scholarly journals The Epidemiology of Primary Central Nervous System Tumors at the National Neurologic Institute in Saudi Arabia: A Ten-Year Single-Institution Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Amna Almutrafi ◽  
Yara Bashawry ◽  
Wafaa AlShakweer ◽  
Musa Al-Harbi ◽  
Abdullah Altwairgi ◽  
...  

Objectives. This study is aimed at describing the epidemiological trends of primary CNS tumors in children and adults at the National Neurologic Institute in Saudi Arabia. Methods. A retrospective epidemiological approach was used where data was obtained from the department of pathology registry files and pathology reports. The records of all patients registered from January 2005 to December 2014 with a diagnosis of primary CNS tumor (brain and spinal cord) were selected. Data about sex, age, tumor location, and histologic type were collected. The classification was based on the International Classification of Diseases for Oncology, 3rd Edition (ICD-O-3). Results. Nine hundred and ninety-two (992) cases of primary CNS tumors throughout the ten years (2005 to 2014) were reviewed. There were 714 (71.97%) adults and 278 (28.02%) in the pediatric age group. Nonmalignant tumors dominated the adult population (60.08%) while malignant tumors were more frequent in the pediatric population. Gliomas constituted the most common neoplastic category in children and adults. The most common single tumor entity was meningioma (26.99%, ICD-O-3 histology codes 9530/0, 9539/1, and 9530/3). Medulloblastomas (ICD-O-3 histology codes 9470, 9471, and 9474) were the most common single tumor entity in the pediatric age group (26.62%). Conclusions. This is an institution-based, detailed, and descriptive epidemiological study of patients with primary CNS tumors in Saudi Arabia. In contrast to other regional and international studies, the medulloblastomas in our institution are more frequent than pilocytic astrocytomas. Limitations to our study included the referral bias and histology-based methodology.

2019 ◽  
Vol 40 (10) ◽  
pp. 1063-1066
Author(s):  
Waseem Alzamil ◽  
Fatima Alshamlan ◽  
Hamdah Alkhaldi ◽  
Alhanoof Almubaiyd ◽  
Alaa Alsaif ◽  
...  

PEDIATRICS ◽  
1978 ◽  
Vol 62 (6) ◽  
pp. 1026-1030
Author(s):  
Edward Tabor ◽  
Richard Jones ◽  
Robert J. Gerety ◽  
Jacques A. Drucker ◽  
A. R. Colon

Sera from 95 adolescents were examined for markers of hepatitis B virus (HBV) infection and hepatitis A virus (HAV) infection. HBV markers were found in eight adolescents (8%) and evidence of previous HAV infection was found in 18 adolescetits (19%); none had a history of clinically recognizable hepatitis. These findings support the growing evidence that HBV and HAV infections are diseases of the pediatric age group, amid that testing of HBV vaccines when they become available for patient use will have to include a pediatric population.


1992 ◽  
Vol 2 (1) ◽  
pp. 100-102
Author(s):  
Christopher L. Case ◽  
Paul C. Gillette ◽  
C. Osborne Shuler

SummaryThe feasibility and efficacy of radiofrequency catheter ablation of medically resistant supraventricular tachycardia is a promising technique with applications in the pediatric age group. The limitations of this procedure in the pediatric population, however, have yet to be delineated. We herein report a case of incessant reentrant supraventricular tachycardia in a two month old infant which was resistant to pharmacologic therapy, yet successfully treated by radiofrequency catheter ablation.


2018 ◽  
Vol 21 (6) ◽  
pp. 568-573 ◽  
Author(s):  
Maryam K Al Badi ◽  
Ibrahim Al-Alwan ◽  
Mohammed Al-Dubayee ◽  
Ayed Al-Anzi ◽  
Maram S Al Turki ◽  
...  

Oncocytic tumors are epithelial neoplasms that occur in various organs, including adrenal glands. Oncocytic adrenocortical adenomas and carcinomas are uncommon but well-known pathological entities in adults. However, generally oncocytic tumors, particularly in the adrenal glands, are very rare in the pediatric age-group. Most oncocytic adrenal tumors are not functional. We present a rare case of right-sided, functional oncocytic adrenocortical adenoma in a 5-year-old boy, who presented with clinical manifestations of precocious puberty and Cushing syndrome. Laparoscopic adrenalectomy showed a well-defined mass weighing 8.4 g and measuring 3 cm in maximum dimension. Histological examination demonstrated no features suggestive of aggressive biological behavior. The patient showed no evidence of recurrent or metastatic disease and continued to have normal serum hormonal levels 28 months following the surgery. In this report, we discuss the clinicopathological characteristics of this rare pathological entity and briefly review the literature on functional oncocytic adrenal tumors in the pediatric population.


2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Riti Bhalla ◽  
Chantal Soobhanath ◽  
Sarah Celebi ◽  
Manoj Chhabra ◽  
Pramod Narula

Syncope is common in the pediatric population and occurs in up to 15 percent of children prior to the end of adolescence. While the etiology of syncope in children is often benign and the majority of cases can be explained by isolated changes in vasomotor tone, a thorough evaluation is warranted to rule out more serious, life-threatening causes of syncope. Here, we present three atypical cases of syncope: a young judo player with recurrent syncope and dizziness, a teenage boy with syncopal episodes always preceded by stretching, and a child who experienced urticaria before losing consciousness. Herein, we review the pathophysiology, diagnosis, and management of syncope in children and adolescents.


2017 ◽  
pp. 28-31
Author(s):  
Shashi Sharma ◽  
Sakshi Dewan ◽  
Naveen Bhardwaj ◽  
Mir Aziz ◽  
Shilpa Singh ◽  
...  

2021 ◽  
Vol 15 (1) ◽  
pp. 431-435
Author(s):  
Mohamed Mansy ◽  
Mostafa Kotb ◽  
Mohamed Abouheba

Congenital lumbar hernias are uncommonly seen in the pediatric age group, with only about 60 cases reported in the literature. It is usually accompanied by a multitude of congenital anomalies involving different organ systems of the body. For instance, it may involve the ribs, spine, muscles, and the kidneys. Herein, we report a case of congenital lumbar hernia in an 8-month-old boy who underwent an operative repair using a mesh with an uneventful outcome.


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