scholarly journals Uropathogens and Gestational Outcomes of Urinary Tract Infections in Pregnancies that Necessitate Hospitalization

2019 ◽  
Vol 13 (2) ◽  
pp. 70-73 ◽  
Author(s):  
Alp Tuna Beksac ◽  
Gokcen Orgul ◽  
Atakan Tanacan ◽  
Hasan Uckan ◽  
Banu Sancak ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Urine Analysis ◽  
Klebsiella Pneumonia ◽  
Medical Treatments ◽  
Maternal Risk ◽  
Antimicrobial Susceptibility Tests ◽  
Gestational Week ◽  
Susceptibility Tests ◽  
Tract Infections

Background and Objectives: Our aim is to identify uropathogens that cause urinary tract infections (UTIs) that necessitate hospitalization, and analyze outcomes of gestational UTIs. Methods: This study consisted of 30 pregnant women who necessitate hospitalization because of UTI (7.8% of gestational UTIs during the same period of time). UTI that necessitates hospitalization is defined as clinical complaints, urination problems, urine analysis and culture positivity, fever and uterine discomfort. Patients with at least two positive cultures (≥ 100,000 cfu/ml) were included to this study. Antimicrobial susceptibility tests were obtained in all cases in order to determine antimicrobial resistance and to choose the ideal antibiotics for treatment. Results: In our study, we have found that Escherichia coli is the most common microorganism (56.7%). Enterococcus faecalis (13.3%) and Klebsiella pneumonia (10%) were other frequently observed microorganisms. In this series, mean gestational week at birth was 35 weeks 5 days (range 23-40 weeks). Mean birthweight was 2,656 g (range 500-3,700 g). Twenty-three cases (76.7%) were hospitalized before 37th gestational week and preterm delivery rate was 56.3%. Maternal risk factors and coexisting diseases were detected in 11 (36.7%) patients as follows: diabetes mellitus in 4, thrombophilia in 3, thyroid disorders in 3 and hydroureteronephrosis in 1 case. Cesarean section rate was 65.2%. Conclusions: Knowing uropathogens of patient population is beneficial in the management of patients and better planning of future medical treatments. Preterm labor seems to be an important complication in pregnancies with UTIs going together with fever and urination problems.

scholarly journals Diversity of plasmids inStaphylococcus saprophyticusisolated from urinary tract infections in women

1989 ◽  
Vol 102 (3) ◽  
pp. 413-419 ◽  
Author(s):  
J.A.G. Melo Cristino ◽  
A. Torres Pereira ◽  
L.G. Andrade
Keyword(s):  
Urinary Tract ◽  
Nalidixic Acid ◽  
Urinary Tract Infections ◽  
Antimicrobial Susceptibility ◽  
Cadmium Chloride ◽  
Antimicrobial Agents ◽  
Plasmid Analysis ◽  
Antimicrobial Susceptibility Tests ◽  
Susceptibility Tests ◽  
Tract Infections

SUMMARYA group of 150Staphylococcus saprophyticusstrains isolated from urinary tract infections in women were included in this study. Antimicrobial susceptibility tests showed that these isolates were sensitive to most antimicrobial agents. All strains were sensitive to penicillin. cephalothin. gentamicin. kanamvcin. trimethoprim and nitrofurantoin. Resistance to tetracycline was present in 10·6% of the strains. to chioramphenicol in 4 % to erythromycin in 1·3% and to streptomvcin in 1·3% All strains were resistant to cadmium chloride as well as to novobioein and nalidixic acid. Plasmid analysis showed that 8·2 % of the strains harboured plasmids, some of them with complex plasmid profiles.

scholarly journals Bacterial Causes and their Antimicrobial Susceptibility Testing among Urinary Tract Infection Patients in Tobruk Area, Libya

2021 ◽  
Vol 36 (4) ◽  
pp. 253-262
Author(s):  
Mohammed T. Mostafa ◽  
Khalid S. Mustafa ◽  
Brijesh Kumar
Keyword(s):  
Urinary Tract ◽  
Antimicrobial Susceptibility ◽  
Medical Center ◽  
Laboratory Diagnosis ◽  
Antimicrobial Susceptibility Tests ◽  
Amoxicillin Clavulanic Acid ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Tests ◽  
The Right ◽  
Tract Infections

Urinary tract infections are very common among people of all ages, but the disease is more prevalent in women, so proper clinical and laboratory diagnosis, and the right treatment are very important to avoid complications and antimicrobial resistance. This study aimed to determine the bacterial causes and antibiotic susceptibility patterns of UTI patients. Recorded results of 6065 urine sample cultures and their antimicrobial susceptibility tests from the Department of Microbiology in Tobruk Medical Center, Tobruk City, were obtained from September 2016 to December 2018. The data was analyzed and discussed in compare with other studies. The study showed that a UTI is more common in females (78.8%) compared with male patients (21.2%). Gram-negative bacteria accounted for the majority of urinary pathogens (90%), where E. coli alone was (58.4%), klebsiellae (17.4%), Proteus (10.7%), while Pseudomonas species was the least common (3.3%) of the total. While the Gram-positive bacteria S. aureus constituted 9.6% of the total. The study was found statistically significant (P=0.000). The most effective antibiotics against all uropathogens were Imipenem and Amikacin, and less effective antibiotics were Ampicillin and Amoxicillin-clavulanic acid. This study concluded that the most common cause of UTI in Tobruk was Escherichia coli and the most effective antibiotics appear to be Imipenem and Amikacin.

scholarly journals Evaluation of Risk Factors for Catheter-Related Urinary Tract Infections Caused by Carbapenem-Resistant Klebsiella pneumonia

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S147-S147
Author(s):  
Cigdem Ataman Hatipoglu ◽  
Cemal Bulut ◽  
Sebnem Erdinc ◽  
Gunay Ertem ◽  
Sami Kinikli ◽  
...  
Keyword(s):  
Risk Factors ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Klebsiella Pneumonia ◽  
Carbapenem Resistant ◽  
Tract Infections

ID: 29: INVASIVE LIVER ABSCESS SYNDROME IN NORTH AMERICA

2016 ◽  
Vol 64 (4) ◽  
pp. 938.2-939
Author(s):  
A Al-khazraji ◽  
H Alkhawam ◽  
B Garrido
Keyword(s):  
Urinary Tract ◽  
Liver Abscess ◽  
Urinary Tract Infections ◽  
Pyogenic Liver Abscess ◽  
Medical Attention ◽  
Klebsiella Pneumonia ◽  
Ct Guided ◽  
Western Countries ◽  
The Past ◽  
Tract Infections

Case presentationThis is a 25 years old Pilipino male with no past medical history who presented with fever, rigors, fatigue and night sweats for 3 days. His symptoms progressively getting worse which made him seek medical attention. Patient travelled to Philippines five months ago which he stayed for a month.Upon presentation, patient was febrile with Temp 104 F and tachycardic 139 BPM, BP113/76. He appeared to be diaphoretic and tachypnic on physical exam. Abdomen was soft and non-tender, no hepatomegaly or splenomegaly on palpation.Pertinent laboratory findings included leukocytosis of 14,000 and bandemia 12, lactate of 3.6, Liver function tests – AST 62/ALT 61/ ALK 52 GGT 48 LDH 347 Total bilirubin 2.5 and direct Bilirubin 1.6 – Hepatitis serology revealed immunity against Hepatitis B (HBV). Coagulation panel and renal function were normal. Abdominal imaging revealed diffuse hepatic changes suggestive of cirrhosis and complex avascular slightly lobulated hypoechoic mass with mild posterior enhancement measuring 7.2×6.8 cm noted in the anteromedial portion of posterior segment of the right lobe (figure 1A and B).Further tests including HIV testing, urine analysis, blood and urine cultures, Echinococcosis and Amoebic serology were none revealing. Empirical broad spectrum antibiotics with 3rd generation cephalosporin and metronidazole for possible amoebic verus pyogenic liver abscess.After 3–4 days from admission date, he developed persistent rigors, tachycardia, and appeared to have respiratory distress which required an urgent intubation for acute respiratory failure and transferred to ICU. Urgent drainage attempted for pyogenic liver abscess. Abscess fluid culture was positive for Klebsiella pneumonia.Patient received an intravenous ceftriaxone 2 gm daily with continuous Jackson-Pratt liver drain suction for 3–4 weeks which was curative with resolution and decrease in the size of liver abscess on repeat imaging (figure 1c).DiscussionKlebsiella pneumoniae, a member of the Enterobacteriaceae family, is a pathogen with worldwide distribution. Most community-acquired Klebsilla pneumoniae infections cause pneumonia or urinary tract infections. Invasive liver abscess syndrome is very rare in western countries. For the past 2 decades, a distinct clinical syndrome has been emerging in Southeast Asia that is characterized by bacteremia, liver abscesses, and metastatic infections. In the past decade, few patients were diagnosed as having a liver abscess caused by K pneumoniae in two case series in the USA.Most community-acquired Klebsilla pneumoniae infections cause pneumonia or urinary tract infections. Invasive liver abscess syndrome is very rare in western countries. Clinicians should be aware about invasive klebsiella pneumonia liver abscess especially in patients with Asian background presented with liver abscess failed the treatment with antibiotics. Treatment of invasive klebsiella pneumonia liver abscess requires dual approach medical and surgical as we approached our patient which he subsequently improved after CT-guided liver abscess drainage and four weeks of antibiotics therapy.Abstract ID: 29 Figure 1

scholarly journals Biochemical Changes and Risk Factors in the Prognosis of Antibiotics Susceptibility in Urinary Tract Infections

2019 ◽  
Vol 70 (5) ◽  
pp. 1822-1825
Author(s):  
Andrei Vata ◽  
Ioana Maria Hunea ◽  
Olivia Dorneanu ◽  
Ioana Alina Harja-Alexa ◽  
Claudia Plesca ◽  
...  
Keyword(s):  
Risk Factors ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Gram Negative Bacteria ◽  
Klebsiella Species ◽  
Resistance Patterns ◽  
Antibiotics Susceptibility ◽  
Susceptibility Tests ◽  
Tract Infections ◽  
Prognostic Risk Factors

The aim of our study was evaluation of prevalence of uncomplicated and complicated urinary tract infections (UTIs) among patients with UTIs associated with Gram - negative bacteria and analysis of prognostic risk factors in complicated UTIs. Weretrospectivelyanalyzed the medical records of inpatients with diagnosis of UTI based on clinical, biological and microbiological assay. Susceptibility tests for different antimicrobial categories were performed. Risk factors in complicated UTIs were correlated with pathogens� susceptibility. A total of 96 eligible patients were analyzed. Complicated UTIs were identified in 66.67% cases. The most frequent uropathogens isolated were E.coli and Klebsiella species. Exrtrarenal factors and nephropathic disease were the most common factors associatedwith an increased prevalence of multi -drug resistant isolates. Knowledge of the spectrum of the possible pathogens and local resistance patterns are very important for the antibacterial treatment outcome.

scholarly journals Point-Counterpoint: Reflex Cultures Reduce Laboratory Workload and Improve Antimicrobial Stewardship in Patients Suspected of Having Urinary Tract Infections

2015 ◽  
Vol 54 (2) ◽  
pp. 254-258 ◽  
Author(s):  
Romney M. Humphries ◽  
Jennifer Dien Bard
Keyword(s):  
Urinary Tract ◽  
Los Angeles ◽  
Urinary Tract Infections ◽  
Antimicrobial Stewardship ◽  
Urine Analysis ◽  
Urine Culture ◽  
Outpatient Setting ◽  
Clinical Encounters ◽  
Performing Culture ◽  
Tract Infections

Urinary tract infections (UTIs) are frequent and lead to a large number of clinical encounters. A common management strategy for patients suspected of having a urinary tract infection is to test for pyuria and bacteria by urine analysis (UA) of midstream urine, with initiation of antibiotic therapy and urine culture if one or both tests are positive. Although this practice was first used in an outpatient setting with midstream urine samples, some institutions allow its use in the management of catheterized patients. The ideas behind the reflex urine culture are to limit laboratory workload by not performing culture on negative specimens and to improve antimicrobial stewardship by not giving antimicrobials to patients with negative UA results. The questions are, first, whether reflex urine culture reduces workloads significantly and, second, whether it improves antimicrobial stewardship in the era of increasing numbers of urinary tract infections due to extensively drug-resistant Gram-negative bacilli. Romney Humphries from UCLA supports the idea that reflex urine cultures are of value and describes what reflex parameters are most useful, while Jennifer Dien Bard of Children's Hospital Los Angeles discusses their limitations.

scholarly journals Microbes and antibiotic susceptibility patterns of urinary tract infections in toilet-trained Children at a Tertiary Care Hospital of Sialkot, Pakistan.

2021 ◽  
Vol 28 (01) ◽  
pp. 22-26
Author(s):  
Syed Muhammad Hassan Akhtar ◽  
Abdul Sattar ◽  
Wajiha Rizwan ◽  
Naeem Ahmed Cheema ◽  
Aftab Anwar
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Rural Areas ◽  
Urine Analysis ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Care Hospital ◽  
Amoxicillin Clavulanate ◽  
Tract Infections

Objective: To find out various types of microorganisms causing urinary tract infections and their antibiotic sensitivity patterns among toilet-trained children presenting at a tertiary care hospital of Sialkot District. Study Design: Descriptive study. Setting: Department of Microbiology/Urology, Khawaja Muhammad Safdar Medical College, Sialkot. Period: June to December 2019. Material & Methods: A total of 176 toilet trained children, aged 7 to 15 years, presenting in outpatient department and having culture positive urinary tract infections were enrolled. Demographic information like age, gender and area of residence along with clinical findings, antibiotic sensitivities and resistance patterns were recorded. Mid-stream urine sample was collected from all toilet-trained children and immediately sent to institutional laboratory for urine analysis and urine culture and sensitivities. Results: Out of a total of 176 children, 95 (54.0%) were female and 81 (46.0%) male. Overall mean age was noted to be 10.68+2.42 years while most of the children, 94 (53.4%) were above 10 years of age. Majority of the patients, 98 (55.7%) belonged to rural areas. Eschericia coli were the most common isolate, found among 140 (79.5%) children. Imipenem (98.9%), meropenem (98.9%), piperacillin tazobactam (97.7%), fosfomycin (96.6%), amikacin (95.5%), nitrofurantoin (84.4%), gentamycin (90.9%) and amoxicillin clavulanate (83%) were found to have the highest sensitivities. Conclusion: Eschericia coli were the most common bacterial urinary pathogens in toilet-trained children. Amoxicillin clavulanate, Nitrofurantoin and Fosfomycin available in oral form showed good sensitivity of 83%, 84.4%, and 96.6% respectively) to commonly found microorganisms. It was also noted that resistance to commonly used antibiotics in our region is rising.

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