Superficial Acral Fibromyxoma: Clinicopathologic Analysis of Five Cases

2021 ◽  
pp. 1-7
Author(s):  
Soumiya Chiheb ◽  
Maha Mouradi ◽  
Fouzia Hali
Keyword(s):  
Soft Tissue ◽  
Young Woman ◽  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Clinicopathologic Features ◽  
Male Predominance ◽  
Fibrous Tumor ◽  
Middle Aged Adults ◽  
Slow Growing ◽  
Superficial Acral Fibromyxoma

Superficial acral fibromyxoma is a relatively rare benign slow-growing soft-tissue tumor, first described by Fetsch’s group [<i>Hum Pathol</i>. 2001;32:704–14]. Since then, around three hundred publications have concerned this relatively new entity. The tumor involves peri- and subungual regions of fingers and toes in middle-aged adults with slight male predominance. This acral fibrous tumor is poorly known, and in certain cases, histology results may suggest myxoid dermatofibrosarcoma, which carries a completely different prognosis. In this article, we discuss the clinicopathologic features of this acral fibrous tumor through the report of 5 cases including 1 particular clinical presentation that revealed as a retronychia in a young woman.

Superficial Acral Fibromyxoma: An Overview

2011 ◽  
Vol 135 (8) ◽  
pp. 1064-1066 ◽  
Author(s):  
Harty Ashby-Richardson ◽  
Gary S Rogers ◽  
Miguel J Stadecker
Keyword(s):  
Soft Tissue ◽  
Stromal Cells ◽  
Soft Tissue Tumor ◽  
Cellular Proliferation ◽  
Epithelial Membrane Antigen ◽  
Complete Excision ◽  
Mitotic Figures ◽  
Slow Growing ◽  
Superficial Acral Fibromyxoma

Superficial acral fibromyxoma is a rare, slow-growing soft tissue tumor, which is commonly located in the periungual and subungual regions of the fingers and toes in adults. To date, fewer than 50 cases have been reported worldwide. Microscopic examination reveals a moderately circumscribed, nonencapsulated tumor situated in the dermis, which may also extend into the subcutis. The neoplasm consists of a moderately cellular proliferation of stellate and spindle-shaped fibroblast-like cells embedded in a myxocollagenous stroma. Mast cells are easily identified throughout this lesion. Multinucleated stromal cells may also be present, but nuclear atypia and mitotic figures are rare. The tumor shows immunoreactivity for CD34, epithelial membrane antigen, CD99, and less frequently, CD10. Superficial acral fibromyxoma has a benign behavior but may persist or recur if inadequately excised. Therefore, complete excision and close follow-up are advised.

Superficial Acral Fibromyxoma

2021 ◽  
Vol 111 (5) ◽  
Author(s):  
Seher Bostanci ◽  
Bengü Nisa Akay ◽  
Zehra Akkaya ◽  
Merve Aygun ◽  
Kerem Başarır ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Clinical Diagnosis ◽  
Soft Tissue Tumor ◽  
Great Toe ◽  
Tissue Tumor ◽  
Radiologic Findings ◽  
Slow Growing ◽  
Superficial Acral Fibromyxoma

Superficial acral fibromyxoma is a rare, benign, slow-growing, soft-tissue tumor commonly located in the acral regions, with a predilection for the great toe, developing from the nail unit. Because of its nonspecific features and rarity, clinical diagnosis is difficult. In this article, we present a case of superficial acral fibromyxoma located in the nail unit with new dermatoscopic and radiologic findings that have not been previously reported in the literature.

scholarly journals Dendritic Myxofibrolipoma: Often Misdiagnosed as Sarcoma

2011 ◽  
Vol 4 (3) ◽  
pp. 171-174 ◽  
Author(s):  
Awatif Y. Al-Maskery ◽  
Salem M. Al-Sidairy ◽  
Aisha S. Al-Hamadani
Keyword(s):  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Complete Excision ◽  
Lower Lip ◽  
Benign Soft Tissue Tumor ◽  
Proper Diagnosis ◽  
Fibrous Tumor ◽  
Combined Feature

The author describes a benign soft tissue tumor that could be easily mistaken for sarcoma. It represents a combined feature of solitary fibrous tumor and spindle cell lipoma. The clinical presentation, diagnosis, and management of this lesion are discussed. It highlights the importance of proper diagnosis to prevent unnecessary and ineffective treatment by clinicians as the complete excision of this lesion is the treatment of choice and recurrence is very unlikely. It is believed that this case is the first reported case of dendritic myxofibrolipoma occurring in the lower lip mucosa in an Omani patient.

scholarly journals Subungual Glomus Tumor- Clinical Presentation And Treatment

2014 ◽  
Vol 3 (2) ◽  
pp. 45-48 ◽  
Author(s):  
Shyamal Chandra Debnath ◽  
Suman Kumar Roy ◽  
RR Kairy
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Glomus Tumor ◽  
Rare Condition ◽  
Surgical Excision ◽  
Tissue Mass ◽  
Delay In Diagnosis ◽  
Nail Deformity

Glomus tumor is a rare condition and constitutes only 1 % of all soft tissue tumor of body. Glomus tumor is familiar for its unusual presentation and long standing symptoms due to delay in diagnosis. Authors have presented the clinical behavior and treatment of 7 patients with subungual soft tissue mass. Following surgical excision, all patients cured of symptoms, at the end of follow up, no recurrence occurred; post operative nail deformity was insignificant. DOI: http://dx.doi.org/10.3329/bdjps.v3i2.18250 Bangladesh Journal of Plastic Surgery July 2012, 3(2): 45-48

scholarly journals Embryonal Rhabdomyosarcoma with Posttherapy Cytodifferentiation and Aggressive Clinical Course

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Maniraj Jeyaraju ◽  
Regina Ann Macatangay ◽  
Ashley Taylor-King Munchel ◽  
Teresa Anne York ◽  
Elizabeth A. Montgomery ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Clinical Course ◽  
Good Prognosis ◽  
Embryonal Rhabdomyosarcoma ◽  
Clinicopathologic Features ◽  
Malignant Soft Tissue Tumor ◽  
Clinicopathologic Factors ◽  
Aggressive Clinical Course ◽  
Malignant Soft Tissue

Rhabdomyosarcoma is the most common soft tissue sarcoma in children and adolescents. Embryonal rhabdomyosarcoma (ERMS), its most common subtype, is a malignant soft tissue tumor with morphologic and immunophenotypic features of embryonic skeletal muscle. The histologic findings in ERMS typically include a range of differentiation in rhabdomyoblasts from primitive to terminally differentiated forms, and the latter become more prominent after chemotherapy-induced cytodifferentiation. Several reports have shown therapy-related cytodifferentiation to portend a good prognosis in ERMS. We discuss the case of a pediatric patient who presented with ERMS of the orbit. Although her tumor showed extensive posttreatment cytodifferentiation and several other good prognostic clinicopathologic factors, it pursued an aggressive course, resulting in early metastasis and death. This case represents an unusual course and may be instructive as to the clinicopathologic features impacting prognostication, and ultimately the biology, of this aggressive family of tumors.

scholarly journals Superficial Acral Fibromyxoma. Un Uncommon Tumor of the Foot

2019 ◽  
Vol 13 (4) ◽  
pp. 251-4
Author(s):  
Santiago Pache ◽  
Rodrigo Fratelli ◽  
Javier Cedrani ◽  
Paola Filomeno ◽  
Thomas Clanton
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Female Patient ◽  
Soft Tissue Tumor ◽  
Wide Resection ◽  
Level Of Evidence ◽  
Fifth Toe ◽  
Hands And Feet ◽  
Superficial Acral Fibromyxoma ◽  
Uncommon Tumor

This study presents a case report of a 52-year-old female patient with a superficial acral fibromyxoma (SAF) of her left foot fifth toe. This is a very uncommon soft tissue tumor that affects mainly hands and feet, with a special predilection for toes, with the hallux most frequent. The tumor in this case was 3cm long and 2.5cm wide, which was unusually large. Few cases are larger than 2cm long and localized on the fifth toe. Thetreatment was wide resection of the tumor through amputation of the fifth toe. Level of Evidence V; Therapeutic Studies; Expert Opinion.

scholarly journals Painful Elastofibroma Dorsi: A Report of a Case and a Brief Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Evangelos Falidas ◽  
Dimitrios Arvanitis ◽  
Georgios Anyfantakis ◽  
Angelos Pazidis ◽  
Zacharoula Koukouli ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Elderly People ◽  
Clinical Features ◽  
Soft Tissue Tumor ◽  
Review Of The Literature ◽  
Tissue Tumor ◽  
Elastofibroma Dorsi ◽  
Pathologic Findings ◽  
Benign Soft Tissue Tumor ◽  
Slow Growing

Elastofibroma dorsi (ED) is an uncommon, slow-growing, benign, soft tissue tumor of unclear pathogenesis, typically located at the subscapular region of elderly people. It may be unilateral or bilateral. Though many patients are asymptomatic, ED can cause local deformity and symptoms such as periscapular pain or discomfort. Herein we report a case of a 65-year-old woman with painful ED. Clinical features, radiodiagnostic, intraoperative, and pathologic findings, and a brief review of the literature are performed.

Pedal Presentation of Superficial Acral Fibromyxoma

2017 ◽  
Vol 107 (1) ◽  
pp. 72-75
Author(s):  
Robin Lenz ◽  
Rene Kafka ◽  
Kevin Jules ◽  
Bradley W. Bakotic
Keyword(s):  
Soft Tissue ◽  
Unusual Case ◽  
Medical Literature ◽  
Soft Tissue Neoplasm ◽  
Slow Growing ◽  
Superficial Acral Fibromyxoma

Superficial acral fibromyxoma is a benign and slow-growing solitary soft-tissue neoplasm. Since being described in 2001, more than 100 cases of superficial acral fibromyxoma on the foot have been reported worldwide, none of which have been reported in the podiatric medical literature. Only nine cases of superficial acral fibromyxoma have been reported with presentation on the plantar heel. We report an unusual case of a 47-year-old Jamaican woman with a painful, erythematous nodule on her right heel that was diagnosed as superficial acral fibromyxoma.

scholarly journals Myxoinflammatory Fibroblastic Sarcoma: Review and Update

2017 ◽  
Vol 141 (11) ◽  
pp. 1503-1507 ◽  
Author(s):  
David R. Lucas
Keyword(s):  
Soft Tissue ◽  
Local Recurrence ◽  
Soft Tissue Tumor ◽  
High Rate ◽  
High Grade ◽  
Clinicopathologic Features ◽  
Molecular Features ◽  
Microscopic Features ◽  
Myxoinflammatory Fibroblastic Sarcoma ◽  
Low Rate

Myxoinflammatory fibroblastic sarcoma is a rare soft tissue tumor with most occurring in the distal extremities of adult patients. It has a high rate of local recurrence and a low rate of metastasis. Because it may appear benign on clinical examination, and because the microscopic features are generally underrecognized, it is often inadequately treated and misdiagnosed. In this review, based upon experience and that of the literature, the intent is to highlight salient clinicopathologic features, detail the broad microscopic spectrum including high-grade aggressive variants, review the molecular features, and discuss its relation to hemosiderotic fibrolipomatous tumor.

scholarly journals Dermatofibrosarcoma Protuberans: Insights into a Rare Soft Tissue Tumor

2016 ◽  
Vol 6 ◽  
pp. 16 ◽  
Author(s):  
Aliya Sarhan Al Barwani ◽  
Sawsan Taif ◽  
Reem Ahmed Al Mazrouai ◽  
Khamis Salim Al Muzahmi ◽  
Asif Alrawi
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Treatment Options ◽  
Dermatofibrosarcoma Protuberans ◽  
High Rate ◽  
Imaging Findings ◽  
Full Extent ◽  
Radiological Appearance ◽  
Characteristic Features

Dermatofibrosarcoma protuberans (DFSP) is a rare soft tumor which originally represents a cutaneous sarcoma. It grows slowly and presents usually as nodular superficial lesion on the trunk or the extremities. Although these tumors are locally aggressive with high rate of recurrence following surgery; the prognosis is considered excellent when it is effectively treated. The radiological appearance of this tumor has rarely been studied and findings infrequently discussed in the literature probably because many lesions underwent resection before imaging. Although imaging is infrequently performed for this lesion; it can show characteristic features and demonstrate the full extent. Imaging may also play a role in the differentiation of this tumor from more serious soft tissue lesions such as more aggressive sarcomas and hemangioma. In this article, we discuss the imaging findings of DFSP that can aid in its diagnosis and its variable appearances. In addition; the clinical presentation and treatment options are also described with review of the previous literature.

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