scholarly journals Laboratory animals search filter for different literature databases: PubMed, Embase, Web of Science and PsycINFO

2021 ◽  
pp. 002367722110454
Author(s):  
Stevie van der Mierden ◽  
Carlijn R Hooijmans ◽  
Alice HJ Tillema ◽  
Simone Rehn ◽  
André Bleich ◽  
...  
Keyword(s):  
Random Sample ◽  
Systematic Reviews ◽  
Animal Studies ◽  
Web Of Science ◽  
Real Life ◽  
Animal Research ◽  
Laboratory Animals ◽  
Primary Study ◽  
Search Filter ◽  
Search Filters

Systematic reviews are important tools in animal research, but the ever-increasing number of studies makes retrieval of all relevant publications challenging. Search filters aid in retrieving as many animal studies as possible. In this paper we provide updated and expanded versions of the SYRCLE animal filters for PubMed and Embase. We provide the Embase filter for both Embase.com and via Ovid. Furthermore, we provide new animal search filters for Web of Science (WoS) and APA PsycINFO via psycnet.apa.org and via Ovid. Compared with previous versions, the new filters retrieved 0.5–47.1% (19 references for PubMed, 837 for WoS) more references in a real-life example. All filters retrieved additional references, comprising multiple relevant reviews. A random sample from WoS found at least one potentially relevant primary study. These animal search filters facilitate identifying as many animal studies as possible while minimising the number of non-animal studies.

scholarly journals A search filter for increasing the retrieval of animal studies in Embase

2011 ◽  
Vol 45 (4) ◽  
pp. 268-270 ◽  
Author(s):  
Rob B M de Vries ◽  
Carlijn R Hooijmans ◽  
Alice Tillema ◽  
Marlies Leenaars ◽  
Merel Ritskes-Hoitinga
Keyword(s):  
Systematic Reviews ◽  
Animal Studies ◽  
Research Question ◽  
Animal Experiments ◽  
Search Process ◽  
General Requirement ◽  
Search Filter ◽  
Search Filters ◽  
Similar Search

Collecting and analysing all available literature before starting a new animal experiment is important and it is indispensable when writing systematic reviews of animal research. In practice, finding all animal studies relevant to a specific research question turns out to be anything but simple. In order to facilitate this search process, we previously developed a search filter for retrieving animal studies in the most often used biomedical database, PubMed. It is a general requirement for systematic reviews, however, that at least two databases are searched. In this report, we therefore present a similar search filter for a second important database, namely Embase. We show that our filter retrieves more animal studies than (a combination of) the options currently available in Embase. Our search filters for PubMed and Embase therefore represent valuable tools for improving the quality of (systematic) reviews and thereby of new animal experiments.

scholarly journals Translation and validation of PubMed and Embase search filters for identification of systematic reviews, intervention studies, and observational studies in the field of first aid

2021 ◽  
Vol 109 (4) ◽  
Author(s):  
Bert Avau ◽  
Hans Van Remoortel ◽  
Emmy De Buck
Keyword(s):  
Systematic Reviews ◽  
Observational Studies ◽  
Intervention Studies ◽  
First Aid ◽  
Search Filter ◽  
Filter Performance ◽  
Ovid Medline ◽  
Search Filters ◽  
Study Type ◽  
Evidence Summaries

Objective: The aim of this project was to validate search filters for systematic reviews, intervention studies, and observational studies translated from Ovid MEDLINE and Embase syntax and used for searches in PubMed and Embase.com during the development of evidence summaries supporting first aid guidelines. We aimed to achieve a balance among recall, specificity, precision, and number needed to read (NNR).Methods: Reference gold standards were constructed per study type derived from existing evidence summaries. Search filter performance was assessed through retrospective searches and measurement of relative recall, specificity, precision, and NNR when using the translated search filters. Where necessary, search filters were optimized. Adapted filters were validated in separate validation gold standards.Results: Search filters for systematic reviews and observational studies reached recall of ≥85% in both PubMed and Embase. Corresponding specificities for systematic review filters were ≥96% in both databases, with a precision of 9.7% (NNR 10) in PubMed and 5.4% (NNR 19) in Embase. For observational study filters, specificity, precision, and NNR were 68%, 2%, and 51 in PubMed and 47%, 0.8%, and 123 in Embase, respectively. These filters were considered sufficiently effective. Search filters for intervention studies reached a recall of 85% and 83% in PubMed and Embase, respectively. Optimization led to recall of ≥95% with specificity, precision, and NNR of 49%, 1.3%, and 79 in PubMed and 56%, 0.74%, and 136 in Embase, respectively.Conclusions: We report validated filters to search for systematic reviews, observational studies, and intervention studies in guideline projects in PubMed and Embase.com.

scholarly journals VP195 Using The ISSG Search Filter Resource In Health Technology Assessment

2017 ◽  
Vol 33 (S1) ◽  
pp. 240-240
Author(s):  
Kath Wright ◽  
Julie Glanville ◽  
Carol Lefebvre
Keyword(s):  
Randomized Controlled Trials ◽  
Systematic Reviews ◽  
Health Technology ◽  
Controlled Trials ◽  
Health State ◽  
Search Filter ◽  
Utility Values ◽  
Randomized Controlled ◽  
Search Filters ◽  
Health State Utility Values

INTRODUCTION:Information specialists and others searching for Health Technology Assessments (HTAs) can use the ISSG Search Filter resource (SFR) to identify filters to incorporate into search strategies. This can save time and effort when designing searches and create more efficient searches that retrieve fewer and possibly more relevant database records (link available here: https://sites.google.com/a/york.ac.uk/issg-search-filters-resource/home).What are search filters? Search filters are collections of search terms designed to retrieve selections of records from bibliographic databases. Some filters are designed to retrieve records of specific study designs such as randomized controlled trials (RCTs) or systematic reviews; others aim to retrieve records relating to other features or topics such as the age or gender of study participants.Search filters may be designed to be sensitive, precise or balanced between sensitivity and precision.METHODS:When would you use a search filter in HTA? Search filters can be added to search strategies to limit to specific study types, for example, RCTs, mixed methods studies, systematic reviews. They can also be used when searching for other aspects of HTA such as patient views or specific age groups.The ISSG SFR includes sections listing search filters to help identify adverse effects, aetiology, economic evaluations, health state utility values, public views, and quality of life.RESULTS:How are filters used? A search filter is often used in combination with a topic search to restrict the search results to a specific type of record, for example, records reporting health state utility values or records of randomized controlled trials.CONCLUSIONS:Further guidance on the use of search filters can be found in the SuRe Info Search Filters chapter.

scholarly journals Recommendations for Ethical Review of Veterinary Clinical Trials

2021 ◽  
Vol 8 ◽  
Author(s):  
Jessica A. Bertout ◽  
Philippe J. R. Baneux ◽  
Carol K. Robertson-Plouch
Keyword(s):  
United States ◽  
Clinical Trials ◽  
Best Practices ◽  
United States Of America ◽  
Clinical Studies ◽  
Animal Studies ◽  
The United States ◽  
Animal Research ◽  
Laboratory Animals ◽  
Ethical Review

Ethical review of both human and animal research is critical to ensuring that studies are conducted with due regard to the welfare and safety of enrolled subjects and to the integrity of the data. However, differences exist in laws, policies, and best practices between human and animal studies. Ethical review is required for most human studies. While the laws and standards are clear for humans and for laboratory animals, the laws and standards for clinical research for client-owned animals are not as well-defined. Here, we discuss gaps in ethical review of clinical animal research in the United States of America and propose expanded functions for veterinary clinical studies committees as a solution.

scholarly journals Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals

2020 ◽  
Vol 4 (1) ◽  
pp. e100046 ◽  
Author(s):  
Jan Vollert ◽  
Esther Schenker ◽  
Malcolm Macleod ◽  
Anton Bespalov ◽  
Hanno Wuerbel ◽  
...  
Keyword(s):  
Systematic Review ◽  
Animal Studies ◽  
Web Of Science ◽  
Internal Validity ◽  
Relative Effect ◽  
Effect Sizes ◽  
Laboratory Animals ◽  
Preclinical Research ◽  
Sample Size Calculations ◽  
Flow Through

Over the last two decades, awareness of the negative repercussions of flaws in the planning, conduct and reporting of preclinical research involving experimental animals has been growing. Several initiatives have set out to increase transparency and internal validity of preclinical studies, mostly publishing expert consensus and experience. While many of the points raised in these various guidelines are identical or similar, they differ in detail and rigour. Most of them focus on reporting, only few of them cover the planning and conduct of studies. The aim of this systematic review is to identify existing experimental design, conduct, analysis and reporting guidelines relating to preclinical animal research. A systematic search in PubMed, Embase and Web of Science retrieved 13 863 unique results. After screening these on title and abstract, 613 papers entered the full-text assessment stage, from which 60 papers were retained. From these, we extracted unique 58 recommendations on the planning, conduct and reporting of preclinical animal studies. Sample size calculations, adequate statistical methods, concealed and randomised allocation of animals to treatment, blinded outcome assessment and recording of animal flow through the experiment were recommended in more than half of the publications. While we consider these recommendations to be valuable, there is a striking lack of experimental evidence on their importance and relative effect on experiments and effect sizes.

scholarly journals Heart rate variability as a strain indicator for psychological stress for emergency physicians during work and alert intervention: a systematic review

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Beatrice Thielmann ◽  
Robert Pohl ◽  
Irina Böckelmann
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Systematic Reviews ◽  
Web Of Science ◽  
Meta Analysis ◽  
Emergency Physicians ◽  
Inclusion Criteria ◽  
Objective Monitoring ◽  
Prisma Statement ◽  
Health Studies

Abstract Background The workloads of emergency physicians are severe. The prevalence of burnout among emergency physicians is higher than with other physicians or compared to the general population. The analysis of heart rate variability (HRV) is a valid method for objective monitoring of workload. The aim of this paper is to systematically evaluate the literature on heart rate variability as an objective indicator for mental stress of emergency physicians. Methods A systematic literature review examining heart rate variability of emergency physicians in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement for reporting systematic reviews was performed. PubMed, Ovid, Cochrane Libary, Scopus, and Web of Science electronic databases were used. The methodological quality was evaluated by using a modified STARD for HRV. Results Two studies matched the inclusion criteria by using HRV between alert intervention and two other studies were considered that used HRV in other question areas. It showed an adaptation of HRV under stress. The studies were not comparable. Conclusions There is a need for occupational health studies that examine strains and stress of emergency physicians. The well-established parasympathetic mediated HRV parameters seem to be suitable parameters to objectify the stress.

scholarly journals Managing overlap of primary study results across systematic reviews: practical considerations for authors of overviews of reviews

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Carole Lunny ◽  
Dawid Pieper ◽  
Pierre Thabet ◽  
Salmaan Kanji
Keyword(s):  
Case Studies ◽  
Systematic Reviews ◽  
Data Extraction ◽  
Methodological Approach ◽  
Study Data ◽  
Primary Study ◽  
Eligibility Criteria ◽  
Overlapping Data ◽  
Study Results ◽  
Yield Trends

Abstract Background Overviews often identify and synthesise a large number of systematic reviews on the same topic, which is likely to lead to overlap (i.e. duplication) in primary studies across the reviews. Using a primary study result multiple times in the same analysis overstates its sample size and number of events, falsely leading to greater precision in the analysis. This paper aims to: (a) describe types of overlapping data that arise from the same primary studies reported across multiple reviews, (b) describe methods to identify and explain overlap of primary study data, and (c) present six case studies illustrating different approaches to manage overlap. Methods We first updated the search in PubMed for methods from the MOoR framework relating to overlap of primary studies. One author screened the studies titles and abstracts, and any full-text articles retrieved, extracted methods data relating to overlap of primary studies and mapped it to the overlap methods from the MOoR framework. We also describe six case studies as examples of overviews that use specific overlap methods across the steps in the conduct of an overview. For each case study, we discuss potential methodological implications in terms of limitations, efficiency, usability, and resource use. Results Nine methods studies were found and mapped to the methods identified by the MOoR framework to address overlap. Overlap methods were mapped across four steps in the conduct of an overview – the eligibility criteria step, the data extraction step, the assessment of risk of bias step, and the synthesis step. Our overview case studies used multiple methods to reduce overlap at different steps in the conduct of an overview. Conclusions Our study underlines that there is currently no standard methodological approach to deal with overlap in primary studies across reviews. The level of complexity when dealing with overlap can vary depending on the yield, trends and patterns of the included literature and the scope of the overview question. Choosing a method might be dependent on the number of included reviews and their primary studies. Gaps in evaluation of methods to address overlap were found and further investigation in this area is needed.

Neurobiology of premature ejaculation - from animal experiments to evidence- based treatment in humans

2011 ◽  
Vol 26 (S2) ◽  
pp. 2034-2034
Author(s):  
M.D. Waldinger
Keyword(s):  
Premature Ejaculation ◽  
Animal Experiments ◽  
Animal Research ◽  
Laboratory Animals ◽  
Evidence Based ◽  
Female Rat ◽  
Neural Basis ◽  
Behavioral Studies ◽  
Female Wistar Rats ◽  
Lifelong Premature Ejaculation

In the last two decades an increasing number of sexual behavioral studies in laboratory animals has contributed to a better understanding of the neural basis of ejaculatory functioning. In addition, these studies, which mainly involved male and female Wistar rats, elucidated basic mechanisms that underly the psychopharmacology of SSRI-induced ejaculation delay. Notably, a new animal model for premature and retarded ejaculation has been developed. This model has been shown to be of eminent importance for the investigation of ejaculatory disorders. Moreover, it has been proven useful into the investigation of female rat sexual motivation. Translational research translates findings of animal research into human application. Indeed, objective and systematic psychopharmacological research in men with lifelong premature ejaculation yields a remarkable similarity with data that have been found in animals. Sofar, animal research of premature ejaculation remarkably predicts data in men with lifelong PE, on the condition that clinical human research was performed according to evidence based research principles.

scholarly journals Examination of the Clinical Queries and Systematic Review “hedges” in EMBASE and MEDLINE

2014 ◽  
Vol 31 (2) ◽  
pp. 27 ◽  
Author(s):  
Susan M. Bradley
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Major Error ◽  
National Library ◽  
Search Queries ◽  
Search Results ◽  
Quality Control Testing ◽  
Search Filters ◽  
The One ◽  
Clinical Queries

Introduction – This investigation sought to determine whether the methodological search filters in place as Clinical Queries limits in OvidSP EMBASE and OvidSP MEDLINE had been modified from those written by Haynes et al. and whether the translations of these in PubMed and EBSCO MEDLINE were reliable. The translated National Library of Medicine (NLM) Systematic Reviews hedges in place in OvidSP MEDLINE and EBSCO MEDLINE were also examined. Methods – Search queries were run using the Clinical Queries and Systematic Reviews hedges incorporated into OvidSP EMBASE, OvidSP MEDLINE, PubMed, and EBSCO MEDLINE to determine the reliability of these limits in comparison with the published hedge search strings. Results – Five of the OvidSP EMBASE Clinical Queries hedges produced results that were different from the published search strings. Three of the EBSCO MEDLINE and five of the PubMed translated Clinical Queries hedges yielded markedly different results (>10% difference) than those obtained using the OvidSP MEDLINE hedge counterparts. The OvidSP MEDLINE Systematic Reviews subject subset hedge was found to have a major error, which has been corrected. Discussion – Translations of hedges to appropriate syntax for other database platforms may result in significantly different search results. The platform searched should ideally be the one for which the hedges were written and tested. Regardless, the hedges in place may not be the same as the published hedge search strings. Quality control testing is needed to ensure that the hedges in place as limits are the same as those that have been published.

scholarly journals Problemas de coagulação em adultos com síndroma respiratório agudo grave devido a infeção por coronavírus 2 (SARS-CoV-2): uma revisão abrangente

2021 ◽  
Vol 37 (5) ◽  
pp. 421-434
Author(s):  
Susana Pereira Costa ◽  
◽  
Inês Lopes Antunes ◽  
Ana Margarida Gomes ◽  
Cláudia Ho ◽  
...  
Keyword(s):  
Systematic Reviews ◽  
Scoping Review ◽  
Web Of Science ◽  
Scoping Reviews ◽  
Meta Analyses

Objetivos: Resumir as informações publicadas acerca dos problemas de coagulação em adultos com SARS-CoV-2, incluindo características, fisiopatologia, diagnóstico e resposta ao uso profilático ou terapêutico de anticoagulantes ou antiagregantes plaquetários. Métodos: Realizada uma revisão abrangente, de acordo com as guidelines Joanna Briggs Institute Guidelines on Scoping Reviews e Preferred Reporting Items for Systematic Reviews and Meta-Analyses Scoping Review guidelines (PRISMA-ScR). Efetuada pesquisa nas bases de dados MEDLINE®, SciELO® e Web of Science® entre 1 e 2 de maio de 2020. A seleção dos artigos foi dividida em etapas sequenciais considerando: título, resumo e artigo integral. Em cada etapa os artigos foram aceites ou rejeitados tendo em conta os critérios de inclusão e exclusão. Foi feito o mapeamento dos dados e a evidência relevante foi sumarizada. Resultados: Após seleção obtiveram-se 106 artigos. Destes, 36 correspondiam a cartas, 28 a estudos originais, 25 a revisões e 14 a relatos de caso; uma meta-análise, um comentário e um consenso também foram incluídos. Os resultados mostraram associação entre COVID-19 e complicações trombóticas, embora com diferentes tipos de eventos e taxas de frequência. A tríade inflamação, disfunção endotelial e coagulopatia parecem estar subjacentes às alterações fisiopatológicas. As técnicas laboratoriais e de imagem podem ser úteis para uma intervenção adequada. A profilaxia com anticoagulantes parentéricos, preferencialmente heparina de baixo peso molecular (HBPM) em dose intermédia, entre as comummente utilizadas para profilaxia ou tratamento, está indicada em pacientes hospitalizados, especialmente com doença grave. Deve ser mantida por um período variável após a alta, dependendo do doente. A anticoagulação terapêutica parece não diferir de outras situações previamente conhecidas. Conclusões: Várias incertezas persistem na abordagem dos problemas da coagulação em pacientes com infeção por SARS-CoV-2. As informações existentes dizem respeito principalmente ao contexto hospitalar e têm origem em fontes pouco robustas. Assim, são necessários ensaios clínicos aleatorizados e controlados para sustentar as decisões clínicas em todos os estadios.

Sign in / Sign up

Export Citation Format

Share Document