scholarly journals A Novel Device to Measure the Optimal Position of Central Incisors in Anteroposterior Dimension Clinically: “P” Device

2021 ◽  
pp. 030157422110116
Author(s):  
Pavankumar R Singh ◽  
Anand S Ambekar ◽  
Suresh K Kangane

Facial esthetic has always been a concern for humans for ages. The anteroposterior (AP) position of central incisors plays a key role in building facial esthetic in a smiling profile view. There have been various cephalometric, profilometric, and photographic methods used in the past to assess and predict the AP position of maxillary incisors in their optimal esthetic position. Our new device will help to predict, assess, and measure the optimal AP position of maxillary central incisors clinically using the glabella as a landmark.

Endoscopy ◽  
2018 ◽  
Vol 51 (01) ◽  
pp. 85-92 ◽  
Author(s):  
Kelly van Keulen ◽  
Helmut Neumann ◽  
Jörn Schattenberg ◽  
Aura van Esch ◽  
Wietske Kievit ◽  
...  

Abstract Background The importance of high quality preprocedural bowel preparation is widely acknowledged, but suboptimal bowel cleansing still occurs in up to 20 % of all colonoscopy patients. The aim of this study was to evaluate the performance of a novel intraprocedural cleaning device for cleaning poorly prepared colons. Methods This multicenter feasibility study included patients aged 18 – 75 years who were referred for colonoscopy. Intraprocedural cleaning was performed in patients after a limited preprocedural bowel preparation regimen (2 days of dietary restrictions and 2 × 10 mg bisacodyl). The primary outcome was the proportion of adequately prepared patients (Boston Bowel Preparation scale [BBPS] ≥ 2 in each segment) before and after segmental washing with the new device. Secondary outcomes included: cecal intubation rate, procedure time, system usability, patient satisfaction, and safety. Results 47 patients (42.6 % male), with a median age of 61 years (interquartile range [IQR] 46 – 67 years), were included at three clinical sites. Cecal intubation was achieved in 46/47 patients (97.9 %). The cleaning device significantly improved the proportion of patients with adequate bowel cleansing (from 19.1 % to 97.9 %; P < 0.001) and median BBPS score (from 3.0 [IQR 0.0 – 5.0] to 9.0 [IQR 8.0 – 9.0]). Median cecal intubation time and total procedure time were 16.5 minutes (IQR 9.0−28.3) and 34.0 minutes (IQR 25.0 – 42.8), respectively. Physicians were satisfied with the ease of use of the device and it was well tolerated by patients. No severe adverse events occurred during the study period. Conclusions This feasibility study suggests that the intraprocedural cleaning device appears to be safe and effective in cleaning poorly prepared colons to an adequate level, allowing a thorough colorectal examination.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1985100
Author(s):  
Ziad Al Adas ◽  
George Haddad ◽  
Bhavin C Patel ◽  
Lalathaksha Kumbar ◽  
Baha Al-Abid ◽  
...  

Arteriovenous fistula failure represents a major cause of hospitalization and a significant economic burden for end-stage renal disease patients on hemodialysis. The Optiflow (Bioconnect Systems Inc., Ambler, PA) is a new device developed to improve arteriovenous fistula outcomes and decrease failure rates by reducing the risk of stenosis and improving maturation rates. This case report describes a 50-year-old male with hypertensive nephropathy on dialysis who had multiple arteriovenous fistula failures in the past. He was scheduled to undergo brachiocephalic fistula construction using the Optiflow device. After 8 months of use, the new fistula developed a peri-anastomotic venous stenosis, just distal to the Optiflow device. To our knowledge, this is the first time such a complication has been reported.


2012 ◽  
Vol 4 (3) ◽  
pp. 32 ◽  
Author(s):  
Marco Caruselli ◽  
Dario Galante ◽  
Anna Ficcadenti ◽  
Laura Carboni ◽  
Federica Franco ◽  
...  

Progress in medical and scientific research has increased the chances of survival for young patients with congenital diseases, children who, in the past, would not have had any chance of survival. Nowadays, congenital diseases can be treated with appropriate replacement therapies. These treatments can be difficult to administer in young patients because of the high frequency of administration (sometimes more than a dose per week), the use of intravenous infusion and the long-term or life-term requirement.


2020 ◽  
Vol 35 (1) ◽  
pp. 49-58 ◽  
Author(s):  
Yuxin Cheng ◽  
Jie Shen ◽  
Ling Yuan ◽  
Yan Yang ◽  
Xiaoyan Shen ◽  
...  

Here, we describe a novel microfilter device to capture circulating tumor cells in an efficient and low-cost manner. Then, we validated the safety and clinical utility of the novel microfilter device. We next performed mutation analysis from circulating tumor cells collected from lung cancer patients using this new device. Our results indicate that this microfilter system can be used to investigate the genome landscape of circulating tumor cells collected from lung cancer patients. Further, our results highlight a proof-of-concept demonstration indicating that circulating tumor cell can be used for mutation profiling during tumor evolution, therapy prediction, and monitoring, with immediate clinical applicability.


2021 ◽  
Author(s):  
Kevin N. Chiu ◽  
David Anderson ◽  
Mark D. Fuge

Abstract Computational design methods provide opportunities to discover novel and diverse designs that traditional optimization approaches cannot find or that use physical phenomena in ways that engineers have overlooked. However, existing methods require supervised objectives to search or optimize for explicit behaviors or functions — e.g., optimizing aerodynamic lift. In contrast, this paper unpacks what it means to discover interesting behaviors or functions we do not know about a priori using data from experiments or simulation in a fully unsupervised way. Doing so enables computers to invent or re-invent new or existing mechanical functions given only measurements of physical fields (e.g., pressure or electromagnetic fields) without directly specifying a set of objectives to optimize. This paper explores this approach via two related parts. First, we study clustering algorithms that can detect novel device families from simulation data. Specifically, we contribute a modification to the Hierarchical Density-Based Spatial Clustering of Applications with Noise algorithm via the use of the silhouette score to reduce excessively granular clusters. Second, we study multiple ways by which we preprocess simulation data to increase its discriminatory power in the context of clustering device behavior. This leads to an insight regarding the important role that a design’s representation has in compactly encoding its behavior. We test our contributions via the task of discovering designs that function as fluidic logic gates. We generate synthetic data that mimics fluidic devices and show that our proposed contributions better discover logic gates, as measured by adjusted Rand score. Specifically, combining our Resolution Selection preprocessing and principal component analysis resulted in the highest and tightest spread of adjusted Rand scores on our tested datasets. This opens up new avenues of research wherein computers can automatically explore different types of physics and then derive new device functions, behaviors, and structures without the need for human labels or guidance.


2013 ◽  
Vol 4 (4) ◽  
pp. 186-191
Author(s):  
Milly Farrell

Intentional dental modification has been practised across Africa for the past 10,000 years; three variations have been noted: filing, chipping and evulsion. Of these, dental filing is the most prolific. Restyling of the teeth for aesthetic socio-cultural reasons is a practice with both a wide-ranging geographical trend and a broad temporal scale. This article presents the assessment of one specimen held within the Odontological Collection at the Royal College of Surgeons (RCS) that displays significant reshaping: four modified maxillary incisors from one individual, reportedly from the Kasai region of the Democratic Republic of the Congo, which have been filed into pronounced points. Observations have been made on the impact of modifying human teeth ante-mortem, and the resultant reaction of the dental tissues to invasive reshaping.


Coatings ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 562
Author(s):  
Imyhamy M. Dharmadasa

Photovoltaic (PV) technology is rapidly entering the energy market, providing clean energy for sustainable development in society, reducing air pollution. In order to accelerate the use of PV solar energy, both an improvement in conversion efficiency and reduction in manufacturing cost should be carried out continuously in the future. This can be achieved by the use of advanced thin film materials produced by low-cost growth techniques in novel device architectures. This effort intends to provide the latest research results on thin film photovoltaic solar energy materials in one place. This Special Issue presents the growth and characterisation of several PV solar energy materials using low-cost techniques to utilise in new device structures after optimisation. This will therefore provide specialists in the field with useful references and new insights into the subject. It is hoped that this common platform will serve as a stepping-stone for further development of this highly important field.


2013 ◽  
Vol 7 (4) ◽  
Author(s):  
Ying Ying Wu ◽  
Ryan Lucking ◽  
Robert Oberreuter ◽  
Kenji Shimada

Distraction osteogenesis is a procedure to correct bone deformity by breaking the bone and slowly pulling the fragments apart to stimulate bone growth. General bone deformities are three-dimensional in nature, requiring correcting of bone angles in 3D space and also bone length. However, commercially available external fixators are either unable to simultaneously correct for both angular and length deformity or are bulky and require as many as six joints that are adjusted by patients. In this paper, we propose a novel concept of correcting a 3D bone deformity using only two active degrees of freedom (2DOF), or two patient controlled joints, by expressing the orientation deformity of the bone using the axis-angle representation and the length discrepancy as a translation in 3D space. This requires a new device design with two patient-controlled joints, a revolute joint and a prismatic joint, that can be placed in any orientation and position to allow multiple configurations of the device. This in turn allows it to correct for all typical 3D deformities. The aim of our project is to develop the 2DOF axial external fixator and an algorithm for a planner to find the optimal fixator configuration and the correction schedule for a given deformity. An algorithm for the placement of the two patient-controlled joints relative to the osteotomy site was developed. A set of test data extracted from a deformed sawbone was used to check the performance of the proposed computational method. The desired bone trajectory was defined as a straight line from initial to target position, and the optimal position of the revolute joint gives an error of only 0.8 mm. We conclude that the proposed 2DOF device and the computational planner can correct typical bone deformity and works well for the test case in simulation.


2021 ◽  
pp. 030157422110180
Author(s):  
Pavankumar R Singh ◽  
Anand S Ambekar ◽  
Suresh K Kangane

In orthodontic diagnosis and treatment planning, soft tissue profile assessment is of prime importance. Due to the emerging soft tissue paradigm, greater emphasis has been given to the clinical examination of soft tissue function and esthetics. Various cephalometric and photographic methods were introduced in the past to assess and measure profile angle and other facial angles. Our new device, that is, profilometer, helps to measure profile angle clinically.


2016 ◽  
Vol 5 (1) ◽  
pp. 72-75
Author(s):  
R Kranthi Kumar ◽  
BV Thimma Reddy ◽  
Neha Nayan

ABSTRACT Restoration of grossly mutilated primary maxillary incisors affected by early childhood caries has been a challenging task for the pediatric dentist due to the little amount of tooth structure available for bonding and behavioral problems of the children. A variety of treatment options ranging from extraction followed by prosthesis to the usage of intracanal pins and fiber posts have been reported in the past. The present case report depicts one such a case wherein biological restorations were used as post and core to restore the mutilated primary maxillary incisors in a 4-year-old child treated under general anesthesia. How to cite this article Kumar KR, Reddy BVT, Nayan N. Restoration of Mutilated Primary Maxillary Incisors using Biological Restorations under General Anesthesia. Int J Experiment Dent Sci 2016;5(1):72-75.


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