Biosynthesis of silver nanoparticles, especially fungal mediated method is given attention in the development of new drugs for
resistance pathogens, molecular diagnosis, drug delivery therapy and in catalytic sensor due to its cost effective, none toxicity and
eco-friendly. The present study focused on the fungal mediated biosynthesis of silver nanoparticles using Aspergillus terrues strain
(MTCC 9618). The synthesized nanoparticles was monitored by spectrophotometer SEM, XRD and its band gap was determined
by Tuac equation. After while the fungal crude cells was exposed to 5mM silver nitrate the reduction reaction was recorded
according to red shift colorchange. Based on ultra violet spectrophotometeran absorbance was recorded in a distinct pick around
430nm - 450nm and also the band gab was determined using Tuac equationsuch that 2.08eV, 2.02eV, 2.0eV and 1.96eV at about
10min, 30min, 12h and 24h respectively. The AgNPs coated cotton fabrics was developed through direct exposed to extracellular
metabolites and 100ppm colloidal solution of AgNPs. The antimicrobial efficacy of the synthesized AgNPs coted cotton fabrics against
gram positive Hospital staphylococcus aureus pathogenstrains was conducted by disk diffusion assay. In which the antimicrobial
efficacy of coated cotton-Ag against human pathogens was proofed how the staphylococcus aureus had susceptible too and (16mm)
zone of inhibition was recorded. Based on disk diffusion assay at 10ug/mL minimum inhibition concentration (MIC)10.5 mm
inhibition zone was noted consequently, this study accomplished that Aspergillus terreus strain mediated biosynthesis of silver
nanoparticles is cost effective, time saving, eco-friendly and small spherical (<10nm) had produced against to Physio-chemical
means. The bio-synthesized silver nanoparticles cotton fabrics publicized that a higher efficacy of antimicrobial activity against
staphylococcus aureus and the result was considerable suggested in widely range used in textile and pharmaceutical industries
to enrich durability, strength, quality of products against a clinical pathogens application as well bad odor and spoilage of dusts
from fabrics.
Comparative evaluation of antimicrobial efficacy of silver nanoparticles and 2% chlorhexidine gluconate when used alone and in combination assessed using agar diffusion method: An In vitro study
