scholarly journals Development of salience-driven and visually-guided eye movement responses

2016 ◽  
Vol 16 (5) ◽  
pp. 18 ◽  
Author(s):  
Marlou J. G. Kooiker ◽  
Johannes van der Steen ◽  
Johan J. M. Pel
Keyword(s):  
Eye Movement ◽  
Visually Guided

Abstract W P140: Post-stroke Oculomotor Abnormalities evident during Objective Eye Tracking but Not under Clinical Assessment

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
John-Ross Rizzo ◽  
Todd Hudson ◽  
Briana Kowal ◽  
Michal Wiseman ◽  
Preeti Raghavan
Keyword(s):  
Motor Control ◽  
Eye Movements ◽  
Eye Movement ◽  
Oculomotor Control ◽  
Healthy Controls ◽  
Visually Guided ◽  
Stroke Patients ◽  
Movement Execution ◽  
Post Stroke ◽  
Control Post

Introduction: Visual abnormalities and manual motor control have been studied extensively after stroke, but an understanding of oculomotor control post-stroke has not. Recent studies have revealed that in visually guided reaches arm movements are planned during eye movement execution, which may contribute to increased task complexity. In fact, in healthy controls during visually guided reaches, the onset of eye movement is delayed, its velocity reduced, and endpoint errors are larger relative to isolated eye movements. Our objective in this experiment was to examine the temporal properties of eye movement execution for stroke patients with no diagnosed visual impairment. The goal is to improve understanding of oculomotor control in stroke relative to normal function, and ultimately further understand its coordination with manual motor control during joint eye and hand movements. We hypothesized that stroke patients would show abnormal initiation or onset latency for saccades made in an eye movement task, as compared to healthy controls. Methods: We measured the kinematics of eye movements during point-to-point saccades; there was an initial static, fixation point and the stimulus was a flashed target on a computer monitor. We used a video-based eye tracker for objective recording of the eye at a sampling frequency of 2000 Hz (SR Research, Eyelink). 10 stroke subjects, over 4 months from injury and with no diagnosed visual impairment, and 10 healthy controls completed 432 saccades in a serial fashion. Results: Stroke patients had significantly faster onset latencies as compared to healthy controls during saccades (99.5ms vs. 245.2ms, p=0.00058). Conclusion: A better understanding of the variations in oculomotor control post-stroke, which may go unnoticed during clinical assessment, may improve understanding of how eye control synchronizes with arm or manual motor control. This knowledge could assist in tailoring rehabilitative strategies to amplify motor recovery. For next steps, we will perform objective eye and hand recordings during visually guided reaches post-stroke to better understand the harmonization or lack thereof after neurologic insult.

Visually guided saccade versus eye-hand reach: contrasting neuronal activity in the cortical supplementary and frontal eye fields

1996 ◽  
Vol 75 (5) ◽  
pp. 2187-2191 ◽  
Author(s):  
H. Mushiake ◽  
N. Fujii ◽  
J. Tanji
Keyword(s):  
Eye Movement ◽  
Neuronal Activity ◽  
Motor Task ◽  
Oculomotor Control ◽  
Frontal Eye Field ◽  
Frontal Eye Fields ◽  
Saccadic Eye Movement ◽  
Visually Guided ◽  
Supplementary Eye Field ◽  
Eye Field

1. We studied neuronal activity in the supplementary eye field (SEF) and frontal eye field (FEF) of a monkey during performance of a conditional motor task that required capturing of a target either with a saccadic eye movement (the saccade-only condition) or with an eye-hand reach (the saccade-and-reach condition), according to visual instructions. 2. Among 106 SEF neurons that showed presaccadic activity, more than one-half of them (54%) were active preferentially under the saccade-only condition (n = 12) or under the saccade-and-reach condition (n = 45), while the remaining 49 neurons were equally active in both conditions. 3. By contrast, most (97%) of the 109 neurons in the FEF exhibited approximately equal activity in relation to saccades under the two conditions. 4. The present results suggest the possibility that SEF neurons, at least in part, are involved in signaling whether the motor task is oculomotor or combined eye-arm movements, whereas FEF neurons are mostly related to oculomotor control.

4. Adaptive Gaze Control in an Observational Learning Task

2016 ◽  
Author(s):  
James Kim
Keyword(s):  
Eye Movement ◽  
Observational Learning ◽  
Eye Gaze ◽  
Relevant Information ◽  
Learning Task ◽  
Gaze Control ◽  
Visually Guided ◽  
Object Condition ◽  
Learning Tasks ◽  
Different Types

The purpose of this study was to examine factors that influence how people look at objects they will have to act upon while watching others interact with them first. We investigated whether including different types of task-relevant information into an observational learning task would result in participants adapting their gaze towards an object with more task-relevant information. The participant watched an actor simultaneously lift and replace two objects with two hands then was cued to lift one of the two objects. The objects had the potential to change weight between each trial. In our cue condition, participants were cued to lift one of the objects every single time. In our object condition, the participants were cued equally to act on both objects; however, the weights of only one of the objects would have the potential to change. The hypothesis in the cue condition was that the participant would look significantly more at the object being cued. The hypothesis for the object condition was that the participant would look significantly more (i.e. adapt their gaze) at the object changing weight. The rationale behind this is that participants will learn to allocate their gaze significantly more towards that object so they can gain information about its properties (i.e. weight change). Pending results will indicate whether or not this occurred, and has implications for understanding eye movement sequences in visually guided behaviour tasks. The outcome of this study also has implications for the mechanisms of eye gaze with respect to social learning tasks. 

Role of the Oculomotor Vermis in Generating Pursuit and Saccades: Effects of Microstimulation

1998 ◽  
Vol 80 (4) ◽  
pp. 2046-2062 ◽  
Author(s):  
R. J. Krauzlis ◽  
F. A. Miles
Keyword(s):  
Eye Movements ◽  
Eye Movement ◽  
Transition Point ◽  
Contralateral Side ◽  
Movement Behavior ◽  
Visually Guided ◽  
Ipsilateral Side ◽  
Oculomotor Vermis ◽  
Eye Velocity

Krauzlis, R. J. and F. A. Miles. Role of the oculomotor vermis in generating pursuit and saccades: effects of microstimulation. J. Neurophysiol. 80: 2046–2062, 1998. We studied the eye movements evoked by applying small amounts of current (2–50 μA) within the oculomotor vermis of two monkeys. We first compared the eye movements evoked by microstimulation applied either during maintained pursuit or during fixation. Smooth, pursuitlike changes in eye velocity caused by the microstimulation were directed toward the ipsilateral side and occurred at short latencies (10–20 ms). The amplitudes of these pursuitlike changes were larger during visually guided pursuit toward the contralateral side than during either fixation or visually guided pursuit toward the ipsilateral side. At these same sites, microstimulation also often produced abrupt, saccadelike changes in eye velocity. In contrast to the smooth changes in eye velocity, these saccadelike effects were more prevalent during fixation and during pursuit toward the ipsilateral side. The amplitude and type of evoked eye movements could also be manipulated at single sites by changing the frequency of microstimulation. Increasing the frequency of microstimulation produced increases in the amplitude of pursuitlike changes, but only up to a certain point. Beyond this point, the value of which depended on the site and whether the monkey was fixating or pursuing, further increases in stimulation frequency produced saccadelike changes of increasing amplitude. To quantify these effects, we introduced a novel method for classifying eye movements as pursuitlike or saccadelike. The results of this analysis showed that the eye movements evoked by microstimulation exhibit a distinct transition point between pursuit and saccadelike effects and that the amplitude of eye movement that corresponds to this transition point depends on the eye movement behavior of the monkey. These results are consistent with accumulating evidence that the oculomotor vermis and its associated deep cerebellar nucleus, the caudal fastigial, are involved in the control of both pursuit and saccadic eye movements. We suggest that the oculomotor vermis might accomplish this role by altering the amplitude of a motor error signal that is common to both saccades and pursuit.

scholarly journals Interhemispherically dynamic representation of an eye movement-related activity in mouse frontal cortex

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Takashi R Sato ◽  
Takahide Itokazu ◽  
Hironobu Osaki ◽  
Makoto Ohtake ◽  
Tetsuya Yamamoto ◽  
...  
Keyword(s):  
Eye Movement ◽  
Neural Plasticity ◽  
Calcium Imaging ◽  
Cortical Plasticity ◽  
Motor Recovery ◽  
Compensatory Mechanism ◽  
Visually Guided ◽  
Related Activity ◽  
Two Photon ◽  
Dynamic Representation

Cortical plasticity is fundamental to motor recovery following cortical perturbation. However, it is still unclear how this plasticity is induced at a functional circuit level. Here, we investigated motor recovery and underlying neural plasticity upon optogenetic suppression of a cortical area for eye movement. Using a visually-guided eye movement task in mice, we suppressed a portion of the secondary motor cortex (MOs) that encodes contraversive eye movement. Optogenetic unilateral suppression severely impaired contraversive movement on the first day. However, on subsequent days the suppression became inefficient and capability for the movement was restored. Longitudinal two-photon calcium imaging revealed that the regained capability was accompanied by an increased number of neurons encoding for ipsiversive movement in the unsuppressed contralateral MOs. Additional suppression of the contralateral MOs impaired the recovered movement again, indicating a compensatory mechanism. Our findings demonstrate that repeated optogenetic suppression leads to functional recovery mediated by the contralateral hemisphere.

Eye Movements during Geometrical Problem Solving

Perception ◽  
1997 ◽  
Vol 26 (1_suppl) ◽  
pp. 138-138 ◽  
Author(s):  
J Epelboim ◽  
P Suppes
Keyword(s):  
Eye Movement ◽  
Movement Pattern ◽  
Visually Guided ◽  
Verbal Protocols ◽  
Movement Data ◽  
Cognitive Operations ◽  
New Information ◽  
Problem Solvers ◽  
Simple Features ◽  
Probabilistic Nature

Diagrams are used extensively in posing and solving geometry problems. It is likely that strategies that good problem-solvers have developed for looking at diagrams reflect their reasoning about each problem. This suggested that the eye-movement patterns of geometry experts, observed while they solve problems posed with diagrams, are likely to contain new information about their reasoning. Eye-movement data, collected while subjects solved geometry problems posed as diagrams, were examined. Three subjects participated. Two of the subjects (‘experts’) were skilled at solving geometry problems. The third subject (‘non-expert’) had last solved such problems over 50 years prior to the experiment, and did not know how to proceed on most of the problems. The eye-movement pattern reflected cognitive operations used to solve each problem. Fixation durations depended, to some extent, on cognitive or perceptual processing of features at each gaze location. For example, fixations were longer when gaze was on the angle in question, than when gaze was on other angles or line-segments. Likewise, saccades were made to features that were being considered, as indicated by verbal protocols. Expert subjects combined simple features into more complex, imaginary structures, as was required to solve the problem. They scanned the areas of the diagram that fell within the imagined contours of these structures. The non-expert did not construct such structures. He only scanned visible features of the diagram. Variability in durations of fixations and landing positions of saccades was not due solely to the probabilistic nature of the oculomotor processes. Such processes, however, clearly play an important role in determining the eye-movement pattern in this task, as they do in other visually-guided tasks.

scholarly journals Streamlined sensory motor communication through cortical reciprocal connectivity in a visually guided eye movement task

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Takahide Itokazu ◽  
Masashi Hasegawa ◽  
Rui Kimura ◽  
Hironobu Osaki ◽  
Urban-Raphael Albrecht ◽  
...  
Keyword(s):  
Eye Movement ◽  
Visually Guided ◽  
Sensory Motor

Effect of aging on the accuracy of visually guided saccadic eye movement

1984 ◽  
Vol 16 (4) ◽  
pp. 449-454 ◽  
Author(s):  
Tateo Warabi ◽  
Manabu Kase ◽  
Takamasa Kato
Keyword(s):  
Eye Movement ◽  
Saccadic Eye Movement ◽  
Visually Guided

Saccade initiation and latency deficits after combined lesions of the frontal and posterior eye fields in monkeys

1992 ◽  
Vol 68 (5) ◽  
pp. 1913-1916 ◽  
Author(s):  
J. C. Lynch
Keyword(s):  
Eye Movements ◽  
Eye Movement ◽  
Frontal Eye Field ◽  
Visually Guided ◽  
Before And After ◽  
Combined Lesions ◽  
Eye Field ◽  
Bilateral Lesions

1. Monkeys were trained to perform horizontal visually guided saccades. Latency was measured before and after bilateral lesions of the frontal eye field (FEF) and after combined lesions of both the FEF and the posterior eye field. Destruction of either of these regions alone causes only modest deficits of eye movement, but destruction of both together produces profound oculomotor impairment. The results support the proposal that purposeful eye movements are controlled by a distributed corticocortical network that includes nodes in frontal and parieto-occipital regions.

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