scholarly journals Low Serum Uric Acid Level Is a Risk Factor for Death in Incident Hemodialysis Patients

2009 ◽  
Vol 29 (2) ◽  
pp. 79-85 ◽  
Author(s):  
S.M. Kurt Lee ◽  
Andrew L. Lee ◽  
Thomas J. Winters ◽  
Emily Tam ◽  
Mohammed Jaleel ◽  
...  
Keyword(s):  
Uric Acid ◽  
Risk Factor ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Hemodialysis Patients ◽  
Low Serum

scholarly journals Uric acid levels are critical for non-alcoholic fatty liver disease

2020 ◽  
Author(s):  
Guanqun Chao ◽  
Yue Zhu ◽  
Lizheng Fang
Keyword(s):  
Risk Factors ◽  
Uric Acid ◽  
Risk Factor ◽  
Fatty Liver ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Density Lipoprotein ◽  
Diagnostic Threshold

Abstract Background: To clarify the risk factors associated with NAFLD and further clarify the correlation between uric acid level and NAFLD by analyzing the correlation between NAFLD and different metabolic factors.Methods: Datas were obtained from subjects who underwent health examination in the Health promotion centre of Sir Run Run Shaw hospital of Zhejiang University from January 2016 to December 2017.The diagnosis of NAFLD was according to the clinical diagnosis of the Guidelines.Statistical analyses were performed using R software.Results: 79492 subjects were analyzed. 56680(71.3%) participants did not have NAFLD, 22812(28.7%) participants had NAFLD. Male, age, BMI, high blood pressure, central obesity, high glycosylated hemoglobin, high serum uric acid, high triglyceride, high total cholesterol, high low density lipoprotein cholesterol (LDL-C), abnormal liver function were risk factors of NAFLD, however, low high-density lipoprotein cholesterol (HDL-C) level was another risk factor of NAFLD.OR value suggested serum uric acid was a robust risk factor for NAFLD in all subgroups.In male group, AUC was 0.656 (95%CI: 0.651-0.661), the optimal diagnostic threshold was 395.5 mol/L, the sensitivity was 61.9%, the specificity was 61.1%, and the yoden index was 0.23. In female group, AUC was 0.716 (95%CI: 0.708-0.724), the optimal diagnostic threshold was 294.5 mol/L, sensitivity was 67.7%, specificity was 64.5%, and the Jordan index was 0.32.Conclusions: Our study suggested that there was a close correlation between serum uric acid level and NAFLD.Uric acid levels was a key risk factor for NAFLD.The diagnosis of fatty liver in patients can be preliminarily determined by detecting uric acid level.Contributions to the literature：1. The purpose of this study was to clarify the risk factors associated with NAFLD and further clarify the correlation between uric acid level and NAFLD by analyzing the correlation between NAFLD and different metabolic factors in the physical examination population.2. There was a close correlation between serum uric acid level and NAFLD.Uric acid levels was a key risk factor for NAFLD.3. The diagnosis of fatty liver in patients can be preliminarily determined by detecting uric acid level.

Serum Uric Acid Level and Cardiovascular Risks in Hemodialysis Patients: An Algerian Cohort Study

2013 ◽  
Vol 16 (17) ◽  
pp. 852-858 ◽  
Author(s):  
Adel Gouri ◽  
Aoulia Dekaken ◽  
Ahmed Aimen Bentorki ◽  
Amel Touaref ◽  
Amina Yekhlef ◽  
...  
Keyword(s):  
Uric Acid ◽  
Cohort Study ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Hemodialysis Patients ◽  
Cardiovascular Risks

scholarly journals Serum Uric Acid is Associated with Renal Prognosis of Lupus Nephritis in Women but not in Men

2020 ◽  
Vol 9 (3) ◽  
pp. 773 ◽  
Author(s):  
Tae Ryom Oh ◽  
Hong Sang Choi ◽  
Chang Seong Kim ◽  
Dong-Ryeol Ryu ◽  
Sun-Hee Park ◽  
...  
Keyword(s):  
Uric Acid ◽  
Risk Factor ◽  
Lupus Nephritis ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Lupus Erythematosus ◽  
Acid Level ◽  
Independent Risk Factor ◽  
Serum Uric Acid Level ◽  
Cox Proportional Hazards

Lupus nephritis (LN) is a major complication of systemic lupus erythematosus. Early intervention in lupus nephritis improves prognosis. There is an association between hyperuricemia and lupus nephritis; nevertheless, the sex-specific role of uric acid in lupus nephritis remains unclear. We retrospectively analyzed 578 patients diagnosed with LN by renal biopsy. We determine the relationship of serum uric acid to progression of LN using Kaplan–Meier survival analyses and Cox proportional hazards models. The primary end point was LN progression defined as the initiation of dialysis or kidney transplantation. Men had higher mean serum uric acid levels than did women. Every 1 mg/dL increase in baseline uric acid level increased the risk of LN progression by 15.1%. The serum uric acid level was an independent risk factor for LN progression in women (hazard ratio [HR], 1.158; confidence interval [CI], 1.018–1.317; p = 0.028) but not in men (HR, 1.499; CI, 0.964–2.331; p = 0.072). Sensitivity analysis involving serum uric acid terciles generated consistent and robust results. Serum uric acid level was an independent risk factor for LN progression in women but not in men.

scholarly journals Study of Serum Uric Acid Level as an Independent Risk Factor in Acute Ischemic Stroke

2020 ◽  
Vol 7 (9) ◽  
pp. 442-445
Author(s):  
Chandrashekhar K ◽  
Mohammed Anwar Hussain ◽  
Ishwar S. Hasabi ◽  
Suryakanth Suryakanth ◽  
Chethan K. Ganteppanavar
Keyword(s):  
Uric Acid ◽  
Risk Factor ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Independent Risk Factor ◽  
Serum Uric Acid Level

scholarly journals NO CORRELATION BETWEEN METABOLIC SYNDROME AND SERUM URIC ACID IN THE OFFICE WORKERS OF BUMN COMPANY IN SURABAYA

2021 ◽  
Vol 31 (1) ◽  
pp. 13
Author(s):  
Jihan Jauza Fairuz ◽  
Dewi Ratna Sari ◽  
Soebagijo Adi Soelistijo
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Uric Acid ◽  
Risk Factor ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Office Workers ◽  
Abdominal Circumference

Background: Metabolic syndrome is a cluster of risk factor which consists of central obesity, hypertriglyceride, low High Density Lipoprotein (HDL) level, hypertension, and hyperglycemia where the incidence increases among the office workers. Uric acid is often associated with cardiovascular disease while risk factor of cardiovascular disease is associated with metabolic syndrome. Objective: To analyze the correlation between metabolic syndrome and serum uric acid level in office workers. Method: This study used medical record of health examination of PT Wijaya Karya Divisi IV male office workers aged of 20 – 60 years. The data taken consisted of abdominal circumference, triglyceride level, HDL level, fasting blood glucose level, blood pressure, and serum uric acid levels. The diagnostic criterion of metabolic syndrome which was used in this study was National Cholesterol Education Program’s Adult Treatment Panel III (NCEP ATP III) that had been modified for Asian. The correlation of metabolic syndrome and serum uric acid level was analyzed by chi-square test with IBM SPSS Statistic 20 application. Results: There was no significant correlation between metabolic syndrome and serum uric acid leves in male office workers of PT Wijaya Karya Divisi IV (p=0.598). Conclusion: Among the male office workers of PT Wijaya Karya Division IV, it had no significant correlation between metabolic syndrome and serum uric acid level.

scholarly journals CORRELATION BETWEEN METABOLIC SYNDROME AND SERUM URIC ACID IN THE OFFICE WORKERS OF A BUMN COMPANY IN SURABAYA, INDONESIA

2021 ◽  
Vol 31 (1) ◽  
pp. 11
Author(s):  
Jihan Jauza Fairuz ◽  
Dewi Ratna Sari ◽  
Soebagijo Adi Soelistijo
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Uric Acid ◽  
Risk Factor ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Office Workers ◽  
Abdominal Circumference

Background: Metabolic syndrome is a cluster of risk factor which consists of central obesity, hypertriglyceride, low High Density Lipoprotein (HDL) level, hypertension, and hyperglycemia. Its incidence among the office workers is increasing. Uric acid is often associated with cardiovascular disease while risk factor of cardiovascular disease is associated with metabolic syndrome. Objective: To analyze correlation between metabolic syndrome and serum uric acid level in office workers. Materials and Methods: This study used medical record of health examination of PT Wijaya Karya Divisi IV male office workers aged of 20 – 60 years. The data taken consisted of abdominal circumference, triglyceride level, HDL level, fasting blood glucose level, blood pressure, and serum uric acid levels. The diagnostic criterion of metabolic syndrome used in this study was National Cholesterol Education Program’s Adult Treatment Panel III (NCEP ATP III) that had been modified for Asians. The correlation of metabolic syndrome and serum uric acid level was analyzed with chi-square test with IBM SPSS Statistic 20 application. Results: There was no significant correlation (p=0.598) between metabolic syndrome and serum uric acid leves in male office workers of PT Wijaya Karya Divisi IV. Conclusion: Metabolic syndrome and serum uric acid level among male office workers of PT Wijaya Karya Division IV had no correlation.

Serum Uric Acid Level as a Prognostic Marker in Patients With Acute Respiratory Distress Syndrome

2017 ◽  
Vol 34 (5) ◽  
pp. 404-410 ◽  
Author(s):  
Hyun Woo Lee ◽  
Sun Mi Choi ◽  
Jinwoo Lee ◽  
Young Sik Park ◽  
Chang-Hoon Lee ◽  
...  
Keyword(s):  
Uric Acid ◽  
Acute Respiratory Distress Syndrome ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Distress Syndrome ◽  
Serum Uric Acid Level ◽  
Acid Group ◽  
High Uric Acid ◽  
Low Serum

Purpose: Uric acid acts as both a pathogenic inflammatory mediator and an antioxidative agent. Several studies have shown that uric acid level correlates with the incidence, severity, and prognosis of pulmonary diseases. However, the association between uric acid level and acute respiratory distress syndrome (ARDS) has not been studied. This study was conducted to elucidate how serum uric acid level is related with clinical prognosis of ARDS. Methods: A retrospective cohort study with propensity score matching was conducted at a medical intensive care unit of a tertiary teaching hospital. The medical records of patients diagnosed with ARDS admitted from 2005 through 2011 were reviewed. Results: Two hundred thirty-seven patients with ARDS met the inclusion criteria. Patients with a serum uric acid level <3.0 mg/dL were classified into the low uric acid group, and those with a level ≥3 mg/dL were classified into the normal to high uric acid group. We selected 40 patients in each group using propensity score matching. A higher percentage of patients in the low uric acid group experienced clinical improvement in ARDS. More patients died from sepsis in the normal to high uric acid group. Kaplan-Meier analysis showed that a low serum uric acid level was significantly associated with better survival rate. Conclusion: In patients with ARDS, a low serum uric acid level may be a prognostic marker of a low risk of in-hospital mortality.

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