Effect of Increased Intracranial Pressure on Blood Pressure, Heart Rate, Respiration and Catecholamine Levels in Neonatal and Adult Rabbits

Neonatology ◽  
1987 ◽  
Vol 52 (6) ◽  
pp. 327-336 ◽  
Author(s):  
Christopher S. Ogilvy ◽  
Arthur B. DuBois
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Intracranial Pressure ◽  
Increased Intracranial Pressure ◽  
Catecholamine Levels

Surgical treatment of increased intracranial pressure

1926 ◽  
Vol 22 (3) ◽  
pp. 363
Author(s):  
I. Churaev
Keyword(s):  
Blood Pressure ◽  
Surgical Treatment ◽  
Intracranial Pressure ◽  
Brain Tumors ◽  
Endocrine Glands ◽  
Cerebral Ventricles ◽  
Increased Intracranial Pressure ◽  
Normal Relationship

Disharmony in the growth of the bones of the skull and brain, which is a consequence of a violation of the correlation of the endocrine glands, brain tumors, vascular nodes on the walls of the cerebral ventricles, and finally, a violation of the normal relationship between the blood pressure of the cranial fluid - all this can serve as the cause of increased intracranial pressure.

scholarly journals INTRAOPERATIVELY DIAGNOSED CATECHOLAMINE SECRETING MASS: A CASE REPORT.

2020 ◽  
pp. 61-62
Author(s):  
Puneet Verma
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Case Report ◽  
Pulmonary Oedema ◽  
Asymptomatic Patient ◽  
Transient Increase ◽  
High Increase ◽  
Unique Challenge ◽  
Catecholamine Levels

I hereby present a case of an asymptomatic patient whose catecholamine secreting tumor was diagnosed intraoperatively due to acute high increase in blood pressure on tumor manipulation, thought to be arising from pancreas. The fall in blood pressure was also present on removal on mass. The transient increase in catecholamines also led to pulmonary oedema which was managed accordingly. The fluctuations of blood pressure and heart rate in line with blood catecholamine levels along with other complications like arrhythmias and pulmonary oedema in such cases provide unique challenge to anesthesiologists.

scholarly journals Perbandingan Peningkatan Laju Nadi dan MAP antara Laringoskopi Menggunakan Bilah Laringoskop Macintosh dan McCoy

2019 ◽  
Vol 7 (1) ◽  
pp. 1-9
Author(s):  
Andy Hutariyus ◽  
Iwan Fuadi ◽  
Dewi Yulianti Bisri
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Test Results ◽  
Increased Intracranial Pressure ◽  
Lower Heart Rate ◽  
Randomized Controlled ◽  
St Segment ◽  
Laryngoscope Blades

Tindakan laringoskopi dan intubasi dapat menyebabkan peningkatan kadar katekolamin di dalam darah sehingga meningkatkan respons hemodinamik seperti takikardia, peningkatan tekanan darah, peningkatan tekanan intrakranial, aritmia, dan perubahan segmen ST. Respons ini bergantung pada seberapa banyak manipulasi di daerah lidah, faring, laring, dan epiglotis pada saat laringoskopi direk. Tujuan penelitian ini membandingkan peningkatan laju nadi dan mean arterial pressure (MAP) antara laringoskopi intubasi menggunakan bilah Macintosh dan McCoy. Metode penelitian ini adalah uji klinis acak terkontrol buta tunggal pada 40 pasien yang menjalani operasi dengan anestesi umum di RSUP Dr. Hasan Sadikin Bandung dari bulan Juli hingga Agustus 2018. Subjek penelitian dibagi menjadi dua kelompok, kelompok MI laringoskopi intubasi dengan Macintosh dan kelompok MC laringoskopi intubasi dengan McCoy. Data hasil penelitian diuji secara statistik menggunakan uji t tidak berpasangan dan Uji Mann-Whitney. Hasil penelitian ini menunjukkan perbedaan laju nadi dan MAP setelah intubasi pada kelompok McCoy lebih rendah dibanding dengan Macintosh pada menit ke-1, menit ke-2,5, dan menit ke-5 dengan perbedaan signifikan (p˂0,05). Simpulan penelitian ini menunjukkan bahwa laringoskopi dengan bilah laringoscop McCoy dapat mengurangi peningkatan laju nadi dan MAP dibanding dengan Macintosh.  Comparison between Laryngoscopy Using Macintosh and McCoy Laryngoscope Blades in Increasing Heart Rate and Mean Arterial PressureLaryngoscopy and intubation often increase hemodynamic responses such as tachycardia, increased blood pressure, increased intracranial pressure, arrhythmia, and changes on the ST segment due to increased blood catecholamines. This response depends on how much the tongue, pharynx, larynx, and epiglottis are manipulated during a direct laryngoscopy. This study was a single blinded randomized controlled trial on 40 patients who underwent surgery under general anesthesia in Dr. Hasan Sadikin General Hospital from July to August 2018. Subjects of study were randomly divided into two groups, Macintosh (MI) and McCoy (MC) groups. Data were analyzed using t-test and Mann-Whitney test. Results of this study found that lower heart rate and MAP increases were identified in McCoy group when compared to the Macintosh group in minute 1, minute 2,5, and minute 5 after intubation. Both variables had statistically significant differences (p<0.05). This study concludes that laryngoscopy using McCoy laryngoscope blade was is able to prevent increase in heart rate and MAP compared to Macintosh.

Changes in sympathoadrenal response to standing in humans after spaceflight

1995 ◽  
Vol 79 (2) ◽  
pp. 428-433 ◽  
Author(s):  
P. A. Whitson ◽  
J. B. Charles ◽  
W. J. Williams ◽  
N. M. Cintron
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Stroke Volume ◽  
Space Shuttle ◽  
Cardiovascular Responses ◽  
Plasma Norepinephrine ◽  
Plasma Catecholamine ◽  
Blood Samples ◽  
Before And After ◽  
Catecholamine Levels

Plasma catecholamine levels and cardiovascular responses to standing were determined in astronauts before and after several Space Shuttle missions. Blood pressure, heart rate, and cardiac output were measured and blood samples for catecholamine analyses were drawn at the end of the supine and standing periods. Supine plasma norepinephrine and epinephrine concentrations increased 34 and 65%, respectively, on landing day compared with before flight. Standing on landing day resulted in a 65 and 91% increase in plasma norepinephrine and epinephrine, respectively. Supine and standing norepinephrine levels remained elevated 3 days after landing while epinephrine levels returned to preflight levels. On landing day, supine heart rate and systolic blood pressure increased 18 and 8.9%, respectively, and standing heart rate and diastolic blood pressure were elevated by 38 and 19%, respectively. On standing, stroke volume was decreased by 26% on landing day compared with before flight. Collectively, these data indicate that the decreased orthostatic function after spaceflight results largely from the decreased stroke volume. Possible mechanisms contributing to this condition are discussed.

Comparative Study of Dexmedetomidine and Fentanyl for Attenuation of Hemodynamic Response to Laryngoscopy and Intubation

2019 ◽  
Vol 15 (3) ◽  
pp. 191-196
Author(s):  
Sabin Gauchan ◽  
Chitra Thapa
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Mean Arterial Pressure ◽  
Intracranial Pressure ◽  
Myocardial Ischemia ◽  
Arterial Pressure ◽  
Hemodynamic Response ◽  
Raised Intracranial Pressure ◽  
Group D ◽  
Fentanyl Group

Background: Laryngoscopy and intubation cause hypertension and tachycardia which can lead to myocardial ischemia or cerebrovascular hemorrhage in patients with raised intracranial pressure, hypertension. The objective of this study was to compare the efficacy of dexmedetomidine (1 mcg/kg) and fentanyl (2 mcg/kg) in attenuating hemodynamic response to laryngoscopy and intubation. Methods: Sixty patients scheduled for elective surgeries under general anaesthesia were randomly divided into two groups: Group D and Group F. Group D received dexmedetomidine 1 mcg/kg and group F received fentanyl 2 mcg/kg intravenously over 10 min prior to induction of anesthesia. All the drugs and techniques of anesthesia were standardized in patients in both the groups. Heart rate, systolic, diastolic and mean arterial pressure were recorded at following intervals: at baseline, after drug administration (at 2 and 5 min), after induction, and at 1, 2 and 5 min after intubation. Results: Heart rate and blood pressure was found to be significantly lower in dexmedetomidine group as compared to fentanyl group at 1, 2 and 5 min after intubation. Conclusions: Dexmedetomidine 1 mcg/kg is superior to fentanyl 2 mcg/kg for attenuation of hemodynamic response to laryngoscopy and intubation.

Suctioning Smarter: Answers to Eight Common Questions about Endotracheal Suctioning in Neonates

1999 ◽  
Vol 18 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Della Wrightson
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Intracranial Pressure ◽  
Tissue Damage ◽  
Endotracheal Suctioning ◽  
Airway Patency ◽  
Research Findings

ENDOTRACHEAL SUCTIONING IS important to clear secretions, maintain airway patency, and facilitate oxygenation and ventilation in intubated infants. But suctioning is not a benign procedure. It can cause hypoxia, atelectasis, pneumothorax, infection, tissue damage, and changes in heart rate, blood pressure, and intracranial pressure.1–17Studies have been conducted in both adults and infants to identify the best approach to suctioning.3,6,7,18,19This article uses research findings to address eight common questions about endotracheal suctioning. When suctioning practices are based on research, rather than on tradition, outcomes should improve.

scholarly journals Effects of the Fourth Ventricle Compression in the Regulation of the Autonomic Nervous System: A Randomized Control Trial

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Ana Paula Cardoso-de-Mello-e-Mello-Ribeiro ◽  
Cleofás Rodríguez-Blanco ◽  
Inmaculada Riquelme-Agulló ◽  
Alberto Marcos Heredia-Rizo ◽  
François Ricard ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Fourth Ventricle ◽  
Pain Treatment ◽  
Intervention Group ◽  
Control Group ◽  
Autonomic Nervous ◽  
Catecholamine Levels

Introduction. Dysfunction of the autonomic nervous system is an important factor in the development of chronic pain. Fourth ventricle compression (CV-4) has been shown to influence autonomic activity. Nevertheless, the physiological mechanisms behind these effects remain unclear.Objectives. This study is aimed at evaluating the effects of fourth ventricle compression on the autonomic nervous system.Methods. Forty healthy adults were randomly assigned to an intervention group, on whom CV-4 was performed, or to a control group, who received a placebo intervention (nontherapeutic touch on the occipital bone). In both groups, plasmatic catecholamine levels, blood pressure, and heart rate were measured before and immediately after the intervention.Results. No effects related to the intervention were found. Although a reduction of norepinephrine, systolic blood pressure, and heart rate was found after the intervention, it was not exclusive to the intervention group. In fact, only the control group showed an increment of dopamine levels after intervention.Conclusion. Fourth ventricle compression seems not to have any effect in plasmatic catecholamine levels, blood pressure, or heart rate. Further studies are needed to clarify the CV-4 physiologic mechanisms and clinical efficacy in autonomic regulation and pain treatment.

scholarly journals Manajemen Anestesi untuk Seksio Sesarea pada Pasien Eklampsia dengan Perdarahan Intrakranial

2021 ◽  
Vol 10 (2) ◽  
pp. 119-126
Author(s):  
Chrismas Gideon Bangun ◽  
◽  
Sudadi Sudadi ◽  
Siti Chasnak Saleh ◽  
◽  
...  
Keyword(s):  
Blood Pressure ◽  
Intracranial Pressure ◽  
Cesarean Section ◽  
General Anesthesia ◽  
Intracranial Hemorrhage ◽  
Rapid Sequence Induction ◽  
Fetal Distress ◽  
Definitive Treatment ◽  
Increased Intracranial Pressure ◽  
Post Surgery

Intracranial haemorrhage in pregnancy is the leading cause of death in eclampsia patients. Hypertension, which is associated with both ischemic and hemorrhagic strokes, is the main feature. Definitive treatment is termination of pregnancy with cesarean section. However, it is not appropriate to start labor in an unstable mother, despite fetal distress. Once seizures can be controlled, severe hypertension is treated and hypoxia is corrected, labor may begin. The first anesthesia management goals are seizure control, blood pressure control, and prevention of increased intracranial pressure. General anesthesia is an option in the unconscious patient, or decreased consciousness with signs of increased intracranial pressure. Anesthesia is achieved with inhalation, opioids, relaxation and hyperventilation techniques carefully. In this case a 31-year-old mother, 55 kg, 36-37 weeks' gestation comes to the hospital with a decrease in consciousness and a history of seizures. Found sensorium E2M5V2, blood pressure 180/100mmHg and proteinuria 3+. Immediately, a cesarean section with general anesthesia and rapid sequence induction with fentanyl 50 mcg, propofol 100 mg and rocuronium 50 mg intravenously were performed. Post surgery the patient was treated in the ICU, head CT-Scan was performed and intracranial hemorrhage in the right temporoparietal was encountered. Management of intracranial hemorrhage was decided conservatively. The 3rd day postoperative the patient was extubated and on the 5th day the patient was transferred with E3M5V2 sensorium.

Sedation for Nonemergent Neonatal Intubation

2001 ◽  
Vol 20 (7) ◽  
pp. 19-23 ◽  
Author(s):  
Scott DeBoer ◽  
Lisa Peterson
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Critical Care ◽  
Intracranial Pressure ◽  
Standard Of Care ◽  
Pediatric Emergency ◽  
Rapid Sequence Intubation ◽  
Rapid Sequence ◽  
Wide Awake ◽  
Neonatal Population

A newborn lies wide-awake, about to be intubated. The infant is able to feel everything, to hear everything—but cannot do anything to change the situation. Big people hold down the newborn and place a laryngoscope blade into the mouth, then a large endotracheal tube into the trachea. As the baby struggles, coughs, chokes, gags, and cries, blood pressure and intracranial pressure increase dramatically, and the heart rate plummets.Infants, like adults, do feel pain and anxiety. Yet recent studies show that NICU staff continue neonatal intubation utilizing only force. In pediatric emergency/critical care settings, rapid-sequence intubation (RSI), once confined to the environment of the operating room, is now the standard of care. An understanding of commonly administered RSI medications is essential to bring this practice to standard use in the NICU as well.In the pediatric and adult critical care population, rapidsequence intubation (RSI)—the use of sedatives and chemical paralytics to facilitate tracheal intubation—is considered the standard of care. Use of these medications optimizes intubating conditions and helps to minimize the adverse physiologic effects of intubation. Neonatology has yet to embrace this trend, however. This article addresses the issue of sedation for intubation in the neonatal population.

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