Factors Predicting the Outcome of Intraarterial Thrombolysis in Peripheral Arterial and Graft Occlusions

Purpose: To determine the association between successful intraarterial thrombolysis and the following factors: sex, age, symptoms, duration of symptoms, length of occlusion, conduit type, runoff, and catheter localization. Material and Methods: Forty-six patients with acute or subacute occlusions of peripheral native arteries and grafts were treated with continuous intraarterial infusion of streptokinase or urokinase. A univariate chi-square test and logistic regression analysis were used. Results: Successful lysis was achieved in 27 of 46 patients (59%). The logistic regression analysis revealed a significant association between successful thrombolysis and good runoff (p<0.01). A catheter position above the occlusion resulted in lysis in only one of 11 patients. The variables rest pain and claudication were slightly significant (p=0.07). None of the other variables were significant, but a trend toward a separate effect of duration of occlusion was found. Conclusion: Good runoff and intrathrombotic infusion are virtual necessities in obtaining a positive immediate outcome in peripheral arterial and graft occlusions. In our study, other factors were less important.

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Factors affecting the occurrence of proximal endoleak after endovascular abdominal aortic repair for abdominal aneurysms

Journal of International Medical Research ◽

10.1177/0300060520971515 ◽

2020 ◽

Vol 48 (11) ◽

pp. 030006052097151

Author(s):

Daniela Mazzaccaro ◽

Girolomina Mazzeo ◽

Gianmarco Zuccon ◽

Alfredo Modafferi ◽

Giovanni Malacrida ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Aortic Aneurysms ◽

P Value ◽

Chi Square ◽

Factors Affecting ◽

Axial Diameter ◽

Abdominal Aortic ◽

Type Ia

Objective This retrospective study was performed to assess the clinical and radiological variables associated with proximal type IA endoleak (EL) in patients treated with elective endovascular repair for abdominal aortic aneurysms. Methods The chi-square test, t-test, and logistic regression analysis were performed as appropriate. A P value of <0.05 was considered statistically significant. Results The data of 79 patients were analyzed. No mortality occurred. During follow-up (median, 28.5 months; interquartile range, 12.8–43.0 months), 10 patients developed type IA EL. In the logistic regression analysis, undersizing of the endograft diameter by <10% significantly affected the occurrence of type IA EL. When the diameter was used for measurements, less oversizing was significantly associated with a higher risk of type IA EL. When the area was used for measurements, oversizing of >20% significantly affected the occurrence of type IA EL. Conclusion When sizing endografts, a discrepancy was noted between the measurements of the diameter and area of the proximal neck. The area might represent a more accurate measurement than the axial diameter to optimize the proximal sealing and lower the risk of developing type IA EL.

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Preseptal and Orbital Cellulitis: Thirteen Years of Experience and a Novel Scoring System (SNIPPED Score) for Differentiation

10.21203/rs.3.rs-792383/v1 ◽

2021 ◽

Author(s):

Rumeysa Yalçınkaya ◽

Gönül Tanır ◽

Suna Özdem ◽

Meltem Polat ◽

Zeynep Savaş Şen ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Scoring System ◽

Orbital Cellulitis ◽

Upper Respiratory Tract ◽

Duration Of Symptoms ◽

Preseptal Cellulitis ◽

System A ◽

Beta Coefficient

Abstract We aimed to evaluate clinical and laboratory characteristics of children with preseptal cellulitis (PC) or orbital cellulitis (OC) and to determine whether easily-accessible parameters could be used to predict OC. The data of children diagnosed with PC or OC between January 2008 and December 2020 were evaluated. Patients aged between 1 month and 18 years who were treated with intravenous antibiotics were included. Logistic regression analysis was performed to identify possible parameters in differentiating between PC and OC. A beta coefficient-based method was used to derive the scoring system. A total of 375 patients [202 (53.9%) boys], of whom 35 (9.3%) had OC, were evaluated. Median age was 44 (min-max: 1-192) months. Compared to those with PC, patients with OC were older (p = 0.001), had fever and upper respiratory tract infection (URTI) symptoms more frequently, and demonstrated prolonged symptom and hospitalization times (p˂0.001 for all). Significant differences between groups were observed for numerous parameters; however, logistic regression analysis revealed only five parameters independently associated with OC. The SNIPPED score variables and weights were as follows: sinusitis (2 points), neutrophil-to-lymphocyte ratio > 6.78 (3 points), platelet count > 420.5 x103/mm3 (2 points), proptosis (4 points) and duration of symptoms ≥ 4 days (4 points). A cut-off of ≥ 7 points for OC diagnosis was found to have 91.4% sensitivity, 96.2% specificity, 71.1% PPV, 99.1% NPV and 95.7% accuracy. Conclusion: In addition to showing previously known properties of OC versus PC, our study demonstrated that easily-accessible parameters could be used for the identification of OC.

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Methods of Radiology Reports Generation and Patterns of Associated Musculoskeletal Symptoms: A Cross-Sectional Multi-Center Study

10.21203/rs.3.rs-16289/v1 ◽

2020 ◽

Author(s):

Omran Al Dandan ◽

Ali Hassan ◽

Hind Alsaif ◽

Malak Al Shammari ◽

Danya Gari ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Online Survey ◽

Musculoskeletal Symptoms ◽

Multivariable Logistic Regression Analysis ◽

Chi Square ◽

Cross Sectional ◽

Radiology Reports ◽

Multi Center Study

Abstract Objectives This study aimed to investigate the association between the methods used to generate radiology reports and the prevalence of musculoskeletal symptoms among radiologists. Additionally, we investigated the factors associated with the use of such methods. Methods An online survey was sent to radiologists practicing in hospitals in the Eastern Province of Saudi Arabia. The survey addressed demographic characteristics, work environment, and methods used to generate radiology reports and included an evaluation of musculoskeletal symptoms using the Nordic Musculoskeletal Questionnaire. Results were analyzed descriptively using the Chi-square test and logistic regression analysis. Results The survey was completed by 198 radiologists (111 men and 87 women), including residents (40.9%), specialists (27.3%), and consultants (31.8%). Most participants (71.2%) were aged below 40 years. In total, 140 (70.7%) participants had experienced musculoskeletal symptoms in the week preceding the survey. The most popular method used to generate radiology reports was typing using a keyboard, with 64.1% of participants using this method, followed by a handheld dictation device (49.5%). Radiologists with limited years of practice more frequently generated reports via keyboard typing, particularly those with <1-year of experience (35.8%). A multivariable logistic regression analysis revealed that radiologists who used handheld dictation devices were at higher risk of developing musculoskeletal symptoms. Conclusions Musculoskeletal symptoms are common among radiologists. Radiologists who use handheld dictation devices were particularly likely to report experiencing musculoskeletal symptoms. These devices were less commonly used among radiologists with fewer years of experience.

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Genetic Polymorphism in MMP9 May Be Associated With Anterior Open Bite in Children

Brazilian Dental Journal ◽

10.1590/0103-6440201600992 ◽

2017 ◽

Vol 28 (3) ◽

pp. 277-280 ◽

Cited By ~ 1

Author(s):

Erika Calvano Küchler ◽

Driely Barreiros ◽

Raphaela Oliveira da Silva ◽

Júlia Guimarães Barcellos de Abreu ◽

Ellen Cardoso Teixeira ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Protective Factor ◽

Recessive Model ◽

Open Bite ◽

Anterior Open Bite ◽

Chi Square ◽

Genotype Frequencies ◽

Chi Square Test

Abstract Anterior open bite (AOB) has a multifactorial etiology caused by the interaction of sucking habits and genetic factors. The aim of this study was to evaluate the association between AOB and polymorphisms in genes that encode Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs). Four hundred and seventy-two children that presented at least one sucking habit were evaluated. Children were examined clinically for the presence of AOB. Genomic DNA was extracted from saliva. Genotyping of the selected polymorphisms in MMP2, MMP3, MMP9, TIMP1 and TIMP2 was carried out by real-time PCR using the TaqMan method. Allele and genotype frequencies were compared between the groups with and without AOB using the PLINK® software in a free and in a recessive model using a chi-square test. Logistic regression analysis was implemented (p≤0.05). Two hundred nineteen children had AOB while 253 did not. The polymorphism rs17576 in MMP9 was significantly associated with AOB (p=0.009). In a recessive model GG genotype was a protective factor for AOB (p=0.014; OR 4.6, 95%CI 1.3-16.2). In the logistic regression analysis, none of the genes was associated with AOB. In conclusion, the polymorphism rs17576 (glutamine for arginine substitution) in MMP9 was a protective factor for AOB.

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Lumbar spondylolisthesis is a risk factor for osteoporotic vertebral fractures: a case–control study

Journal of International Medical Research ◽

10.1177/0300060518776067 ◽

2018 ◽

Vol 46 (9) ◽

pp. 3605-3612

Author(s):

Peng Wang ◽

Feng Wang ◽

Yan-Long Gao ◽

Jia-qi Li ◽

Jing-tao Zhang ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Previous History ◽

Vertebral Compression Fractures ◽

Chi Square ◽

Compression Fractures ◽

Chi Square Test ◽

History Of ◽

Lumbar Spondylolisthesis

Objective This study aimed to identify the risk factors for vertebral compression fractures in patients with osteoporosis. Methods A total of 864 patients with osteoporosis were enrolled in a retrospective study from February 2010 to June 2016. Patients with diseases, such as pathological fractures, high-energy direct injury to the thoracic or lumbar vertebrae, and severe spinal deformity, were excluded. The patients were divided into two groups: those with vertebral compression fractures (288) and those with no vertebral compression fractures (576). Information on the patients’ age, sex, lumbar bone mineral density (BMD), trauma, body mass index, previous history of vertebral compression fractures, and spondylolisthesis was recorded. Logistic regression analysis and the chi-square test were applied for comparisons. Results Univariate logistic regression analysis and chi-square test results showed no significant differences in age, sex, body mass index, type 2 diabetes, previous history of vertebral fracture, and trivial trauma between the groups. Multivariate analysis showed significant associations between spondylolisthesis and BMD. Logistic regression analysis showed that spondylolisthesis and BMD were risk factors for vertebral compression fractures. Conclusions Lumbar spondylolisthesis is an independent risk factor for vertebral compression fractures in patients with osteoporosis. Therefore, patients with osteoporosis and lumbar spondylolisthesis require more attention.

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Age at First Conception and its Determinants of Ever-Married Women in Bangladesh

International Journal of Scientific Research and Management ◽

10.18535/ijsrm/v9i8.sh03 ◽

2021 ◽

Vol 9 (08) ◽

pp. 683-395

Author(s):

Mohammad Manjur Alam

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Binary Logistic Regression ◽

Married Women ◽

Binary Logistic Regression Analysis ◽

Demographic And Health Surveys ◽

Chi Square ◽

Reproductive Process ◽

Chi Square Tests

Age at first conception is an important part of the reproductive process that identifies the level of fecundability and indicative fertility during the early stages of marriage. This study explores the age at first conception and its determinants of ever-married women in Bangladesh by extracting the recent Bangladesh Demographic and Health Surveys (BDHS 2017) data. Descriptive statistics, ANOVA, chi-square tests, and binary logistic regression analysis were carried out to analyze data. Overall, the mean age at first conception of Bangladeshi women is 17.82 ± 3.29 years with significant variations by different socio-demographic, cultural, and behavioral factors. Bivariate analysis of chi-square tests shows that all the independent variables have a significant effect on age at first conception. The finding of the binary logistic regression analysis revealed that respondents' current age, age at first cohabitation, respondents' education, and partners' education are the most important determinants of age at first conception in Bangladesh. Moreover, secondary (OR= 0.743, 95% CI = 0.622- 0.886, P < 0.01) and higher educated women (OR= 0.838, 95% CI = 0.710- 0.989, P < 0.05) were respectively less likely to having first conception at age above 17.25 years, compared to no educated women. Thus, to increase the age at the first conception and reduce the level of fertility, it is necessary to increase the age at the first marriage of the respondents and the level of education for both partners.

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Cancer patients with ECOG-PS higher than 1: Who are those who benefit of palliative chemotherapy?

Journal of Clinical Oncology ◽

10.1200/jco.2013.31.15_suppl.9561 ◽

2013 ◽

Vol 31 (15_suppl) ◽

pp. 9561-9561

Author(s):

Rafael Caires-Lima ◽

Bruno Mendonça Protásio ◽

Inacelli Queiroz de Souza Caires ◽

Lucila Soares Da Silva Rocha ◽

Julia Andrade De Oliveira ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Palliative Chemotherapy ◽

Metastatic Cancer ◽

Rank Test ◽

Fisher Exact Test ◽

Chi Square ◽

Factors Associated ◽

Ecog Ps

9561 Background: Palliative chemotherapy (PC) is a treatment option in pts with metastatic cancer. Although pts with ECOG-PS > 1 are underrepresented in clinical trials, they are often treated with PC in daily practice. We aimed to identify factors associated with poorer survival and lack of benefit of PC in this subset of pts. Methods: We conducted a case-control retrospective analysis of 301 consecutive pts with solid tumors and ECOG-PS > 1 when initiated PC, selected from 2514 pts who died between Aug/2011 and Jul/2012 in a tertiary cancer care institution or its hospice. Cases were defined as those pts who survived < 90d after the first cycle of first line PC, and controls were those who had a longer survival. Frequencies were compared by chi-square test or Fisher exact test. Risks were estimated by odds ratios (OR) and logistic regression analysis. Overall survival (OS) was calculated by Kaplan-Meier method and curves was compared using log-rank test. Results: 142 cases/159 controls were included: median age 58/63 y.o. (p=0.09; t-test) and 49%/50% female (p=0.941; chi-square). Gastrointestinal and lung cancers were the most frequent primaries (31 and 17%, respectively). Factors associated with poorer OS were age > 60 y.o. (OR 1.7; 95%CI 1.0–2.6), ECOG-PS > 2 (1.9; 1.2–3.1), weight loss > 10% (1.8; 1.1-2.8), hemoglobin < 10 g/dL (2.6; 1.6-4.2), albumin < 3 g/dL (2.7; 1.5-5.1), serum creatinine (sCr) > 1 mg/dL (2.8; 1.6-5.0), C-reactive protein ≥ 5 mg/L (8.6; 1.0-72.9), altered mental status (4.2; 1.4-13.2) and in-hospital PC (3.2; 1.9-5.2). Cases were more likely to experience grade ≥ 3 toxicity (43 vs. 28%; p=0.005), die of toxicity (16 vs. 6%; p = 0.0007) and not be offered palliative care only (47 vs. 71%; p<0.0001). mOS was 204 and 34d among controls and cases, respectively (HR 0.177; 95%CI 0.015-0.033, p<0.0001). Median time to death was 39.5d (0-1103). Logistic regression analysis identified ECOG-PS > 2 (OR 2.3, p=0.044) and sCr > 1 mg/dL (OR 11.2, p=0.0002) as independent predictors of 3-mo fatality. Conclusions: ECOG-PS > 2 and elevated sCr were identified as independent predictors of poor OS in these pts. PC needs to be prescribed with caution in ECOG-PS > 1 pts, since it seems to offer no benefit in OS and could lead to abbreviation of life.

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Functional and clinical outcomes following surgical treatment in patients with cervical spondylotic myelopathy: a prospective study of 81 cases

Journal of Neurosurgery Spine ◽

10.3171/2010.10.spine091029 ◽

2011 ◽

Vol 14 (3) ◽

pp. 348-355 ◽

Cited By ~ 80

Author(s):

Julio C. Furlan ◽

Sukhvinder Kalsi-Ryan ◽

Ahilan Kailaya-Vasan ◽

Eric M. Massicotte ◽

Michael G. Fehlings

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Surgical Treatment ◽

Postoperative Complications ◽

Logistic Regression Analysis ◽

Functional Recovery ◽

Cervical Spondylotic Myelopathy ◽

Functional Outcomes ◽

Duration Of Symptoms ◽

Medical Comorbidities

Object Cervical spondylotic myelopathy (CSM) is the most common cause of spinal dysfunction in the elderly. Operative management is beneficial for most patients with moderate/severe myelopathy. This study examines the potential confounding effects of age, sex, duration of symptoms, and comorbidities on the functional outcomes and postoperative complications in patients who underwent cervical decompressive surgery. Methods We included consecutive patients who underwent surgery from December 2005 to October 2007. Functional outcomes were assessed using the Nurick grading system and the modified Japanese Orthopaedic Association and Berg Balance scales. Comorbidity indices included the Charlson Comorbidity Index and the number of ICD-9 codes. Results There were 57 men and 24 women with a mean age of 57 years (range 32–88 years). The mean duration of symptoms was 25.2 months (range 1–120 months). There was a significant functional recovery from baseline to 6 months after surgery (p < 0.01). Postoperative complications occurred in 18.5% of cases. Although the occurrence of complications was not significantly associated with sex (p = 0.188), number of ICD-9 codes (p = 0.113), duration of symptoms (p = 0.309), surgical approach (p = 0.248), or number of spine levels treated (p = 0.454), logistic regression analysis showed that patients who developed complications were significantly older than patients who had no complications (p = 0.018). Only older age (p < 0.002) and greater number of ICD-9 codes (p < 0.01) were significantly associated with poorer functional recovery after surgical treatment. However, none of the studied factors were significantly associated with clinically relevant functional recovery after surgical treatment for CSM (p > 0.05). Conclusions Our results indicate that surgery for CSM is associated with significant functional recovery, which appears to reach a plateau at 6 months after surgery. Age is a potential predictor of complications after decompressive surgery for CSM. Whereas older patients with a greater number of preexisting medical comorbidities had less favorable functional outcomes after surgery for CSM in the multivariate regression analysis, none of the studied factors were associated with clinically relevant functional recovery after surgery in the logistic regression analysis. Therefore, age-matched protocols based on preexisting medical comorbidities may reduce the risk for postoperative complications and improve functional outcomes after surgical treatment for CSM.

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Abstract P21: Racial Disparity in Participation Among Patients in an Urban Cardiac Rehabilitation Program

Circulation Cardiovascular Quality and Outcomes ◽

10.1161/circoutcomes.4.suppl_2.ap21 ◽

2011 ◽

Vol 4 (suppl_2) ◽

Author(s):

Maria Sobolev ◽

David Z Prince ◽

Ju Gao ◽

Cynthia Taub

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Cardiac Rehabilitation ◽

Logistic Regression Analysis ◽

Racial Disparity ◽

Medical Center ◽

Rehabilitation Program ◽

Care Physician ◽

P Value ◽

Chi Square

Background: Despite evidence of benefit on morbidity and mortality, cardiac rehabilitation (CR) remains underutilized. Studies have identified multiple reasons for lack of participation, but few have addressed racial disparities that may exist. Methods: A database of patients referred to CR between May 2001 and January 2011 was constructed. Data on gender, race, age, specialty of referring physician, co-payment, reason for referral, and attendance were collected. Racial groups were classified as Caucasian or minorities (African American, Hispanic, Asian, Pacific Islander, and multi-racial). Reasons for referral included acute MI, CAD, stable angina, CHF, and valvular heart disease. Data was analyzed using a Chi-square test to compare the initiation and non-initiation groups. A multivariate logistic regression estimated the odds ratio of variables predicting CR initiation. Results: Of the 822 patients referred to CR, 488 (59.4%) initiated CR and 334 (40.6%) did not. There was no difference in age (61.6 vs. 61.6, p = 0.987) or gender distribution (36.9% vs. 41.6% females, p = 0.161) between groups. Furthermore, need for co-payment (p = 0.091), reason for referral (p = 0.490), and whether the referring physician was a specialist or primary care physician (p = 0.740) did not affect attendance. Overall, minorities initiated CR less often than Caucasians (34.8% vs. 45.6%, p = 0.003). Based on the logistic regression analysis, Caucasians were 78% more likely to initiate CR (OR 1.78; 95% CI 1.13-2.80). Older age was a negative predictor of CR initiation, with each year of age decreasing likelihood of initiation by 2% (OR 0.98; 95% CI 0.96-1.00). Conclusions: Racial disparity exists amongst CR participants, with a clear under-representation of minorities in our urban medical center. Gender, physician referral patterns, and need for co-payment did not influence participation. Further investigation is required to determine why such disparity exists. Logistic regression analysis of factors predictive of CR initiation FACTORS ADJUSTED OR 95% CI P-VALUE Age 0.976 [0.956-0.995] 0.016 Gender 1.285 [0.836-1.977] 0.253 Caucasian Race 1.775 [1.126-2.797] 0.013 Co-payment 1.010 [0.987-1.033] 0.389 PCP/Specialist Referral 0.841 [0.495-1.428] 0.521

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A Study of Taiwanese Banks’ Home Loan Life Insurance Attached to Home Loans

10.47260/jafb/10611 ◽

2020 ◽

pp. 225-239

Author(s):

Pih-Shuw Chen ◽

Jia-Jan Lee ◽

Pei-Fen Ou

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Life Insurance ◽

Insurance Industry ◽

Chi Square ◽

Factors Influencing ◽

Chi Square Test ◽

Main Factors ◽

Housing Guarantee

The purpose of this study is to understand the main factors influencing the additional purchase of home loan life insurance at the time of home loan processing with Taiwan's banks. We used Taiwanese banks 417 customers who applied for housing guarantee loans from between 2014-2018. The chi-square test shows that gender and occupation significantly influence the purchase of home loan life insurance. The logistic regression analysis indicates that occupation significantly influences the purchase of home loan life insurance. This study may provide a basis for banking practitioners to develop future customers in the insurance industry.

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