Abstract P610: Ten-Year International Temporal Variations in Age-Standardized Stroke-Related Mortality in Men and Women

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Suzie Ouellet ◽  
Ahmed Alturki ◽  
Mariam Marafi ◽  
Theodore Wein ◽  
Lucy Vieira ◽  
...  

Background: Stroke is one of the leading causes of mortality worldwide. During the last decade, there have been several improvements in stroke-related care such as raising public awareness for early presentation, lifestyle modification, thrombolytic therapy and endovascular therapy. We aimed to evaluate the potential changes in global stroke-related mortality following these innovations. Methods: We completed a systematic review of all population-based cohort studies published during the last two decades (2000-2020). We retained all studies which reported age-adjusted and sex-specific stroke-related mortality. We grouped the countries into: developed countries with predominant White population* (Canada, United States of America, Western Europe, Australia, New Zealand), Eastern Europe, Latin America, and Asia. For each of the region, we compared the median stroke-related mortality during the decade 2010 to the stroke-related mortality of the 2000 decade. Results: Of 210 articles screened, there were eight studies that reported population-based age-standardized and sex-specific stroke-related mortality in 47 countries. We presented the international secular variations in sex-specific stroke-related mortality in Figure 1. We noted significant temporal decreases in age-standardized stroke-related mortality for both men and women in all regions except for Eastern European women and Asian men. Globally, the stroke-related mortality decreased from 40.0 to 31.7 and from 31.6 to 22.8 per 100,000 for men and women, respectively The reductions of stroke-related deaths approximated 22% and 29%, for men and women, respectively. Conclusion: Despite its temporal decrease in most regions, the lack of reduction in stroke-related mortality of Eastern European women and Asian men are noteworthy. Future research is needed to decrease the stroke-related mortality in these high-risk populations. *: As defined by the International Monetary Fund

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Suzie Ouellet ◽  
Ahmed AlTurki ◽  
Mariam Marafi ◽  
Theodore Wein ◽  
Lucy Vieira ◽  
...  

Background: Stroke is one of the leading causes of mortality worldwide. We aimed to evaluate the international variations in stroke-related mortality in men and women. Methods: We completed a systematic review of all population-based cohort studies published during the decade 2010-2020. We retained only studies which reported age-adjusted and sex-specific stroke-related all-cause mortality (per 100 000 population). We computed the median sex-specific stroke-related mortality for each of the following group of countries: developed countries (as defined by the International Monetary Fund) with predominantly white population (Canada, United States of America, Western Europe, Australia, New Zealand), Eastern Europe, Latin America, Asia and Africa. We compared stroke-related mortality between women and men and between regions. Results: Of the 210 articles screened, there were seven studies which reported population-based age-standardized and sex-specific stroke-related mortality in 57 countries. We presented the most recent age-adjusted and sex-specific stroke-related mortality medians (and 25 th and 75 th percentiles) in Figure 1. Globally, we observed a significantly lower stroke-related mortality rate in women compared to men (23.6 and 30.8, respectively) (p-value = 0.007). Age-adjusted stroke-related mortality was the highest for both sexes in Eastern Europe, followed by the African rates. Age-adjusted stroke-related mortality was the lowest for both men and women (p<0.0001) in developed countries with predominantly white population compared to the other regions. Conclusions: There were marked international variations in the age-adjusted stroke-related mortality for both men and women. The high stroke-related mortality in Eastern Europe and Africa should motivate further improvement in stroke care in these regions. Finally, future research is needed to understand and decrease the sex-related difference in stroke-related mortality.


2009 ◽  
Vol 21 (4) ◽  
pp. 487-496 ◽  
Author(s):  
Charumathi Sabanayagam ◽  
Anoop Shankar ◽  
Seang Mei Saw ◽  
E. Shyong Tai ◽  
Tien Yin Wong

In developed countries in the West, lower socioeconomic status (SES) is associated with a higher prevalence of overweight/obesity. The authors examined the association between SES defined by education and income and overweight/obesity in a population-based cohort of 2807 individuals of Malay ethnicity (age 40-80 years, 51% women) in Singapore. The prevalence of overweight/ obesity (body mass index ≥25 kg/m2) in men and women was 50.4% and 65.1%, respectively. In women, the prevalence of overweight/obesity increased with lower levels of education and income. Compared with the higher categories of SES, the odds ratio (95% confidence interval) of overweight/obesity in women was 1.42 (1.06-1.89) for education and 2.08 (1.33-3.26) for income. In contrast, in men, the prevalence of overweight/obesity decreased with lower levels of education and income ( P interaction by gender <.05 for all SES variables). Lower SES was positively associated with overweight/obesity in Malay women, and the association was in the opposite direction in Malay men.


2015 ◽  
Vol 38 (1) ◽  
pp. 6-13 ◽  
Author(s):  
Ervin Toçi ◽  
Genc Burazeri ◽  
Sokol Myftiu ◽  
Kristine Sørensen ◽  
Helmut Brand

1953 ◽  
Vol 51 (3) ◽  
pp. 386-404 ◽  
Author(s):  
F. P. Ellis

The majority of sedentary lightly clad acclimatized European men and women in Singapore are reasonably comfortable in relation to their indoor thermal environment provided the effective temperature does not exceed 78° F. or fall below 73° F.European women, who were, however, older as a group than the other subjects, preferred rather cooler conditions than European men or Asian men and women.There were considerable variations between individuals in their comfort tolerance for various levels of warmth, but the average opinion of one individual was usually consistent provided sufficient votes were collected to provide an adequate sample at each level of warmth.When the dry-bulb temperature was above 83° F., increasing the average air movement from a still to a more turbulent condition added to the comfort of the majority of European men and women. When the temperature was below 83° F. for men and 81° F. for women, moderately good air movement was rather less comfortable than slight air movement; whereas below 77° F. still air was more comfortable than slight or moderate air movement. Increasing the air movement within a compartment can thus be used for combating thermal discomfort only within a limited range of warmth, but within that range it is extremely useful.Two groups of naval ratings who had been living in a warship in a tropical climate were reasonably comfortable at similar levels of warmth to the men in Singapore, but they were less tolerant of levels of warmth above the comfort zone.


2020 ◽  
Vol 20 (5) ◽  
pp. 329-337
Author(s):  
MinJi Lee ◽  
Gunhui Chung

Research shows that disasters affect women more adversely than men especially in developing countries due to differences in socio-cultural customs or physical condition. However, in developed countries, not much difference was found in the percentage of male and female victims of disaster. In South Korea, disasters cause severe damage almost every year, thus the public interest in disaster and safety management is increasing. However, due to insufficient data, it is difficult to analyze whether women suffer more severely than men or not. Therefore, in this study, we reviewed Korea’s disaster management laws and guidelines. In addition, a questionnaire survey was implemented to analyze the level of the public awareness related to disasters and safety management. A total of 489 adults participated in the survey. As a result, it was found that both men and women were not well aware of the possibility of a disaster, and needed to be educated about the locations of shelters and evacuation procedures. Gender analysis showed significant differences in male and female responses concerning some questions. For example, women found it difficult to access disaster and safety management education. Nevertheless, men and women showed similar willingness to participate in disaster and safety management education and training. Therefore, disaster and safety management education programs should be developed and implemented more actively. In addition, it was suggested that sex and age of the victims should be reported and female investigators should be included in the disaster damage investigation team.


2011 ◽  
Author(s):  
Alefiyah Z. Pishori ◽  
Michelle Williams ◽  
Bede Agocha ◽  
Seth J. Schwartz

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
S Mehta ◽  
R Botelho ◽  
F Fernandez ◽  
F Feres ◽  
A Abizaid ◽  
...  

Abstract Background The Latin America Telemedicine Infarct Network (LATIN) has exploited the remarkable competence of telemedicine for remote guidance. In doing so, LATIN created a mammoth population-based AMI network that employed experts located several hundred miles away to guide the reperfusion strategies for almost 800,000 screened patients. In this pioneering project, telemedicine was initially utilized to guide AMI management within national confines. We speculated whether LATIN telemedicine navigation could outstrip countrywide borders. Purpose To maximally harness the vast possibilities of telemedicine for improving AMI care. Methods During its pilot phase, LATIN began as a hub and spoke, AMI system in Colombia where 20 spokes (small community health centers and rural clinics) were configured with 3 hubs that could perform Primary PCI. These sites were linked through web-based connectivity. Expert cardiologists, located 50–250 miles away in Bogota, Colombia, used sophisticated telemedicine platforms for urgent EKG diagnosis and teleconsultation of the entire AMI process. Based upon the duration of chest pain and travel time to the hub, these experts guided patients through guideline-based strategies of thrombolysis, pharmaco invasive management or primary PCI. Efficiency of the telemedicine process was measured with the new metric of time to telemedicine diagnosis (TTD). Cloud computing, GPS navigation, and numerous business intelligent tools were gradually incorporated into LATIN telemedicine. As systems became more scalable, the program was expanded to Brazil, where LATIN flourished. Over the last 18 months, LATIN telemedicine capabilities have been pressed across national boundaries. Presently, all 82 LATIN centers in Mexico are guided by experts located in Bogota, Colombia and the 7 Argentina centers channeled through Santiago, Chile. Results 784,947 patients were screened for AMI at 350 LATIN centers (Brazil 143, Colombia 118, Mexico 82, Argentina 7). Navigation pathways are depicted in the attached figure. TTD remains extremely low in all four countries, and comparable efficiency and tele-accuracy have been achieved. With expanded geographic reach, 8,448 (1.08%) patients were diagnosed with STEMI and 3,911 (46.3%) urgently reperfused, including 3,049 (78%) with Primary PCI. Time to TTD ranged between 2.8 to 5.8 minutes, with a mean of 3.5 min. Tele-accuracy was 98.5%, D2B 51 min, and in-hospital mortality 5.2%. Various other comparative metrics for the 4 countries are being gathered and will be available at the time of presentation. Conclusions LATIN demonstrates the robust ability of telemedicine to transcend national boundaries to guide AMI management. This strategy can be adopted in under-developed countries in Asia and Africa to provide an umbrella of AMI care for the millions of disadvantaged patients.


2020 ◽  
Vol 47 (1) ◽  
pp. 207-236
Author(s):  
Meredith L. Woehler ◽  
Kristin L. Cullen-Lester ◽  
Caitlin M. Porter ◽  
Katherine A. Frear

Substantial research has documented challenges women experience building and benefiting from networks to achieve career success. Yet fundamental questions remain regarding which aspects of men’s and women’s networks differ and how differences impact their careers. To spur future research to address these questions, we present an integrative framework to clarify how and why gender and networks—in concert—may explain career inequality. We delineate two distinct, complementary explanations: (1) unequal network characteristics (UNC) asserts that men and women have different network characteristics, which account for differences in career success; (2) unequal network returns (UNR) asserts that even when men and women have the same network characteristics, they yield different degrees of career success. Further, we explain why UNC and UNR emerge by identifying mechanisms related to professional contexts, actors, and contacts. Using this framework, we review evidence of UNC and UNR for specific network characteristics. We found that men’s and women’s networks are similar in structure (i.e., size, openness, closeness, contacts’ average and structural status) but differ in composition (i.e., proportion of men, same-gender, and kin contacts). Many differences mattered for career success. We identified evidence of UNC only (same-gender contacts), UNR only (actors’ and contacts’ network openness, contacts’ relative status), neither UNC nor UNR (size), and both UNC and UNR (proportion of men contacts). Based on these initial findings, we offer guidance to organizations aiming to address inequality resulting from gender differences in network creation and utilization, and we present a research agenda for scholars to advance these efforts.


Eye ◽  
2021 ◽  
Author(s):  
Sana Hamid ◽  
Parul Desai ◽  
Pirro Hysi ◽  
Jennifer M. Burr ◽  
Anthony P. Khawaja

AbstractEffective population screening for glaucoma would enable earlier diagnosis and prevention of irreversible vision loss. The UK National Screening Committee (NSC) recently published a review that examined the viability, effectiveness and appropriateness of a population-based screening programme for primary open-angle glaucoma (POAG). In our article, we summarise the results of the review and discuss some future directions that may enable effective population screening for glaucoma in the future. Two key questions were addressed by the UK NSC review; is there a valid, accurate screening test for POAG, and does evidence exist that screening reduces morbidity from POAG compared with standard care. Six new studies were identified since the previous 2015 review. The review concluded that screening for glaucoma in adults is not recommended because there is no clear evidence for a sufficiently accurate screening test or for better outcomes with screening compared to current care. The next UK NSC review is due to be conducted in 2023. One challenge for POAG screening is that the relatively low disease prevalence results in too many false-positive referrals, even with an accurate test. In the future, targeted screening of a population subset with a higher prevalence of glaucoma may be effective. Recent developments in POAG polygenic risk prediction and deep learning image analysis offer potential avenues to identifying glaucoma-enriched sub-populations. Until such time, opportunistic case finding through General Ophthalmic Services remains the primary route for identification of glaucoma in the UK and greater public awareness of the service would be of benefit.


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