scholarly journals Pleomorphic Adenoma Presenting as an Atypical Nasal Mass in a 26-Year-Old Female

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Racheal Hapunda ◽  
Chibamba Mumba ◽  
Owen Ngalamika

Pleomorphic adenoma (PA) is a salivary gland tumor that may rarely occur in the nasal cavity. It can be a clinical diagnostic dilemma in many instances due to many possible differential diagnoses. We report the case of a 26-year-old female who presented with a 3-year history of a right nasal growth associated with ipsilateral nasal blockage, nasal pain, and rhinorrhea. Radiological image showed a mild enhancing lesion in the right nasal cavity. The patient underwent a lateral rhinotomy with wide excision of the mass. Histopathological exam was consistent with PA. Nasal PA is a rare entity and should be suspected as a diagnosis for intranasal tumors.

2016 ◽  
Vol 9 (3) ◽  
pp. 146-148
Author(s):  
Aparna Bhardwaj ◽  
Sonam Rathi

ABSTRACT Pleomorphic adenomas occurring in the nasal cavity are rarely encountered; nevertheless, there is abundance of minor seromucinous glands in that region. Most cases present with a painless, slowly progressing unilateral nasal obstruction, a nasal mass, and epistaxis. Herewith, we present an unusual case of pleomorphic adenoma arising from the lateral wall of the right nasal cavity in a 41-year-old male who complained of right nasal obstruction with no history of epistaxis. Rigid nasal endoscopy revealed a swelling continuous with right inferior concha. Computed tomography showed a well-defined, soft tissue mass in the right nasal cavity. The lesion was completely excised endoscopically. Histopathology confirmed a pleomorphic adenoma consisting of epithelial and mesenchymal elements. Wide exposure is crucial for complete excision with negative margins to achieve positive outcome and to prevent recurrence. How to cite this article Pandey AK, Bhardwaj A, Maithani T, Rathi S. Pleomorphic Adenoma of the Lateral Nasal Wall: An Unusual Entity. Clin Rhinol An Int J 2016;9(3):146-148.


Author(s):  
Deepankar Shukla ◽  
Nitin Bhola

Pleomorphic adenomas are benign tumour of the salivary glands that mostly affect the parotid gland. The tumor's "pleomorphic" form can be explained by its epithelial and connective tissue origins. Females between the ages of 30 and 50 are more likely to get the tumour. The tumour usually presents as asymptomatic swelling that progresses slowly. The majority of treatment is surgical removal of the tumour mass, with special attention paid to preserving the facial nerve. This is a case report of a 42-year-old female patient who had a pleomorphic adenoma of the submandibular gland. On the right side of the face, the patient had a slowly growing asymptomatic swelling. Pleomorphic adenoma is the commonest salivary gland tumor characterized by  diverse  histomorphological  features.  Early diagnosis and treatment plan entails thorough history taking, clinical examination, coupled with radiographic and histopathological findings.


2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Sonal S. Shah ◽  
Tamer Zayed Moustafa

Introduction. Salivary gland tumors are relatively common in the junction of the hard and soft palate area of the oral cavity. Pleomorphic adenoma is considered the most common benign salivary gland tumor in this location. Some of the rarer subtypes of this tumor may have a misleading clinical presentation. Recognition of these variants is important since long-standing pleomorphic adenomas have the potential to become malignant. Case Presentation. A healthy 24-year-old male was referred for a painless, large, slowly growing, exophytic swelling of the right hard and soft palate. Interestingly, the lesion was yellowish in color and soft to palpation, suggestive of an innocuous lipoma or cystic lesion. An incisional biopsy was performed and the diagnosis was consistent with pleomorphic adenoma with a significant adipose tissue component. The patient was referred to an oral surgeon and underwent a complete surgical excision. Upon two-year follow-up, the patient is doing well with no recurrences. Conclusion. This case highlights a rare microscopic variant of pleomorphic adenoma with altered clinical presentation that led to an erroneous clinical diagnosis. The importance of taking a biopsy for definitive diagnosis and appropriate management is reinforced.


Author(s):  
Nazia T. Sheikh ◽  
Rahil Muzaffar ◽  
Sumat UL Khurshid

The most common benign salivary gland tumor is the pleomorphic adenoma (PA). They can attain grotesque proportions and weigh several kilograms. They can cause facial disfigurement and, if untreated, could lead to airway compromise. Authors report a case of a large PA arising from the right submandibular salivary gland in a 48-year-old male. The lesion measured 9cmx8cmx5cm.


Author(s):  
Archana Arora ◽  
Karan Sharma

<p class="abstract">Pleomorphic adenomas (mixed tumors) are the most common benign tumor of the major salivary glands. In addition, they may also occur in the minor salivary glands of the hard and soft palate. Intranasal pleomorphic adenomas are unusual. We report a rare case of large sized pleomorphic adenoma arising from the nasal septum. A 42-year-old man presented with a 3 month history of multiple episodes of nasal bleeding and obstruction on right side of nose. On examination we found a non-tender firm mass extending upto the nasal vestibule which bled on probing. Computed tomographic scans revealed a mass in the right anterior nasal cavity and spur on left side. Paranasal sinuses, posterior choanae and nasopharynx were normal. An intranasal endoscopic approach was used to achieve a wide local resection along with coagulation of base and spurectomy on the left side. The mass was 2.5×2.0 cm with a broad based attachement of 1.0 cm on the nasal septum. The microscopic finding showed a lobular and duct-like structures consisting of a loose chondromyxoid stroma suggestive of a pleomorphic adenoma. Large sized nasal cavity mass with history of epistaxis and which bleeds on probing should be finally assessed under general anaesthesia. It should be excised endoscopically and subjected to histopathological examination<span lang="EN-IN">.</span></p>


2021 ◽  
Author(s):  
Basma Morsy ◽  
Eglal Moussa ◽  
Nourhan Aly ◽  
Enas Omar ◽  
Samar El Achy

Abstract BackgroundPleomorphic adenoma (PA) is the most common benign salivary gland tumor. Many factors have been implicated in the etiology of PA, one of which is genetic alteration in PLAG1 and HMGA2 genes. Few cases were reported about PAs appearing in patients with history of trauma or denture wear.Case presentationA 73-year-old female patient presented to the clinic with a gradually increasing mass that appeared two months ago in the upper left labial vestibule. The patient reported wearing a maxillary complete denture for 15 years. Clinical examination revealed a typical denture fissuratum, so surgical excision was the treatment of choice. Upon excision, a fully encapsulated mass was exposed and sent for histological and immunohistochemical analyses that confirmed a final diagnosis of PA.ConclusionThis case suggests a contributory role for trauma in the development of PA, following DNA alterations or through oxidative stress resulting from Chronic Mechanical Irritation (CMI).


2017 ◽  
Vol 10 (1) ◽  
pp. 11-13
Author(s):  
Aparna Bhardwaj ◽  
Sonam Rathi

ABSTRACT Pleomorphic adenomas occurring in the nasal cavity are rarely encountered; nevertheless, the abundance of minor seromucinous glands in that region is seen. Most cases present with a painless, slowly progressing unilateral nasal obstruction, a nasal mass, and epistaxis. Herewith, we present an unusual case of pleomorphic adenoma arising from the lateral wall of right nasal cavity in a 41-year-old male, who complained of right nasal obstruction with no history of epistaxis. Rigid nasal endoscopy revealed a swelling continuous with right inferior concha. Computed tomography showed a well-defined, soft tissue mass in the right nasal cavity. The lesion was completely excised endoscopically. Histopathology confirmed a pleomorphic adenoma consisting of epithelial and mesenchymal elements. Wide exposure is crucial for complete excision with negative margins to achieve positive outcome and to prevent recurrence. How to cite this article Pandey AK, Bhardwaj A, Maithani T, Rathi S. Pleomorphic Adenoma of the Lateral Nasal Wall: An Unusual Entity. Clin Rhinol An Int J 2017;10(1):11-13.


2016 ◽  
Vol 98 (7) ◽  
pp. e141-e142 ◽  
Author(s):  
SH Rossi ◽  
E Coveney

A de Garengeot hernia is defined as an incarcerated femoral hernia containing the vermiform appendix. We describe the case of a patient with a type 4 appendiceal diverticulum within a de Garengeot hernia and delineate valuable learning points.A 76-year-old woman presented with a 2-week history of a non-reducible painless femoral mass. Outpatient ultrasonography demonstrated a 36mm × 20mm smooth walled, multiloculated, partially cystic lesion anterior to the right inguinal ligament in keeping with an incarcerated femoral hernia. Intraoperatively, the appendix was found to be incarcerated in the sac of the femoral hernia and appendicectomy was performed. Histopathology demonstrated no evidence of inflammation in the appendix. However, an incidental appendiceal diverticulum was identified.It is widely recognised that a de Garengeot hernia may present with concomitant appendicitis, secondary to raised intraluminal pressure in the incarcerated appendix. Appendiceal diverticulosis is also believed to develop in response to raised pressure in the appendix and may therefore develop secondary to incarceration in a de Garengeot hernia. To our knowledge, only one such case has been described in the literature. A de Garengeot hernia is a rare entity, which poses significant diagnostic challenges. A high index of clinical suspicion is necessary as these hernias are at particularly high risk of perforation and so prompt surgical management is paramount.


Author(s):  
Ali ALTINDAĞ ◽  
Poyzan Bozkurt ◽  
Burak Bilecenoğlu ◽  
Kaan Orhan

This review study presents literature review and discusses the clinical significance of Adenomatoid Hyperplasia, a commonly misdiagnosed lesion. This rare entity has been seldom presented and is not well enough described in the literature. Only 15 reports with 95 cases could be attained during the online literature search using the keywords: Adenomatoid, Tumor, Hyperplasia, Minor salivary Glands. Data revealed a tendency towards the male gender. Age distribution of patients did not reveal a tendency towards a specific age group but presented a peak incidence in the 4th and 5th decades. Location data revealed a tendency towards the palate, especially the hard palate. Most of the presented cases were asymptomatic and the most common initial diagnosis made was salivary gland tumor. It was concluded that, adenomatoid hyperplasia of the oral cavity may resemble a wide range of pathologies and in order to differentiate and to achieve a correct diagnosis, histological evaluation is fundamental.


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