Determinants of the Partition of Renal Ammonia Production between Urine and Venous Blood in Man with Metabolic Acid-Base Disturbances

Experiments were carried out to study blood acid-base equilibrium in the cat during experiments with artificial ventilation. Blood acid-base equilibrium was examined in the arterial and venous blood by analyzing pH, carbon dioxide and oxygen partial pressure, and plasma bicarbonates. Artificial ventilation was regulated on the basis of this analysis; CO2 concentration in expired air was monitored throughout the experiment. An attempt was made to verify if artificial ventilation could be regulated indirectly only on the basis of CO2 concentration in expired air. The most appropriate acid-base equilibrium was maintained when CO2 concentration in expired air was kept within the range of 3.9-4.1%.

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Influence of changes in cardiac output on the acid-base status of arterial and mixed venous blood

Pflügers Archiv - European Journal of Physiology ◽

10.1007/bf00580274 ◽

1987 ◽

Vol 410 (3) ◽

pp. 257-262 ◽

Cited By ~ 2

Author(s):

Y. L. Hoogeveen ◽

J. P. Zock ◽

P. Rispens ◽

W. G. Zijlstra

Keyword(s):

Cardiac Output ◽

Venous Blood ◽

Mixed Venous Blood ◽

Acid Base ◽

Acid Base Status ◽

Mixed Venous

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Arterial and Mixed Venous Blood Acid-Base Balance During Hypoperfusion With Incremental Positive End-Expiratory Pressure in the Pig

Anesthesia & Analgesia ◽

10.1213/00000539-199111000-00012 ◽

1991 ◽

Vol 73 (5) ◽

pp. 576???582 ◽

Cited By ~ 2

Author(s):

A. B. Johan Groeneveld ◽

Cornelis G. Vermeij ◽

Lambertus G. Thijs

Keyword(s):

Venous Blood ◽

Mixed Venous Blood ◽

Positive End Expiratory Pressure ◽

Acid Base Balance ◽

Acid Base ◽

Base Balance ◽

Mixed Venous

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Clinical assessment of acid-base balance in Netherland Dwarf rabbit

Brazilian Journal of Biology ◽

10.1590/1519-6984.219754 ◽

2020 ◽

Author(s):

J. M. Chapel ◽

J. L. Benedito ◽

J. Hernández ◽

P. Famigli-Bergamini ◽

C. Castillo

Keyword(s):

Reference Values ◽

Venous Blood ◽

Meat Production ◽

Acid Base Balance ◽

Acid Base ◽

Sodium Potassium ◽

Mean Values ◽

Base Balance ◽

Biochemical Profiles ◽

Made In

Abstract Pet rabbits have increased their popularity in a lot of countries. However, most of the laboratory profiles in rabbit medicine come from the observations made in rabbit as biomodels or meat production. So that further researches are necessary to obtain reference values for hematology and biochemical profiles in pet rabbits and the different breeds, especially, in relation to acid-base balance. The aim of this report was to offer the mean values of the main parameters connected with acid-base profile in Netherland Dwarf breed. Thirty-five healthy rabbits (15 males and 20 females) were studied. Venous blood sample from lateral saphenous vein was analyzed to measure: haematocrit, haemoglobin, blood urea nitrogen, glucose, blood pH, partial pressure of CO2 (pCO2), total CO2, ions bicarbonate, chloride, sodium, potassium, base excess and anion Gap. Results showed a shorter range that those reported by different researchers. Moreover, differences between genders were showed in pCO2, its values were higher in males. It may be associated with a greater cellular metabolism. Values obtained in this research should be taken into account by veterinary clinicians for this breed in their clinical assessments. Besides, these values provide new results in parameters with few reference values.

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Effects of a new intravenous electrolyte solution for veterinary therapy on the electrolyte and acid-base balances of healthy horses

Ciência Rural ◽

10.1590/0103-8478cr20150741 ◽

2016 ◽

Vol 46 (8) ◽

pp. 1479-1485 ◽

Cited By ~ 2

Author(s):

Priscilla Fajardo Valente Pereira ◽

José Antonio Bessegatto ◽

Gabriela de Castro Bregadioli ◽

Stéfany Lia Oliveira Camilo ◽

Nathali Adrielli Agassi de Sales ◽

...

Keyword(s):

Electrolyte Solution ◽

Fluid Therapy ◽

Repeated Measures ◽

Venous Blood ◽

Isotonic Saline ◽

Acid Base Balance ◽

Acid Base ◽

Before And After ◽

Base Balance ◽

Clinical Changes

ABSTRACT: The effects of a new intravenous electrolyte solution for veterinary therapy on electrolyte and acid-base balances of horses were evaluated, assessing the potential of the use of this solution as a rational alternative in fluid therapy. Eight healthy adult horses, including 4 males and 4 females, received two treatments in a cross-over design: isotonic saline solution (IS) and a test solution (TS) containing 145mEq of Na+, 5mEq of K+, 4mEq of Ca++, 2mEq of Mg++, 96mEq of Cl-, 60mEq of lactate, 50g of dextrose, and 4mg of cyanocobalamin per liter. Solutions were IV infused in a volume corresponding to 5% of BW, over 3 hours. Venous blood samples were taken 5 times before and after the infusion (at 0, 3, 6, 9 e 24h), for pHv, pCO2v, HCO3 -v, BEv, Na+, K+, Cl-, Ca++, Ca, P, Mg, glucose and L-lactate measurements, and AG and SID calculations. The data were analyzed through repeated measures ANOVA. The IS caused mild acidifying effect by increasing Cl- and decreasing plasma SID. In contrast, the TS induced mild and transient hypochloremia without changes in acid-base balance. Hyperglycemia was present at the end of the TS infusion and reversed 6 hours later. The horses did not exhibit any clinical changes. We concluded that TS is an option for fluid therapy in horses.

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Effects of Acute Acid–Base Alterations on Glutamine Metabolism and Renal Ammoniagenesis in the Dog

Clinical Science ◽

10.1042/cs0540503 ◽

1978 ◽

Vol 54 (5) ◽

pp. 503-508 ◽

Cited By ~ 1

Author(s):

A. Fine ◽

F. I. Bennett ◽

G. A. O. Alleyne

Keyword(s):

Blood Flow ◽

Hydrochloric Acid ◽

Renal Blood Flow ◽

Glutamine Metabolism ◽

Ammonia Production ◽

Renal Cells ◽

Acid Base ◽

Production Of Ammonia

1. The effects of acute acid—base alterations on renal ammonia production and glutamine metabolism were studied in anaesthetized dogs. 2. Plasma glutamine rose with acidosis and also when both Pco2 and plasma HCO−3 were raised isohydrically. 3. Blood urea fell when acidosis was induced with hydrochloric acid. 4. The renal production of ammonia per ml of renal blood flow was increased in acidosis, but this was independent of the amount of glutamine delivered to the kidney. 5. The results indicate that acute acidosis affects production of urea and glutamine and increases the capacity of the renal cells to extract glutamine from blood.

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