scholarly journals Diagnosis of Mixed Adenoneuroendocrine Carcinoma (MANEC) after Neoadjuvant Chemotherapy for Pancreatic and Gastric Adenocarcinoma: Two Case Reports and a Review of the Literature

2019 ◽  
Vol 12 (2) ◽  
pp. 434-442 ◽  
Author(s):  
Ester Oneda ◽  
Barbara Liserre ◽  
Denise Bianchi ◽  
Luigina Rota ◽  
Giordano  Savelli ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Gastric Adenocarcinoma ◽  
Prognostic Value ◽  
Case Reports ◽  
Low Frequency ◽  
Controversial Issues ◽  
Review Of The Literature ◽  
Mixed Adenoneuroendocrine Carcinoma ◽  
Endocrine Differentiation ◽  
Adenocarcinoma Cells

Mixed adenoneuroendocrine carcinoma (MANEC) is a rare tumor of the gastrointestinal tract involving both epithelial and neuroendocrine (NE) components, each of which represents at least 30% of the tumor. Because of the low frequency of this histotype, only a few cases have been described. In this report we discuss two cases treated with neoadjuvant chemotherapy: a pancreatic adenocarcinoma and a gastric adenocarcinoma. The histopathological specimens examined after surgery showed an additional NE component with a possible indication of the MANEC histotype. We hypothesize two possible explanations: tumor NE cells are more chemo-resistant than adenocarcinoma cells, and cytotoxic injury induces NE differentiation in tumor cells. The clinical significance and prognostic value of endocrine differentiation, however, remain controversial issues.

scholarly journals The Prognostic Value of Postoperative Lymph Node Ratio in Gastric Adenocarcinoma Patients Treated With Neoadjuvant Chemotherapy

Cureus ◽  
2021 ◽  
Author(s):  
Abdullah Sakin ◽  
Muhammed M Atci ◽  
Mehmet Naci Aldemir ◽  
Baran Akagündüz ◽  
Suleyman Şahin ◽  
...  
Keyword(s):  
Lymph Node ◽  
Neoadjuvant Chemotherapy ◽  
Gastric Adenocarcinoma ◽  
Prognostic Value ◽  
Lymph Node Ratio ◽  
Node Ratio

Fermented Wheat Grain Products and Kochujang Inhibit the Growth of AGS Human Gastric Adenocarcinoma Cells

2005 ◽  
Vol 10 (4) ◽  
pp. 349-352 ◽  
Author(s):  
Su-Ok Kim ◽  
Chang-Suk Kong ◽  
Jeung-Ha Kil ◽  
Ji-Young Kim ◽  
Min-Soo Han ◽  
...  
Keyword(s):  
Gastric Adenocarcinoma ◽  
Wheat Grain ◽  
Adenocarcinoma Cells ◽  
Human Gastric Adenocarcinoma ◽  
Grain Products

Testosterone and Breast Cancer in Transmen: Case Reports, Review of the Literature, and Clinical Observation

2019 ◽  
Vol 19 (2) ◽  
pp. e271-e275 ◽  
Author(s):  
Sara Tanini ◽  
Alessandra D. Fisher ◽  
Icro Meattini ◽  
Simonetta Bianchi ◽  
Jiska Ristori ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Observation ◽  
Case Reports ◽  
Review Of The Literature

Prenatal diagnosis of fibular aplasia‐tibial campomelia‐oligosyndactyly syndrome: Two case reports and review of the literature

2020 ◽  
Author(s):  
Márcia Marinho ◽  
Sara Nunes ◽  
Cátia Lourenço ◽  
Mónica Melo ◽  
Cristina Godinho ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Case Reports ◽  
Review Of The Literature

scholarly journals Digital Glomus Tumor: Bibliographic Review of the Studies Published over the Past 10 Years

2021 ◽  
Vol 49 (01) ◽  
pp. 046-055
Author(s):  
Victoria Hernández ◽  
Tania Lena ◽  
Eliana Camacho ◽  
Matías Craviotto
Keyword(s):  
Glomus Tumor ◽  
Case Reports ◽  
Low Frequency ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Glomus Tumors ◽  
The Past ◽  
Pubmed Search ◽  
Magnetic Resonance Imaging Mri

AbstractGlomus tumors are a mostly benign neoplasm that constitutes less than 4% of upper-limb soft-tissue tumors. Its unspecific clinical presentation, added to its low frequency, leads to a late diagnosis.The objective of the present study is to update the clinical-paraclinical approach and the surgical technique used in the treatment.We carried out a literature review from 2014 to 2019 on digital glomus tumor in the hand in adult patients using the PubMed search engine.In most of the publications analyzed, the diagnosis was clinical, with a delay of 1 to 10 years. Plain radiography is the most requested study; of the 16 articles reporting its indication, only half evidenced compatible changes. Magnetic resonance imaging (MRI) was requested in 15 articles, presenting normal results in 3 of them. The treatment of choice was surgical excision using a transungual approach. Only 4 articles report recurrence after excision.Although there is diversity in the approach to these tumors, we conclude that the diagnosis is clinical, and the treatment surgical, and there is no consensus regarding the paraclinical indication. The information available comes mainly from case reports, publications that contribute to the generation of evidence for the clinical practice in rare diseases such as this one.

Heat‐killed Helicobacter pylori upregulates NKG2D ligands expression on gastric adenocarcinoma cells via Toll‐like receptor 4

Helicobacter ◽  
2021 ◽  
Author(s):  
Carolina Hernández ◽  
Karen Toledo‐Stuardo ◽  
Paulina García‐González ◽  
Macarena Garrido‐Tapia ◽  
Karina Kramm ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Adenocarcinoma ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Nkg2d Ligands ◽  
Adenocarcinoma Cells
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