scholarly journals Sexual Dysfunction in Postmenopausal Women with Breast Cancer on Adjuvant Aromatase Inhibitor Therapy

Breast Care ◽  
2020 ◽  
pp. 1-7
Author(s):  
Daniel María Lubián López ◽  
Carmen Aisha Butrón Hinojo ◽  
Manuel Sánchez-Prieto ◽  
Nicolás Mendoza ◽  
Rafael Sánchez-Borrego

<b><i>Introduction:</i></b> The aim of this study was to investigate whether postmenopausal women with breast cancer (BC) on adjuvant aromatase inhibitor (AI) therapy have a higher prevalence of female sexual dysfunction (FSD). Second, the aim was to determine the quality of life (QoL) and level of anxiety depending on whether or not they are AI users. <b><i>Methods:</i></b> A prospective cross-sectional study involving 168 patients was performed. Three questionnaires were carried out: sexual functioning was evaluated with the Female Sexual Function Index (FSFI), while the EORTC QLQ-BR23 measures to study QoL in patients with BC and the State-Trait Anxiety Inventory (STAI) questionnaire (trait and status) were used to assess anxiety status in patients under treatment with AIs or not. <b><i>Results:</i></b> 47.6% (80/168) of the postmenopausal BC survivors were not sexually active (mean time after surgery: 48.6 months) despite a relatively low mean age (56.43 years). Postmenopausal AI-treated women had significantly worse sexual function as measured by the FSFI (23.40 ± 5.26 vs. 30.16 ± 2.24; <i>p</i> = 0.000). There were significant differences between both groups in all domains, except orgasm. The QoL score was 37.67 ± 7.38 in AI users versus 39.00 ± 1.44 among nonusers (<i>p</i> = 0.053). Patients under endocrine treatment also presented STAI scores significantly higher (25.83 ± 4.99 vs. 19.00 ± 7.12; <i>p</i> = 0.000). Trait anxiety was high in both groups, but this was not statistically significant. <b><i>Conclusions:</i></b> We observed a high prevalence of sexual inactivity among BC survivors regardless of AI use. Patients with AI use presented significantly higher prevalence of FSD, worse QoL, and greater anxiety.

Author(s):  
Fateme Zahra Karimi ◽  
Leila Pourali ◽  
Elahe Hasanzadeh ◽  
Seyede Fateme Nosrati Hadiabad ◽  
Nasim Pouresmaeili ◽  
...  

Nowadays, women have a longer menopausal duration due to the worldwide dramatic life expectancy increase. Sexual dysfunction is one of the most prevalent problems during menopause that affect women`s quality of life, mental health, and interpersonal relationship. This study aimed to investigate sexual dysfunction and its contributing factors amongst married postmenopausal women. This cross-sectional study was conducted among 164 postmenopausal women who attended the menopause clinic of the academic hospitals in Mashhad during 2017-2018. Data were collected using a checklist that included demographic and reproductive information and the validated Persian version of the Female Sexual Function Index questionnaire (FSFI). The mean age of participants was 53.55±6.25 years. The mean FSFI score was 20.06±6.66, and 65.2% of women had sexual dysfunction. The most disturbed sexual domains were; desire (86%, n: 141), arousal (82.3%, n: 135), lubrication (71.3%, n: 117) and sexual satisfaction (70.1%, n: 115), respectively. The partner`s age (P=0.01), time since menopause onset (P=0.01), age at marriage (P=0.02), and frequency of sexual intercourse (P˂0.0001) had a significant relationship with sexual function. The sexual function of postmenopausal women in this study was highly deteriorated. The associated factors were; older age of the spouse, younger age at marriage, longer time since menopause onset, and lower frequency of sexual intercourse. It is important to determine perimenopausal women who are at potential risk of sexual dysfunction and consult them for preventive programs and strategies.  


Author(s):  
Socorro Rejany Sales Silva Trento ◽  
Alberto Madeiro ◽  
Andréa Cronemberger Rufino

Abstract Objective To assess the sexual function and associated factors in postmenopausal women. Methods This a descriptive, cross-sectional study with 380 women aged 40 to 65 years, users of public health services in 2019. Questionnaires were applied on demographic characteristics, on climacteric symptoms (menopause rating scale) and on sexual function (sexual quotient, female version). Bivariate and multiple analyses by logistic regression were performed, with adjusted odds ratios (ORad) and 95% confidence intervals (95%CIs). Results More than half (243/64%) of the participating women were at risk of sexual dysfunction, with lower scores in the domains of sexual desire and interest, comfort, orgasm, and satisfaction. Women with a partner (ORad 2.07; 95%CI 1.03–4.17) and those who reported sleep problems (ORad 2.72; 95%CI 1.77–4.19), depressed mood (ORad 2.03; 95%CI 1.32–3.10), sexual complaints (ORad 8.16; 95%CI 5.06–13.15), and vaginal dryness (ORad 3.44; 95%CI 2.22–5.32) showed greater chance of sexual dysfunction. Conclusion There was a high prevalence of sexual dysfunction, with the influence of conjugality and climacteric symptoms on sexual function.


Author(s):  
Gustavo Maximiliano Dutra da Silva ◽  
Sônia Maria Rolim Rosa Lima ◽  
Benedito Fabiano dos Reis ◽  
Carolina Furtado Macruz ◽  
Sóstenes Postigo

Abstract Objective The incidence of obesity, which is a chronic condition, has increased in recent years. The association between obesity and female sexual dysfunction remains unclear, particularly in postmenopausal women. In the present study, we evaluated whether obesity is a risk factor for sexual dysfunction in postmenopausal women. Methods This is a cross-sectional study that analyzed data from interviews of postmenopausal women at the Climacteric Outpatient Clinic from 2015 to 2018. After applying the inclusion and exclusion criteria, 221 women aged between 40 and 65 years old were selected and invited to participate in the study. Obesity was diagnosed according to body mass index (BMI). The participants were grouped into the following BMI categories: group 1, 18.5–24.9 kg/m2 (normal); group 2, 25.0–29.9 kg/m2 (overweight); and group 3, ≥30.0 kg/m2 (obese). Sexual function was assessed using the Female Sexual Function Index (FSFI) questionnaire. Cutoff points of ≥23 and ≥26.5 were adopted to define a diagnosis of female sexual dysfunction (FSD) based on the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revision by the American Psychiatric Association (DSM-IV-TR). Results The desire and arousal scores were statistically higher in the normal BMI group than in the obese group (p = 0.028 and p = 0.043, respectively). The satisfaction scores were statistically higher in the normal BMI group than in the overweight and obese groups (p < 0.05). The total FSFI score statistically differed among the BMI categories (p = 0.027). Conclusion In the present study, obese and overweight postmenopausal women had higher total scores than women with normal BMI. Our results show that obese and overweight postmenopausal women had a higher index of dysfunction in desire and arousal and lower sexual satisfaction than normal-weight women.


2020 ◽  
Vol 2 (1) ◽  
pp. 87-92
Author(s):  
Suvarna Jyothi Kantipudi ◽  
Navina Suresh ◽  
Poornima Ayyadurai ◽  
Sathianathan Ramanathan

Background: Sexual dysfunction is common in females with schizophrenia and is attributed to multiple causes, including individual psychopathology and antipsychotics. Understanding the impact of relationship satisfaction on sexual functioning is not widely studied in schizophrenia. Women caregivers also experience sexual problems and were not studied in the past. Aim: To assess the nature and occurrence of sexual dysfunction in women with schizophrenia in comparison to caregivers of males without severe mental disorder. Methods: A cross-sectional study was conducted. A total of 30 women with schizophrenia were recruited as cases and 26 age-matched controls were recruited from female caregivers. All subjects were assessed using standardized tools such as Female Sexual Function Index (FSFI) and Relationship Assessment Scale along with sociodemographic questionnaire. Results: There was a significant difference in FSFI scores and relationship scores between women with schizophrenia and caregiver control subjects. The relationship quality was better in patients with schizophrenia when compared to caregivers unlike sexual functioning. Conclusion: Sexual functioning in women is a complex phenomenon. A holistic biopsychosocial approach is necessary to understand women’s sexual function.


2018 ◽  
Vol 6 (4) ◽  
pp. 15
Author(s):  
Alireza Shafiee Kandjani ◽  
Mohammad Reza Hosseinpour ◽  
Hossein Daneshamooz ◽  
Habib Shoja ◽  
Leila Nikniaz

Background: Sexual dysfuntion is a common complication of diabetes and its psychiatric and physical affects may obligate a huge burden compromising patients’ matrimonial, inter-personal and marital relationships. Current study is aimed to evaluate the frequency of sexual dysfunctions in type 2 diabetic women during 2015-2016 in Tabriz, Iran. Materials and Methods: Current cross-sectional study evaluated data gathered from 18-45 years of age type 2 diabetic women attending diabetes care centres of Tabriz. Sample size was estimated to be 300 and the sampling process fulfilled using cluster sampling methods according to the inclusion criteria. Female Sexual Function Index (FSFI) is used as the research tool. Descriptive data analysis were applied to achieve results using SPSS 20. Results: Non-parametric binominal tests reflects statistically significant decrease in sexual activity of the diabetic patients (p= 0.001). The probability of the catogry below the cut point was 1 which means that 100% of type 2 diabetic women suffer from sexual dysfunction. All items of sexual function are found to be below the average normal measurments. Conclusion: Type 2 diabetic women are vastly under the burden of sexual dysfunction, which affects their physical and psychological health. Current study showed the need to provide sufficient and available care services and organized education courses for diabetic women.


2020 ◽  
Vol 73 (suppl 4) ◽  
Author(s):  
Paula Renata Amorim Lessa Soares ◽  
Cinthia Gondim Pereira Calou ◽  
Samila Gomes Ribeiro ◽  
Priscila de Souza Aquino ◽  
Paulo Cesar de Almeida ◽  
...  

ABSTRACT Objectives: to assess the sexual function of pregnant women and the influence of sociodemographic, obstetric, and behavioral factors on sexual dysfunction. Methods: cross-sectional study conducted with 141 pregnant women attended by the Single Health System and 120 by one private service, totaling 261 participants. A questionnaire containing sociodemographic, obstetric, and behavioral variables was applied, as well as the Female Sexual Function Index instrument, which was used to assess sexual function. Associations between variables and sexual dysfunction were made using the chi-square test, considering a statistically significant result when p < 0.05. Results: among the participants, 32.1% had sexual dysfunction, and the variables “age”, “income” and “type of health service” had an influence on sexual dysfunction. The prevalence of pregnant women was between 21 and 30 years old (p < 0.001), with an income between 1 and 2 minimum wages (p = 0.048) and used the public health system network (p = 0.000). Conclusions: the factors associated with sexual dysfunction are “young pregnant women”, “low income” and “attended in the public health service”.


2020 ◽  
Vol 16 ◽  
Author(s):  
Azam Mohammadi ◽  
Fatemeh Effati-Daryani ◽  
Somayeh Zarei ◽  
Sakineh Ghasemi Yngyknd ◽  
Elnaz Hemmati ◽  
...  

Background: With the global prevalence of COVID-19, general fear has increased along with misinformation and rumors that could affect a pregnant woman's psyche, and her sexual function. Objective: This study was conducted to determine the prevalence of sexual dysfunction and related factors in pregnant women during the COVID-19 pandemic. Methods: This cross-sectional study was performed on 205 pregnant women. Data collection tools included a sociodemographic characteristics questionnaire and the FSFI, both of which were completed online. Results: The mean (SD) of the overall score of sexual function was 21.54 (8.37), and 80% of participants suffered from sexual dysfunction. The results of the adjusted general linear model showed that the variables of spouse's age and occupation, place of residence, and marital satisfaction were significantly statistically correlated with sexual function score. In women whose husbands were under 30 years of age compared with those over 35 years of age, in women living in their parents' homes compared to those living in private homes, and in women with high or extremely high marital satisfaction compared to moderate satisfaction, the sexual function score was higher. Conversely, women whose husbands were blue-collar workers had lower sexual function scores than those whose husbands were white-collar workers. Conclusion: It is necessary to consider socio-demographic factors in the treatment and prevention of this sexual function disorders. It is recommended that the appropriate solutions be provided and implemented by the relevant authorities, taking into account the effective modifying factors, in order to further improve this dimension of married life.


2016 ◽  
Vol 28 (6) ◽  
pp. 931-936 ◽  
Author(s):  
Maíra de Menezes Franco ◽  
Patricia Driusso ◽  
Kari Bø ◽  
Daniela Cristina Carvalho de Abreu ◽  
Lucia Alves da Silva Lara ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Soheila Nazarpour ◽  
Masoumeh Simbar ◽  
Mobina Khorrami ◽  
Zahra Jafari Torkamani ◽  
Reyhaneh Saghafi ◽  
...  

Abstract Background Postmenopause physiological changes may alter body image (BI) during the postmenopausal period of life. Body image dissatisfaction may have negative effects on the sexual function of women. The present study aims to assess the relationship between body image and sexual function during the postmenopausal period. Methods This cross-sectional study was performed on 231 postmenopausal women who were menopausal during the recent 5 years, aged > 40 years old, and referring to health centers in Tehran-Iran. The participants were recruited using a multi-stage sampling method. Data were collected using 3 questionnaires including socio-demographic, Fisher’s Body Image, and female sexual function index (FSFI). Data were analyzed using SPSS 24 and multiple regression, Mann–Whitey, Pearson, and Spearman correlation tests. Results Two hundred thirty-one postmenopausal women aged 52.53 ± 5.32 (mean ± SD) years old participated in the study. The mean and standard deviation of FSFI and BI of the women were respectively 19.59 ± 11.11(ranges 1.2–36) and 155.43 ± 37.09 (ranges from 46 to 230). According to FSFI, 62.8% of female sexual dysfunction (FSD) was reported. There were significant correlations between scores of total and all domains of FSFI with scores of total and all dimensions of BI. There was also a positive correlation between education and family income of the women and a negative correlation between age of husband and duration of menopause with their sexual function. Significant relationships were also shown between the women's and the husbands' jobs with the total score of women's sexual function. According to the multiple linear regression model, BI was a significant predictor of sexual function in postmenopausal women. Conclusion Body image is effective on the sexual function of postmenopausal women. Therefore, body image is necessary to be considered in future postmenopausal health promotion programs.


Background and Aim: The Breast cancer is very common. These patients develop sexual dysfunction following chemotherapy. The aim of this study was to evaluate the effect of chemotherapy in breast cancer patients on their sexual function. Materials and Methods: This descriptive-analytical cross-sectional study was performed on patients with breast cancer referred to Iran-Mehr Medical Center in winter 2018 undergoing chemotherapy. 119 patients were enrolled in the study under census. The Rosen’s Sexual Function Questionnaire was used to collect data. Data were analyzed by using SPSS (Version 16) and Smirnov-Kolmogorov, Kruskal-Wallis and Mann-Whitney tests at the significant level of (P<0.05). Results: In terms of sexual function, the lowest score was 2.40 and the highest score was 14.90. In the study of sexual function components, patients were in the worst condition in terms of pain, 0.84±0.75 and humidity 0.85±0.73. The mean scores of other components included orgasm 1.13±0.64, irritability 1.05±0.84, satisfaction 1.23±0.30 and sexual desire 1.66±0.66, respectively. The only factor affecting sexual function Location, age of marriage and age of patients. Conclusion: The score of sexual function was less than the minimum; the most disorders were recorded for the components of pain and humidity. Factors affecting sexual function were included: location, years of menopause, type of treatment, age of patients and years of marriage. It is recommended that the sexual status of breast cancer patients be evaluated before and during treatment and that the necessary training be provided to inform patients about this disorder and the necessary treatments to improve sexual function.


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