Abstract P258: Prevalence of Metabolically Healthy Obesity in US Adult Population: NHANES 1999-2014

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Tingting Liu ◽  
Changwei Li ◽  
Shengxu Li
Keyword(s):  
Central Obesity ◽  
Adult Population ◽  
Density Lipoprotein ◽  
Female Gender ◽  
Obesity Prevalence ◽  
Metabolically Healthy Obesity ◽  
Health And Nutrition ◽  
Younger Age ◽  
Metabolically Healthy ◽  
The U.S

Background: Obesity prevalence has been increasing while cardiometabolic mortality has been decreasing. The reasons for this paradox are not fully understood. Aim: To test the hypothesis that the prevalence of metabolically healthy obesity (MHO) in the U.S. adult population increases over time. Methods: The study included 16,459 participants of the National Health and Nutrition Examination Survey (NHANES) 1999-2014. MHO was defined as central obesity (waist circumference≥102 cm for men and ≥88 cm for women) without any of the following conditions: elevated levels of blood pressure (<125/85 mm Hg), glucose (<100 mg/dL), and triglycerides (<150 mm/dL), reduced levels of high-density lipoprotein cholesterol (≥40 mg/dL for men and ≥50 mg/dL for women), and any medication use for high cholesterol, hypertension, or diabetes. Results: The prevalence of central obesity increased from 45.17% in 1999-2000 to 56.72% in 2013-2014 (P=0.003). MHO prevalence increased from 4.95% in 1999-2000 to 8.92% in 2013-2014. Among those with central obesity, the proportion of MHO increased from 11.0% in 1999-2000 to 15.7% in 2013-2014. Female gender, a younger age, being Hispanic and non-Hispanic Black, and high education (some college or above) were associated with higher prevalence of MHO. Conclusions: While the prevalence of central obesity in the U.S. population has increased, the prevalence of MHO and the proportion of MHO among those who are centrally obese have also increased since 1999, which may partly contribute to the paradox between increased obesity prevalence and reduced cardiometabolic mortality.

Comparison between metabolically healthy obesity and metabolically unhealthy obesity by different definitions among Mexican children

2020 ◽  
Vol 33 (2) ◽  
pp. 215-222 ◽  
Author(s):  
María Lola Evia-Viscarra ◽  
Rodolfo Guardado-Mendoza
Keyword(s):  
Blood Pressure ◽  
Family Background ◽  
Density Lipoprotein ◽  
Model Assessment ◽  
Metabolically Healthy Obesity ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Mexican Children ◽  
Metabolically Healthy ◽  
Metabolically Unhealthy Obesity

AbstractBackgroundThere is no consensus on the definition of metabolically healthy obesity (MHO) and the diagnostic criteria in children.ObjectivesTo estimate the prevalence of MHO and compare clinical and biochemical characteristics between MHO and metabolically unhealthy obesity (MUO), and to evaluate the association between MUO and cardiovascular disease (CVD) risk, anthropometrics and family background using different definitions in children.MethodsThis was a cross-sectional study. Participants included 224 obese children between the years 2007 and 2017. MHO was defined by three different criteria: (i) absence of metabolic syndrome (MHO-MS), (ii) no insulin resistance (IR) by homeostatic model assessment (HOMA) <3.16 cut-off (MHO-IR3.16) and (iii) absence of IR at <95th percentile for Mexican children (MHO-95th).ResultsThe prevalence of MHO-MS, MHO-IR3.16 and MHO-IR95th was 12.9%, 56.3% and 41.5%, respectively. The prevalence of simultaneous MHO-MS plus MHO-IR95th was 5.36%. Children with MHO-MS vs. MUO-MS showed lower height, weight and body mass index (BMI) percentiles; MHO-IR3.16 vs. MUO-IR3.16 showed lower age, acanthosis, Tanner, waist circumference (WC), waist-to-height ratio (WHtR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and glucose; and MHO-IR95th vs. MUO-IR95th showed lower acanthosis, WC, DBP, glucose and high high-density lipoprotein cholesterol (HDL-C). MUO-MS was associated with WC > 90th, type 2 diabetes mellitus (T2DM) in first-degree relatives and obesity in siblings. MUO-IR3.16 was associated with pubertal stages, WC > 90th, WHtR > 0.55 and fasting hyperglycemia. MUO-IR95th was associated with WHtR > 0.55 and HDL < 10th. MHO-MS and MHO-IR3.16 or MHO-IR95th did not have agreement.ConclusionsThe prevalence of MHO varied depending on the definition, although the real MHO with no MS or IR is very low. Low DBP and high HDL-C in MHO were present in any definition. Association of MUO with anthropometric, biochemical and family background differs across definitions.

scholarly journals Metabolically healthy obesity: predictors of transformation to unhealthy phenotype in St Petersburg population (according to the ESSE-RF study)

2021 ◽  
Vol 27 (3) ◽  
pp. 279-290
Author(s):  
M. A. Boyarinova ◽  
O. P. Rotar ◽  
A. M. Erina ◽  
N. A. Paskar ◽  
A. S. Alieva ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Uric Acid ◽  
Waist Circumference ◽  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Metabolically Healthy Obesity ◽  
Metabolically Healthy ◽  
Over Time

Objective. The purpose of the study was to determine the dynamics of the metabolically healthy obesity (MHO) status according to the Meigs criteria, and to establish the predictors of the transformation of healthy obesity phenotype into an unhealthy (MUHO) one in the population of residents of St Petersburg (Russia) at 6,5-year follow-up. Design and methods. Within the epidemiology study ESSE-RF a random sample of 1600 St Petersburg inhabitants stratified according to gender and age was formed. Examination of participants included anthropometry with measurement of waist circumference and calculation of body mass index (BMI), measurement of blood pressure (BP), fasting blood glucose, insulin (index of insulin resistance was calculated), creatinine, cortisol, lipid spectrum, C-reactive protein, adiponectin, leptin, and uric acid. Meigs MHO criteria (2006) were used in obese subjects (BMI > 30 kg/m²). Obese patients, who were identified as metabolically healthy in 2012–2013, were invited for follow-up in 2018–2019. Results. At the first stage obesity was diagnosed in 430 (26,9 %) participants, according to the BMI, 116 (27,0 %) of them were metabolically healthy according to the Meigs criteria. At follow-up, 44,4% individuals with the MHO phenotype transformed to the MUHO category on average after 6,5 years. Individuals who retained the MHO phenotype over time had significantly lower baseline systolic BP and diastolic BP levels, more favorable lipid levels and lower levels of uric acid, insulin, and index of insulin resistance. Glucose increase by every 0,5 mmol/l and higher was associated with elevated probability of transformation MHO to MUHO phenotype by 10,9 times (adjusted for sex and age). Conclusions. Significantly higher levels of BP, insulin resistance, low density lipoprotein and uric acid at baseline, as well as an increase in glucose levels over time, were associated with the transformation of the metabolically healthy to the unhealthy phenotype in obese individuals at 6,5-year follow-up. In all individuals with the MHO phenotype, there was a significant increase in waist circumference over time, accompanied by an increase in BMI only in those who transformed into the MUHO status.

scholarly journals Associations of Relative Humidity and Lifestyles with Metabolic Syndrome among the Ecuadorian Adult Population: Ecuador National Health and Nutrition Survey (ENSANUT-ECU) 2012

2020 ◽  
Vol 17 (23) ◽  
pp. 9023
Author(s):  
Christian F. Juna ◽  
Yoon Hee Cho ◽  
Dongwoo Ham ◽  
Hyojee Joung
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Relative Humidity ◽  
Adult Population ◽  
Menopausal Status ◽  
Density Lipoprotein ◽  
High Relative Humidity ◽  
Nutrition Survey ◽  
Health And Nutrition ◽  
Activity Promotion

The effects of the physical environment on metabolic syndrome (MetS) are still largely unexplained. This study aimed to analyze the associations of relative humidity of residence, lifestyles, and MetS among Ecuadorian adults. Data from 6024 people aged 20 to 60 years were obtained from an Ecuador national population-based health and nutrition survey (i.e., ENSANUT-ECU, 2012) and the mean annual relative humidity (%) from the Ecuador National Institute for Meteorology and Hydrology (2012). Odds ratio (OR) with 95% confidence intervals (CI) for MetS according to groups of relative humidity were calculated using multiple logistic regression. Living in high relative humidity (>80%) increased ORs of reduced high-density lipoprotein (HDL) cholesterol (1.25; 95 % CI, 1.06–1.56) and MetS (OR = 1.20; 95 % CI,1.01–1.42) in women. Furthermore, physically active men living in high relative humidity showed lower OR of elevated triglycerides (0.56; 95 % CI,0.37–0.85) while menopausal women living in high relative humidity showed increased ORs of MetS (5.42; 95 % CI, 1.92–15.27), elevated blood pressure (3.10; 95 % CI, 1.15–8.35), and increased waist circumference (OR = 1.34; 95 % CI, 1.09–1.63). Our results show that residence in high relative humidity and menopausal status increase ORs of MetS and its components in Ecuadorian women; however, physical activity significantly reduces the OR of elevated triglycerides in men. The obtained findings may help make public health policies regarding environmental humidity management, nutritional education, menopausal care, and physical activity promotion to prevent the onset of MetS among Ecuadorian adults.

Sign in / Sign up

Export Citation Format

Share Document