Lesions of the Bones of the Hands and Feet: A Study of 50 Cases

2008 ◽  
Vol 132 (5) ◽  
pp. 800-812
Author(s):  
Shantveer G. Uppin ◽  
C. Sundaram ◽  
Matapathi Umamahesh ◽  
P. Chandrashekar ◽  
Y. Jyotsna Rani ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Benign Tumor ◽  
Malignant Tumors ◽  
Cell Tumor ◽  
University Hospital ◽  
Benign Tumors ◽  
Inflammatory Lesions ◽  
Common Benign Tumor ◽  
Pathologic Features ◽  
Hands And Feet

Abstract Context.—The bones of the hands and feet constitute more than half of the bones in the human skeleton (106/ 206), but lesions occurring in them are infrequently reported. Although many of the lesions that occur in the rest of the skeletal bones can occur in bones of the hands or feet, their distribution and frequency differ. Objective.—To study lesions involving bones of the hands or feet. Design.—Retrospective study of all lesions involving bones of the hands or feet during the period from January 2000 to September 2006 from a university hospital in southern India. Clinical, radiologic, and pathologic features were reviewed. Results.—The 50 lesions encountered included 23 (46.0%) infections/inflammatory lesions, 16 (32.0%) benign tumors, 6 (12.0%) malignant tumors, and 5 (10.0%) tumorlike lesions. Giant cell tumor was the most common benign tumor. Malignant tumors involved the nonphalangeal bones, with chondrosarcoma the most common. Conclusions.—Lesions of the bones of the hands or feet are uncommon. Awareness and correlation of clinical, radiologic, and pathologic features help in making correct diagnoses.

scholarly journals Epidemiological and Clinicopathological Analysis of 92 Odontogenic Tumors: A 5-year Retrospective Study

2017 ◽  
Vol 18 (11) ◽  
pp. 1056-1060 ◽  
Author(s):  
Ipsita Sharma ◽  
Geetanjali Bawa ◽  
Syed Vaseemuddin ◽  
Amit Joseph ◽  
Jimmy K Sangtani
Keyword(s):  
Retrospective Study ◽  
Benign Tumor ◽  
Malignant Tumors ◽  
Oral Pathology ◽  
Odontogenic Tumors ◽  
Odontogenic Myxoma ◽  
Common Benign Tumor ◽  
Clinicopathological Analysis ◽  
Odontogenic Epithelium ◽  
Odontogenic Fibroma

ABSTRACT Introduction Odontogenic tumors (OTs) are a heterogeneous group of lesions that are derived from odontogenic apparatus comprised of odontogenic epithelium, ectomesenchyme, and/or mesenchymal elements. The OTs show marked geographical variation. This study was conducted to analyze the epidemiology and clinicopathological presentation of OTs based on age, sex, and site. Materials and methods This study was conducted in Department of Oral Pathology and Microbiology. Records were reviewed retrospectively for all the lesions of oral cavity from January 2010 to December 2015. A total of 92 lesions were found to be OTs and were classified into benign and malignant tumors. They were further subdivided into three subtypes based on the types of odontogenic tissues involved. These were epithelial OTs (EOTs), mixed OTs (MIXOTs), and mesenchymal OTs (MOTs). Results Of 92 OTs, 84 were benign (males 48, females 36) and 8 were malignant (male 2, females 6). The most common benign tumor was ameloblastoma (AME) (20), followed by keratocystic OT (KCOT) (17), calcifying EOT (CEOT) (14), compound odontome (OD-Cd) (12), complex odontome (OD-Cx) (10), odontogenic fibroma (OF) (5), odontogenic myxoma (OM) (4), and cementoblastoma (CB) (2). The most common malignant tumor was primary intraosseous squamous cell carcinoma (PIOSCC) (3) followed by fibrosarcoma (FS) (3) and ameloblastic carcinoma (AC). Conclusion Author concluded that there was geographic and demographic variation in distribution of OTs, which may be attributed to socioeconomic and genetic factors. Clinical significance Literature showing prevalence of OTs in India is negligible. By this article, we have analyzed the frequency of various OTs according to sex, age, and site. A comprehensive record of OTs should be started so that pathologists and surgeons would be able to acquire the information about the tumor for reference in the future. How to cite this article Sharma I, Venkatesh D, Bawa G, Vaseemuddin S, Joseph A, Sangtani JK. Epidemiological and Clinicopathological Analysis of 92 Odontogenic Tumors: A 5-year Retrospective Study. J Contemp Dent Pract 2017;18(11):1056-1060.

Retrospective Evaluation of Lingual Tumors in 42 Dogs: 1999–2005

2008 ◽  
Vol 44 (6) ◽  
pp. 308-319 ◽  
Author(s):  
Jason A. Syrcle ◽  
Jennifer J. Bonczynski ◽  
Sebastien Monette ◽  
Philip J. Bergman
Keyword(s):  
Prognostic Factors ◽  
Retrospective Study ◽  
Benign Tumor ◽  
Malignant Tumors ◽  
Benign Tumors ◽  
Tumor Type ◽  
Retrospective Evaluation ◽  
Short Term ◽  
Drinking Habits

In this retrospective study of 42 cases of lingual tumors in dogs, 27 (64%) were malignant, and 15 (36%) were benign. Median survival time for dogs with benign tumors was >1607 days, compared to 286 days for malignant tumors. Prognostic factors significantly associated with increased survival included complete histological margins (P=0.036), smaller tumor size (P=0.003), and benign tumor type (P=0.011). Smaller tumors were more likely to be completely resected (P=0.008) and were less likely to recur (P=0.001). Partial or subtotal glossectomies were performed in 13 cases. Short-term morbidity associated with glossectomy included ptyalism and dehiscence. Long-term morbidity included minor changes in eating and drinking habits.

scholarly journals Laryngeal Papillomatosis in Adults: Assessment for Ten Years at the ENT Department of the National University Hospital of Fann (Dakar, Senegal)

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
N. Ndour ◽  
S. Maiga ◽  
A. Houra ◽  
R. E. A. Deguenonvo ◽  
C. Ndiaye ◽  
...  
Keyword(s):  
Benign Tumor ◽  
University Hospital ◽  
Malignant Degeneration ◽  
Age Group ◽  
Laryngeal Papillomatosis ◽  
Common Benign Tumor ◽  
National University ◽  
Laryngeal Dyspnea ◽  
The Mean ◽  
The Moment

Objectives. The aim of this study was to describe the epidemiological, diagnostic, and therapeutic aspects of adult laryngeal papillomatosis in Senegal. Patients and Methods. This is a retrospective descriptive study of patients aged above 18 years with laryngeal papillomatosis and followed at the ENT department of the NUH of Fann between 01 January 2009 and 31 December 2018. Results. The mean age at diagnosis was 37.74 years and a sex ratio of 0.93. The 20–29 age group was the most represented (45.2%). The average consultation delay was 8.34 years. All patients had dysphonia at the moment of the diagnostic and in 35.5% of cases, and it was associated with laryngeal dyspnea. Glottis localization was present in all our patients, i.e., 100% of the cases. A tracheotomy was performed in 9.67% of cases. All of our patients have had their papilloma peeled per endoscopic with tweezers. No cases of malignant degeneration were found in our study. Conclusion. Laryngeal papillomatosis is the most common benign tumor of the larynx in both children and adults. Despite the progress of endoscopy and antiviral treatments, its treatment poses many problems in our undermedicalized countries.

scholarly journals Diagnostic accuracy of computed tomography to identify adenomas among adrenal incidentalomas in an endocrinological population

2018 ◽  
Vol 178 (5) ◽  
pp. 439-446 ◽  
Author(s):  
M Marty ◽  
D Gaye ◽  
P Perez ◽  
C Auder ◽  
M L Nunes ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Malignant Tumors ◽  
Correlation Coefficients ◽  
University Hospital ◽  
Benign Tumors ◽  
Adrenal Incidentalomas ◽  
Reference Standard ◽  
Quantitative Ct ◽  
Endocrine Society ◽  
Predictive Values

Context The recent recommendations of the European Endocrine Society states that the performance of computed tomography (CT) to characterize ‘true' adrenal incidentalomas (AIs) remains debatable. Objective To determine relevant thresholds for usual CT parameters for the diagnosis of benign tumors using robust reference standard among a large series of ‘true’ AIs recruited in an endocrinological setting. Design Retrospective study of 253 AIs in 233 consecutive patients explored in a single university hospital: 183 adenomas, 33 pheochromocytomas, 23 adrenocortical carcinomas, 5 other malignant tumors and 9 other benign tumors. Reference standard was histopathology in 118 AIs, biological diagnosis of pheochromocytoma in 2 AIs and size stability after at least 1 year of follow-up in 133 AIs. Methods Sensitivity, specificity and positive and negative predictive values were estimated for various thresholds of size, unenhanced attenuation (UA), relative and absolute wash-out (RPW, APW) of contrast media. 197 scans were reviewed independently in a blinded fashion by two expert radiologists to assess inter-observer reproducibility of measurements. Results Criteria associated with a 100% positive predictive value for the diagnosis of benign AI were: a combination of size and UA: 30 mm and 20 HU or 40 mm and 15 HU, respectively; RPW >53%; and APW >78%. Non-adenomatous AIs with rapid contrast wash-out were exclusively benign pseudocysts and pheochromocytomas, suggesting that classical thresholds of 60% and 40% for APW and RPW, respectively, can be safely used for patients with normal metanephrine values. Inter-observer reproducibility of all parameters was excellent (intra-class correlation coefficients: 0.96–0.99). Conclusions Our study, the largest conducted in AIs recruited in an endocrinological setting, suggests safe thresholds for quantitative CT parameters to avoid false diagnoses of benignity.

scholarly journals PEComa: A Perivascular Epithelioid Cell Tumor in the Liver—A Case Report and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Faseeh Khaja ◽  
Allison Carilli ◽  
Said Baidas ◽  
Aravindhan Sriharan ◽  
Shanedelle Norford
Keyword(s):  
Malignant Tumors ◽  
Mtor Inhibitors ◽  
Epithelioid Cell ◽  
Soft Tissue Tumors ◽  
Cell Tumor ◽  
The Body ◽  
Benign Tumors ◽  
Review Of The Literature ◽  
Perivascular Epithelioid Cell ◽  
Perivascular Epithelioid Cell Tumors

Perivascular epithelioid cell tumors are soft tissue tumors that can occur in various locations in the body whose incidence is rising. Hepatic PEComas are quite rare and diagnosis involves positivity of Melan-A and HMB45 on immunohistochemistry. Usual treatment is surgery for benign tumors and chemotherapy including mTOR inhibitors for malignant tumors. Here we discuss the radiological and pathological diagnosis, evaluation, and management of a hepatic PEComa. We describe a 51-year-old patient who was diagnosed incidentally after unusual physical exam findings.

Surgical Treatment of Primary Cardiac Tumors—Experience with 45 Patients

1995 ◽  
Vol 3 (2) ◽  
pp. 49-52
Author(s):  
Lin Jue Yi ◽  
Chu Shu Hsun ◽  
Lee Yuan Teh ◽  
Wang Shoei Shen ◽  
Lin Fang Yue ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Left Atrium ◽  
Malignant Tumors ◽  
Thyroid Tissue ◽  
University Hospital ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
Incomplete Resection ◽  
Long Term Result ◽  
Primary Cardiac Tumors

Primary cardiac tumors are very rare and the majority of them are histologically benign and surgically curable. During a 30-year period from 1963 to January 1993, 45 cases of primary cardiac tumors were surgically excised at the National Taiwan University Hospital, representing 0.52% of 8,695 open heart surgical cases during the same period. In this series, 42 cases (94%) were benign tumors; 39 (88%) were myxoma (30 female, 9 male), and 32 (82%) originated in the left atrium. None were discovered in the left ventricle. In all but the first 6 cases, tumors in patients with myxoma in the left atrium were successfully excised by the transseptal approach. There were 3 patients with rare benign tumors: intracardiac goiter, rhabdomyoma, and hemangioma respectively. The intracardiac goiter was completely excised with no ectopic thyroid tissue after operation and the other 2 received palliative resection. The latter 2 patients suffered no recurrence. Rhabdomyosarcoma, leiomyosarcoma and malignant lymphoma were noted in one patient each, all of whom died of low cardiac output in the early postoperative course. In our experience, the majority of primary cardiac tumors were benign and located in the left atrium. The long-term result of surgical treatment of benign cardiac tumors is excellent, even incases of incomplete resection, while the results from surgical treatment of malignant tumors is poor.

Sulfatides in ovarian tumors: clinicopathological correlates

2004 ◽  
Vol 14 (1) ◽  
pp. 89-93 ◽  
Author(s):  
A. M. Makhlouf ◽  
M. M. Fathalla ◽  
M. A. Zakhary ◽  
M. H. Makarem
Keyword(s):  
Malignant Tumors ◽  
Early Stage ◽  
Ovarian Tumors ◽  
University Hospital ◽  
Benign Tumors ◽  
Control Group ◽  
Tumor Type ◽  
Cross Sectional ◽  
Response To Chemotherapy ◽  
Advanced Stages

ObjectivesTo investigate the expression of sulfatides in the tissue homogenates of malignant ovarian tumors, benign ovarian tumors, and control tissues and to study the relation between this marker and other clinico-pathological criteria such as the tumor type, grade of differentiation, surgical stage and ovulatory years.DesignCross-sectional study.SettingDepartment of Obstetrics and Gynecology and Department of Biochemistry, Assuit university hospital.SubjectsForty-six patients had malignant ovarian tumors. Sixteen patients had benign ovarian neoplasm. Thirty patients, with normal ovaries, represented the control group.MethodsA sample of the tumor or from the normal ovary (the control group) was sent for histopathological and biochemical examination. Sulfatides were measured by a rapid and sensitive spectrophotometric method.ResultsThere was a significant rise in benign tumors [median and range 43 (38–53)], than in the control group, 21 (18–31), P-value = 0.000. In malignant tumors, the median value of sulfatides was significantly higher than in benign tumors [127 (71–193), P-value = 0.000]. Sulfatides were significantly higher in patients with more ovulatory years and tumors of advanced stages (stage III/IV) and poor differentiation.ConclusionsSulfatides may play a role in the pathogenesis of benign and malignant ovarian tumors. It may also predict advanced stages in patients who are apparently early stage. It is also a candidate to study of their association with response to chemotherapy.

scholarly journals An Unusual Localization of a Pleomorphic Adenoma in the Rhinopharynx

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Fabio Pagella ◽  
Francesco Chu ◽  
Alessandro Pusateri ◽  
Elina Matti
Keyword(s):  
Local Recurrence ◽  
Pleomorphic Adenoma ◽  
Benign Tumor ◽  
Histological Evaluation ◽  
Benign Tumors ◽  
Minor Salivary Glands ◽  
Upper Aerodigestive Tract ◽  
Parotid Glands ◽  
Endoscopic Evaluation ◽  
Common Benign Tumor

Pleomorphic adenoma is the most common benign tumor of the parotid glands. Rarely it may arise from minor salivary glands of the upper aerodigestive tract. A 57-year-old woman was admitted at our institution presenting with nasal obstruction. Endoscopic evaluation revealed a pedicled mass in the rhinopharynx. After radiological examination, we opted for a transnasal endoscopic-assisted excision of the mass under general anaesthesia. Histological evaluation deponed for pleomorphic adenoma with clear surgical margins. No endoscopic evidence of local recurrence has been shown after 48 months of followup. In the literature, few cases of pleomorphic adenoma arising in the rhinopharynx have been reported. The introduction of endoscopy, as shown by our experience, leads to important benefits in the identification, treatment, and followup of such rhinopharyngeal benign tumors.

Cranial Base Surgery: Results in 183 Patients

1994 ◽  
Vol 110 (6) ◽  
pp. 539-546 ◽  
Author(s):  
Iva P. Janecka ◽  
Chandranath Sen ◽  
Laligam N. Sekhar ◽  
Sai Ramasastry ◽  
Hugh D. Curtin ◽  
...  
Keyword(s):  
Skull Base ◽  
Congenital Malformations ◽  
Malignant Tumors ◽  
Benign Neoplasm ◽  
Cranial Base ◽  
Benign Tumors ◽  
Inflammatory Lesions ◽  
Duration Of Surgery ◽  
Cranial Base Surgery

OBJECTIVE: To learn about the effects of cranial base surgery. DESIGN: Cohort study with a mean follow-up of 30 months. SETTING: Population-based. PATIENTS: A consecutive sample of 183 patients who underwent cranial base surgery; 118 patients had malignant skull base tumors, the majority of which were previously treated; 50 had benign tumors; 9 had congenital malformations of the skull base; 3 had inflammatory lesions, and 3 had traumatic defects of the skull base. MAIN OUTCOME MEASURES: Disease-free Interval, overall survival, and rate of complications and functional status. INTERVENTION: Cranial base surgery was followed by radiotherapy (In previously untreated patients). RESULTS: After completion of follow-up (mean, 30 months), 30 (25.4%) patients had died of their malignant tumors and 8 (6.8%) had died of other causes. One patient (0.84%) was lost to follow-up. The overall cancer survival rate without regard to histologic type was 67% (63% with no evidence of disease). Among the patients who were treated for benign neoplasm, 72% had no evidence of disease at a mean follow-up of 39 months. The group of patients with congenital malformations and inflammatory and traumatic lesions demonstrated successful correction of their presurgical problem with skull base surgery. One patient (who had invasive aspergillosis) died of disease. The overall surgical-medical mortality rate was 2%; the complication rate was 33%, and the Kamofsky performance score was improved or unchanged after surgery in 83% of patients. The average duration of surgery, number of blood transfusions used, and length of the hospital stay were 10 hours, 3 units, and 15 days, respectively. CONCLUSIONS: Cranial base surgery is a valid surgical technique for treatment of cranial base afflictions. In this study It was found to be beneficial In controlling benign and malignant disease and to be the treatment of choice for selected congenital malformations, trauma, and inflammatory lesions.

Clinicopathologic Analysis of Chondroblastoma in Adults: A Single-Institution Case Series

2020 ◽  
pp. 106689692092779 ◽  
Author(s):  
Stefano Negri ◽  
Sintawat Wangsiricharoen ◽  
Leslie Chang ◽  
John Gross ◽  
Adam S. Levin ◽  
...  
Keyword(s):  
Benign Tumor ◽  
Adult Population ◽  
Case Series ◽  
Pathologic Features ◽  
Extensive Calcification ◽  
Rare Benign Tumor ◽  
Cartilage Cells ◽  
Hands And Feet ◽  
Histologic Changes

Chondroblastoma is a rare benign tumor of immature cartilage cells that generally occurs in an epiphyseal location of skeletally immature individuals. However, a few studies have reported cases in older patients. The purpose of this study was to evaluate the clinical, radiographic, and pathologic features of chondroblastoma in an adult population. The pathology archives of our institution were searched for cases of chondroblastoma diagnosed in patients ≥25 years of age. Of 14 patients identified, 8 were male and 6 were female with a median age of 34 years (range = 29-54 years). Most lesions occurred in short bones of hands and feet (N = 7, 50%), followed by the long tubular bones (N = 4, 28%). All demonstrated typical histologic features of chondroblastoma, but more extensive calcification, necrosis, and degenerative changes were also seen. At follow-up (median = 73.5 months), 2 patients (17%) had local recurrence. None had metastasis. In summary, chondroblastoma in adults tends to involve the short bones of the hands and feet and demonstrate histologic changes associated with long-standing growth of a benign tumor.

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