scholarly journals Genital Mycoplasmas in Placental Infections

1994 ◽  
Vol 1 (6) ◽  
pp. 275-281 ◽  
Author(s):  
Andreas Stein ◽  
Léon Boubli ◽  
Bernard Blanc ◽  
Didier Raoult
Keyword(s):  
Genital Tract ◽  
Ureaplasma Urealyticum ◽  
Fatal Outcome ◽  
Anaerobic Bacteria ◽  
Mycoplasma Hominis ◽  
Lower Genital Tract ◽  
Bacteria And Fungi ◽  
True Infection ◽  
Aerobic And Anaerobic ◽  
Genital Mycoplasmas

Objective:The involvement of the genital mycoplasmasUreaplasma urealyticumandMycoplasma hominisin complications of pregnancy has remained controversial especially because these microorganisms are frequent colonizers of the lower genital tract. Recovery of bacteria from the placenta appears to be the sole technique to represent a true infection and not vaginal contamination. Therefore, we investigated the presence of genital mycoplasmas, aerobic and anaerobic bacteria, and fungi in human placentas and evaluated their association with morbidity and mortality of pregnancy.Methods:We cultured placentas from 82 women with complicated pregnancies. One hundred placentas from women with uncomplicated pregnancies were evaluated as controls. When possible, placentas were examined histologically for presence of chorioamnionitis.Results:Microorganisms were recovered from 52% of the placentas of complicated pregnancies andU. urealyticumwas the microorganism isolated most frequently from the placenta. A significant association between positive mycoplasma culture of the placenta and complication of pregnancy was found, and chorioamnionitis was positively related to isolation of mycoplasmas.Conclusions:These data suggest that genital mycoplasmas are able to infect the human placenta where they can cause chorioamnionitis. This infection of the placenta by genital mycoplasmas is related to preterm birth and fatal outcome of pregnancy.

scholarly journals Presence ofChlamydia, Mycoplasma, Ureaplasma,and Other Bacteria in the Upper and Lower Genital Tracts of Fertile and Infertile Populations

1993 ◽  
Vol 1 (2) ◽  
pp. 85-90
Author(s):  
Mark G. Martens ◽  
Ronald L. Young ◽  
Marco Uribe ◽  
V. C. Buttram ◽  
Sebastian Faro
Keyword(s):  
Genital Tract ◽  
Ureaplasma Urealyticum ◽  
Anaerobic Bacteria ◽  
Mycoplasma Hominis ◽  
First Trimester ◽  
Infertile Group ◽  
Work Up ◽  
Aerobic And Anaerobic ◽  
Infertile Patients ◽  
Fertile Women

Objective:The genital mycoplasmas (Mycoplasma hominisandUreaplasma urealyticum) andChlamydia trachomatishave been implicated as possible etiologic factors in infertility. Their role in patients with infertility needs to be further defined.Methods:Seventy-nine infertile patients underwent laparoscopy with cultures obtained for aerobic and anaerobic bacteria,Chlamydia, Mycoplasma,andUreaplasmafrom the peritoneal fluid, fallopian tube, endometrium, and endocervix. Cultures for similar organisms were taken from the endocervix of 80 fertile women in their first trimester. Culture results were also compared according to ovulatory status and laparoscopic findings in the infertile group.Results:There were no differences in the recovery ofUreaplasma(29% vs. 28%) orChlamydia(4% vs. 0%) positive cervical cultures in the fertile and infertile groups, respectively. However, a significantly higher number ofMycoplasmapositive cervical cultures (14% vs. 5%,P= 0.05) were found in the fertile group. Only two upper genital tract cultures were found to be positive (Ureaplasma).Conclusions:Therefore, if these organisms play a role in infertility, they are present and eradicated prior to infertility work-up and thus do not supports the use of a routine trial of antibiotics prior to laparoscopy.

Association of Genital Mycoplasmas with Exudative Vaginitis in a 10 Year Old: A Case of Misdiagnosis

PEDIATRICS ◽  
1983 ◽  
Vol 71 (2) ◽  
pp. 250-252
Author(s):  
K. B. Waites ◽  
M. B. Brown ◽  
S. Stagno ◽  
J. Schachter ◽  
S. Greenberg ◽  
...  
Keyword(s):  
Ureaplasma Urealyticum ◽  
Bacterial Pathogen ◽  
Mycoplasma Hominis ◽  
University Of Alabama ◽  
Large Numbers ◽  
Lower Genital Tract ◽  
History Of ◽  
The University ◽  
Urology Clinic ◽  
Multiple Antibiotics

A 10-year-old girl with a 1-year history of lower genitourinary tract symptoms suggestive of bacterial infection but with numerous negative urine cultures was referred to the University of Alabama urology clinic after empirical treatment with multiple antibiotics failed to resolve her symptoms. An extensive urologic evaluation revealed no structural or physiologic abnormalities, but an exudative vaginitis was noted and large numbers of Ureaplasma urealyticum and Mycoplasma hominis were isolated from the lower genital tract. Cultures for Chlamydia, viruses, and routine bacterial pathogens were negative. After initiation of tetracycline therapy, symptoms resolved and subsequent cultures for mycoplasmas were negative. In addition, a seroconversion was noted for M hominis but not for U urealyticum. Chlamydia serology was negative. It was later learned that the patient had been sexually molested just prior to the onset of symptoms. This case illustrates the necessity of early consideration of a mycoplasmal etiology in the patient with persistent genitourinary symptoms and no obvious bacterial pathogen, or in the patient whose condition is refractory to routine antibiotic therapy.

scholarly journals Prevalence and significance of Mycoplasma hominis and Ureaplasma urealyticum in the urines of a non-venereal disease population

1987 ◽  
Vol 98 (3) ◽  
pp. 353-359 ◽  
Author(s):  
Patricia M. Furr ◽  
D. Taylor-Robinson
Keyword(s):  
Healthy Volunteers ◽  
Genital Tract ◽  
Ureaplasma Urealyticum ◽  
Venereal Disease ◽  
Mycoplasma Hominis ◽  
Tract Disease

SUMMARYUreaplasma urealyticum organisms (ureaplasmas) and Mycoplasma hominis organisms (mycoplasmas) were sought in mid-stream urines collected from 200 men and 200 women attending hospital with conditions of a non-venereal nature. In addition, the urines from 100 male and 100 female healthy volunteers were examined. Overall, ureaplasmas were isolated four times more often than mycoplasmas. In individuals less than 50 years of age, the organisms were found in about 20 % of men and about 40 % of women. In individuals 50 years or older, they were found about one-third to one-half as frequently. Centrifugation of urine and examination of the resuspended deposit did not increase the isolation rates. In men, the numbers of organisms in the urine were usually small (< 103 c.c.u./ml) with less than tenfold more in the urine of women. The occurrence of 51– > 1000 leucocytes per mm3 in some of the urines was not associated with either the presence or an increased number of ureaplasmas/mycoplasmas, whereas they were associated with the presence of 105 or more bacteria/ml. The significance of these findings in the context of defining the role of ureaplasmas/mycoplasmas in genital-tract disease is discussed.

Mycoplasma and Chlamydia in Adenoids and Tonsils of Children Undergoing Adenoidectomy or Tonsillectomy

1994 ◽  
Vol 103 (2) ◽  
pp. 135-138 ◽  
Author(s):  
David Huminer ◽  
Rudi Levy ◽  
Silvio Pitlik ◽  
Zmira Samra
Keyword(s):  
Chlamydia Trachomatis ◽  
Chlamydial Infection ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Pathogenetic Role ◽  
Mycoplasma Spp ◽  
Genital Mycoplasmas

The prevalence of mycoplasmal and chlamydial infection was assessed in 83 children undergoing adenoidectomy, tonsillectomy, or both procedures for recurrent adenotonsillitis or obstructive symptoms. Throat smears (surface specimens) and minced adenoids and tonsils (core specimens) were cultured for Mycoplasma spp and for Chlamydia spp. Isolation rates in adenoidal specimens were as follows: Mycoplasma hominis, surface 7.1%, core 2.9%; and Ureaplasma urealyticum, surface 1.4%, core 2.9%. Mycoplasma hominis was also found in tonsillar specimens: surface 14.3%, core 20%. Chlamydia trachomatis was isolated only from a single core adenoidal specimen. The rate of mycoplasma isolation was significantly higher in children with recurrent adenotonsillitis (34.5%) than in those with obstructive symptoms (3.7%). Our findings document colonization of genital mycoplasmas in adenoids and tonsils of children with recurrent adenotonsillitis. Further studies are needed to evaluate the possible pathogenetic role of these microorganisms in adenotonsillar infection.

scholarly journals UROGENITAL MYCOPLASMA ROLE IN REPRODUCTIVE PATHOLOGIES

2017 ◽  
Vol 1 (65) ◽  
pp. 71-76 ◽  
Author(s):  
Ольга Островская ◽  
Olga Ostrovskaya ◽  
Марина Власова ◽  
Marina Vlasova ◽  
Ольга Кожарская ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Preterm Delivery ◽  
Detection Rate ◽  
Ureaplasma Urealyticum ◽  
Recurrent Miscarriage ◽  
Mycoplasma Hominis ◽  
Mycoplasma Genitalium ◽  
Tissue Samples ◽  
Mycoplasma Detection ◽  
Genital Mycoplasmas

The objective of the research was to study genital mycoplasma contribution to the development of reproductive disorders. Mycoplasma detection rate in genital smears of pregnant women of Khabarovsk was studied by a polymerase chain reaction (PCR) method. Ureaplasma (urealyticum+parvum) was detected in 56.3% of cases; Mycoplasma hominis in 7.5% of cases, Mycoplasma genitalium in 0% of cases. Genital mycoplasmas were detected in chorionic and fetal tissue samples in early-term spontaneous miscarriage cases, suction biopsies in women with recurrent miscarriage, tissue samples in elective abortions, placental samples of women whose pregnancy ended in preterm delivery, and placental samples of women who gave birth to children at term. Ureaplasma (urealyticum+parvum) DNA was detected in 11.9%, 18.8%, 1.4%, 32.6%, and 25.0% of cases, respectively; Mycoplasma hominis DNA in 7.4%, 12.5%, 2.6%, 2.3%, and 0% of cases, respectively; Mycoplasma genitalium DNA in 5.2%, 6.3%, 1.4%, 2.3%, 0%, respectively. Genital mycoplasmas were detected in autopsy material of children who had died in neonatal and postnatal periods. Relationship between mycoplasma concentration in vaginal flora of pregnant women and preterm delivery was identified using real-time PCR. Mycoplasma detection rate in reproductive pathologies was found to be significantly higher than in control groups. The results of the study favor the view of etiopathogenetic role of mycoplasmas in development of complications and outcomes of pregnancy.

Post-operative mediastinitis, pleuritis and pericarditis due to Mycoplasma hominis and Ureaplasma urealyticum with a fatal outcome

2008 ◽  
Vol 57 (5) ◽  
pp. 656-657 ◽  
Author(s):  
Celia García-de-la-Fuente ◽  
Eduardo Miñambres ◽  
Estibaliz Ugalde ◽  
Ana Sáez ◽  
Luis Martinez-Martinez ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Pericardial Effusion ◽  
Unusual Case ◽  
Ureaplasma Urealyticum ◽  
Fatal Outcome ◽  
Clinical Manifestations ◽  
Mycoplasma Hominis ◽  
Response To Therapy ◽  
Life Threatening ◽  
Life Threatening Complication

Post-sternotomy mediastinitis, although infrequent, is a potentially life-threatening complication of cardiac surgery. We report an unusual case of Mycoplasma hominis and Ureaplasma urealyticum post-surgical mediastinitis with persistent pleural and pericardial effusion. Clinical manifestations and response to therapy are described, and the difficulties of establishing the diagnosis are discussed.

scholarly journals Частота виявлення мікоплазм урогенітального тракту жінок у м. Дніпропетровськ

2014 ◽  
Vol 5 (1) ◽  
pp. 45-48
Author(s):  
K. V. Bubalo ◽  
L. P. Golodok ◽  
A. I. Vinnikov
Keyword(s):  
Pathogen Detection ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Culture Method ◽  
Test System ◽  
Urogenital Tract ◽  
Laboratory Diagnostics ◽  
Different Ages ◽  
Inflammatory Processes ◽  
Genital Mycoplasmas

The frequency of urogenital mycoplasmas detection in women of different ages was studied in culture with the help of DUO test-system in order to determine their etiological significance in the development of inflammatory processes of women urogenital tract. We identified the researched cultures Mycoplasma hominis, Ureaplasma urealyticum in the diagnostic titer >104 TEM/ml indicating severe contamination by microorganisms, and in the titer <103 TEM/ml, the carrier state of the identified microorganisms. Of 120 studied isolates of women urogenital tract there have been identified 113 strains of genital mycoplasmas, among which 63%  – U. urealyticum, 32% – M. hominis, 3% – microbial association of U. urealyticum – M. hominis. According to the study of frequency of detection of urogenital mycoplasma using DUO test-system culture method, it was found that the most frequently observed ones were U. urealyticum in 75 women (63%) of all individuals, M. hominis in 38 women (32%) in different diagnostic titers (>104 TEM/ml, <103 TEM/ml) in 4 women (3%) U. urealyticum – M. hominis was observed in microbial associations and mycoplasma were not found in 3 women (2%) of all surveyed patients. U. urealyticum and M. hominis in the diagnostic titer of >104 TEM/ml was observed in 55 women (46%) and 20 women (17%), respectively, and the titer of <103 CFU/ml U. urealyticum was observed in 20 women (17%), and M. hominis in 18 women (15%). Analysis of genital mycoplasmas distribution among women of different ages has shown that there was the certain correlation between the patient age and frequency of genital mycoplasmas detection: the highest detection rate was observed in women age of 24–29. The dominant pathogen of urogenital tract inflammatory processes in women in 24–29 age group is U. urealyticum. The comparison of DUO test-system and PCR data has shown that DUO test-system in culture allowed more sensitive quantitave characterization of mycoplasmas, however, for the more effective laboratory diagnostics it was necessary to use complex methods to increase the probability of pathogen detection. Incidence of mycoplasmas in women with the presence of inflammation was higher than in women having the inflammation in the genital tract. In this case, potential symptom-free carriers exist for the development of inflammation of urogenital tract of women. Scientists have proved that mycoplasma could cause vulvovaginitis, urethritis, paraurethritis, bartholinitis, adnexitis, salpingitis, endometritis, and ovaritis. 

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