Depressive symptoms, medical illness, and functional status in depressed psychiatric inpatients

1993 ◽  
Vol 150 (6) ◽  
pp. 910-915 ◽  
2001 ◽  
Vol 42 (1) ◽  
pp. 21-36 ◽  
Author(s):  
Heather Uncapher

Cognitive factors such as perceptions of poor health and negative expectancies toward the future may mediate relationships between health variables, depressive symptoms, and suicidal ideation. In this study of risk factors associated with late life suicidal ideation, thirty older psychiatric inpatients were interviewed using standardized instruments. Self-reported symptoms of hopelessness, perceived health, and depression, as well as number of impaired medical illness systems were examined in relation to presence of suicidal thoughts. Several aspects of a cognitive model of suicide were supported using partial correlation and regression analyses. First, patients who were more depressed and suicidal had more negative cognitions than those who were less depressed and not suicidal. Second, depressive symptoms were strongly related to suicidal thoughts even after controlling for the patients' number of impaired illness systems. Third, cognitive factors versus health factors were shown to influence the relationship between depression and suicidal ideation. These findings emphasize the importance of cognitive biases in geriatric suicidal ideation.


Author(s):  
Leonardo Carvalho Silva ◽  
Andressa Silva ◽  
Marcela Ferreira De Andrade Rangel ◽  
Lívia Cristina Guimarães Caetano ◽  
Luci Fuscaldi Teixeira-Salmela ◽  
...  

Author(s):  
Joel R Petashnick ◽  
Amit Shrira ◽  
Yaakov Hoffman ◽  
Yuval Palgi ◽  
Gitit Kavé ◽  
...  

Abstract Objectives The present study examined the longitudinal relationships between subjective age (SA) and future functional status in later life, via depressive symptoms. Additionally, we assessed the role of subjective nearness to death (SNtD) as a potential moderator within these pathways. Methods Older adults (average age 81.14 at T1) were interviewed once a year for three consecutive years (N=224 at T1, N=178 at T2, and N=164 at T3), Participants reported their SA, SNtD, depressive symptoms, and functional status. Additionally, grip strength was employed as an objective measure of functional status. Results Data analysis revealed distinct pathways leading from T1 SA to T3 functional status through T2 depressive symptoms. Moreover, T1 SNtD was found to significantly moderate most of these indirect pathways, so that the mediation model of T1 SA-T2 depressive symptoms-T3 functional status was mostly significant among those who felt closer to death. Discussion The findings contribute to our understanding of the underlying mechanism through which SA predicts long-term functioning sequelae by underscoring the indirect effect of depressive symptoms. They further indicate the importance of gauging the effects of SNtD on these longitudinal relationships. Present results may further contribute to establishing an integrative model for predicting long-term functional outcomes based on older adults' earlier subjective views of aging.


Author(s):  
Myrna M. Weissman ◽  
John C. Markowitz ◽  
Gerald L. Klerman

This chapter describes the tasks of the first few IPT sessions. The therapist’s tasks in the opening sessions are to review the depressive symptoms and make a diagnosis; explain depression as a medical illness and describe treatment options; evaluate the need for medication; review the patient’s “interpersonal inventory”; present a formulation, linking the patient’s illness to an interpersonal focus; make a treatment contract based on the formulation, and explain what to expect in treatment; define the framework and structure of treatment; and give the patient the “sick role.” After this, the work of IPT begins on the defined problem area. In these sessions the therapist focuses consistently on mood and interpersonal interaction. The therapist helps the patient to see the link between them, reinforces adaptive interpersonal functioning, and helps the patient to explore and gain comfort with new options where old strategies have not been working.


2006 ◽  
Vol 80 (2) ◽  
pp. 379-392 ◽  
Author(s):  
Glenn V. Ostir ◽  
Kenneth J. Ottenbacher ◽  
Linda P. Fried ◽  
Jack M. Guralnik

2010 ◽  
Vol 60 (4) ◽  
pp. 301-325 ◽  
Author(s):  
Christian J. Lalive d'Epinay ◽  
Stefano Cavalli ◽  
Luc A. Guillet

This article deals with the following two questions: In very old age, which are the main sources of bereavement? And what are the consequences of such losses on health and on relationships? The findings are based on the complete set of data compiled in the course of the Swiss Interdisciplinary Longitudinal Study on the Oldest Old (SWILSOO), which provided a 10-year follow-up of a first cohort (1994–2004) and a 5-year follow-up of a second (1999–2004). The data revealed that, in very old age, the great majority of the dear ones who died were either siblings or close friends. Taken as a whole, the bereaved suffered a marked and lasting increase in depressive symptoms, together with a short-term deterioration in their functional status; those bereft of a spouse or a child saw their functional status worsen and exhibited enduring depressive symptoms but they also benefited from support in the form of increased interaction; those bereft of siblings only suffered from a mild, short-term deterioration in functional status; those who had lost a close friend suffered a very significant increase in depressive symptoms. In the medium term, most of these effects disappeared, lending weight to the claim that the survivors manage to cope with the misfortunes of life.


2013 ◽  
Vol 33 (8) ◽  
pp. 1973-1979 ◽  
Author(s):  
Mustafa Akif Sariyildiz ◽  
Ibrahim Batmaz ◽  
Mahmut Budulgan ◽  
Mehtap Bozkurt ◽  
Levent Yazmalar ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0245478
Author(s):  
Leonard Turnier ◽  
Michelle Eakin ◽  
Han Woo ◽  
Mark Dransfield ◽  
Trisha Parekh ◽  
...  

Background The purpose of this study was to explore the association between perceived social support and COPD outcomes and to determine whether the associations are mediated by depressive symptoms. Methods Subjects with COPD who were enrolled as part of SPIROMICS were included in this analysis. Questionnaires relating to quality of life, symptom burden, and functional status were administered at annual clinic visits for over a 3 year period. In both cross-sectional and longitudinal analyses, we examined the association of social support as measured by the FACIT-F with COPD outcomes. Cross sectional analyses used multivariable linear or logistic regression, adjusting for covariates. For longitudinal analyses, generalized linear mixed models with random intercepts were used. Models were adjusted with and without depressive symptoms and mediation analyses performed. Results Of the 1831 subjects with COPD, 1779 completed the FACIT- F questionnaire. In adjusted cross-sectional analysis without depressive symptoms, higher perceived social support was associated with better quality of life, well-being, 6 minute walk distance, and less dyspnea. When also adjusting for depressive symptoms, all associations between social support and COPD outcomes were attenuated and no longer statistically significant. Mediation analysis suggested that depressive symptoms explained the majority (> = 85%) of the association between social support and measured COPD outcomes. Results of the longitudinal analysis were consistent with the cross-sectional analyses. There was no association between social support and odds of exacerbations. Conclusion Higher social support was associated with better COPD outcomes across several measures of morbidity including quality of life, respiratory symptoms, and functional status. In addition, these associations were largely attenuated when accounting for depressive symptoms suggesting that the beneficial association of social support with COPD outcomes may be largely mediated by the association between social support and depression. Trial registration SPIROMICS was approved by Institutional Review Boards at each center and all participants provided written informed consent (clinicaltrials.gov: NCT01969344).


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 720-721
Author(s):  
Wingyun Mak ◽  
Orah Burack ◽  
Joann Reinhardt ◽  
Himali Weerahandi ◽  
Benjamin Canter ◽  
...  

Abstract Prior work shows that older adults who establish future care plans have a lower risk of depression. Residents in long-term care may benefit from establishing a do-not-resuscitate (DNR) order when cardiopulmonary resuscitation is unlikely to provide medical benefit. The current study examines whether having a DNR order in place prior to COVID-19 diagnosis was associated with fewer depressive symptoms during the illness course. Residents at a NYC skilled nursing facility with a positive COVID-19 PCR test between 3/1/2020 – 6/1/2020 were included (N=338). The Minimum Data Set (3.0) was used to examine residents’ Patient Health Questionnaire-9 (PHQ-9) scores 1-30 days after diagnosis, functional status, cognition, age, and sex. A retrospective chart review was conducted to determine whether participants had an established DNR, DNI, and/or DNH order before developing COVID-19. Forty-eight percent, 46%, and 12% of participants had a DNR, DNI, or DNH order prior to COVID-19 illness, respectively. Average PHQ-9 score was 1.65 (SD=2.37). A hierarchical regression showed that after controlling for age (β=-.13, p=.06), sex (β=-.08, p=.28), cognition (β=.14, p=.04), and functional status (β=.23, p=.001; R2=.10, p=.001), having a DNR (β=-.22, p=.006) order in place prior to COVID illness was associated with lower endorsement of depressive symptoms during illness (ΔR2=.04, p=.01). Results suggest that establishing a DNR in long-term care residents when appropriate may potentially buffer depressive symptoms during illness in nursing home residents regardless of their age, sex, cognitive abilities, and functional status. Future examination of the underlying mechanism is warranted.


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