A decision procedure for selecting among proposed automatic analog computer patching systems

SIMULATION ◽  
1969 ◽  
Vol 13 (3) ◽  
pp. 133-145 ◽  
Author(s):  
T.J. Gracon ◽  
J.C. Strauss

In the recent literature, a paper1 and a contract report2 indicate that automatic analog computer patching sys tems have become economically and technologically feasible. In anticipation of the development of a variety of proposed patching systems, a specific decision pro cedure is developed for the rational evaluation of com peting automatic analog patching systems. The design procedure described in this paper facilitates selection of the patching system best suited for a partic ular computer and a particular problem class. Sufficient information is abstracted from a typical problem set to determine the number of relays required for (and thus to assign a cost figure to) each possible patching system without requiring the actual design of each system. Nom inally, the best system is that with the lowest cost figure. It is recognized, however, that there are many subjective decisions (e.g., captive vs. free pots) involved in the de sign process that are not quantified in this overall cost figure. This problem is met in part by providing inter mediate information relating to the optimal module size, combinations of proposed systems, etc. to help estab lish some of the sensitivity properties of the optimal system. The procedure is illustrated by applying it to a particu lar case and evaluating a number of alternative switching systems.

2008 ◽  
Vol 132 (3) ◽  
pp. 490-499 ◽  
Author(s):  
Stephen A. Geller ◽  
Deepti Dhall ◽  
Randa Alsabeh

Abstract Context.—Immunohistochemistry has become an integral component of the practice of pathology. Newer antibodies allow for increasingly precise diagnoses for tumors that previously could not be easily identified. Recently, immunohistochemical evaluations have begun to allow pathologists to actively assist in determining prognosis and even in selecting therapies. Objective.—To summarize the usefulness of currently available immunostains for the study of liver and gastrointestinal system neoplasms and to make recommendations for panels of immunostains that can be particularly helpful. Data Sources.—Information has been collected from recent literature as well as from personal experience and practice. Conclusions.—Many immunostains are now available for the practicing pathologist that allow for increasing accuracy in diagnosis of liver and gastrointestinal tract neoplasms. Panels of immunostains can be used to differentiate between various tumors and also to identify site of origin in the case of a metastatic neoplasm. Immunostains that allow for prognostic determinations and for guidance in the selection of chemotherapeutic agents can also be used by pathologists to assist in the management of patients with malignant tumors affecting the liver and gastrointestinal tract.


Author(s):  
S W Kim ◽  
J S Park

An optimum design methodology is presented for point-to-point motion control servo systems in which d.c. permanent magnetic motors are used as the main actuators. Emphasis is focused on establishing a series of comprehensive decision-making practices in dealing with three major design subjects: determination of the velocity profile, optimization of the speed reduction ratio, and selection of the motor. Finally, a practical design example is discussed to illustrate how the suggested design methodology may be applied to actual design problems.


Author(s):  
Roberto Strada ◽  
Bruno Zappa ◽  
Hermes Giberti

“Flying machining” represents synchronization of an axis (slave) with a master axis in motion. One of the most important aspects of the design of “flying machining” operation is the choice of the proper law of motion of the slave axis. In literature, technical reports and papers can be found concerning this subject, but they deal with specific problems and the solutions or suggestions proposed are specific as well, suitable for those cases. In order to try to overcome this limitation, in this paper we analyze the subject of the flying machining operations from a wider point of view. We propose a unified design procedure with general validity, suitable for the choice of the slave axis’ law of motion for whatever “flying machining” operation. Furthermore methodologies for the selection of the drive system will be proposed. The procedure is described applying it on a cross sealing operation, typical of wrapping machine.


Author(s):  
Tawanda Mushiri ◽  
Panashe Adrian Mombeyarara ◽  
Thanks Marisa

The use of a wheelchair for normal routines or rehabilitation has various physiological and psychological implications. The use of contact assistive robots in developing countries is limited mainly due to their expensive nature. The benefits of exoskeleton use include health improvement, increased self-dependency, and self-sustenance. The chapter offers a solution through the design of a cheap contact assistive robot for the disabled. The design procedure includes the integration of acquired knowledge on gait training and existing exoskeletons acquired from intense research, visits to rehabilitation centers, and use of computer-aided software for design and simulations. A fully functioning scaled prototype was made that demonstrated the operating principle of the actual design. The design provides a successful baseline for further development of exoskeletons suitable and cheaper for developing countries with an initial estimated total material cost of USD$9000.


2020 ◽  
pp. 4395-4405
Author(s):  
Michael Doherty ◽  
Peter C. Lanyon

Disease markers are pathological or physiological characteristics of an individual that assist in determining the diagnosis, the current activity of disease, or the expected prognosis of the condition in that individual. Some markers relate to just one of these elements; others may relate to two, or occasionally all three. Clinical markers are derived from enquiry and examination of the patient. For many common rheumatic disorders, clinical assessment alone gives sufficient information for patient diagnosis and management. In some situations, however, particularly with inflammatory, metabolic, or multisystem disease, a search for additional investigational markers may be warranted. It is important to emphasize that the requirement for and selection of investigations, as well as their subsequent interpretation, is principally determined by the clinical assessment. Investigations are an adjunct, never a substitute, for competent clinical assessment. There is no place for a battery of screening tests.


2017 ◽  
Vol 37 (2) ◽  
pp. 500-531 ◽  
Author(s):  
Abdulrahman Abumurad ◽  
Kyusun Choi

Author(s):  
Young Hoon Lee

This article presents an extensive discussion of stochastic frontier “effects” models, which analyze factors influencing efficiency. The recent literature on team sports efficiency is also addressed. It offers an overview of the stochastic frontier model and equations for general models. It then compares various models that may be useful in analyses of determinants of efficiency and the effects models. The methodologies for inference within team efficiency estimation are explained. Additionally, a more detailed discussion of frontier models with time-varying efficiency is shown. The confidence interval from the percentile bootstrap should be precise enough for panel data with sufficiently large time-series observations because a bias problem is less likely. The discussion of the selection of input variables revealed that team playing talents can be decomposed into positional playing talents that have different roles in the process of producing output (producing wins).


2019 ◽  
Vol 9 (19) ◽  
pp. 4091
Author(s):  
Dong ◽  
Chen ◽  
Wang ◽  
Shi ◽  
Jiang ◽  
...  

Optical scatterometry is known as a powerful tool for nanostructure reconstruction due to its advantages of being non-contact, non-destructive, low cost, and easy to integrate. As a typical model-based method, it usually makes use of abundant measured data for structural profile reconstruction, on the other hand, too much redundant information significantly degrades the efficiency in profile reconstruction. We propose a method based on dependence analysis to identify and then eliminate the measurement configurations with redundant information. Our experiments demonstrated the capability of the proposed method in an optimized selection of a subset of measurement wavelengths that contained sufficient information for profile reconstruction and strikingly improved the profile reconstruction efficiency without sacrificing accuracy, compared with the primitive approach, by making use of the whole spectrum.


2020 ◽  
pp. 107754632092393
Author(s):  
Yongqiang Gong ◽  
Liang Cao ◽  
Simon Laflamme ◽  
James Ricles ◽  
Spencer Quiel ◽  
...  

The motion of cladding systems can be leveraged to mitigate natural and man-made hazards. The literature counts various examples of connections enhanced with passive energy dissipation capabilities at connections. However, because such devices are passive, their mitigation performance is typically limited to specific excitations. The authors have recently proposed a novel variable friction cladding connection capable of mitigating hazards semi-actively. The variable friction cladding connection is engineered to transfer lateral forces from the cladding element to the structural system. Its variation in friction force is generated by a toggle-actuated variable normal force applied onto sliding friction plates. In this study, a multiobjective motion-based design methodology integrating results from the previous work is proposed to leverage the variable friction cladding connection for nonsimultaneous wind, seismic, and blast hazard mitigation. The procedure starts with the quantification of each hazard and performance objectives. It is followed by the selection of dynamic parameters enabling prescribed performance under wind and seismic loads, after which an impact rubber bumper is designed to satisfy motion requirements under blast. Last, the peak building responses are computed and iterations conducted on the design parameters on the satisfaction of the motion objectives. The motion-based design procedure is verified through numerical simulations on two example buildings subjected to the three nonsimultaneous hazards. The performance of the variable friction cladding connection is also assessed and compared against different control cases. Results show that the motion-based design procedure yields a conservative design approach in meeting all of the motion requirements and that the variable friction cladding connection performs significantly well at mitigating vibrations.


Leonardo ◽  
2018 ◽  
Vol 51 (2) ◽  
pp. 181-182
Author(s):  
Michel van Dartel ◽  
Anne Nigten

This paper argues that a first step in finding a sustainable solution for the pressing global issue of ‘waste’, is to consider waste a value attribution rather than a material condition. Doing so means a shift in focus from finding more efficient ways to ‘clean up the mess’ to changing the way in which value is attributed to things. The paper looks at a selection of recent literature on value systems to identify useful concepts and theory for a value-based solution to waste and proposes to probe such potential solutions through art and design.


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