Relationship between Body Mass Index and T-Scores of Bone Mineral Density in the Hip and Spine Regions among Older Adults with Diabetes: A Retrospective Review

Diabetes mellitus (DM) cases are increasing worldwide, especially in Saudi Arabia. Previous studies suggested a positive relationship between body mass index (BMI) and bone mineral density (BMD) levels. Generally, patients with low BMI (<18.5 kg/m2) have reduced BMD levels and, thus, low T-scores; hence, they are categorized as osteopenic or osteoporotic. In this study, we aimed to determine whether a relationship between BMI and BMD T-scores in the hip and spine regions of patients with diabetes exists. This retrospective record review investigated older adult patients with diabetes in King Abdulaziz University Hospital (n=198; age 50–90 years) who underwent BMD scan between January 1, 2016, and June 25, 2018, regardless of their sex but limited to type 2 DM. The height and weight of all subjects were recorded, and BMI was calculated and categorized. We used SPSS version 21 for data analysis; measures of central tendencies, Pearson’s correlations, chi-square tests, and independent t-tests were employed. We found positive relationships between BMI and BMD T-scores in the hip and spine regions (right femoral neck: R=+0.214, P≤0.002; total right hip: R=+0.912, P≤0.001; left femoral neck: R=+0.939, P≤0.001; total left hip: R=+0.885, P≤0.001; and total lumbar region: R=+0.607, P≤0.001). Low BMI (<18.5 kg/m2) could be a risk factor for osteoporosis, whereas normal/high BMI could be protective against osteoporosis among adults with diabetes.

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Relationship of body mass index with bone mineral density in postmenopausal women: an Indian perspective

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20194881 ◽

2019 ◽

Vol 8 (11) ◽

pp. 4490

Author(s):

Avani Goyal ◽

Veena Ganju Malla

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Body Weight ◽

Lumbar Spine ◽

Femoral Neck ◽

Body Mass ◽

Bone Mineral ◽

Mineral Density ◽

Low Bmi ◽

Relationship Of

Background: Osteoporosis is a common health problem that affects postmenopausal females, leading to increased susceptibility to fractures. Body mass index (BMI) has been shown to be an important predictor of bone mineral density (BMD) with increased body weight correlating with positive influence on bone metabolism. Low BMI predisposes postmenopausal females to rapid bone loss and low bone mass, crucial in the pathogenesis of osteoporosis. However, a specific BMI value chart to accurately predict osteoporosis remains to be fully established. The present study aimed to investigate the relationship of BMI and BMD in postmenopausal Indian females.Methods: 90 healthy postmenopausal females with 1-5 years of menopause were enrolled in the study. Subjects were categorized according to their BMI into normal, overweight and obese. BMD was assessed using dual energy X-ray absorptiometry (DEXA) scan at L1-L4 vertebrae and femoral neck and expressed as T-scores. Quantitative variables were compared using ANOVA/Kruskal Wallis Test.Results: Bone mineral density was significantly higher in the obese group as compared to normal BMI group at both lumbar spine (p=0.001) and femoral neck (p=0.001). BMD at lumbar spine was lower than that at femoral neck across all the three groups of BMI.Conclusions: BMI and body weight are important factors affecting BMD. Postmenopausal females with low BMI are more likely to have osteopenia and osteoporosis and are thus at an increased risk of pathological fractures. Routine BMD monitoring in postmenopausal females with low BMI may be necessary to initiate early clinical interventions for osteoporosis.

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AB1324 Studying the relationship between body mass index, bmi, and bone mineral density, bmd, of lumbar vertebrae and femoral neck

10.1136/annrheumdis-2018-eular.4202 ◽

2018 ◽

Author(s):

K. Talash ◽

M. Bukhari

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Femoral Neck ◽

Body Mass ◽

Bone Mineral ◽

Lumbar Vertebrae ◽

Mineral Density ◽

The Relationship

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Body Mass Index May Positively Correlate with Bone Mineral Density of Lumbar Vertebra and Femoral Neck in Postmenopausal Females

Medical Science Monitor ◽

10.12659/msm.895512 ◽

2016 ◽

Vol 22 ◽

pp. 145-151 ◽

Cited By ~ 15

Author(s):

Shi-Feng Wu ◽

Xin-Jie Du

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Femoral Neck ◽

Body Mass ◽

Bone Mineral ◽

Lumbar Vertebra ◽

Mineral Density

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Correlation of body mass index and bone mineral density in menopausal women

Endocrine Abstracts ◽

10.1530/endoabs.70.ep88 ◽

2020 ◽

Author(s):

Pejicic Snjezana Popovic ◽

Nina Pejicic ◽

Aleksandra Grbic

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Body Mass ◽

Bone Mineral ◽

Mineral Density ◽

Menopausal Women

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Effect Of Body Mass Index On Bone Mineral Density Is Age-specific

Nutrition Metabolism and Cardiovascular Diseases ◽

10.1016/j.numecd.2021.02.027 ◽

2021 ◽

Author(s):

Lavanya Cherukuri ◽

April Kinninger ◽

Divya Birudaraju ◽

Suvasini Lakshmanan ◽

Dong Li ◽

...

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Body Mass ◽

Bone Mineral ◽

Mineral Density

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The relationship between body mass index and physical activity levels in relation to bone mineral density in premenopausal and postmenopausal women

Archives of Osteoporosis ◽

10.1007/s11657-013-0162-z ◽

2013 ◽

Vol 8 (1-2) ◽

Cited By ~ 21

Author(s):

James Wee ◽

Bo Yang Jonathan Sng ◽

Liang Shen ◽

Chin Tat Lim ◽

Gurpal Singh ◽

...

Keyword(s):

Physical Activity ◽

Bone Mineral Density ◽

Body Mass Index ◽

Postmenopausal Women ◽

Body Mass ◽

Bone Mineral ◽

Activity Levels ◽

Mineral Density ◽

Physical Activity Levels ◽

The Relationship

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Decreased Bone Density in Adolescent Girls With Anorexia Nervosa

PEDIATRICS ◽

10.1542/peds.86.3.440 ◽

1990 ◽

Vol 86 (3) ◽

pp. 440-447 ◽

Cited By ~ 1

Author(s):

Laura K. Bachrach ◽

David Guido ◽

Debra Katzman ◽

Iris F. Litt ◽

Robert Marcus

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Anorexia Nervosa ◽

Bone Density ◽

Bone Mass ◽

Body Mass ◽

Bone Mineral ◽

Whole Body ◽

Mineral Density ◽

Control Subjects

Osteoporosis develops in women with chronic anorexia nervosa. To determine whether bone mass is reduced in younger patients as well, bone density was studied in a group of adolescent patients with anorexia nervosa. With single- and dual-photon absorptiometry, a comparison was made of bone mineral density of midradius, lumbar spine, and whole body in 18 girls (12 to 20 years of age) with anorexia nervosa and 25 healthy control subjects of comparable age. Patients had significantly lower lumbar vertebral bone density than did control subjects (0.830 ± 0.140 vs 1.054 ± 0.139 g/cm2) and significantly lower whole body bone mass (0.700 ± 0.130 vs 0.955 ± 0.130 g/cm2). Midradius bone density was not significantly reduced. Of 18 patients, 12 had bone density greater than 2 standard deviations less than normal values for age. The diagnosis of anorexia nervosa had been made less than 1 year earlier for half of these girls. Body mass index correlated significantly with bone mass in girls who were not anorexic (P < .05, .005, and .0001 for lumbar, radius, and whole body, respectively). Bone mineral correlated significantly with body mass index in patients with anorexia nervosa as well. In addition, age at onset and duration of anorexia nervosa, but not calcium intake, activity level, or duration of amenorrhea correlated significantly with bone mineral density. It was concluded that important deficits of bone mass occur as a frequent and often early complication of anorexia nervosa in adolescence. Whole body is considerably more sensitive than midradius bone density as a measure of cortical bone loss in this illness. Low body mass index is an important predictor of this reduction in bone mass.

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