scholarly journals Review of the Literature on the Occurrence of Delirium after Veno-Venous and Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review

2019 ◽  
Vol 9 (3) ◽  
pp. 374-380
Author(s):  
Sabina Krupa ◽  
Dorota Ozga
Keyword(s):  
Systematic Review ◽  
Extracorporeal Membrane Oxygenation ◽  
Cochrane Collaboration ◽  
Risk Of Bias ◽  
Review Of The Literature ◽  
Exchange Method ◽  
Membrane Oxygenation ◽  
Extracorporeal Gas Exchange ◽  
The Subject ◽  
Ecmo Therapy

Introduction: Extracorporeal membrane oxygenation (ECMO) is an extracorporeal gas exchange method which, despite a number of advantages, carries the risk of many complications. ECMO is a modern intensive care method which in many cases is the last resort for the patient. Care and supervision are provided by a multidisciplinary team of specialists: physicians, perfusionists, and nurses. The aim of this review is to analyze the occurrence of delirium in ECMO patients. Methods: Both authors independently extracted data from all included trials and assessed the risk of bias. A systematic review was performed using the protocol of the Cochrane Collaboration Risk of Bias tool. The search was based on PubMed, Web of Science, and Mendeley. Three articles from recent years have been analyzed in this work. Literature selection was made using the PRISMA checklist. The analyzed literature proves how important the topic of delirium is in ECMO therapy. In the case of pharmacotherapy, there are many combinations of drugs that prevent the occurrence of the delirium phenomenon. Results: This work deals with the subject of delirium after ECMO, which is not a common subject in the popular literature. Many of the elements mentioned in the articles analyzed show how important this topic is. The authors place great emphasis on the elements which are not related to pharmacotherapy and the prevention of delirium. For the prevention of delirium after ECMO, a psychological approach to the patient is important. As far as pharmacotherapy is concerned, it is the last element to be taken into account in the prevention of delirium in ECMO patients. An overview of the literature indicates that the subject of nursing care has been omitted; however, there are tools which allow nurses to assess delirium in patients. Conclusion: Delirium in patients undergoing ECMO therapy is a topic that has not been fully described in the literature. This review of the literature shows how important it is to treat a patient with delirium during this therapy and how important it may be to have an early diagnosis of delirium to prevent complications.

scholarly journals Transportation of patients on extracorporeal membrane oxygenation: a tertiary medical center experience and systematic review of the literature

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Pedro Vitale Mendes ◽  
Cesar de Albuquerque Gallo ◽  
Bruno Adler Maccagnan Pinheiro Besen ◽  
Adriana Sayuri Hirota ◽  
Raquel de Oliveira Nardi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Extracorporeal Membrane Oxygenation ◽  
Medical Center ◽  
Transportation Of Patients ◽  
Review Of The Literature ◽  
Membrane Oxygenation

Life-threatening idiopathic reaction to hydrochlorothiazide treated with veno-venous extracorporeal membrane oxygenation

Perfusion ◽  
2017 ◽  
Vol 33 (4) ◽  
pp. 320-322 ◽  
Author(s):  
Sean P. Kane ◽  
Elliott Cohen
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Distress Syndrome ◽  
Severe Reaction ◽  
Review Of The Literature ◽  
Membrane Oxygenation ◽  
First Case ◽  
Immune Mediated ◽  
Life Threatening ◽  
Ecmo Therapy ◽  
Vv Ecmo

Hydrochlorothiazide has been shown to cause rare, but serious non-cardiogenic pulmonary edema. We present a case report of a patient with apparent septic shock and acute respiratory distress syndrome (ARDS) requiring life-sustaining veno-venous extracorporeal membrane oxygenation (VV-ECMO). Upon further review of the literature and the chronology of the patient’s presentation, her condition was most likely due to an immune-mediated reaction to hydrochlorothiazide. This represents the first case, to our knowledge, of such a severe reaction to hydrochlorothiazide supported with ECMO therapy.

scholarly journals Impact of Vibration on the Levels of Biomarkers: A Systematic Review

2021 ◽  
pp. 030157422110195
Author(s):  
Ashish Agrawal ◽  
TM Chou
Keyword(s):  
Systematic Review ◽  
Web Of Science ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Cochrane Collaboration ◽  
Risk Of Bias ◽  
Cochrane Library ◽  
Inclusion Criteria ◽  
Electronic Search ◽  
Proquest Dissertation

Introduction: The objective of this systematic review is to assess the effect of vibrational force on biomarkers for orthodontic tooth movement. Methods: An electronic search was conducted for relevant studies (up to December 31, 2020) on the following databases: Pubmed, Google scholar, Web of Science, Cochrane Library, Wiley Library, and ProQuest Dissertation Abstracts and Thesis database. Hand searching of selected orthodontic journals was also undertaken. The selected studies were assessed for the risk of bias in Cochrane collaboration risk of bias tool. The “traffic plot” and “weighted plot” risk of bias distribution are designed in the RoB 2 tool. The 2 authors extracted the data and analyzed it. Results: Six studies fulfilled the inclusion criteria. The risks of biases were high for 4, low and some concern for other 2 studies. The biomarkers, medium, device, frequency and duration of device, as well as other data were extracted. The outcomes of the studies were found to be heterogenous. Conclusion: One study showed highly statistically significant levels of IL-1 beta with <.001. Rate of tooth movement was correlated with levels of released biomarkers under the influence of vibrational force in 3 studies, but it was found to be significant only in 1 study. It was further observed that vibration does not have any significant reduction in pain and discomfort.

scholarly journals The effect of dietary phytochemicals on nuclear factor erythroid 2-related factor 2 (Nrf2) activation: a systematic review of human intervention trials

2021 ◽  
Author(s):  
Tom Clifford ◽  
Jarred P. Acton ◽  
Stuart P. Cocksedge ◽  
Kelly A. Bowden Davies ◽  
Stephen J. Bailey
Keyword(s):  
Systematic Review ◽  
Assessment Tool ◽  
Cochrane Collaboration ◽  
Risk Of Bias ◽  
Related Factor ◽  
Human Intervention ◽  
Nrf2 Activation ◽  
Dietary Phytochemicals ◽  
Intervention Trials

AbstractWe conducted a systematic review of human trials examining the effects of dietary phytochemicals on Nrf2 activation. In accordance with the PRISMA guidelines, Medline, Embase and CAB abstracts were searched for articles from inception until March 2020. Studies in adult humans that measured Nrf2 activation (gene or protein expression changes) following ingestion of a phytochemical, either alone or in combination were included. The study was pre-registered on the Prospero database (Registration Number: CRD42020176121). Twenty-nine full-texts were retrieved and reviewed for analysis; of these, eighteen were included in the systematic review. Most of the included participants were healthy, obese or type 2 diabetics. Study quality was assessed using the Cochrane Collaboration Risk of Bias Assessment tool. Twelve different compounds were examined in the included studies: curcumin, resveratrol and sulforaphane were the most common (n = 3 each). Approximately half of the studies reported increases in Nrf2 activation (n = 10); however, many were of poor quality and had an unclear or high risk of bias. There is currently limited evidence that phytochemicals activate Nrf2 in humans. Well controlled human intervention trials are needed to corroborate the findings from in vitro and animal studies.

scholarly journals Chronic respiratory disease and survival outcomes after extracorporeal membrane oxygenation

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Tak Kyu Oh ◽  
Hyoung-Won Cho ◽  
Hun-Taek Lee ◽  
In-Ae Song
Keyword(s):  
Respiratory Failure ◽  
Extracorporeal Membrane Oxygenation ◽  
Lung Disease ◽  
Respiratory Disease ◽  
Chronic Respiratory Disease ◽  
Newly Diagnosed ◽  
Membrane Oxygenation ◽  
Obstructive Sleep ◽  
All Cause Mortality ◽  
Ecmo Therapy

Abstract Background Quality of life following extracorporeal membrane oxygenation (ECMO) therapy is an important health issue. We aimed to describe the characteristics of patients who developed chronic respiratory disease (CRD) following ECMO therapy, and investigate the association between newly diagnosed post-ECMO CRDs and 5-year all-cause mortality among ECMO survivors. Methods We analyzed data from the National Health Insurance Service in South Korea. All adult patients who underwent ECMO therapy in the intensive care unit between 2006 and 2014 were included. ECMO survivors were defined as those who survived for 365 days after ECMO therapy. Chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, lung cancer, lung disease due to external agents, obstructive sleep apnea, and lung tuberculosis were considered as CRDs. Results A total of 3055 ECMO survivors were included, and 345 (11.3%) were newly diagnosed with CRDs 365 days after ECMO therapy. The prevalence of asthma was the highest at 6.1% (185). In the multivariate logistic regression, ECMO survivors who underwent ECMO therapy for acute respiratory distress syndrome (ARDS) or respiratory failure had a 2.00-fold increase in post-ECMO CRD (95% confidence interval [CI]: 1.39 to 2.89; P < 0.001). In the multivariate Cox regression, newly diagnosed post-ECMO CRD was associated with a 1.47-fold (95% CI: 1.17 to 1.86; P = 0.001) higher 5-year all-cause mortality. Conclusions At 12 months after ECMO therapy, 11.3% of ECMO survivors were newly diagnosed with CRDs. Patients who underwent ECMO therapy for ARDS or respiratory failure were associated with a higher incidence of newly diagnosed post-ECMO CRD compared to those who underwent ECMO for other causes. Additionally, post-ECMO CRDs were associated with a higher 5-year all-cause mortality. Our results suggest that ECMO survivors with newly diagnosed post-ECMO CRD might be a high-risk group requiring dedicated interventions.

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