Program Studi Diploma Tiga Keperawatan, Fakultas Ilmu Kesehatan Universitas Muhammadiyah Pekajangan Pekalongan, Indonesia

Gout is a joint disease caused by high uric acid in the blood. Patients with this problem usually experience joint pain, so alternative therapies are needed to reduce pain. Ginger compress the rapyisone of the effective alternative therapies to reducepain, by utilizing warn water and greted ginger. It is paharmacological and non-pharmacological process, to reduce side effects and it is better to use non-pharmacological methods for the best result. This paper aims to find out the implication of applying the method as the alternative way to reduce pain in patientwith gout. A case study of nursing care was chosen as the method. It applied in to two patients with gout. The result stated the therapy has effectively reduced pain in the patients. Thus, it suggested to the nurses forapplying thi therapy.Keywords :gout; pain;compress with ginger AbstrakPenyakit Asam Urat atau penyakit gouta dalah penyakit sendi yang disebabkan oleh tingginya asam urat di dalam darah. Penderita Asam Urat biasanya mengalami nyeri dipersendian, sehingga diperlukan terapi alternatif untuk menurunkan nyeri. Terapi kompres jahe merupakan salah satu terapi alternative yang efektif untuk menurunkan nyeri, dengan memanfaatkan air hangat dan parutan jahe penatalaksanaan kompres jahe yaitu farmakologis dan nonfarmakologis, untuk mengurangi efek samping lebih baik menggunakan cara nonfarmakologis. Tujuan karya tulis ilmiah ini untuk menerapkan terapi kompres jahe sebagai upaya untuk menurunkan nyeri pada pasien asamurat. Metode yang digunakan dalam Karya Tulis Ilmiah ini adalah studi kasus Asuhan Keperawatan dengan penerapan terapi kompres jahe pada dua pasien Asam Urat. Hasil penerapan Kompres Jahe terbukti dapat menurunkan nyeri pada kedu apa sien Asam Urat. Untuk itu diharapkan Perawat dapat menggunakan terapi alternative kompres jahe dalam menurunkan nyeri.Kata Kunci : Asam urat,Nyeri,kompresjahe

Uric Acid Variability as a Predictive Marker of Newly Developed Cardiovascular Events in Type 2 Diabetes

Background: Cardiovascular disease (CVD) is associated with morbidity and mortality in patients with type 2 diabetes mellitus (T2D). However, the role of serum uric acid as a risk factor for developing cardiovascular disease is controversial. This study investigated whether uric acid variability was associated with new-onset symptomatic CVD in patients with T2D, requiring percutaneous coronary intervention.Methods: A total of 1,071 patients were enrolled in this retrospective cross-sectional study after propensity score matching. Patients with T2D and new-onset symptomatic CVD who received percutaneous coronary intervention for the first time, and with at least three consecutive 6-monthly measurements of serum uric acid were recruited from Severance Hospital between January 2015 and December 2019. Uric acid variability was measured by average successive variability (ASV) and analyzed to evaluate a possible correlation with the risk of developing CVD.Results: The patients were divided into quartiles based on the uric acid variability. Patients in the highest quartile were older and presented lower renal function and a higher mortality from CVD. There was a linear association between a high uric acid variability and the development of CVD. Compared to the lowest quartile, patients in the higher quartiles had a higher risk of CVD [quartile 3: adjusted odds ratio (aOR) = 1.76; 95% confidence interval (CI), 1.20–2.82; P = 0.019; quartile 4 aOR = 2.89; 95% CI, 1.74–4.80; P < 0.001].Conclusion: High uric acid variability is independently associated with an increased risk of new-onset symptomatic CVD requiring percutaneous coronary intervention in patients with T2D. Thus, maintaining serum uric acid in a narrow range by prescribing effective medications is essential to prevent new-onset CVD in patients with T2D. Nonetheless, the potential use of uric acid variability as a predictive marker of CVD in patients with T2D needs further validation.

Uric Acid Levels in Menopausal Women

Based on data from Riskesdas 2013, in line with increasing age the prevalence of joint disease has increased. The trigger is abnormal metabolic processes in the body and 10% of cases occur in postmenopausal women because the production of the hormone estrogen is disrupted. If treatment is not carried out, it will result in chronic gouty arthritis, resulting in paralysis. The purpose of this study was to determine the description of uric acid levels in postmenopausal women in Berahan Kulon Village, Wedung District, Demak Regency. The research method used is an observational study with a cross sectional approach. Of the 20 research subjects, 1 research subject had low uric acid levels, 9 research subjects had normal uric acid levels, and 10 research subjects had high uric acid levels. High uric acid levels were dominated by the age group 51-55 years, menopause duration 6-10 years and 10 years, no history of heredity, and consumption of foods high in uric acid 3-5 times/week and 5 times/week. The conclusion of this study is that 5% of postmenopausal women have low uric acid levels, 45% have normal uric acid levels, and 50% have high uric acid levels.