scholarly journals Combined Rothia dentocariosa and Streptococcus viridans Corneal Ulcer in an Immunocompromised Patient

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Jamie Dietze ◽  
Thomas Mauger
Keyword(s):  
Corneal Ulcer ◽  
Immunocompromised Patient ◽  
Streptococcus Viridans ◽  
Causative Organism ◽  
Common Condition ◽  
Comorbid Conditions ◽  
Conjunctival Flap ◽  
Flap Procedure ◽  
Mucous Discharge ◽  
Chemotherapy Agents

Keratitis is a very common condition seen by ophthalmologists. However, many factors can complicate the treatment of this depending on the causative organism and other patient comorbid conditions. The objective of this clinical case report is to highlight the treatment of keratitis caused by Rothia dentocariosa. It also looks at the unique considerations in keratitis presentations for patients immunocompromised by chemotherapy agents. Our patient is a 58 yo female undergoing chemotherapy with folinic acid, fluorouracil, irinotecan, and panitumumab who presented with several days of a red, painful right eye with mucous discharge. Cultures were positive for Rothia dentocariosa and Streptococcus viridans. The patient ultimately underwent a conjunctival flap procedure as medical therapy with proper oral and topical antibiotics failed to resolve keratitis. This case is unique as previously, only a couple of cases of keratitis caused by Rothia dentocariosa have been reported and none of those patients were immunocompromised nor failed antibiotic therapy.

scholarly journals TO STUDY THE CAUSATIVE ORGANISM OF CORNEAL ULCER IN A TERTIARY CARE HOSPITAL

2017 ◽  
Vol 6 (01) ◽  
pp. 42-45
Author(s):  
Keisham Sorojini Devi ◽  
Lhingkhohat Haokip ◽  
Supriya Laifangbam ◽  
Rajkumari Bhabanisana Devi
Keyword(s):  
Corneal Ulcer ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Causative Organism ◽  
Care Hospital

scholarly journals Kingella kingaeKeratitis in a Child with Underlying Vernal Keratoconjunctivitis

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Salim Nurul-Laila ◽  
Khai-Siang Chai ◽  
Ahmad Tajudin Liza-Sharmini ◽  
Ismail Shatriah
Keyword(s):  
Young Child ◽  
Young Children ◽  
Respiratory Tract ◽  
Corneal Ulcer ◽  
Vernal Keratoconjunctivitis ◽  
Causative Organism ◽  
Kingella Kingae ◽  
Corneal Scraping

Kingella kingaehad rarely been reported as a causative organism for corneal ulcer and had not been described before in vernal keratoconjunctivitis (VKC). Generally regarded as commensals of respiratory tract particularly in young children, it had however been isolated from the corneal ulcer scraping of both adult and children. We report a case of bacterial ulcer with isolation ofKingella kingaefrom the corneal scraping in a young child with underlying VKC.

scholarly journals Tegaderm transparent dressing (3M) with antibiotic ointment for treatment of infectious corneal ulcer: Antibiotic Wet Therapy

2021 ◽  
Author(s):  
Shingo Yasuda ◽  
Takayoshi Sumioka ◽  
Yukihisa Takada ◽  
Yuka Okada ◽  
Shizuya Saika
Keyword(s):  
Staphylococcus Aureus ◽  
Filamentous Fungi ◽  
Initial Treatment ◽  
Corneal Ulcer ◽  
Superficial Layer ◽  
University Hospital ◽  
Causative Organism ◽  
Gram Staining ◽  
Medical University ◽  
Antibiotic Ointment

Abstract Purpose To retrospectively review cases of infectious corneal ulcer treated with Tegaderm transparent dressing (3M) with an antibiotic ointment. Subjects and methods: A series of 29 eyes of 29 patients with possible infectious corneal keratitis were treated in Wakayama Medical University Hospital between January 1st, 2016 and December 31st, 2018. The age of the patients ranged from 26 to 92 years (mean 68.0 ± 17.8). At the first visit, the corneal infection lesion was scraped from the epithelium to the substantially superficial layer, and the scraped matter was submitted to Gram staining and culture examination. Cases suspected of fungi and Acanthamoeba were examined directly with potassium hydroxide (KOH) treatment. For several days until drug sensitivity results were obtained, initial treatment was Antibiotic Wet Therapy (AWT) with ophthalmic eye ointment and transparent Tegaderm (3M) dressing. We retrospectively reviewed the culture results of corneal scrapings (detected bacteria and drug resistance) and the therapeutic outcome of AWT. Results Nineteen eyes in which the causative bacteria were not identified and five eyes in which the causative bacteria (Pseudomonas aeruginosa, methicillin-susceptible Staphylococcus aureus (MSSA), Streptococcus, Corynebacterium.) were identified were successfully treated using AWT with ofloxacin ointment. methicillin-resistant Staphylococcus aureus (MRSA) was detected in 3 of 5 eyes in which AWT with ofloxacin was not successful, and filamentous fungi were detected in one eye. Two of the three eyes MRSA detected were healed by changing to vancomycin hydrochloride eye ointment, one of which was severely affected and was later enucleated. One eye with filamentous fungi was treated after changing to pimaricin eye ointment. A causative pathogen was not identified in the other eye, but because it was suspected to be fungal the ointment was changed to a pimaricin eye ointment, which led to healing. Conclusion AWT may be an option for initial treatment of corneal infections when the causative organism is unknown.

scholarly journals Spontaneous Corneal Hydrops in a Patient with a Corneal Ulcer

2016 ◽  
Vol 7 (1) ◽  
pp. 49-53
Author(s):  
Hatim Batawi ◽  
Nikisha Kothari ◽  
Andrew Camp ◽  
Luis Bernhard ◽  
Carol L. Karp ◽  
...  
Keyword(s):  
Severe Pain ◽  
Corneal Ulcer ◽  
Treatment Options ◽  
Corneal Edema ◽  
Slit Lamp ◽  
Study Results ◽  
Mucous Discharge ◽  
History Of ◽  
Corneal Hydrops ◽  
The Right

Purpose: We report the case of a 77-year-old man with no history of keratoconus or other ectatic disorders who presented with corneal hydrops in the setting of a corneal ulcer. The risk factors, pathogenesis and treatment options of corneal hydrops are discussed. Method: This is an observational case report study. Results: A 77-year-old man presented with a 1-day history of severe pain, redness, mucous discharge and photophobia in the right eye. A slit-lamp examination of the right eye showed an area of focal corneal edema and protrusion. Within the area of edema and protrusion, there was an infiltrate with an overlying epithelial defect consistent with an infectious corneal ulcer. The Seidel test showed no leakage, so a clinical diagnosis of corneal hydrops associated with nonperforated corneal ulcer was made. With appropriate antibiotic treatment, the corneal ulcer and hydrops both resolved over a 1-month period. Conclusion: Corneal hydrops can occur in the setting of corneal infections.

scholarly journals Chryseobacterium indologenes Keratitis: Successful Treatment of Multidrug-Resistant Strain

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Ivan J. Lee ◽  
Thomas Mauger
Keyword(s):  
Retinal Detachment ◽  
Vision Loss ◽  
Corneal Ulcer ◽  
Multidrug Resistant ◽  
Monocular Vision ◽  
Chryseobacterium Indologenes ◽  
Conjunctival Flap ◽  
History Of ◽  
Susceptibility Profiles ◽  
Multidrug Resistant Strain

A 72-year-old male with history of monocular vision with complete vision loss in his right eye from previous retinal detachment presented with 20/200 vision in the left eye with a corneal ulcer. Culture was obtained, and the patient was started on fortified tobramycin, fortified vancomycin, and amphotericin. Despite the antibiotics, the patient did not significantly improve, after which another culture was obtained before the patient was taken to the surgery for cryotherapy and a partial conjunctival flap. The culture identified Chryseobacterium indologenes. There have been fewer than a handful of cases reported in the last three decades with different antibiotic susceptibility profiles. Our patient was successfully treated with ciprofloxacin and ceftazidime with the final vision of 20/40.

scholarly journals Repositioning of pedicle conjunctival flap performed for refractory corneal ulcer

2014 ◽  
Vol 21 (1) ◽  
pp. 89 ◽  
Author(s):  
Ashok Sharma ◽  
Kanwar Mohan ◽  
Rajan Sharma ◽  
VerinderS Nirankari
Keyword(s):  
Corneal Ulcer ◽  
Conjunctival Flap

scholarly journals Use of a Reverse Thermodynamic Gel to Manage Chronic Shedding in Equine Strangles

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Mark Bowen
Keyword(s):  
Causative Organism ◽  
High Morbidity ◽  
Common Condition ◽  
Asymptomatic Carriers ◽  
Streptococcus Equi

Strangles is a common condition in equine practice with high morbidity. Management of outbreaks is complicated by the development of asymptomatic carriers with the causative organism (Streptococcus equi var equi) being retained within the guttural pouch1,2. This Bright Veterinary Idea looks at the use of a reverse thermodynamic gel to manage chronic shedding in equine strangles. 

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