covering the period 1966 to 2018. Literature studies revealed thatV. madagascariensishas been integrated into farming systems as a fruit tree to support income and nutritional security of households in the region.Vangueria madagascariensisis used as a herbal medicine against diabetes, gastrointestinal problems, malaria, pain, parasitic worms, and skin diseases. Phytochemical compounds identified from the species include alcohols, aldehydes, esters, furanoids, ketones, and terpenoids. Pharmacological studies revealed thatV. madagascariensisextracts have antibacterial, anticonvulsant, antidiabetic, antifungal, anti-inflammatory, antioxidant, cytotoxicity, antimalarial, and antiplasmodial properties.Vangueria madagascariensisshould be subjected to detailed nutritional, pharmacological, and toxicological evaluations aimed at correlating the traditional uses of the species and the scientific evidence as well as establishing the efficacy, clinical relevance, safety, and mechanisms of action of the plant extracts and compounds.


Author(s):  
ALFRED MAROYI

The bark, leaves, roots, and twigs of Heteropyxis natalensis are widely used as herbal medicines in Southern Africa. The aim of this study was to review the phytochemical and ethnopharmacological properties of H. natalensis so as to provide baseline data required for evaluating the therapeutic potential of the species. Information on the botanical profile, medicinal uses, phytochemistry, and pharmacological properties of H. natalensis was undertaken using databases such as ScienceDirect, SciFinder, PubMed, Google Scholar, Medline, SCOPUS, EThOS, ProQuest, OATD, and open-thesis. Pre-electronic literature of conference papers, scientific articles, books, book chapters, dissertations, and theses were carried out at the university library. Literature search revealed that H. natalensis is used as an aphrodisiac, anti-infection, blood purifier, decongestant, for weaning, ethnoveterinary medicine and as herbal medicine for bleeding disorders, gums, nose, colds, gum infections, impotence, menorrhagia, respiratory disorders, toothache, and wounds. Phytochemical compounds identified from the species include essential oils, 3β-hydroxylup-20(29)-en-28-al, (E)-1-(2’,4’-dihyroxy,5’- methoxy,3’-methylphenyl)-3-phenylprop-2-en-1-one, (2E)-2-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-5-methoxy-6,6-dimethylcyclohex-4-ene- 1,3-dione, 2’,4’-dihydroxy-6’-methoxy-3’,5’-dimethylchalcone, 3’,4’,5’-tri-O-methyl-3,4-methylenedioxy ellagic acid, 3,5,7-trihydroxyflavan, 5-hydroxy- 7-methoxy-6-methylflavanone, aurentiacin A, betulinic acid, cardamomin, lupenone, lupeol, quercetin, and sitost-4-en-3-one. Pharmacological studies revealed that H. natalensis extracts and compounds have antibacterial, antimycobacterial, antifungal, antioxidant, anti-inflammatory, cytotoxicity, and pro-inflammatory activities. Detailed studies are required to establish the efficacy, clinical relevance, safety and mechanisms of action of the plant extracts, and compounds of H. natalensis.


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