scholarly journals Comparison of Herbal Agents with Sodium Hypochlorite as Root Canal Irrigant: A Systematic Review of In Vitro Studies

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Kavalipurapu Venkata Teja ◽  
Krishnamachari Janani ◽  
Kumar Chandan Srivastava ◽  
Deepti Shrivastava ◽  
Jerry Jose ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sodium Hypochlorite ◽  
Root Canal ◽  
Research Question ◽  
In Vitro Studies ◽  
Microbial Load ◽  
Antimicrobial Efficiency ◽  
Significant Difference ◽  
Root Canal Irrigant

During endodontic treatment, eliminating microorganisms from the root canals should be considered with utmost importance. Before filling the canal, every effort should be made to ensure optimal shaping and adequate disinfection of the root canal system. This systematic review aimed to compare the efficacy of herbal agents with sodium hypochlorite (NaOCl) in reducing the microbial load while used as a root canal irrigant. The research question in the present study was to assess “Is there a significant difference in reducing microbial load comparing sodium hypochlorite (NaOCl) and herbal agents.” Electronic databases (PubMed, Scopus, and Web of Science) were searched from their start dates to November 2020 using strict inclusion and exclusion criteria and reviewed following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Only in vitro studies comparing herbal agents with NaOCl regarding antimicrobial efficiency were included. Two reviewers independently assessed the included article. 825 articles were obtained from an electronic database. Twenty papers were included for review of the full text. Eleven papers were excluded because they did not meet the inclusion criteria. Finally, nine articles were included in the systematic review. The present systematic review was at the in vitro level; therefore, the result cannot translate the exact clinical conditions. This systematic review concludes that herbal agents cannot be used as a main irrigant for canal disinfection.

scholarly journals Antibacterial effect of sodium hypochlorite gel on Enterococcus faecalis in endodontics: A systematic review

2020 ◽  
Vol 10 (1) ◽  
pp. 22-29
Author(s):  
Salma Fuad Al Nesser ◽  
Nada George Bshara ◽  
Özkan Adıgüzel
Keyword(s):  
Systematic Review ◽  
Enterococcus Faecalis ◽  
Sodium Hypochlorite ◽  
Root Canal ◽  
Antibacterial Effect ◽  
Risk Of Bias ◽  
Publication Date ◽  
Sodium Hypochlorite Solution ◽  
Root Canal Irrigant

Aim: The aim of this systematic review was to investigate the in vitro antibacterial effect of sodium hypochlorite gel on Enterococcus faecalis during root canal treatment. Methods: An electronic databases (PubMed, ScienceDirect, Google Scholar, CENTRAL, Health Advance) was performed (last updated was 1st April 2019). The reference lists of the included studies were hand-searched. Randomized in vitro studies that compared sodium hypochlorite gel to solution as a root canal irrigant were included. No limitation on publication date. Results: Out of 20741 articles, only two studies with 116 human teeth were included in this review. The studies showed 50% high risk of bias, and 50% medium risk of bias for the included studies. Both sodium hypochlorite gel and solution had some bacterial growth inhibition over E. faecalis. The heterogeneity in methodology of the included studies and the lack of high evidence led to contradictory results. However, sodium hypochlorite solution was better in enhancing the antibacterial effect according to the robust study. Conclusion: There is insufficient reliable evidence about the antibacterial effect of sodium hypochlorite gel on enterococcus faecalis. Although the robust study included in this review revealed that sodium hypochlorite gel is less efficient than the solution as a root canal irrigant, further studies are needed to consider the most effective type, concentration, duration and treatment protocols in enhancing the antibacterial effect of sodium hypochlorite. How to cite this article: Al Nesser S, Bshara N, Adıgüzel Ö. Antibacterial effect of sodium hypochlorite gel on Enterococcus faecalis in endodontics: A systematic review. Int Dent Res 2020;10(1):22-29. https://doi.org/10.5577/intdentres.2020.vol10.no1.3   Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

Effectiveness of ultrasonically activated irrigation on root canal disinfection: a systematic review of in vitro studies

2018 ◽  
Vol 22 (2) ◽  
pp. 655-670 ◽  
Author(s):  
Venkateshbabu Nagendrababu ◽  
Jayakumar Jayaraman ◽  
Anand Suresh ◽  
Senthilnayagam Kalyanasundaram ◽  
Prasanna Neelakantan
Keyword(s):  
Systematic Review ◽  
Root Canal ◽  
In Vitro Studies ◽  
Root Canal Disinfection

scholarly journals Effect of QMix irrigant in removal of smear layer in root canal system: a systematic review of in vitro studies

2020 ◽  
Vol 45 (3) ◽  
Author(s):  
Margaret Soo Yee Chia ◽  
Abhishek Parolia ◽  
Benjamin Syek Hur Lim ◽  
Jayakumar Jayaraman ◽  
Isabel Cristina Celerino de Moraes Porto
Keyword(s):  
Systematic Review ◽  
Root Canal ◽  
In Vitro Studies ◽  
Smear Layer ◽  
Canal System ◽  
System A ◽  
Root Canal System

scholarly journals Effects of Aging on the Color and Translucency of Monolithic Translucent Y-TZP Ceramics: A Systematic Review and Meta-Analysis of In Vitro Studies

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Chang-yuan Zhang ◽  
Check Agingu ◽  
James Kit Hon Tsoi ◽  
Hao Yu
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Tetragonal Zirconia ◽  
In Vitro Studies ◽  
Cochrane Library ◽  
Hydrothermal Aging ◽  
Significant Difference ◽  
Effects Of Aging ◽  
Meta Analyses

Background. Monolithic restorations made of translucent yttria-stabilized tetragonal zirconia polycrystal (Y-TZP) have become popular over the past few decades. However, whether aging affects the color and translucency of monolithic translucent Y-TZP is unclear. Objective. The aim of this systematic review and meta-analysis of in vitro studies was to evaluate the effects of aging on the color and translucency of monolithic translucent Y-TZP ceramics. Materials and Methods. This systematic review/meta-analysis was reported according to the PRISMA statement and registered in the OSF registries (https://osf.io/5qjmu). Four databases including Medline via the PubMed, Embase, and Web of Science databases and the Cochrane Library were searched using no publication year and language limits. The last search was executed on November 20, 2020. In vitro studies comparing the translucency and/or color of monolithic translucent Y-TZP ceramics before and after simulated aging were selected. Meta-analyses were performed using Review Manager software (version 5.3, Cochrane Collaboration, Oxford, UK) with random-effects models at a significance level of 0.05. A risk-of-bias assessment was also performed for the included studies. Results. Of the 188 potentially relevant studies, 13 were included in the systematic review. The hydrothermal aging duration ranged from 1 to 100 h at relatively similar temperatures (~134°C). In the general meta-analyses, the aged Y-TZP ceramics exhibited similar translucency parameter (TP), L ∗ , and b ∗ values compared with the nonaged controls ( P = .73 , P = .49 , and P = .62 , respectively). Moreover, there was a significant difference between the aged and nonaged Y-TZP ceramics in the a ∗ value ( P = .03 ; MD = − 0.26 ; 95% CI = − 0.51   to − 0.02 ), favoring the nonaged Y-TZP ceramics. The subgroup analyses showed that the duration of aging contributed to changes in the translucency and color of the Y-TZP ceramics. Conclusions. The optical properties of monolithic translucent Y-TZP ceramics were stable after hydrothermal aging at 134°C and 0.2 MPa for ≤20 h. Moreover, clinically unacceptable changes in the translucency and color of monolithic translucent Y-TZP ceramics were found after hydrothermal aging for >20 h.

scholarly journals Apical extrusion of debris with different rotary and reciprocating single-file endodontic instrumentation systems: a systematic review and meta-analysis protocol

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e038502
Author(s):  
Muhammad Zubair Ahmad ◽  
Durre Sadaf ◽  
Marcy McCall MacBain ◽  
Ahmed Nabil Mohamed
Keyword(s):  
Systematic Review ◽  
Root Canal ◽  
Ex Vivo ◽  
In Vitro Studies ◽  
Sensitivity Analyses ◽  
Endodontic Infection ◽  
Single File ◽  
Statistical Heterogeneity ◽  
Apical Extrusion

IntroductionRoot canal treatment is one of the oldest dental procedures for the treatment of endodontic infection. Extrusion of debris beyond the root apex during root canal instrumentation and subsequent persistence of pain are common complications. A systematic review of the evidence on reciprocating single-file instrumentation systems and their comparison with rotary single-file systems, with apical extrusion of debris as primary outcome, will be done through this study.Methods and analysisPublished ex vivo and in vitro studies with no language restriction will be included. We will search MEDLINE (Ovid), EMBASE (Ovid), Web of Science, Cochrane and Google Scholar. Strategies will be incorporated to search grey literature also. Thorough evaluation of search results, completion of data abstraction and assessment of quality will be done by two reviewers independent from each other. Assessment of included studies will be done by utilising an evidence model developed on the basis of standards of quality reported in guidelines to document ex vivo and in vitro studies regarding dental materials and pertained for extrusion of debris apically and has been already used in quality assessment of studies involving quantification of debris extrusion apically. We will calculate the standardised mean differences for apically extruded debris, with congruent 95% CIs. We will measure the statistical heterogeneity by applying the Cochrane Q test and quantify using the I2 statistic. Existence of covariates and any potential heterogeneity will be explored through prespecified subgroup and sensitivity analyses.Ethics and disseminationApproval from an ethical research committee is not required because it will be done using data that have been already published and have no concerns related to the privacy of patients. Extensive dissemination of results from this review will be done through submission to a peer-reviewed journal for publication and conferences.PROSPERO registration numberCRD42019151804.

scholarly journals Evaluation of 4% Sodium Hypochlorite in eliminating Enterococcus faecalis from the Root Canal when Used with Three Irrigation Methods: An in vitro Study

2017 ◽  
Vol 18 (3) ◽  
pp. 214-217
Author(s):  
Vinisha Pandey ◽  
Harsh Priyank ◽  
Abhishek Bagul ◽  
Kishore Kumar Majety ◽  
Parul Verma ◽  
...  
Keyword(s):  
Enterococcus Faecalis ◽  
Sodium Hypochlorite ◽  
Root Canal ◽  
Saline Solution ◽  
Brain Heart Infusion ◽  
Root Canals ◽  
Irrigation Methods ◽  
Group I ◽  
Significant Difference

ABSTRACT Introduction Endodontic treatment removes all pathogens, such as Enterococcus faecalis from pulp and root canals. The aim of this study is to assess the usefulness of sodium hypochlorite (NaOCl) in removing E. faecalis from the root canal used with three different irrigation methods. Materials and methods This study was conducted on freshly extracted maxillary incisors. After biomechanical preparation, root canals were injected with E. faecalis. Three groups were made which contained 30 teeth in each group; 2 mL of NaOCl solution was used for irrigation followed by agitation with K-files in group I; 2 mL of NaOCl solution was used for irrigation and ultrasonic agitation was done in group II. In group III, an alternate irrigation with NaOCl and 3% hydrogen peroxide was done. The fourth group (control) was irrigated with sterile saline solution. E. faecalis bacteria were sampled to the root canals with paper points and were transferred to tubes that contained 5 mL of brain heart infusion broth. Tubes were incubated and the presence of broth turbidity was suggestive of bacteria remaining in the root canal. Results All three groups showed no statistically significant difference. However, difference existed between experimental groups and control groups. Conclusion The author concluded that all three methods of application of NaOCl were effective in disinfecting the root canal than the saline solution. Clinical significance No single irrigant has 100% efficiency. Thus by this study, a best irrigating solution with maximum properties can be established. How to cite this article Priyank H, Pandey V, Bagul A, Majety KK, Verma P, Choudhury BK. Evaluation of 4% Sodium Hypochlorite in eliminating Enterococcus faecalis from the Root Canal when Used with Three Irrigation Methods: An in vitro Study. J Contemp Dent Pract 2017;18(3):214-217.

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