scholarly journals Laryngeal Papillomatosis in Adults: Assessment for Ten Years at the ENT Department of the National University Hospital of Fann (Dakar, Senegal)

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
N. Ndour ◽  
S. Maiga ◽  
A. Houra ◽  
R. E. A. Deguenonvo ◽  
C. Ndiaye ◽  
...  

Objectives. The aim of this study was to describe the epidemiological, diagnostic, and therapeutic aspects of adult laryngeal papillomatosis in Senegal. Patients and Methods. This is a retrospective descriptive study of patients aged above 18 years with laryngeal papillomatosis and followed at the ENT department of the NUH of Fann between 01 January 2009 and 31 December 2018. Results. The mean age at diagnosis was 37.74 years and a sex ratio of 0.93. The 20–29 age group was the most represented (45.2%). The average consultation delay was 8.34 years. All patients had dysphonia at the moment of the diagnostic and in 35.5% of cases, and it was associated with laryngeal dyspnea. Glottis localization was present in all our patients, i.e., 100% of the cases. A tracheotomy was performed in 9.67% of cases. All of our patients have had their papilloma peeled per endoscopic with tweezers. No cases of malignant degeneration were found in our study. Conclusion. Laryngeal papillomatosis is the most common benign tumor of the larynx in both children and adults. Despite the progress of endoscopy and antiviral treatments, its treatment poses many problems in our undermedicalized countries.

2017 ◽  
Vol 16 (3) ◽  
pp. 224-227
Author(s):  
MATEUS BERGAMO LOMAZ ◽  
LEONEL ANTÔNIO FREITAS SALES NETTO ◽  
MARIO SILVA GARROTE FILHO ◽  
ALEX PEREIRA ALVES ◽  
FABIANO RICARDO DE TAVARES CANTO

ABSTRACT Objective: To analyze the epidemiological profile of patients with spinal fractures and the characteristics of the population at risk attended at a university hospital. Methods: The study population is composed of 202 patients diagnosed and treated for vertebral fracture due to trauma. The variables were correlated with each other and the correlations with p<0.05 were considered statistically significant. Results: The ratio of incidence of trauma between the sexes was 3:1 for males. The mean age was 37 years and the age group with the highest incidence was between 20 and 39 years. Traffic accidents were the most frequent mechanism (51.2%) and secondly, falls (33.2%). There was a statistical correlation between trauma mechanisms to age group and region of the spine. The first lumbar vertebra (L1) fracture alone accounted for 21.5% of all cases studied associated with the fall mechanism. Spinal cord injury was recorded in 33.7% of the individuals in the sample. A total of 57.3% of the patients were submitted to surgical treatment and 41.7% to the conservative treatment. The mean hospitalization time was 15 days. Conclusions: Spinal fractures are important determinants of morbidity and mortality in the population with a major impact on economically active individuals, especially males. They are directly associated to traffic accidents in the young population and to falls in the higher age brackets. Primary prevention of trauma is the main mechanism for change in this scenario.


2018 ◽  
Vol 7 (4) ◽  
pp. 173-179
Author(s):  
Suman Raj Tamrakar ◽  
Ramesh Makaju ◽  
Abha Shrestha ◽  
Suresh Kayastha

Background: Ovarian tumours account for 15% to 25% of all primary malignancy and the leading cause of death from gynaecolgical malignancies. There are limited publications related to ovarian tumours from Nepal. Ovarian related surgeries are the common surgeries in Kathmandu University Hospital. This study aims to provide basic information related to ovarian tumours from this geographical region of Nepal. Objectives: To review the nature of ovarian problems and certain socio-demographic information namely: caste, age, address and co-morbid condition of the patients presenting with ovarian problems. Methodology: This is a retrospective study of patients seeking surgical treatment of ovarian lesions in Kathmandu University Hospital from January 1, 2011 to June 30, 2018. This study was undertaken by reviewing the inpatient, outpatients and OT records in the Department of Obstetrics and Gynaecology and the records from Department of Pathology. All the files and computer records were reviewed and analyzed for nature of ovarian problems and certain demographic variables. Results: Out of the 860 cases, about 61% were non-neoplastic while benign ovarian tumours and malignant ovarian tumours were 35% and 3.7 % respectively. Almost one third of the cases were of Brahmin/Chhetri (37.3%) and 58.3% of the patients were from Kavre district. Mean age of the patients with ovarian problems was 34.89±11.15 years (range 12-72 years). There was no statistically significant difference between the mean age of patients with non-neoplastic ovarian lesions and neoplastic ovarian lesions (p value = 0.3371). There was statistically significant difference between the mean age of patients with benign ovarian tumours and malignant ovarian tumours (p value = 0.0001). And malignant ovarian tumours were significantly high among patients above 41 years in comparison to benign ovarian tumours of same age group (p value = 0.0008). Out of 32, ten malignant ovarian tumours occurred in relatively young age group. Of the 860 ovarian lesions, 438 and 422 ovarian lesions were removed through open technique and laparoscopic techniques respectively. Mature cystic teratoma (64.1%) was the commonest benign tumor and serous cyst adenocarcinoma (43.8%) was the commonest malignant tumour in this study. Conclusion: Ovarian tumours are one of the gynaecological diagnoses in Kathmandu University Hospital. If only ovarian neoplasms are considered, most of the ovarian tumours are benign and few are malignant. Minimal invasive surgeries are possible, except that for malignant ovarian tumours.


2013 ◽  
Vol 131 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Christine Grützmann Faustino ◽  
Maria Cristina Guerra Passarelli ◽  
Wilson Jacob-Filho

CONTEXT AND OBJECTIVESIn Brazil, few studies have investigated the prevalence of potentially inappropriate medications (PIMs) among elderly outpatients. This study aimed to determine the prevalence of PIMs prescribed for elderly outpatients, identify the PIMs most commonly involved, and investigate whether age, sex and number of medications are related to prescription of such medications.DESIGN AND SETTINGObservational descriptive study developed in the Geriatrics Service of the Central Institute of Hospital das Clínicas (HC), Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil.METHODSPrescriptions issued to 1,270 elderly patients (≥ 60 years) were gathered from a database. These prescriptions had been written by geriatricians at a tertiary-level university hospital in São Paulo, Brazil, between February and May 2008. The prescriptions were divided according to sex and age group (60-69, 70-79 and ≥ 80). The Beers criteria were used to evaluate PIMs.RESULTSMost of the sample comprised women (77%) and the mean age was 80.1 years. The mean prevalence of PIM prescriptions was 26.9%. Female sex and number of medications prescribed were associated with prescription of PIMs. The chance of having a PIM prescription was lower among patients ≥ 70 years.CONCLUSIONThe greater prevalence of PIMs was correlated with female sex. The chance of having a PIM prescription was lower among patients ≥ 70 years and became greater with increasing numbers of medications prescribed (≥ 7).


2017 ◽  
Vol 45 (5) ◽  
pp. 1553-1561 ◽  
Author(s):  
Petko Hristov Stefanovski ◽  
Radev Vladimir Radkov ◽  
Tsankov Lyubomir Ilkov ◽  
Tonchev Pencho Tonchev ◽  
Todorova Yoana Mladenova ◽  
...  

Objective To identify the demographic patterns of mortality, the time spent before death in the emergency department (ED), and the causes of fatal outcomes. Methods We performed a 5-year (01/01/2011 to 01/01/2016) retrospective analysis of all non-traumatic deaths in the ED of the UMHAT – Pleven. To extract the necessary information, we used the registers in the ED until the patients’ death. Results Among 156,848 patients in the study period, 381 died and the mortality rate was 2.4/100000. The male:female ratio was 1.48:1. The 71–80 years age group was the most affected. The mean (SD) age of patients who died in the ED was 69.9 ± 8.4 years. Most non-traumatic deaths (222 cases) were due to cardiovascular disease. Most patients (70.9%) died within 2.3 h after arrival. The factors contributing to mortality included poverty, transporting the patient to hospital too late, and a lack of developed care centres for terminally ill patients. Conclusion Most patients die within approximately 2 h after arrival at the ED. The main cause of death is acute myocardial infarction. Pulmonary embolism remains unrecognized in most patients (69%). Oncological pathology is among the main causes (7.4%) of mortality.


2008 ◽  
Vol 132 (5) ◽  
pp. 800-812
Author(s):  
Shantveer G. Uppin ◽  
C. Sundaram ◽  
Matapathi Umamahesh ◽  
P. Chandrashekar ◽  
Y. Jyotsna Rani ◽  
...  

Abstract Context.—The bones of the hands and feet constitute more than half of the bones in the human skeleton (106/ 206), but lesions occurring in them are infrequently reported. Although many of the lesions that occur in the rest of the skeletal bones can occur in bones of the hands or feet, their distribution and frequency differ. Objective.—To study lesions involving bones of the hands or feet. Design.—Retrospective study of all lesions involving bones of the hands or feet during the period from January 2000 to September 2006 from a university hospital in southern India. Clinical, radiologic, and pathologic features were reviewed. Results.—The 50 lesions encountered included 23 (46.0%) infections/inflammatory lesions, 16 (32.0%) benign tumors, 6 (12.0%) malignant tumors, and 5 (10.0%) tumorlike lesions. Giant cell tumor was the most common benign tumor. Malignant tumors involved the nonphalangeal bones, with chondrosarcoma the most common. Conclusions.—Lesions of the bones of the hands or feet are uncommon. Awareness and correlation of clinical, radiologic, and pathologic features help in making correct diagnoses.


2021 ◽  
Vol 3 (1) ◽  
pp. 01-06
Author(s):  
Aliya Ishaq ◽  
Rufina soomro ◽  
Nazia Lodhi ◽  
Muhammad Shadab Khan

Phyllodes are rare breast neoplasms with higher rate of local and systemic recurrence. This study presents the results of an audit of all cases of biopsy proven phyllodes tumor presenting to breast services in Liquat National University Hospital Karachi, Pakistan, from 1993 to 2010. Total 260 female patients were retrospectively audited, 151 had benign, 35 borderline and 74 had malignant histology. Mean follow up duration for all types was 2 years. The mean age for benign lesions was 28, for borderline 36.8 and for malignant lesions 41 years. For all histopathological types the mean tumor size was 6.2 cm. It was 5.4 cm for benign, 7.8 cm for borderline and 11.2 cm for malignant lesions. 200/260 (76.9%) patients had breast conservation while 60/260 (23.0%) had mastectomy. Histopathology type and grade has statistically significant relationship with recurrence ( p value .0001 % ) Overall recurrence rate was 20/260 (7.69%) with one patient with malignant phyllodes having recurrence 6 times despite clear margins and two patients with borderline phyllodes having recurrence twice . Tumor recurred in 2/151(1.3% ) of benign , 5.7% borderline ( 2/35 ) and 21.6% malignant ( 16/74 ) cases .Malignant group had 8 (10.8% ) systemic and 12 (16.2%)local recurrences. All patients with local recurrence and involved margins had reexcision except for 2 who had mastectomy with muscles involved posteriorly during the first surgery where re-excision was not possible. mortality rate for malignant phyllodes was 5.4 % ( 4/74 deaths as a result of systemic recurrence ) Conclusion: Phyllodes tumor is an aggressive disease, in our series, grade and type of tumor on histopathology is the significant risk factor for local and systemic recurrence with rate reaching up 21.6% for local and 10.8% for systemic recurrence in malignant lesions.


2015 ◽  
Vol 5 (3) ◽  
pp. 435-441 ◽  
Author(s):  
Laura Luukkainen ◽  
Risto Bloigu ◽  
Virpi Moilanen ◽  
Anne Marja Remes

Background: Frontotemporal lobar degeneration (FTLD) is responsible for as many as every fifth case of early-onset dementia. Very few epidemiological studies of FTLD have been conducted; there are no published epidemiological data of FTLD from Finland or the other Nordic countries. The C9ORF72 expansion-associated FTLD is common in Finland; thus, the prevalence of FTLD is expected to be high in this population. Methods: We retrospectively evaluated the incidence and prevalence of FTLD in university hospital settings in Northern Finland. Results: The mean 1-year incidence of FTLD was 5.54/100,000 (range 1.9-11.3/100,000) in the population aged 45-65 years. The prevalence of FTLD in the same age group was 20.5/100,000. Conclusion: The incidence and prevalence of FTLD in Finland seem to be the highest in Europe. However, studies from different countries may not be directly mutually comparable due to methodological issues.


2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Diallo Alpha OumaR

Introduction: The aim of this study was to determine the frequency of tracheotomies in our department over the last five (5) years, list the indications and explain the technique and postoperative follow-up. Material and Methods: This is a 5-year (January 2013-December 2017) retrospective and analytical study of the records of patients who have had tracheotomies in the ENT and Neck and Facial Surgery department of the Ignace Deen National Hospital in Conakry. Results: During this period, 48 tracheotomies were performed in the department, with a frequency of 5.42%. The mean age of our patients was 35 years with extremes of 9 years and 67 years. The age group from 10 to 19 was the most affected. The sex ratio was 1.67. All socio-professional categories were affected. The aetiologies of the air obstacle were dominated by cancerous lesions: laryngeal cancer, laryngeal papillomatosis and hypopharyngeal cancer, representing 22.92%, 20.83% and 14.58% of cases respectively. The tracheotomy was most often carried out under local anaesthesia with a supra isthmic tracheal opening in an inverted H or I shape in 77.08% of cases. Complications observed in our series were cervical emphysema and obstructive mucus plug in 6.25% of cases and 1 case of death, i.e. 2.08%. Early decanulation was performed in 41.67% of cases. Conclusion: Tracheostomy is a lifesaving procedure and commonly performed in our practice. A proper technique with carefully selected indications enables minimises the risk of complications.


2020 ◽  
Author(s):  
Hee Jin Chang ◽  
Sooyoung Kim ◽  
In-Sun Kwon ◽  
Han Young Yu ◽  
Seong-Hae Jeong

BACKGROUND Examination of eye movement both with fixation and without fixation is important in the management of patients with dizziness and imbalance. At present, a device that records eye movement without fixation usually utilizes Frenzel glasses with a desktop-based recording system. This system is inconvenient because Windows devices are large and require substantial power, and no Windows-based mobile phone exists. A mobile device application (app) could address those concerns. OBJECTIVE To assess the efficacy and feasibility of mobile app-based Frenzel tests in dizziness clinics. METHODS We performed an investigator-initiated, blinded-outcome assessor, parallel, randomized controlled crossover trial at Chungnam National University Hospital between August 2019 and October 2019. Certified medical staff were randomly assigned to the intervention group (i.e., a mobile app-based Frenzel glass system, n=15) or the observation group (i.e., a conventional desktop-based Frenzel glass system, n=15); the groups applied the respective systems for the preparation of eye movement recording and switched systems. The primary outcome was the elapsed time in seconds it took the participants to prepare the system for eye recording simulation. The secondary outcomes were perceived stress and satisfaction scores after completion of the operation, as measured by a questionnaire using ten-point Likert scales. RESULTS The mean time of machine preparation for eye recording simulation was reduced by 50% in the mobile app group compared to the desktop group in both study periods (38.0±7.1 vs. 76.0±8.7). We detected no carryover effect. Participants also reported lower stress while using app than while using the desktop system (2.3±1.3 vs. 4.6±2.4; p<0.001). The app obtained a mean overall satisfaction score of 9.2 out of 10. CONCLUSIONS The implementation of an eye movement recording app in a dizziness examination was well adopted by users and decreased the time and stress related to machine operation. CLINICALTRIAL This trial is registered with cris.nih.go.kr under number KCT 0004403.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
C. Verhaeghe ◽  
H. El Hachem ◽  
L. Inchboard ◽  
R. Corroenne ◽  
C. Dreux ◽  
...  

Abstract Background The learning curve cumulative summation test (LC CUSUM test) allows to define an individualized learning curve and determine the moment when clinical proficiency is attained. After acquisition of the skills, the cumulative summation test (CUSUM test) allows to monitor the maintenance of the required level over time. The LC CUSUM test has been frequently used in the field of Obstetrics and Gynecology (Ob/Gyn) for several procedures, but only once for OR. Methods We performed a retrospective study at Angers university hospital between May 2017 and September 2018. Seven Ob/Gyn residents and 5 senior physicians were included, and all OR performed during that time (n = 690) were analyzed. The performance index assessed was the oocyte retrieval rate (ORR), defined as the ratio of oocytes retrieved to follicles aspirated. We used the LC CUSUM test to analyze the learning curves of residents, and the CUSUM test to monitor the performance of senior physicians. An ORR ≥50% in 60% of retrievals was defined as the threshold for clinical proficiency. Results Six hundred seventy-four oocyte retrieval (OR) were included: 315 were performed by residents, 220 by senior physicians, and 139 by both residents and physicians (mixed retrievals). Four residents (57%) reached the threshold after aspirating 82, 67, 53 and 46 ovaries, respectively. The mean number of ovaries aspirated in order to reach clinical proficiency was 62, and the mean number of weeks needed was 21. The duration of the learning period varied between 26 and 80 days. Two senior physicians (40%) remained proficient across the duration of the study, while two physicians (40%) had one statistically “suboptimal” OR, and one physician (20%) had two suboptimal retrievals. Conclusion There is a large variability in the duration of the learning period and the number of procedures needed for a resident to master OR. Senior physicians maintain an adequate performance.


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