SEM Evaluation of the Effects of Laser-Mediated Implant Surface Decontamination: An In Situ Human Pilot Study

2021 ◽  
Vol 41 (5) ◽  
pp. 711-717
Author(s):  
Eric Linden ◽  
Charles Cobb ◽  
Paul Fletcher ◽  
Donggao Zhao
Keyword(s):  
Pilot Study ◽  
Implant Surface ◽  
Surface Decontamination

Regenerative treatment of peri-implantitis following implant surface decontamination with titanium brush and antimicrobial photodynamic therapy: a case series with reentry

2020 ◽  
Author(s):  
Pier Poli ◽  
Francisley Avila Souza ◽  
Mattia Manfredini ◽  
Carlo Maiorana ◽  
Mario Beretta
Keyword(s):  
Photodynamic Therapy ◽  
Clinical Case ◽  
Case Series ◽  
Antimicrobial Photodynamic Therapy ◽  
Implant Surface ◽  
Surface Decontamination

Not required for Clinical case letters according to the authors' guidelines.

Feasibility study of technology-enabled prevention intervention for children and families (Preprint)

2019 ◽  
Author(s):  
Nikki Theofanopoulou ◽  
Katherine Isbister ◽  
Julian Edbrooke-Childs ◽  
Petr Slovák
Keyword(s):  
Emotion Regulation ◽  
Pilot Study ◽  
Low Cost ◽  
Digital Camera ◽  
Well Being ◽  
Structured Interview ◽  
Object A ◽  
Intervention Delivery ◽  
Parents And Children

BACKGROUND A common challenge within psychiatry and prevention science more broadly is the lack of effective, engaging, and scale-able mechanisms to deliver psycho-social interventions for children, especially beyond in-person therapeutic or school-based contexts. Although digital technology has the potential to address these issues, existing research on technology-enabled interventions for families remains limited. OBJECTIVE The aim of this pilot study was to examine the feasibility of in-situ deployments of a low-cost, bespoke prototype, which has been designed to support children’s in-the-moment emotion regulation efforts. This prototype instantiates a novel intervention model that aims to address the existing limitations by delivering the intervention through an interactive object (a ‘smart toy’) sent home with the child, without any prior training necessary for either the child or their carer. This pilot study examined (i) engagement and acceptability of the device in the homes during 1 week deployments; and (ii) qualitative indicators of emotion regulation effects, as reported by parents and children. METHODS In this qualitative study, ten families (altogether 11 children aged 6-10 years) were recruited from three under-privileged communities in the UK. The RA visited participants in their homes to give children the ‘smart toy’ and conduct a semi-structured interview with at least one parent from each family. Children were given the prototype, a discovery book, and a simple digital camera to keep at home for 7-8 days, after which we interviewed each child and their parent about their experience. Thematic analysis guided the identification and organisation of common themes and patterns across the dataset. In addition, the prototypes automatically logged every interaction with the toy throughout the week-long deployments. RESULTS Across all 10 families, parents and children reported that the ‘smart toy’ was incorporated into children’s emotion regulation practices and engaged with naturally in moments children wanted to relax or calm down. Data suggests that children interacted with the toy throughout the duration of the deployment, found the experience enjoyable, and all requested to keep the toy longer. Child emotional connection to the toy—caring for its ‘well-being’—appears to have driven this strong engagement. Parents reported satisfaction with and acceptability of the toy. CONCLUSIONS This is the first known study investigation of the use of object-enabled intervention delivery to support emotion regulation in-situ. The strong engagement and qualitative indications of effects are promising – children were able to use the prototype without any training and incorporated it into their emotion regulation practices during daily challenges. Future work is needed to extend this indicative data with efficacy studies examining the psychological efficacy of the proposed intervention. More broadly, our findings suggest the potential of a technology-enabled shift in how prevention interventions are designed and delivered: empowering children and parents through ‘child-led, situated interventions’, where participants learn through actionable support directly within family life, as opposed to didactic in-person workshops and a subsequent skills application.

scholarly journals Shale Oil Recovery by In-Situ Retorting-A Pilot Study

1970 ◽  
Vol 22 (12) ◽  
pp. 1520-1524 ◽  
Author(s):  
E.L. Burwell ◽  
T.E. Sterner ◽  
H.C. Carpenter
Keyword(s):  
Pilot Study ◽  
Oil Recovery ◽  
Shale Oil

Effect of Ultraviolet Irradiation of the Implant Surface on Progression of Periimplantitis—A Pilot Study in Dogs

2016 ◽  
Vol 25 (1) ◽  
pp. 47-53 ◽  
Author(s):  
Kouken Ishii ◽  
Masato Matsuo ◽  
Noriyuki Hoshi ◽  
Shun-suke Takahashi ◽  
Ryota Kawamata ◽  
...  
Keyword(s):  
Pilot Study ◽  
Ultraviolet Irradiation ◽  
Implant Surface

scholarly journals Cold atmospheric plasma coupled with air abrasion in liquid medium for the treatment of peri-implantitis model grown with a complex human biofilm: an in vitro study

2021 ◽  
Author(s):  
Wang Lai Hui ◽  
Vittoria Perrotti ◽  
Adriano Piattelli ◽  
Kostya (Ken) Ostrikov ◽  
Zhi Fang ◽  
...  
Keyword(s):  
Liquid Medium ◽  
Statistical Significance ◽  
Atmospheric Plasma ◽  
Air Abrasion ◽  
Implant Surface ◽  
Cold Atmospheric Plasma ◽  
Surface Features ◽  
Treatment Groups ◽  
Surface Decontamination

Abstract Objective Treatment of implants with peri-implantitis is often unsuccessful due to residual microbial biofilm hindering re-osseointegration. The aim of this study was to treat biofilm-grown titanium (Ti) implants with different modalities involving air abrasion (AA) and cold atmospheric plasma (CAP) to compare the effectiveness in surface decontamination and the alteration/preservation of surface topography. Materials and methods Saliva collected from a peri-implantitis patient was used to in vitro develop human biofilm over 35 implants with moderately rough surface. The implants were then mounted onto standardized acrylic blocks simulating peri-implantitis defects and treated with AA (erythritol powder), CAP in a liquid medium, or a combination (COM) of both modalities. The remaining biofilm was measured by crystal violet (CV). Surface features and roughness before and after treatment were assessed by scanning electron microscope (SEM). The data were statistically analyzed using Kruskal-Wallis followed by Tukey’s multiple comparison test. Results In the present peri-implantitis model, the human complex biofilm growth was successful as indicated by the statistical significance between the negative and positive controls. All the treatment groups resulted in a remarkable implant surface decontamination, with values very close to the negative control for AA and COM. Indeed, statistically significant differences in the comparison between the positive control vs. all the treatment groups were found. SEM analysis showed no post-treatment alterations on the implant surface in all the groups. Conclusions Decontamination with AA delivering erythritol with or without CAP in liquid medium demonstrated compelling efficacy in the removal of biofilm from implants. All the tested treatments did not cause qualitative alterations to the Ti surface features. No specific effects of the CAP were observed, although further studies are necessary to assess its potential as monotherapy with different settings or in combination with other decontamination procedures. Clinical relevance CAP is a promising option in the treatment of peri-implantitis because it has potential to improve the elimination of bacterial plaque from implant surfaces, in inaccessible pockets or during open-flap debridement, and should stimulate the process of the re-osseointegration of affected dental implants by not altering surface features and roughness.

scholarly journals Pilot Study on In-Situ Purification Tank for River Outfall

2017 ◽  
Vol 05 (04) ◽  
pp. 57-64
Author(s):  
志金 黄
Keyword(s):  
Pilot Study

scholarly journals Immediate Implant Placement in Infected Sockets: A Consecutive Cohort Study

2020 ◽  
Vol 11 (2) ◽  
pp. 167-173 ◽  
Author(s):  
Ashish Kakar ◽  
Kanupriya Kakar ◽  
Minas D. Leventis ◽  
Gaurav Jain
Keyword(s):  
Bone Graft ◽  
Clinical Results ◽  
Bone Graft Substitute ◽  
Graft Material ◽  
Success Rates ◽  
Implant Surface ◽  
Implant Placement ◽  
Immediate Placement ◽  
Immediate Implant

Introduction: Immediate placement of implants in a fresh post-extraction socket is an increasingly popular and established treatment option. However, active infection in the extraction site may adversely affect the outcome of this procedure. This study was designed to assess the clinical results of immediate placement of dental implants in infected extraction sockets using a standardized protocol, which included (a) the use of an Er,Cr:YSGG laser for the decontamination of the infected socket prior to implant insertion, and (b) the utilization of an in situ hardening alloplastic bone graft substitute to augment the gap between the implant surface and the labial plate of bone. Patients and Methods: A retrospective record review was used to identify 68 patients who had implants placed as per the described protocol. A total of 126 implants were placed in 68 patients (65 implants in the maxilla, 61 implants in the mandible). The implants were loaded 136 ± 73 days (mean ± standard deviation; range: 37–400 days) after implant placement. Eight patients (16 implants) were subsequently lost to follow up. Results: 105 of the 110 implants (95.45%) placed immediately in the infected sites using the described protocol survived after prosthetic loading. Conclusion: Immediate implant placement in previously infected sites using the protocols mentioned in our study with laser decontamination of the socket, grafting with an in situ hardening alloplastic bone graft material and non-submerged healing shows a similar survival rate to the published success rates for immediate implants placed in non-infected sites.

Nanotechnology Enabled In Situ Orthopaedic Sensors for Personalized Medicine

2012 ◽  
Vol 86 ◽  
pp. 40-50
Author(s):  
Sirinrath Sirivisoot ◽  
Thomas J. Webster
Keyword(s):  
Bone Growth ◽  
Electrochemical Sensors ◽  
Electrochemical Analysis ◽  
Matrix Proteins ◽  
Implant Design ◽  
Implant Surface ◽  
Cellular Events ◽  
Bone Deposition ◽  
Made In

Although improvements have been made in implant design to increase bone formation and promote successful osseointegration using nanotechnology, the clinical diagnosis of early bone growth surrounding implants remains problematic. The development of a device allowing doctors to monitor the healing cascade and to diagnose potential infection or inflammation is necessary. Biological detection can be examined by the electrochemical analysis of electron transfer (or redox) reactions of extracellular matrix proteins involved in bone deposition and resorption. The use of nanomaterials as signal amplifiers in electrochemical sensors has greatly improved the sensitivity of detection. Nanotechnology-enabled electrochemical sensors that can be placed on the implant surface itself show promise as self-diagnosing devices in situ, possibly to detect new bone growth surrounding the implant and other cellular events to ensure implant success.

Is it possible to determine formation processes of organic deposits through polysaccharides? Pilot study from the prehistoric site in Brandýs nad Labem, Czech Republic

The Holocene ◽  
2017 ◽  
Vol 27 (9) ◽  
pp. 1273-1280
Author(s):  
Klement Rejšek ◽  
Jan Turek ◽  
Valerie Vranová ◽  
Roman Hadacz ◽  
Lenka Lisá
Keyword(s):  
Czech Republic ◽  
Pilot Study ◽  
Organic Material ◽  
Archaeological Site ◽  
Soil Samples ◽  
Formation Processes ◽  
Cultural Layer ◽  
Different Types ◽  
Organic Deposits

This paper deals with a possible interpretation value of biochemical methods in comparison with the classic tools of geoarchaeology for the evaluation of formation processes. Organic rich layers from the archaeological site Brandýs nad Labem-Vrábí were tested with the aim to determine the origin of several different types of soil organic material by analyzing the content of different sugars. The studied soil body showed signs of cultural layer, redeposited soils, and in situ developed soil. The analysis of different sugars was highlighted: soil samples taken from these layers were analyzed to assess the ratios of mannose + galactose to arabinose + xylose, and of rhamnose + fucose to arabinose + xylose, content of Corg and different nitrates, as well as different rates of absorbance. The results show that the interpretation values of polysaccharides evaluation didn’t bring significant results itself, but in combination with classical tools of geoarchaeology may bring interpretable and new results.

In Situ Bioremediation Pilot Study at a Former Manufactured Gas Plant Site

2009 ◽  
pp. 91-91-23
Author(s):  
DA English ◽  
JR Nelson ◽  
DA Hargens
Keyword(s):  
Pilot Study ◽  
In Situ Bioremediation ◽  
Manufactured Gas Plant ◽  
Plant Site
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