Leisure Functioning and Offender Rehabilitation

Author(s):  
Alison J. Link ◽  
D J Williams

This study examined the statistical relationship between offender rehabilitation and leisure functioning of Oregon prisoners ( N = 281) soon to reenter society. The strong positive correlation between leisure functioning and rehabilitation is an important finding of the study. Perception of freedom and intrinsic motivation in leisure, as independent variables, were significantly related to rehabilitation even when controlling for the influence of demographic and important forensic variables. This study provides initial empirical evidence for the importance of leisure in offender rehabilitation and successful offender reentry. The role of leisure education programming as a supportive offender rehabilitation strategy is also discussed.

Author(s):  
Alphonce Tavona Shiri

This chapter examines the concept of collective creativity in the work environment and in particular the manufacturing sector in Gweru, Zimbabwe. The chapter analyzes the role of a leader in fostering a work climate that cultivates collaborative efforts by followers in creating new ideas and for the sustainability of business operations. Literature relating to leadership role in enhancing sustainable and responsible collective creativity is reviewed. The chapter adopted a quantitative approach in which a survey questionnaire was pilot tested to assess the clarity of the questions on the questionnaire and test the internal consistency of the questions. A pilot test of the situational outlook questionnaire (SOQ) was conducted on 20 respondents in the manufacturing industry to assess the questions for clarity and internal consistency. The final survey questionnaire was distributed to 60 employees in the manufacturing sector in Gweru, Zimbabwe. The items on the questionnaire were rated on a 5 point Likert scale. Data was analysed using SPSS version 23. Data was analysed to determine the correlations between the independent variables and dependent variables. Transformational leadership constructs, namely idealised influence, intellectual stimulation, inspirational motivation and individualised consideration constituted leadership independent variables. Analysis of research data reveals that high performance is related to sustainable business practices such as the creation of environmentally friendly and affordable products. Unethical business practices are found to be negatively related to business performance and collective creativity. Analysis of the data revealed a positive correlation between individualised consideration construct of transformational leadership and ideal support (r=.527, p=.001) and a positive correlation between individualised consideration and openness (r=.343, p<.001), and a positive correlation between individualised consideration and involvement (r=.123, p<.001) This means that when a leader displays support through taking into consideration the individual needs of his or her followers, subordinates feel that the leader is encouraging them to participate in company activity and increase their perception of an involving climate. Acts of leadership support also stimulate subordinate views of an open forum where they can contribute to collective creativity within the organisation.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1074-1074
Author(s):  
S.B. Lee

AimTo develop and validate traumatic dream scales by further utilizing The Sang Bok Lee Neurocognitive Dream Orientation Scales (Lee, Sang Bok: 2010, European Psychiatry) assessing the narrative dream contents.Methods2450 dream were collected form 870 Korean college students, Yongin, South Korea: 445 males (M age = 20.48 years, SD = 1.35) and 425 females (M age = 20.12, SD = 1.24). The collected dreams were analyzed by The Sang Bok Lee Traumatic Dream Scales that were designed to differentiate ordinary dreams from traumatic and PTST-related dreams.The traumatic dreams were hypothesized as having frequently recurrent, unexpected, emotionally dreadful, and not actively coped by the dreamers.Results759 dreams (31%) of 2450 collected dreams were found as traumatic or very/extreme anxious according to The Lee Anxiety Dream Scale (Mean = 4.56). Strong positive correlation was found between 759 traumatic dreams and independent variables of traumatic dream content (unfamiliar: r = .86, p = .0001; accidental: r = .81, p = .0001; dreadful: r = .93, p = .0001, and not coped by the dreamer: r = 0.86, p = .0001).ConclusionThe contents of The Sang Bok Lee Traumatic Dream Scales were developed and validated; the results were associated with the previous publications - “Lee Acculturation Dream Scale for Korean-American College Students” (Lee, Sang Bok, 2005: Psychological Reports, 96, 454–456), The Sang Bok Lee Neurocognitive Dream Orientation Scales for Screening Traumatic and PTSD Related Dreams, and The Lee Anxiety Dream Scales.


2010 ◽  
Vol 109 (4) ◽  
pp. 1096-1101 ◽  
Author(s):  
Audrey Baguet ◽  
Jan Bourgois ◽  
Lander Vanhee ◽  
Eric Achten ◽  
Wim Derave

The role of the presence of carnosine (β-alanyl-l-histidine) in millimolar concentrations in human skeletal muscle is poorly understood. Chronic oral β-alanine supplementation is shown to elevate muscle carnosine content and improve anaerobic exercise performance during some laboratory tests, mainly in the untrained. It remains to be determined whether carnosine loading can improve single competition-like events in elite athletes. The aims of the present study were to investigate if performance is related to the muscle carnosine content and if β-alanine supplementation improves performance in highly trained rowers. Eighteen Belgian elite rowers were supplemented for 7 wk with either placebo or β-alanine (5 g/day). Before and following supplementation, muscle carnosine content in soleus and gastrocnemius medialis was measured by proton magnetic resonance spectroscopy (1H-MRS) and the performance was evaluated in a 2,000-m ergometer test. At baseline, there was a strong positive correlation between 100-, 500-, 2,000-, and 6,000-m speed and muscle carnosine content. After β-alanine supplementation, the carnosine content increased by 45.3% in soleus and 28.2% in gastrocnemius. Following supplementation, the β-alanine group was 4.3 s faster than the placebo group, whereas before supplementation they were 0.3 s slower ( P = 0.07). Muscle carnosine elevation was positively correlated to 2,000-m performance enhancement ( P = 0.042 and r = 0.498). It can be concluded that the positive correlation between baseline muscle carnosine levels and rowing performance and the positive correlation between changes in muscle carnosine and performance improvement suggest that muscle carnosine is a new determinant of rowing performance.


2020 ◽  
Author(s):  
Eid S. Alshammari ◽  
Amjad A. Aljagthmi ◽  
Andrew J. Stacy ◽  
Mike Bottomley ◽  
H. Nicholas Shamma ◽  
...  

Abstract Background: p63, a member of the p53 gene family, is an important regulator for epithelial tissue growth and development. ∆Np63α is the main isoform of p63 and highly expressed in Non-melanoma skin cancer (NMSC). Extracellular signal-regulated kinase 3 (ERK3) is an atypical mitogen-activated protein kinase (MAPK) whose biochemical features and cellular regulation are distinct from those of conventional MAPKs such as ERK1/2. While ERK3 has been shown to be upregulated in lung cancers and head and neck cancers, in which it promotes cancer cell migration and invasion, little is known about the implication of ERK3 in NMSCs. Methods: Fluorescent immunohistochemistry was performed to evaluate the expression levels of DNp63a and ERK3 in normal and NMSC specimens. Dunnett’s test was performed to compare mean fluorescence intensity (MFI, indicator of expression levels) of p63 or ERK3 between normal cutaneous samples and NMSC samples (i.e., Actinic Keratosis (AK), a precursor to invasive squamous cell carcinoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC)). A mixed effects (ANOVA) test was used to determine the correlation between DNp63a and ERK3 expression levels (MFI). The regulation of ERK3 by DNp63a was studied by qRT-PCR, Western blot and luciferase assay. The effect of ERK3 regulation by DNp63a on cell migration was measured by performing trans-well migration assay. Results: The expression levels of both ∆Np63α and ERK3 proteins are upregulated in NMSCs compared to normal tissues. There is a strong positive correlation between ∆Np63α and ERK3 expression in normal skin and patients with AK, SCC and BCC. Further, we found that ∆Np63α positively regulates ERK3 transcript and protein levels in A431 and HaCaT skin cells, underlying the upregulation of ERK3 expression and its positive correlation with ∆Np63α in NMSCs. Moreover, similar to the effect of ∆Np63α depletion, silencing ERK3 greatly enhanced A431 cell migration. Restoration of ERK3 expression under the condition of silencing ∆Np63α counteracted the increase in cell migration induced by the depletion of ∆Np63α. Conclusions: ERK3 is positively regulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in NMSC.


This study employs structural equations modeling via PLS to analyze the 732 valid questionnaires in order to assess the proposed model that is based on the organizational motivation characteristics to identify its effect on the performance of employees in the government sector in Dubai. The main independent constructs in the model are intrinsic motivation and external motivation. The dependent construct is employee performance. The study will describe relations among the various constructs. Our work has improved our insight in the importance of organizational motivation. Results indicated that both independent variables significantly predicted employee performance with a various percentage. The proposed model explained 37.7% of the variance in employee performance.


BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Eid S. Alshammari ◽  
Amjad A. Aljagthmi ◽  
Andrew J. Stacy ◽  
Mike Bottomley ◽  
H. Nicholas Shamma ◽  
...  

Abstract Background p63, a member of the p53 gene family, is an important regulator for epithelial tissue growth and development. ∆Np63α is the main isoform of p63 and highly expressed in Non-melanoma skin cancer (NMSC). Extracellular signal-regulated kinase 3 (ERK3) is an atypical mitogen-activated protein kinase (MAPK) whose biochemical features and cellular regulation are distinct from those of conventional MAPKs such as ERK1/2. While ERK3 has been shown to be upregulated in lung cancers and head and neck cancers, in which it promotes cancer cell migration and invasion, little is known about the implication of ERK3 in NMSCs. Methods Fluorescent immunohistochemistry was performed to evaluate the expression levels of ΔNp63α and ERK3 in normal and NMSC specimens. Dunnett’s test was performed to compare mean fluorescence intensity (MFI, indicator of expression levels) of p63 or ERK3 between normal cutaneous samples and NMSC samples. A mixed effects (ANOVA) test was used to determine the correlation between ΔNp63α and ERK3 expression levels (MFI). The regulation of ERK3 by ΔNp63α was studied by qRT-PCR, Western blot and luciferase assay. The effect of ERK3 regulation by ΔNp63α on cell migration was measured by performing trans-well migration assay. Results The expression level of ∆Np63α is upregulated in NMSCs compared to normal tissue. ERK3 level is significantly upregulated in AK and SCC in comparison to normal tissue and there is a strong positive correlation between ∆Np63α and ERK3 expression in normal skin and skin specimens of patients with AK, SCC or BCC. Further, we found that ∆Np63α positively regulates ERK3 transcript and protein levels in A431 and HaCaT skin cells, underlying the upregulation of ERK3 expression and its positive correlation with ∆Np63α in NMSCs. Moreover, similar to the effect of ∆Np63α depletion, silencing ERK3 greatly enhanced A431 cell migration. Restoration of ERK3 expression under the condition of silencing ∆Np63α counteracted the increase in cell migration induced by the depletion of ∆Np63α. Mechanistically, ERK3 inhibits the phosphorylation of Rac1 G-protein and the formation of filopodia of A431 skin SCC cells. Conclusions ERK3 is positively regulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in NMSC.


Author(s):  
Enver Atay ◽  
Suna Kılınç ◽  
Gozde Ulfer ◽  
Turkan Yigitbasi ◽  
Cagri Cakici ◽  
...  

Abstract Background There is no data regarding the interrelationships of circulating Makorin Ring Finger Protein-3 (MKRN3), Kisspeptin (KISS1), and Neurokinin B (NKB) concentrations during minipuberty in humans. Objective To determine temporal changes in circulating concentrations of MKRN3, KISS1, NKB, and gonadotropins and investigate interrelationships between them in healthy full-term (FT) and preterm (PT) infants during minipuberty period. Methods A prospective study of 6-month follow-up performed. Eighty-seven healthy newborns, 48 FT (19 boys/29 girls), and 39 PT (21 boys/18 girls) (gestational age 31–37 weeks), were included. Blood samples were taken at 7 days (D7), 2 months (M2), and 6 months (M6) of age. Serum MKRN3, KISS1, NKB, LH, FSH, total testosterone (TT), and estradiol (E2) concentrations were measured. Results Seventy infants completed the study. MKRN3, KISS1, and NKB concentrations were similar in FT girls and boys. PT boys and girls also had similar concentrations of MKRN3, KISS1, and NKB. FT babies had significantly higher NKB concentrations than PT babies at D7, M2, and M6. MKRN3 and KISS1 concentrations do not differ between FT and PT babies. A strong positive correlation was found between MKRN3 and KISS1 at each time point and in all groups. FSH, LH, TT/E2 concentrations decrease while those of MKRN3 and KISS1 have a trend to increase toward the end of minipuberty. No correlation was detected between gonadotropins and MKRN3, KISS1, NKB concentrations. Conclusion Strong positive correlation demonstrated between KISS1 and MKRN3 suggests that interrelationship between molecules controlling minipuberty is not similar to those at puberty.


2020 ◽  
Author(s):  
Eid S. Alshammari ◽  
Amjad A. Aljagthmi ◽  
Andrew J. Stacy ◽  
Mike Bottomley ◽  
H. Nicholas Shamma ◽  
...  

Abstract Background: p63, a member of the p53 gene family, is an important regulator for epithelial tissue growth and development. ∆Np63α is the main isoform of p63 and highly expressed in Non-melanoma skin cancer (NMSC). Extracellular signal-regulated kinase 3 (ERK3) is an atypical mitogen-activated protein kinase (MAPK) whose biochemical features and cellular regulation are distinct from those of conventional MAPKs such as ERK1/2. While ERK3 has been shown to be upregulated in lung cancers and head and neck cancers, in which it promotes cancer cell migration and invasion, little is known about the implication of ERK3 in NMSCs. Methods: Fluorescent immunohistochemistry was performed to evaluate the expression levels of DNp63a and ERK3 in normal and NMSC specimens. Dunnett’s test was performed to compare mean fluorescence intensity (MFI, indicator of expression levels) of p63 or ERK3 between normal cutaneous samples and NMSC samples. A mixed effects (ANOVA) test was used to determine the correlation between DNp63a and ERK3 expression levels (MFI). The regulation of ERK3 by DNp63a was studied by qRT-PCR, Western blot and luciferase assay. The effect of ERK3 regulation by DNp63a on cell migration was measured by performing trans-well migration assay. Results: The expression level of ∆Np63α is upregulated in NMSCs compared to normal tissue. ERK3 level is significantly upregulated in AK and SCC in comparison to normal tissue and there is a strong positive correlation between ∆Np63α and ERK3 expression in normal skin and skin specimens of patients with AK, SCC or BCC. Further, we found that ∆Np63α positively regulates ERK3 transcript and protein levels in A431 and HaCaT skin cells, underlying the upregulation of ERK3 expression and its positive correlation with ∆Np63α in NMSCs. Moreover, similar to the effect of ∆Np63α depletion, silencing ERK3 greatly enhanced A431 cell migration. Restoration of ERK3 expression under the condition of silencing ∆Np63α counteracted the increase in cell migration induced by the depletion of ∆Np63α. Mechanistically, ERK3 inhibits the phosphorylation of Rac1 G-protein and the formation of filopodia of A431 skin SCC cells.Conclusions: ERK3 is positively regulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in NMSC.


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ayah Abdelaziz Ali Hassan ◽  
Amany Moh. Rashad Abdel-Aziz ◽  
Tougan Taha Abdel Aziz ◽  
Sameh Roshdy Twadros ◽  
Fady Mamdouh

Abstract Background Glioma is the most common intracranial primary tumor of central nervous system (CNS) and accounts for about 70% of primary adult malignant brain tumors. The optimum therapeutic treatment and prognosis evaluation largely depends on the tumor pathological grades. Objective To evaluate the role of susceptibility weighted imaging (SWI) in grading of cerebral gliomas. The magnetic resonance imaging (MRI) results were compared and correlated to the pathology results to evaluate its role. The pathological grading of the glioma was done according to WHO 2007 classification system. Patients and Methods This was a retrospective study that included 35 adult patients, (11females & 24 males), their ages ranging from 18 years to 73 years. They were pathologically proven glioma patients ranging from grade I to grade IV. All the patients were referred from neurosurgeon to our radiology center (private center). This study was carried out during the period between January 2017 and November 2018. Results In our study, there were a strong positive correlation between both conventional imaging and pathological grading and between pathological and SWI grading. Using SWI sequence in grading of glioma will be very beneficial in patients with contraindication to contrast. Conclusion SWI using 3T MR system may provide quite useful information for preoperative glioma grading. There seems to be a strong positive correlation between pathological grading and SWI grading system for glioma. The main disadvantage for SWI is the extra time added to the usual time of routine MRI protocol used in cases of intra cranial space occupying lesions (SOL).


2006 ◽  
Author(s):  
Lawrence C. Perlmuter ◽  
Carissa M. Dimaculangan ◽  
Julia M. Gabhart ◽  
Sant P. Singh ◽  
Nuzhat Chalisa
Keyword(s):  

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