scholarly journals BNT162b2 Vaccination during Pregnancy Protects Both the Mother and Infant: Anti-SARS-CoV-2 S Antibodies Persistently Positive in an Infant at 6 Months of Age

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Chetna Mangat ◽  
Natasa Milosavljevic

Vaccinations are the most important intervention for controlling the ongoing coronavirus disease (COVID-19) pandemic, caused by the SARS-CoV-2 virus. BNT162b2 is an mRNA-based vaccine, which is promising and safe for use during pregnancy, as it could help prevent SARS-CoV-2 infection and its complications during pregnancy. Other vaccines, such as influenza and Tdap (tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis) vaccines, provide significant protection for babies. Recent studies have shown that COVID-19 antibodies are present in newborns at birth, owing to maternal BNT162b2 vaccination during pregnancy; however, it is currently unclear how long these antibodies could protect infants from SARS-CoV-2 infection and its complications. Herein, we present the case of a preterm baby born at 33 weeks via an emergency cesarean section owing to maternal complications. The mother had received two doses of the BNT162b2 vaccine at 22 and 26 weeks of gestation. Positive anti-SARS-CoV-2 S antibodies were detected in the infant at 2 weeks, 6 weeks, 3 months, and 6 months of age. This is the first case report in which BNT162b2 vaccination during pregnancy yielded a persistent immune response in an infant at 6 months of age. The declining anti-SARS-CoV-2 S antibody titers noted at 6 months of age emphasize the need for the vaccination of children at this age.

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Junnosuke Kimura ◽  
Kento Kawamura ◽  
Manami Minoura ◽  
Ayako Hiramoto ◽  
Yoshifumi Suga ◽  
...  

Abstract Background We report a case in which a list of high-risk pregnant women on cloud-based business communication tools was useful in formulating an anesthetic plan for unscheduled cesarean section. Case presentation A 37-year-old woman, who had been prescribed icosapentate for hypertriglyceridemia, received an antenatal anesthetic evaluation for possible cesarean delivery, and it was agreed that the anesthetic method for emergency cesarean section was general anesthesia if the surgery would take place within 7 days after the discontinuation of the drug, and regional anesthesia if it would take place any time later. Then this agreement was uploaded on the cloud-based business communication tools, and updated until she delivered her baby via unscheduled cesarean section. Conclusions A cloud-based business communication tools was useful in formulating an anesthesia plan for a patient undergoing a cesarean delivery. However, more discussion would be needed to utilize it in security.


2021 ◽  
Vol 12 (5) ◽  
pp. 309-310
Author(s):  
Elie Nkwabong ◽  
Sylvie Borassi

Hemorrhage is one of the major causes of maternal death. Main causes of APH are placenta previa, placenta abruption and uterine rupture. Rare causes of placenta abruption include marginal and velamentous umbilical cord insertions. We hereby present a case of placenta abruption due to marginal umbilical cord insertions occurring on a bipartite placenta. A 40-year-old nulliparous African woman, 35 weeks pregnant consulted for dark red pervaginal bleeding, which occurred recently. Past history was unremarkable. Her pregnancy was well followed up. A recent ultrasound scan revealed a fundal inserted placenta. Physical examination revealed a fundal height of 37 cm, no uterine activity, normal fetal heart tones and a blood-stained vulva. Our diagnosis was a mild placenta abruption. An obstetrical ultrasound carried out revealed a normal pregnancy and a retroplacental blood clot of 11mm. A safe baby was born through an emergency cesarean section which revealed a normally inserted bipartite placenta with a 10% placenta detachment located on one placenta half and two cords inserted marginally. The postoperative period was uneventful and she was discharged five days after cesarean section. This case report shows that marginal cord insertion, which can lead to placenta abruption, can be also observed on a bipartite placenta.


2017 ◽  
Vol 127 (3) ◽  
pp. 687-690 ◽  
Author(s):  
Jiro Akimoto ◽  
Kenta Nagai ◽  
Daisuke Ogasawara ◽  
Yujiro Tanaka ◽  
Hitoshi Izawa ◽  
...  

Sarcoidosis is a systemic granulomatous disease with unknown cause, which very rarely occurs exclusively in the central nervous system. The authors performed biopsy sampling of a mass that developed in the left tentorium cerebelli that appeared to be a malignant tumor. The mass was diagnosed as a sarcoid granuloma, which was confirmed with the onset of antibody reaction product against Propionibacterium acnes. Findings suggesting sarcoidosis to be an immune response to P. acnes infection have recently been reported, and they give insight for diagnosis and treatment of this disease. The authors report the possible first case that was confirmed with P. acnes infection in a meningeal lesion in solitary neurosarcoidosis.


Author(s):  
Zsofia DARADICS ◽  
Mirela Alexandra RUS ◽  
Antonia POPA ◽  
Cristian M. CRECAN ◽  
Cosmin P. PEȘTEAN ◽  
...  

The term dystocia refers to an abnormal birth and the most common cause is an abnormal alignment of the head or forelimbs in the birth canal. Usually in adult horses, acute renal failure occurs as a complication of another disease process that causes hypovolemia . Diarrhea and severe laminitis may develop in more serious cases. The aim of this case report was to present a cesarean section in the mare that evolved with renal failure and subsequent with laminitis. A nine year old Friesian mare was referred to the Veterinary teaching hospital FMV Cluj-Napoca, after a dystocia that could not be resolved conservatively.During surgery, profuse hemorrhage was noticed during the incision and suture of the uterine wall. Hypovolemia was corrected and recovery was uneventful. Two days after surgery, the mare developed acute hyposthenuric renal failure. After 3 days of intensive therapy, kidney function started to improve but the mare developed laminitis. The mare improved over a few weeks and was discharged after orthopedic shoeing. According to the author’s knowledge, this is the first case report of a cesarean section in the mare that evolved into this cascade of sequelae.


1995 ◽  
Vol 113 (6) ◽  
pp. 1033-1035
Author(s):  
Achiléa Lisboa Bittencourt ◽  
Kleber Chagas ◽  
Vânia Ayres Teixeira Calabrick

We present a case of large placental hemangioma comprising more than half of the organ and not causing feto-maternal complications. It appeared after 29 weeks of gestation. At 29 weeks an ultrasonography disclosed a normal placenta. At 35 weeks of gestation it measured 60 x 57 mm and appeared as a well delineated hypoechoic image. Delivery took place at 38 weeks by cesarean section and the child was normal.


Sign in / Sign up

Export Citation Format

Share Document