Abstract P095: Prospective Association of Physical Activity and Heart Failure Hospitalizations Among African-American Adults with Normal Ejection Fraction: The Jackson Heart Study

Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Patrick Koo ◽  
Annie Gjelsvik ◽  
Gaurav Choudhary ◽  
Wen-Chih Wu ◽  
Wei Wang ◽  
...  
Keyword(s):  
Physical Activity ◽  
Heart Failure ◽  
African American ◽  
Ejection Fraction ◽  
Activity Level ◽  
Normal Ejection Fraction ◽  
Jackson Heart Study ◽  
African American Adults ◽  
Heart Study ◽  
Crude Analysis

Introduction: Diastolic dysfunction (DD) with normal ejection fraction is prevalent in the African-American population due to a higher prevalence of associated risk factors. The potential benefit of moderate to vigorous physical activity (MVPA) to prevent heart failure admissions in African-American adults with normal ejection fraction is under-researched. The purpose of this study is to investigate the associations of DD and MVPA with heart failure hospitalizations (HFH). Hypothesis: We hypothesized that MVPA reduces the risk of HFH among African-American adults with normal ejection fraction. Methods: We performed a prospective analysis of 2,427 African-American adults who participated in the Jackson Heart Study and who had 2D echo and physical activity data and normal ejection fraction. MVPA per week is defined as the following: poor health [[Unable to Display Character: –]] 0 minutes; intermediate health [[Unable to Display Character: –]] 1-149 minutes; and ideal health [[Unable to Display Character: –]] ≥ 150 minutes. DD is defined as using ratio of the early to late ventricular filling velocities, ratio of pulmonary venous systolic to diastolic velocities, and pulmonary venous atrial reversal velocity. We employed multiple variable logistic and cox proportional regression analyses adjusted for age, gender, BMI, smoking, hypertension, DM, COPD, CKD, and CHD to determine the associations of DD and MVPA with HFH. Results: Of the eligible population, 1,209 (50%) have DD. There were 171 HFH. DD is associated with HFH in the crude analysis (OR=2.24, 95% CI 1.40-3.57). The association was markedly attenuated after adjusting for age (OR=1.03, CI 0.63-1.71). Intermediate and ideal health MVPA in the crude analysis were associated with lower risk of HFH (HR=0.50, 95% CI 0.35-0.71 and HR=0.18, 95% CI 0.09-0.36, respectively), and full models revealed HR=0.71, 95% CI 0.49-1.04 and HR=0.31, 95% CI 0.16-0.63, respectively. There was no interaction between physical activity level and DD on HFH. Conclusion: In conclusion, ideal health MVPA is associated with reduced risk of HFH, whereas, intermediate health MVPA revealed a trend in risk reduction in African-American with normal ejection fraction.

scholarly journals Pedometer determined physical activity tracks in African American adults: The Jackson Heart Study

2012 ◽  
Vol 9 (1) ◽  
Author(s):  
Robert L Newton ◽  
Hongmei Han M ◽  
Patricia M Dubbert ◽  
William D Johnson ◽  
DeMarc A Hickson ◽  
...  
Keyword(s):  
Physical Activity ◽  
African American ◽  
Jackson Heart Study ◽  
African American Adults ◽  
Heart Study

scholarly journals Validity and Calibration of Food Frequency Questionnaires Used with African-American Adults in the Jackson Heart Study

2009 ◽  
Vol 109 (7) ◽  
pp. 1184-1193.e2 ◽  
Author(s):  
Teresa C. Carithers ◽  
Sameera A. Talegawkar ◽  
Marjuyua L. Rowser ◽  
Olivia R. Henry ◽  
Patricia M. Dubbert ◽  
...  
Keyword(s):  
African American ◽  
Jackson Heart Study ◽  
Food Frequency ◽  
African American Adults ◽  
Heart Study

scholarly journals The Associations of Multiple Dimensions of Discrimination and Abdominal Fat in African American Adults: The Jackson Heart Study

2012 ◽  
Vol 43 (1) ◽  
pp. 4-14 ◽  
Author(s):  
DeMarc A. Hickson ◽  
Tené T. Lewis ◽  
Jiankang Liu ◽  
David L. Mount ◽  
Sinead N. Younge ◽  
...  
Keyword(s):  
African American ◽  
Abdominal Fat ◽  
Jackson Heart Study ◽  
African American Adults ◽  
Multiple Dimensions ◽  
Heart Study

scholarly journals Regional Adiposity and Risk of Heart Failure and Mortality: The Jackson Heart Study

2021 ◽  
Author(s):  
Vishal N. Rao ◽  
Christopher G. Bush ◽  
Morgana Mongraw‐Chaffin ◽  
Michael E. Hall ◽  
Donald Clark ◽  
...  
Keyword(s):  
Heart Failure ◽  
Computed Tomography ◽  
Adipose Tissue ◽  
Ejection Fraction ◽  
Preserved Ejection Fraction ◽  
Jackson Heart Study ◽  
Heart Study ◽  
Pericardial Adipose Tissue ◽  
All Cause Mortality ◽  
Regional Adiposity

Background Visceral adipose tissue (VAT) is associated with incident heart failure (HF) and HF with preserved ejection fraction, yet it is unknown how pericardial and abdominal adiposity affect HF and mortality risks in Black individuals. We examined the associations of pericardial adipose tissue (PAT), VAT, and subcutaneous adipose tissue (SAT) with incident HF hospitalization and all‐cause mortality in a large community cohort of Black participants. Methods and Results Among the 2882 Jackson Heart Study Exam 2 participants without prevalent HF who underwent body computed tomography, we used Cox proportional hazards models to examine associations between computed tomography–derived regional adiposity and incident HF hospitalization and all‐cause mortality. Fully adjusted models included demographics and cardiovascular disease risk factors. Median follow‐up was 10.6 years among participants with available VAT (n=2844), SAT (n=2843), and PAT (n=1386). Fully adjusted hazard ratios (95% CIs) of distinct computed tomography–derived adiposity measures (PAT per 10 cm 3 , VAT or SAT per 100 cm 3 ) were as follows: for incident HF, PAT 1.08 (95% CI, 1.02–1.14) and VAT 1.04 (95% CI, 1.01–1.08); for HF with preserved ejection fraction, PAT 1.13 (95% CI, 1.04–1.21) and VAT 1.07 (95% CI, 1.01–1.13); for mortality, PAT 1.07 (95% CI, 1.03–1.12) and VAT 1.01 (95% CI, 0.98–1.04). SAT was not associated with either outcome. Conclusions High PAT and VAT, but not SAT, were associated with incident HF and HF with preserved ejection fraction, and only PAT was associated with mortality in the fully adjusted models in a longitudinal community cohort of Black participants. Future studies may help understand whether changes in regional adiposity improves HF, particularly HF with preserved ejection fraction, risk predictions. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT00005485.

Abstract MP58: Racial Residential Segregation is Associated With Worse Cardiovascular Health in African American Adults: The Jackson Heart Study

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Sharrelle Barber ◽  
Kiarri Kershaw ◽  
Xu Wang ◽  
Mario Sims ◽  
Julianne Nelson ◽  
...  
Keyword(s):  
African American ◽  
African Americans ◽  
Residential Segregation ◽  
Cardiovascular Health ◽  
Jackson Heart Study ◽  
Racial Residential Segregation ◽  
African American Adults ◽  
Heart Study ◽  
Neighborhood Environments ◽  
The Impact

Introduction: Racial residential segregation results in increased exposure to adverse neighborhood environments for African Americans; however, the impact of segregation on ideal cardiovascular health (CVH) has not been examined in large, socioeconomically diverse African American samples. Using a novel spatial measure of neighborhood-level racial residential segregation, we examined the association between segregation and ideal CVH in the Jackson Heart Study (JHS). Hypothesis: Racial residential segregation will be associated with worse cardiovascular health among African American adults. Methods: The sample included 4,354 men and women ages 21-93 from the baseline exam of the JHS (2000-2004). Racial residential segregation was assessed at the census-tract level. Data on racial composition (% African American) from the 2000 US Census was used to calculate the local G i * statistic- a spatially-weighted z-score that represents how much a neighborhood’s racial/ethnic composition deviates from the larger metropolitan area. Ideal CVH was assessed using the AHA Life’s Simple Seven (LS7) index which includes 3 behavioral (nutrition, physical activity, and smoking) and 4 biological (systolic BP, glucose, BMI, and cholesterol) metrics of CVH. Multivariable regression models were used to test associations between segregation and the LS7 index continuously (range: 0-14) and categorically (Inadequate: 0-4; Average: 5-9; and Optimal: 10-14). Covariates included age, sex, income, education, and insurance status. Results: The average LS7 summary score was 7.03 (±2.1) and was lowest in the most racially segregated neighborhood environments (High Segregation: 6.88 ±2.1 vs. Low Segregation: 7.55 ±2.1). The prevalence of inadequate CVH was higher in racially segregated neighborhoods (12.3%) compared to neighborhoods that were the least segregated (6.9%). After adjusting for key socio-demographic characteristics, racial residential segregation was inversely associated with ideal CVH (B=-0.041 ±0.02, p=0.0146). Moreover, a 1-SD unit increase in segregation was associated with a 6% increased odds of having inadequate CVH (OR: 1.06, 95% CI: 1.00-1.12, p=0.0461). Conclusion: In conclusion, African Americans in racially segregated neighborhoods are less likely to achieve ideal CVH even after accounting for individual-level factors. Policies aimed at restricting housing segregation/discrimination and/or structural interventions designed to improve neighborhood environments may be viable strategies to improving CVH in this at-risk population.

scholarly journals Association of physical activity and heart failure with preserved vs. reduced ejection fraction in the elderly: the Framingham Heart Study

2013 ◽  
Vol 15 (7) ◽  
pp. 742-746 ◽  
Author(s):  
Elisabeth Kraigher-Krainer ◽  
Asya Lyass ◽  
Joseph M. Massaro ◽  
Douglas S. Lee ◽  
Jennifer E. Ho ◽  
...  
Keyword(s):  
Physical Activity ◽  
Heart Failure ◽  
Ejection Fraction ◽  
Framingham Heart Study ◽  
The Elderly ◽  
Reduced Ejection Fraction ◽  
Heart Study
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