Simple Endoscopic Application of Laryngeal Keel Stent

2021 ◽  
pp. 019459982110021
Author(s):  
Ahmed Hassan Sweed ◽  
Mohamed Mobashir ◽  
Abd Elraof Said Mohamed ◽  
Ahmed Ibrahim Elsayed ◽  
Ashraf Elmalt ◽  
...  
Keyword(s):  
Anterior Commissure ◽  
Skin Surface ◽  
The Other ◽  
Patent Airway ◽  
Voice Outcome ◽  
Endoscopic Application ◽  
Special Instrumentation

This study describes a simple extraendolaryngeal technique to apply laryngeal keel in dealing with anterior commissure web/fibrosis. Standard extraendolaryngeal punctures were applied via 20-gauge needles, 30° from the skin surface, in midline through the cricothyroid and thyrohyoid membranes. These needles were used as a conduit for the passage of 2/0 Prolene threads, which were retrieved through the laryngoscope by crocodile forceps. Both laryngoscopic ends of the Prolene threads were passed through a fabricated silastic sheet (keel stent) via a 22-gauge free needle, and these ends were tied to have a secure internal knot. Steady traction was applied on the other 2 external threads until there was appropriate application of this keel stent within the vicinity of anterior commissure. Finally, these external ends were tied to have a secure external knot. A keel stent could be applied without the need for special instrumentation and with reasonable outcomes (proper healing of anterior commissure, satisfied voice outcome, and patent airway).

Prognostic Factors in Early Glottic Carcinoma Implications for Treatment

2005 ◽  
Vol 91 (2) ◽  
pp. 182-187 ◽  
Author(s):  
Demiral Ayse Nur ◽  
Cetinayak Oguz ◽  
Erdag Taner Kemal ◽  
Eyiler Ferhat ◽  
Sarıoglu Sülen ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Treatment Time ◽  
Salvage Surgery ◽  
Anterior Commissure ◽  
The Other ◽  
Second Primary ◽  
Partial Laryngectomy ◽  
Glottic Carcinoma ◽  
T Classification ◽  
Early Glottic Carcinoma

Aim In this study we aimed to determine the prognostic factors affecting local control (LC) in limited glottic carcinoma treated with definitive radiotherapy (RT). Material and methods Between June 1991 and December 2001, 114 patients with early squamous-cell carcinoma of the glottis were treated with definitive RT at our institution. Only four (3.5%) patients were women. The median age was 60 (27-79). Fifteen percent, 72% and 13% of the patients had Tis, T1 and T2 tumors, respectively. Forty-three (37.7%) patients had anterior commissure invasion. Prior to RT 35 (31%) patients had undergone vocal cord stripping and two (2%) cordectomy. A median dose of 66 Gy (50-70.2) was given over a median period of 46 days (20-60). Univariate and multivariate analyses were performed for LC. The prognostic parameters analyzed for LC were T classification, anterior commissure involvement, total RT dose, and overall treatment time. Results Five-year local and regional control rates were 84.2% and 97.7%. RTOG grade 3-4 late side effects were observed only in one (0.9%) patient. In 15 patients with local failure, salvage treatment consisted of partial laryngectomy in eight patients and total laryngectomy in five. One of the remaining two patients was medically inoperable, and the other refused salvage surgery. In one of the three patients with regional failure, salvage surgery was applied and the other two were given palliative chemotherapy because of unresectable disease. Following salvage treatments, the ultimate five-year LC rate was 96.9% and the five-year larynx preservation rate was 91.1%. Second primary cancer was diagnosed in 17 (14.9%) patients. Only one patient developed distant metastases and two patients died of laryngeal cancer. While T2 disease and anterior commissure involvement were found to be unfavorable prognostic factors significantly influencing LC in univariate analyses, only T2 disease remained independent in multivariate analysis. Conclusion In patients with early glottic carcinoma, T classification proved to be the only independent prognostic factor affecting LC after primary radiotherapy according to the results of this study.

Effect of water temperature on cooling efficiency during hyperthermia in humans

2003 ◽  
Vol 94 (4) ◽  
pp. 1317-1323 ◽  
Author(s):  
C. I. Proulx ◽  
M. B. Ducharme ◽  
G. P. Kenny
Keyword(s):  
Oxygen Consumption ◽  
Water Temperature ◽  
Cooling Rate ◽  
Water Immersion ◽  
Maximal Oxygen Consumption ◽  
Skin Surface ◽  
The Other ◽  
Cooling Efficiency ◽  
Rate Of Cooling ◽  
Exercise Induced

We evaluated the cooling rate of hyperthermic subjects, as measured by rectal temperature (Tre), during immersion in a range of water temperatures. On 4 separate days, seven subjects (4 men, 3 women) exercised at 65% maximal oxygen consumption at an ambient temperature of 39°C until Treincreased to 40°C (45.4 ± 4.1 min). After exercise, the subjects were immersed in a circulated water bath controlled at 2, 8, 14, or 20°C until Trereturned to 37.5°C. No difference in cooling rate was observed between the immersions at 8, 14, and 20°C despite the differences in the skin surface-to-water temperature gradient, possibly because of the presence of shivering at 8 and 14°C. Compared with the other conditions, however, the rate of cooling (0.35 ± 0.14°C/min) was significantly greater during the 2°C water immersion, in which shivering was seldom observed. This rate was almost twice as much as the other conditions ( P < 0.05). Our results suggest that 2°C water is the most effective immersion treatment for exercise-induced hyperthermia.

scholarly journals Levels of Firmicutes, Actinobacteria Phyla and Lactobacillaceae Family on the Skin Surface of Broiler Chickens (Ross 308) Depending on the Nutritional Supplement and the Housing Conditions

Agriculture ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 287
Author(s):  
Paulina Cholewińska ◽  
Marta Michalak ◽  
Konrad Wojnarowski ◽  
Szymon Skowera ◽  
Jakub Smoliński ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Rapeseed Meal ◽  
Skin Surface ◽  
Nutritional Supplement ◽  
The Other ◽  
Feed Additive ◽  
Pcr Analysis ◽  
Housing Conditions ◽  
Variable Level ◽  
Firmicutes Phylum

The microbiome of animals, both in the digestive tract and in the skin, plays an important role in protecting the host. The skin is one of the largest surface organs for animals; therefore, the destabilization of the microbiota on its surface can increase the risk of diseases that may adversely affect animals’ health and production rates, including poultry. The aim of this study was to evaluate the effect of nutritional supplementation in the form of fermented rapeseed meal and housing conditions on the level of selected bacteria phyla (Firmicutes, Actinobacteria, and family Lactobacillaceae). The study was performed on 30 specimens of broiler chickens (Ross 308), individually kept in metabolic cages for 36 days. They were divided into 5 groups depending on the feed received. On day 36, skin swabs were individually collected. Temperature and humidity were measured in the room. The temperature was measured every 2 days (18 measurements × 6 points). The results of Real-Time PCR analysis have shown a significant effect of the feed additive on the level of Firmicutes phylum on the skin. On the other hand, a variable level of the tested bacteria was shown depending on the location of the cages. The Firmicutes phylum and Lactobacillaceae family achieved the highest level in the top-window zone. However, in the case of the Actinobacteria phylum, the highest level was found at the top-door and middle-door zones. The obtained results suggest that the conditions in which animals live may affect the microbiota of their skin.

scholarly journals The microbiota of the surface, dermis and subcutaneous tissue of dog skin

2020 ◽  
Author(s):  
Rocío García-Fonticoba ◽  
Lluis Ferrer ◽  
Olga Francino ◽  
Anna Cusco
Keyword(s):  
Subcutaneous Tissue ◽  
Dna Amplification ◽  
Skin Surface ◽  
Molecular Techniques ◽  
The Other ◽  
Rrna Gene ◽  
Culture Methods ◽  
Bacterial Dna ◽  
Microbiological Culture ◽  
Two Samples

Abstract Background. Studies using highly sensitive molecular techniques have detected bacterial communities below the human epidermis. Depending on their abundance and composition, this finding could be clinically relevant. The aim of this study was to determine if bacteria can be detected in the dermis and subcutaneous tissue of dogs without cutaneous disease using two different approaches: traditional cultures and DNA sequencing of the V4 region of bacterial 16S rRNA gene using next-generation sequencing (NGS).Results. Seven healthy dogs were included in the study, and two sets of samples were collected from each subject. Sample sets were composed of a 6-mm abdominal skin biopsy, including epidermis, dermis, and subcutis, a skin surface swab, and an environmental blank sample for contamination control. One set of samples from each dog was submitted for bacterial culture and the other one for bacterial DNA amplification and sequencing. Five different bacterial genera (Staphylococcus, Bacillus, Corynebacterium, Streptococcus, and Enterococcus) were isolated in five out of the seven skin surface swab samples with aerobic microbiological culture methods, while no growth was obtained from the other two samples. Although some DNA could be amplified from epidermal, dermal, and subcutaneous tissue samples, the results of the NGS were similar to those of the blanks.Conclusion. When investigated with aerobic microbiological culture methods, the dermis and subcutaneous tissue of dogs are sterile. NGS techniques lead to the detection of some bacterial DNA, similar to the signal detected in blanks, which does not support the presence of a microbiota in dermis or subcutaneous tissue.

scholarly journals Effect of time in lairage on caecal and carcass salmonella contamination of slaughter pigs

1987 ◽  
Vol 98 (3) ◽  
pp. 323-330 ◽  
Author(s):  
I. R. Morgan ◽  
F. L. Krautil ◽  
J. A. Craven
Keyword(s):  
Longitudinal Study ◽  
Skin Surface ◽  
The Other ◽  
Isolation Rate ◽  
Slaughter Pigs ◽  
Salmonella Serotypes ◽  
Pig Carcasses

SUMMARYA longitudinal study of the effect of time spent in lairage on salmonellas in the caecum and on the skin surface of 450 slaughter pigs from a single producer was conducted. Pigs were tested in 6 groups at 2 abattoirs, with one-third of a group being slaughtered after 18 h, one-third after 42 h and one-third after 66 h spent in lairage. The salmonella isolation rate from caeca and carcass surfaces increased significantly with increasing time spent in lairage. Salmonellas were isolated from the caeca of 18·5% of pigs held less than 24 h in lairage, 24·1% of pigs held a further 24 h and 47·7% of pigs held for 66 h in lairage before slaughter. The salmonella isolation rates from carcasses were 9·3%, 12·8% and 27·3% for the same groups. Thirteen salmonella serotypes were isolated from the caecal contents and carcasses over the 6 weeks of the trial. One abattoir had a higher salmonella isolation rate from pigs than the other and this was probably related to lairage management. It appeared that lairage is an important factor in the manipulation of the salmonella contamination of pig carcasses.

Bacteriology of Electrically Stimulated and Unstimulated Rabbit, Pork, Lamb and Beef Carcasses

1980 ◽  
Vol 43 (9) ◽  
pp. 686-693 ◽  
Author(s):  
B. MRIGADAT ◽  
G. C. SMITH ◽  
T. R. DUTSON ◽  
L. C. HALL ◽  
M. O. HANNA ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Ground Beef ◽  
Skin Surface ◽  
The Other ◽  
Plate Count ◽  
Supraspinatus Muscle ◽  
Beef Carcasses ◽  
Aerobic Plate Count ◽  
Stimulation Of

Electrical stimulation of rabbit muscles caused a reduction in count of Pseudomonas putrefaciens and of a Lactobacillus sp. when inoculated muscles were held for 45 min after electrical stimulation. Little if any change in count was detected on rabbit muscles immediately after electrical stimulation and after 20 min of storage. Electrical stimulation (ES) of pork carcasses did not affect the aerobic plate count (APC) of the skin surface. APC of cutaneous trunci from electrically stimulated sides of beef and lamb carcasses were similar to those of muscles from unstimulated sides or carcasses. APC of ground beef and blade steaks fabricated pre-rigor from electrically stimulated sides were often numerically lower after 3 days of storage than those of corresponding samples from unstimulated sides. Differences in APC between conventional and ES samples of ground beef prepared from vacuum packaged top round were significant (P &lt; 0.05) after 6 days of storage. However, none of the other differences in count were statistically significant (P &lt; 0.05). Electrical stimulation did not cause any consistent substantial changes in microbial types of ground beef, blade steaks, T-bone steaks or rib steaks. When minced, aseptically excised supraspinatus muscle was inoculated with either P. putrefaciens or a Lactobacillus sp., counts of these species in tissues from electrically stimulated beef often were significantly lower than those of corresponding unstimulated samples.

scholarly journals Infiltrating basal cell carcinoma: a stellate peri-tumor dermatoscopy pattern as a clue to diagnosis

2015 ◽  
pp. 21-26
Author(s):  
John H. Pyne ◽  
Paul Fishburn ◽  
Anthony Dicker ◽  
Michael David
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Surface ◽  
Kappa Coefficient ◽  
The Other ◽  
Histopathologic Examination ◽  
Tumor Depth ◽  
Tumor Mass ◽  
Shaped Pattern

Background: Infiltrating basal cell carcinoma (BCC) has associated features that may be readily identified using dermatoscopy.  Objective: Investigate a stellate dermatoscopy pattern extending from the peripheral margin of infiltrating BCC. Methods: A total of 741 consecutive cases of BCC were assessed retrospectively using non-polarized dermatoscopy. Following histopathologic examination, cases were categorized into six different BCC subtypes. Infiltrating cases numbered 107. This stellate feature was defined as a geometric star shaped pattern extending outwards from the circumferential peripheral edge of the tumor, and identified by white lines, vessels or uneven skin surface morphology. The percentages of infiltrating subtype within the tumor mass and tumor depth were compared, with and without the stellate pattern. Results: Infiltrating BCC displayed the stellate pattern more than other BCC subtypes. Concordance between the two observers was almost perfect for white lines: Kappa coefficient of 0.87 (95% CI: 0.0.79-0.95) P<0.01 and substantial for vessels: Kappa coefficient of 0.71 95% CI: 0.59-0.84) P<0.01. Folds were only recorded in infiltrating cases (n=3). Compared to other BCC subtypes the stellate pattern had a sensitivity of 31.7% and specificity of 94.1%. A higher mean fraction of the tumor mass containing infiltrating subtype was found when comparing stellate pattern observed to stellate pattern not observed (P<0.01). No statistically significant association was found between the tumor depth with and without the stellate pattern. Conclusion: This study found a higher incidence of the stellate pattern within infiltrating BCC compared to the other BCC subtypes. As the percentage of the infiltrating subtype within the tumors increased the incidence of the stellate pattern also increased.

scholarly journals The microbiota of the surface, dermis and subcutaneous tissue of dog skin

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Rocío García-Fonticoba ◽  
Lluís Ferrer ◽  
Olga Francino ◽  
Anna Cuscó
Keyword(s):  
Subcutaneous Tissue ◽  
Dna Amplification ◽  
Skin Surface ◽  
Molecular Techniques ◽  
The Other ◽  
Rrna Gene ◽  
Culture Methods ◽  
Bacterial Dna ◽  
Microbiological Culture ◽  
Two Samples

Abstract Background Studies using highly sensitive molecular techniques have detected bacterial communities below the human epidermis. Depending on their abundance and composition, this finding could be clinically relevant. The aim of this study was to determine if bacteria can be detected in the dermis and subcutaneous tissue of dogs without cutaneous disease using two different approaches: traditional cultures and DNA sequencing of the V4 region of bacterial 16S rRNA gene using next-generation sequencing (NGS). Results Seven healthy dogs were included in the study, and two sets of samples were collected from each subject. Sample sets were composed of a 6-mm abdominal skin biopsy, including epidermis, dermis, and subcutis, a skin surface swab, and an environmental blank sample for contamination control. One set of samples from each dog was submitted for bacterial culture and the other one for bacterial DNA amplification and sequencing. Five different bacterial genera (Staphylococcus, Bacillus, Corynebacterium, Streptococcus, and Enterococcus) were isolated in five out of the seven skin surface swab samples with aerobic microbiological culture methods, while no growth was obtained from the other two samples. Although some DNA could be amplified from epidermal, dermal, and subcutaneous tissue samples, the results of the NGS were similar to those of the blanks. Conclusion When investigated with aerobic microbiological culture methods, the dermis and subcutaneous tissue of dogs are sterile. NGS techniques lead to the detection of some bacterial DNA, similar to the signal detected in blanks, which does not support the presence of a microbiota in dermis or subcutaneous tissue.

scholarly journals Development of a Multi-DOF Electromyography Prosthetic System Using the Adaptive Joint Mechanism

2006 ◽  
Vol 3 (2) ◽  
pp. 101-111 ◽  
Author(s):  
A. Hernandez Arieta ◽  
R. Katoh ◽  
H. Yokoi ◽  
Y. Wenwei
Keyword(s):  
Mechanical Design ◽  
Skin Surface ◽  
The Other ◽  
Joint Torque ◽  
Prosthetic Hand ◽  
Simple Pattern ◽  
Information Process ◽  
Nonlinear Properties ◽  
Emg Signal ◽  
Joint Mechanism

This paper describes an electrically powered prosthetic system controlled by electromyography (EMG) signal detected from the skin surface of the human body. The research of electrically powered prosthetic systems is divided into two main subjects. One is the design of the joint mechanism. We propose the use of an adaptive joint mechanism based on the tendon-driven architecture. This mechanism includes mechanical torque–velocity converters and a mechanism to assist the proximal joint torque by distal actuators. The other subject is the recognition of the EMG signal. For the discrimination of many patterns and nonlinear properties of the EMG signal, we propose a controller based on a simple pattern recognition information process. The system also drives 12 servomotors to move the adaptive joint mechanism. In this paper, we show the proposed system and describe the mechanical design of the prosthetic hand. The experimental results show that the electrically powered devices can be controlled using the proposed method.

scholarly journals The microbiota of the surface, dermis and subcutaneous tissue of dog skin

2020 ◽  
Author(s):  
Rocío García-Fonticoba ◽  
Lluis Ferrer ◽  
Olga Francino ◽  
Anna Cusco
Keyword(s):  
Subcutaneous Tissue ◽  
Skin Surface ◽  
Molecular Techniques ◽  
The Other ◽  
Rrna Gene ◽  
Culture Methods ◽  
Bacterial Dna ◽  
Microbiological Culture ◽  
Two Samples ◽  
Healthy Dogs

Abstract Background. Studies using highly sensitive molecular techniques have detected bacterial communities below the human epidermis. Depending on their abundance and composition, this finding could be clinically relevant. This possibility, however, has not been investigated in the dog so far. The aim of this study was to determine if bacteria can be detected in the dermis and subcutaneous tissue of healthy dogs using two different approaches: traditional cultures and DNA sequencing of the V4 region of bacterial 16S rRNA gene using next-generation sequencing (NGS). Results. Seven healthy dogs were included in the study, and two sets of samples were collected from each subject. Sample sets were composed of a 6-mm abdominal skin biopsy, including epidermis, dermis, and subcutis, a skin surface swab, and an environmental blank sample for contamination control. One set of samples from each dog was submitted for bacterial culture and the other one for bacterial DNA amplification and sequencing. Five different bacterial genera (Staphylococcus, Bacillus, Corynebacterium, Streptococcus, and Enterococcus) were isolated in five out of the seven skin surface swab samples with aerobic microbiological culture methods, while no growth was obtained from the other two samples. Although some DNA could be amplified from epidermal, dermal, and subcutaneous tissue samples, the results of the NGS were similar to those of the blanks. Conclusion. When investigated with aerobic microbiological culture methods, the dermis and subcutaneous tissue of dogs are sterile. NGS techniques lead to the detection of some bacterial DNA, similar to the signal detected in blanks, which does not support the presence of a microbiota in dermis or subcutaneous tissue.

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