scholarly journals Evidence for In Utero Hematogenous Transmission of Group B β-hemolytic Streptococcus

1994 ◽  
Vol 2 (4) ◽  
pp. 184-185 ◽  
Author(s):  
Kathleen Robischon ◽  
Marvin S. Amstey

Background: The presumed ascending route of group B β-hemolytic streptococcus (GBS) infection from the colonized maternal genital tract is well accepted. This case report proposes a hematogenous, selective infection of one unruptured amniotic sac over the other ruptured amniotic sac in a twin gestation in a patient with known GBS vaginal colonization.Case: This is a case report of GBS sepsis in twin B with intact membranes. Twin A, with 28 h of ruptured membranes, failed to show any signs of infection. The pathology of the placenta confirmed chorioamnionitis in twin B and the absence of infection in twin A.Conclusion: The presence of culture-positive GBS sepsis in the twin with the unruptured amniotic sac, as well as the absence of GBS infection in the twin with the ruptured sac, suggests an alternative means of infection for GBS infection, such as hematogenous transplacental transmission.

PEDIATRICS ◽  
1976 ◽  
Vol 58 (6) ◽  
pp. 859-861
Author(s):  
Juan B. Lopez ◽  
Paul Gross ◽  
Thomas R. Boggs

A full-term male infant delivered by caesarean section following a prolonged rupture of the amniotic membranes of 30 hours' duration manifested peculiar skin lesions at the time of birth consistent with the healing phase of bullous impetigo. He was colonized with β-hemolytic Streptococcus group B that was also cultured from the mother's cervix. It is possible this infant became infected in utero since the healing stage of the lesions suggest that they were present sometime before birth.


PEDIATRICS ◽  
1966 ◽  
Vol 38 (4) ◽  
pp. 659-661
Author(s):  
ERNEY MAHER ◽  
ROBERT C. IRWIN

A case of meningitis and septicemia due to hemolytic streptococcus group B in a 42-day-old, low birthweight infant has been presented. The increasing evidence of danger to the newborn from this organism has been discussed. The fulminant progression of the meningitic infection from initial symptoms to death leaves little hope for successful treatment. The practice of eradicating asymptomatic streptococcal B organisms from birth canals of pregnant women is proposed as a possible measure for reducing neonatal morbidity and mortality.


2019 ◽  
Vol 17 (1) ◽  
pp. 50-52
Author(s):  
Binod Kumar Mahaseth ◽  
Durga B.C.

Background: Globally, Preterm delivery is a major contributory factor for early neonatal death. Till date definite causative factor for preterm labour has not been proven. However, the genital tract infection is considered to be the contributory factors for PPROM. Method: This case control study was conducted at Nepalgunj Medical College Teaching Hospital, Kohalpur. 100 cases enrolled in the study were divided into two groups; group A consisted of 50 cases with PPROM; and in group B 50 cases were included cases without PPROM who came to routine antenatal check-up in ANC (antenatal care) clinic. The high vaginal swab was taken from the upper one-third of the posterior wall of the vagina and sent for culture and sensitivity in all cases. Results: In group A (with PPROM)74% of cases were culture positive and the commonest organism was E. coli which was isolated in 40% (20/50). In group B (without PROM) 28% of cases had culture positive, and again the commonest organism was E. coli isolated in 14 % cases (7/50). This present study showed that E. coli was most sensitive to amoxyclav and staphylococcus epidermis was most sensitive to nitrofurantoin. Ceftriaxone was found to be most effective in mixed infections. Conclusions: The genital tract infections in PPROM group was very high (+ve) culture in 74% in comparison to the non PPROM group where genital tract swab showed growth in only 28% (p-value 0.001). The lower genital tract infection has been considered as one of the potent cause of PPROM, so it is advised that a vaginal swab should be routinely obtained in the ANC clinic for culture and sensitivity. An appropriate antibiotic should be started in culture positive cases.


2021 ◽  
pp. 106689692110082
Author(s):  
Sarah Al-Rawaf ◽  
Salem Alowami ◽  
Robert Riddell ◽  
Asghar Naqvi

Russell bodies are accumulation of immunoglobulin in plasma cells forming intracytoplasmic inclusions. Russell body colitis is rare with only 3 cases described in the English literature up to date. We report a 78-year-old male with cirrhosis showing prominent cecal infiltration of Russell body containing plasma cells. Plasma cells showed no nuclear atypia or mitoses, and no evidence of light chain restriction. In this article, we report a fourth case of Russell body colitis, that is unique in being localized to the cecum in contrast to the other 3, 1 of which was in an inflammatory polyp in the sigmoid colon, 1 in a rectal tubulovillous adenoma and 1 as part of diffuse gastrointestinal disease. This is therefore the first report of localized Russell body typhlitis, occurring in a cirrhotic patient in whom an adjacent erosion was likely nonsteroidal anti-inflammatory drug-associated, a combination that may have facilitated the formation of Russell bodies.


Author(s):  
Catarina Reis-de-Carvalho ◽  
Carolina Vaz-de-Macedo ◽  
Santiago Ortiz ◽  
Anabela Colaço ◽  
Carlos Calhaz-Jorge

Abstract Introduction Malignant mesonephric tumors are uncommon in the female genital tract, and they are usually located where embryonic remnants of Wolffian ducts are detected, such as the uterine cervix. The information about these tumors, their treatment protocol, and prognosis are scarce. Case report A 60-year-old woman with postmenopausal vaginal bleeding was initially diagnosed with endometrial carcinoma. After suspicion co-testing, the patient underwent a loop electrosurgical excision of the cervix and was eventually diagnosed with mesonephric adenocarcinoma. She was subjected to a radical hysterectomy, which revealed International Federation of Gynecology and Obstetrics (FIGO) IB1 stage, and adjuvant radiotherapy. The follow-up showed no evidence of recurrence after 60 months. Conclusion We present the case of a woman with cervical mesonephric adenocarcinoma. When compared with the literature, this case had the longest clinical follow-up without evidence of recurrence, which reinforces the concept that these tumors are associated with a favorable prognosis if managed according to the guidelines defined for the treatment of patients with cervical adenocarcinomas. Though a rare entity, it should be kept in mind as a differential diagnosis for other cervical cancers.


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