scholarly journals MR Imaging-Histology Correlation by Tailored 3D-Printed Slicer in Oncological Assessment

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
D. Baldi ◽  
M. Aiello ◽  
A. Duggento ◽  
M. Salvatore ◽  
C. Cavaliere
Keyword(s):  
3D Printing ◽  
In Vivo Imaging ◽  
Computer Aided Design ◽  
Quantitative Imaging ◽  
Production Costs ◽  
Imaging Data ◽  
Histopathological Correlation ◽  
Custom Made ◽  
Aided Design

3D printing and reverse engineering are innovative technologies that are revolutionizing scientific research in the health sciences and related clinical practice. Such technologies are able to improve the development of various custom-made medical devices while also lowering design and production costs. Recent advances allow the printing of particularly complex prototypes whose geometry is drawn from precise computer models designed on in vivo imaging data. This review summarizes a new method for histological sample processing (applicable to e.g., the brain, prostate, liver, and renal mass) which employs a personalized mold developed from diagnostic images through computer-aided design software and 3D printing. Through positioning the custom mold in a coherent manner with respect to the organ of interest (as delineated by in vivo imaging data), the cutting instrument can be precisely guided in order to obtain blocks of tissue which correspond with high accuracy to the slices imaged. This approach appeared crucial for validation of new quantitative imaging tools, for an accurate imaging-histopathological correlation and for the assessment of radiogenomic features extracted from oncological lesions. The aim of this review is to define and describe 3D printing technologies which are applicable to oncological assessment and slicer design, highlighting the radiological and pathological perspective as well as recent applications of this approach for the histological validation of and correlation with MR images.

scholarly journals Custom-made artificial eyes using 3D printing for dogs: A preliminary study

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242274
Author(s):  
So-Young Park ◽  
Jeong-Hee An ◽  
Hyun Kwon ◽  
Seo-Young Choi ◽  
Ka-Young Lim ◽  
...  
Keyword(s):  
3D Printing ◽  
Computer Aided Design ◽  
Companion Animals ◽  
Manufacturing Cost ◽  
Artificial Eye ◽  
Custom Made ◽  
3D Printed ◽  
Preliminary Study ◽  
Ocular Implant

Various incurable eye diseases in companion animals often result in phthisis bulbi and eye removal surgery. Currently, the evisceration method using silicone balls is useful in animals; however, it is not available to those with impaired cornea or severe ocular atrophy. Moreover, ocular implant and prostheses are not widely used because of the diversity in animal size and eye shape, and high manufacturing cost. Here, we produced low-cost and customized artificial eyes, including implant and prosthesis, using computer-aided design and three-dimensional (3D) printing technique. For 3D modeling, the size of the artificial eyes was optimized using B-mode ultrasonography. The design was exported to STL files, and then printed using polycaprolactone (PCL) for prosthesis and mixture of PCL and hydroxyapatite (HA) for ocular implant. The 3D printed artificial eyes could be produced in less than one and half hour. The prosthesis was painted using oil colors and biocompatible resin. Two types of eye removal surgery, including evisceration and enucleation, were performed using two beagle dogs, as a preliminary study. After the surgery, the dogs were clinically evaluated for 6 months and then histopathological evaluation of the implant was done. Ocular implant was biocompatible and host tissue ingrowth was induced after in vivo application. The custom-made prosthesis was cosmetically excellent. Although long-term clinical follow-up might be required, the use of 3D printed-customized artificial eyes may be beneficial for animals that need personalized artificial eye surgery.

scholarly journals Prototype of Augmented Reality Technology for Orthodontic Bracket Positioning: An In Vivo Study

2021 ◽  
Vol 11 (5) ◽  
pp. 2315
Author(s):  
Yu-Cheng Lo ◽  
Guan-An Chen ◽  
Yin Chun Liu ◽  
Yuan-Hou Chen ◽  
Jui-Ting Hsu ◽  
...  
Keyword(s):  
Augmented Reality ◽  
Navigation System ◽  
Computer Aided Design ◽  
Control Group ◽  
Orthodontic Bracket ◽  
Bracket Position ◽  
Aided Design ◽  
Clinical Error ◽  
And Control

To improve the accuracy of bracket placement in vivo, a protocol and device were introduced, which consisted of operative procedures for accurate control, a computer-aided design, and an augmented reality–assisted bracket navigation system. The present study evaluated the accuracy of this protocol. Methods: Thirty-one incisor teeth were tested from four participators. The teeth were bonded by novice and expert orthodontists. Compared with the control group by Boone gauge and the experiment group by augmented reality-assisted bracket navigation system, our study used for brackets measurement. To evaluate the accuracy, deviations of positions for bracket placement were measured. Results: The augmented reality-assisted bracket navigation system and control group were used in the same 31 cases. The priority of bonding brackets between control group or experiment group was decided by tossing coins, and then the teeth were debonded and the other technique was used. The medium vertical (incisogingival) position deviation in the control and AR groups by the novice orthodontist was 0.90 ± 0.06 mm and 0.51 ± 0.24 mm, respectively (p < 0.05), and by the expert orthodontist was 0.40 ± 0.29 mm and 0.29 ± 0.08 mm, respectively (p < 0.05). No significant changes in the horizontal position deviation were noted regardless of the orthodontist experience or use of the augmented reality–assisted bracket navigation system. Conclusion: The augmented reality–assisted bracket navigation system increased the accuracy rate by the expert orthodontist in the incisogingival direction and helped the novice orthodontist guide the bracket position within an acceptable clinical error of approximately 0.5 mm.

scholarly journals Upgrade and Repair of the Instrumentation Equipment on the ISS RS Simulators Using FDM 3D Printing Technology.

2021 ◽  
pp. 97-110
Author(s):  
V.V. Batrakov ◽  
A.I. Krylov ◽  
V.N. Saev ◽  
B.N. Nefyodov ◽  
V.M. Novichkov ◽  
...  
Keyword(s):  
3D Printing ◽  
Computer Aided Design ◽  
Cad Tools ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Computer Aided ◽  
Aided Design

The paper presents space simulators (SS), types of instrumentation equipment installed on the workplaces of the space simulators operators (SSOPW), multi-functional display panel (MFDP), computer-aided design (CAD) tools, 3D printing technologies.

scholarly journals Engineering working operations based on parameters of product manufacturability using a computer-aided design algorithm

2022 ◽  
Vol 25 (6) ◽  
pp. 708-719
Author(s):  
D. A. Ishenin ◽  
A. S. Govorkov
Keyword(s):  
Computer Aided Design ◽  
Production Costs ◽  
Machining Process ◽  
Processing Route ◽  
Mechanical Processing ◽  
Design Algorithm ◽  
Industrial Data ◽  
Production Processes ◽  
Computer Aided ◽  
Aided Design

The study aimed to develop an algorithm for computer-aided design (CAD) of working operations. A processing route for machining components was developed based on the criteria of production manufacturability, industrial data and a digital model of the product. The process of machining a workpiece was analysed using a method of theoretical separation. The machining process of a frame workpiece was used as a model. The identified formal parameters formed a basis for developing a CAD algorithm and a model of manufacturing route associated with the mechanical processing of a work-piece applying a condition-action rule, as well as mathematical logic. The research afforded a scheme for selecting process operations, given the manufacturability parameters of a product design. The concept of CAD algorithm was developed to design a production process of engineering products with given manufacturability parameters, including industrial data. The principle of forming a route and selecting a machining process was proposed. Several criteria of production manufacturability (labour intensity, consumption of materials, production costs) were selected to evaluate mechanical processing. A CAD algorithm for designing technological operations considering the parameters of manufacturability was developed. The algorithm was tested by manufacturing a frame workpiece. The developed algorithm can be used for reducing labour costs and development time, at the same time as improving the quality of production processes. The formalisation of process design is a crucial stage in digitalisation and automation of all production processes.

scholarly journals Desain dan Pembuatan Prototype Piston Honda MEGAPRO FI Menggunakan 3D Printing

2020 ◽  
Vol 1 (2) ◽  
pp. 81-91
Author(s):  
Frince Marbun ◽  
Richard A.M. Napitupulu
Keyword(s):  
3D Printing ◽  
Computer Aided Design ◽  
Fused Deposition Modeling ◽  
Layer By Layer ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Fused Deposition ◽  
Deposition Modeling ◽  
Manufacturing Technologies ◽  
Aided Design

3D printing technology has great potential in today's manufacturing world, one of its uses is in making miniatures or prototypes of a product such as a piston. One of the most famous and inexpensive 3D printing (additive manufacturing) technologies is Fused Deposition Modeling (FDM), the principle FDM works by thermoplastic extrusion through a hot nozzle at melting temperature then the product is made layer by layer. The two most commonly used materials are ABS and PLA so it is very important to know the accuracy of product dimensions. FDM 3D Printing Technology is able to make duplicate products accurately using PLA material. FDM machines work by printing parts that have been designed by computer-aided design (CAD) and then exported in the form of STL or .stl files and uploaded to the slicer program to govern the printing press according to the design. Using Anet A8 brand 3D printing tools that are available to the public, Slicing of general CAD geometry files such as autocad and solidwork is the basis for making this object. This software is very important to facilitate the design process to be printed. Some examples of software that can be downloaded and used free of charge such as Repetier-Host and Cura. by changing the parameters in the slicer software is very influential in the 3D printing manufacturing process.

scholarly journals ADDITIVE MANUFACTURING - APPLICATION OPPORTUNITIES FOR THE AVIATION INDUSTRY

2015 ◽  
Vol 6 (2) ◽  
pp. 63-86
Author(s):  
Dipesh Dhital ◽  
Yvonne Ziegler
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
Computer Aided Design ◽  
Free Form ◽  
Aviation Industry ◽  
Layer By Layer ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Subtractive Manufacturing ◽  
Aided Design

Additive Manufacturing also known as 3D Printing is a process whereby a real object of virtually any shape can be created layer by layer from a Computer Aided Design (CAD) model. As opposed to the conventional Subtractive Manufacturing that uses cutting, drilling, milling, welding etc., 3D printing is a free-form fabrication process and does not require any of these processes. The 3D printed parts are lighter, require short lead times, less material and reduce environmental footprint of the manufacturing process; and is thus beneficial to the aerospace industry that pursues improvement in aircraft efficiency, fuel saving and reduction in air pollution. Additionally, 3D printing technology allows for creating geometries that would be impossible to make using moulds and the Subtractive Manufacturing of drilling/milling. 3D printing technology also has the potential to re-localize manufacturing as it allows for the production of products at the particular location, as and when required; and eliminates the need for shipping and warehousing of final products.

Parametric geometry model design of a wingsuit

2020 ◽  
Vol 32 (5) ◽  
pp. 691-705
Author(s):  
Nazanin Ansari ◽  
Sybille Krzywinski
Keyword(s):  
Computer Aided Design ◽  
Early Stage ◽  
Three Dimensional ◽  
Production Costs ◽  
Process Chain ◽  
Content Type ◽  
Geometry Model ◽  
Computer Aided ◽  
2D Pattern ◽  
Aided Design

PurposeThis paper aims to introduce a process chain spanning from scanned data to computer-aided engineering and further required simulations up to the subsequent production. This approach has the potential to reduce production costs and accelerate the procedure.Design/methodology/approachA parametric computer-aided design (CAD) model of the flyer wearing a wingsuit is created enabling easy changes in its posture and the wingsuit geometry. The objective is to track the influence of geometry changes in a timely manner for following simulation scenarios.FindingsAt the final stage, the two-dimensional (2D) pattern cuts were derived from the developed three-dimensional (3D) wingsuit, and the results were compared with the conventional ones used in the first stages of the wingsuit development.Originality/valueProposing a virtual development process chain is challenging; apart from the fact that the CAD construction of a wingsuit flyer – in itself posing a complicated task – is required at a very early stage of the procedure.

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