Primer reporte de Chryseobacterium indologenes en costas salvadoreñas

Se informa el primer registro de Chryseobacterium indologenes en el agua circundante de la zona arrecifal del Área Natural Protegida (ANP) Complejo Los Cóbanos. La identificación se llevó a cabo mediante ensayo API 20 NE y con el empleo del software de identificación bacteriana APIWEB (bioMérieux).

Tigeciclina intraventricular como tratamiento de ventriculitis por Chryseobacterium indologenes multirresistente. A propósito de un caso pediátrico

La ventriculitis por Chryseobacterium indologenes puede ser un reto terapéutico importante, sobre todo cuando el germen adquiere resistencia intra tratamiento a los antimicrobianos habituales. La tigeciclina intraventricular podría ser una excelente opción en estos casos. Se presenta el caso de una escolar que recibió tratamiento intraventricular con tigeciclina, ante la ausencia de alternativas terapéuticas, con suceso exitoso.

Oral Abscess Caused by Chryseobacterium indologenes in Ball Python (Python regius); A Case Report

Chryseobacterium indologenes is an opportunistic pathogen isolated from human infections and, rarely, from some aquatic animals. A 3-year-old male ball python (Python regius) was admitted to the veterinary clinic by a pet owner because of acute respiratory and swallowing failure. During physical examinations, oral secretions and abscesses were observed in the mouth cavity and throat of the animal. After microbiological analysis including isolation, identification, and 16s rRNA sequencing, C. indologenes was detected as the main cause of the oral abscess in this case. Phylogenetic relatedness analysis showed a close relationship between this isolate and other strains isolated from human infections. Antimicrobial susceptibility testing revealed that the isolate was multi-drug resistant. However, it was very sensitive to minocycline, ceftazidime, and tetracycline. The patient was treated by antibiotic therapy and completely recovered after two weeks. To the best of our knowledge, this is the first incidence of C. indologenes in an oral abscess in a ball python. As a result we would consider this organism as an opportunistic animal pathogen with zoonotic potentiality.

Chryseobacterium indologenes Keratitis: Successful Treatment of Multidrug-Resistant Strain

A 72-year-old male with history of monocular vision with complete vision loss in his right eye from previous retinal detachment presented with 20/200 vision in the left eye with a corneal ulcer. Culture was obtained, and the patient was started on fortified tobramycin, fortified vancomycin, and amphotericin. Despite the antibiotics, the patient did not significantly improve, after which another culture was obtained before the patient was taken to the surgery for cryotherapy and a partial conjunctival flap. The culture identified Chryseobacterium indologenes. There have been fewer than a handful of cases reported in the last three decades with different antibiotic susceptibility profiles. Our patient was successfully treated with ciprofloxacin and ceftazidime with the final vision of 20/40.

Chryseobacterium indologenes as a Rare Pathogen of Bacteremia in Febrile Neutropenia

Chryseobacterium indologenes (C. indologenes) is nonmotile, oxidase-, and indole-positive gram-negative aerobic bacillus. Immunosuppression, comorbidities, use of broad-spectrum antibiotics are known risk factors for C. indologenes-related infections. We report a neutropenic fever caused by C. indologenes in a 16-month-old boy who was treated due to the neuroblastoma. According to the antimicrobial susceptibility test result, he was treated with cephaperazone/sulbactam.