Benefits to be expected from informatics in Radiotherapy

1994 ◽  
Vol 61 (1) ◽  
pp. 63-68
Author(s):  
M. Balli ◽  
V. D. Ferrari ◽  
F. Lonardi ◽  
G. Pavanato ◽  
A. De Lucchi ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Dose Distribution ◽  
State Of The Art ◽  
Dose Calculation ◽  
Target Volume ◽  
Radiotherapy Planning ◽  
Highly Qualified ◽  
3 Dimensional ◽  
Homogeneous Dose

The role of informatics in radiotherapy planning concerns dose calculation, dose distribution and quality assurance. Software research has recently developed to obtain 3-dimensional planning of treated volume and to reach more homogeneous dose distribution within radiation target volume. To increase therapeutic effectiveness, lower local relapses and reduce treatment sequelae, several quality assurance systems are being used, such as portal image analysis which allows an immediate comparison with the simulation film. Such procedures are carried out through informatics and need state-of-the-art computed systems, dedicated radiological devices and highly qualified teams as well.

Investigation on the role of integrated PET/MRI for target volume definition and radiotherapy planning in patients with high grade glioma

2014 ◽  
Vol 112 (3) ◽  
pp. 425-429 ◽  
Author(s):  
Pierina Navarria ◽  
Giacomo Reggiori ◽  
Federico Pessina ◽  
Anna Maria Ascolese ◽  
Stefano Tomatis ◽  
...  
Keyword(s):  
High Grade Glioma ◽  
Target Volume ◽  
Radiotherapy Planning ◽  
High Grade ◽  
Target Volume Definition

scholarly journals Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife

2021 ◽  
Vol 11 ◽  
Author(s):  
Jun Li ◽  
Xile Zhang ◽  
Yuxi Pan ◽  
Hongqing Zhuang ◽  
Junjie Wang ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Stereotactic Radiosurgery ◽  
Dose Distribution ◽  
Ionization Chamber ◽  
Treatment Time ◽  
Target Volume ◽  
Sensitive Volume ◽  
Passing Rates ◽  
Passing Rate ◽  
Gamma Passing Rate

PurposeThe purpose of this study is to establish and assess a practical delivery quality assurance method for stereotactic radiosurgery with Cyberknife by analyzing the geometric and dosimetric accuracies obtained using a PTW31016 PinPoint ionization chamber and EBT3 films. Moreover, this study also explores the relationship between the parameters of plan complexity, target volume, and deliverability parameters and provides a valuable reference for improving plan optimization and validation.MethodsOne hundred fifty cases of delivery quality assurance plans were performed on Cyberknife to assess point dose and planar dose distribution, respectively, using a PTW31016 PinPoint ionization chamber and Gafchromic EBT3 films. The measured chamber doses were compared with the planned mean doses in the sensitive volume of the chamber, and the measured planar doses were compared with the calculated dose distribution using gamma index analysis. The gamma passing rates were evaluated using the criteria of 3%/1 mm and 2%/2 mm. The statistical significance of the correlations between the complexity metrics, target volume, and the gamma passing rate were analyzed using Spearman’s rank correlation coefficient.ResultsFor point dose comparison, the averaged dose differences (± standard deviations) were 1.6 ± 0.73% for all the cases. For planar dose distribution, the mean gamma passing rate for 3%/1 mm, and 2%/2 mm evaluation criteria were 94.26% ± 1.89%, and 93.86% ± 2.16%, respectively. The gamma passing rates were higher than 90% for all the delivery quality assurance plans with the criteria of 3%/1 mm and 2%/2 mm. The difference in point dose was lowly correlated with volume of PTV, number of beams, and treatment time for 150 DQA plans, and highly correlated with volume of PTV for 18 DQA plans of small target. DQA gamma passing rate (2%/2 mm) was a moderate significant correlation for the number of nodes, number of beams and treatment time, and a low correlation with MU.ConclusionPTW31016 PinPoint ionization chamber and EBT3 film can be used for routine Cyberknife delivery quality assurance. The point dose difference should be within 3%. The gamma passing rate should be higher than 90% for the criteria of 3%/1 mm and 2%/2 mm. In addition, the plan complexity and PTV volume were found to have some influence on the plan deliverability.

Prostate cancer

2019 ◽  
pp. 224-262
Author(s):  
Linus Benjamin ◽  
Alison Tree ◽  
David Dearnaley
Keyword(s):  
Prostate Cancer ◽  
Treatment Outcome ◽  
Palliative Radiotherapy ◽  
Target Volume ◽  
Seminal Vesicles ◽  
Radiotherapy Planning ◽  
Radical Radiotherapy ◽  
Future Developments ◽  
Radiotherapy Treatment

Chapter 10 discusses prostate cancer and includes discussion on indications including radical radiotherapy to prostate ± seminal vesicles, pelvic radiotherapy, post-prostatectomy radiotherapy, palliative radiotherapy to prostate ± pelvis, palliative radiotherapy to metastases, and breast bud radiotherapy for the prevention or treatment of gynaecomastia, radical radiotherapy planning, target volume definition , dose distribution, implementation, verification, dose prescription, toxicity and care during treatment, the role of hormonal therapy in combination with radical radiotherapy, treatment outcome, and future developments.

scholarly journals Rapid Automated Target Segmentation and Tracking on 4D Data without Initial Contours

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Venkata V. Chebrolu ◽  
Daniel Saenz ◽  
Dinesh Tewatia ◽  
William A. Sethares ◽  
George Cannon ◽  
...  
Keyword(s):  
Software Metrics ◽  
State Of The Art ◽  
Ground Truth ◽  
Target Volume ◽  
Morphological Processing ◽  
Deformable Registration ◽  
Radiotherapy Planning ◽  
Dice Similarity Coefficient ◽  
Target Segmentation ◽  
Time Required

Purpose. To achieve rapid automated delineation of gross target volume (GTV) and to quantify changes in volume/position of the target for radiotherapy planning using four-dimensional (4D) CT.Methods and Materials. Novel morphological processing and successive localization (MPSL) algorithms were designed and implemented for achieving autosegmentation. Contours automatically generated using MPSL method were compared with contours generated using state-of-the-art deformable registration methods (usingElastix©and MIMVista software). Metrics such as the Dice similarity coefficient, sensitivity, and positive predictive value (PPV) were analyzed. The target motion tracked using the centroid of the GTV estimated using MPSL method was compared with motion tracked using deformable registration methods.Results. MPSL algorithm segmented the GTV in 4DCT images in27.0±11.1seconds per phase (512×512resolution) as compared to142.3±11.3seconds per phase for deformable registration based methods in 9 cases. Dice coefficients between MPSL generated GTV contours and manual contours (considered as ground-truth) were0.865±0.037. In comparison, the Dice coefficients between ground-truth and contours generated using deformable registration based methods were 0.909 ± 0.051.Conclusions. The MPSL method achieved similar segmentation accuracy as compared to state-of-the-art deformable registration based segmentation methods, but with significant reduction in time required for GTV segmentation.

scholarly journals Study of Analysis the Sensitivity of the Computational Environment for Radiological Research Field Size Based on Two Dimensional Dose Distribution for Water Phantom Cases

2020 ◽  
Vol 4 (2) ◽  
pp. 39-45
Author(s):  
Yati Hardiyanti ◽  
◽  
Thareq Barasabha ◽  
Choirul Anam ◽  
Novitrian Novitrian ◽  
...  
Keyword(s):  
Dose Distribution ◽  
Dose Calculation ◽  
Target Volume ◽  
Sensitivity Study ◽  
Research Field ◽  
Field Size ◽  
Radiation Beam ◽  
Water Phantom ◽  
Computational Environment ◽  
Beam Parameters

Purpose This study analysed the sensitivity of the field size from variations in the target volume dimensions, depth, and position. The variations in the target volume analysis were used to determine the width of the field size. Thus, the quality control of the radiation beam can be obtained. Materials and Methods The computed tomography (CT) image of the IBA Dose 1 type of water phantom consists of 350 slices. Variations in the dimension of the target volume were modelled in 10×10×10 cm3, 10×12×10 cm3 , 10.2×10×10.2 cm3, and 15×15×15 cm3. Beam parameters use one beam of irradiation on the central axis 0°, 6 MV energy, 100 cm source-skin distance (SSD), beamlet delta x, and y set to 0.1 cm. Dose distribution in the form of the XZ isodose curve and dose profile was used to observe the field size. Results In this study, the isodose curve was successfully displayed in the XZ isodose curve. The field size’s sensitivity has been successfully reviewed from variations of the target volume, depth, and position. The target X and Z direction analysis is used in determining the width and length of the field size. Conclusion The analysis related to the field size sensitivity study was obtained from a relatively valid calculation. The field size was evaluated with variations in depth of 1.5 cm, 5 cm, 10 cm, and variations in positions of 10 cm, 12 cm, 14 cm, 18 cm, and 20 cm. This study will be used as a reference to validate the distribution of computational environment for radiotherapy research (CERR) dose in the future. Thus, the accuracy of the dose calculation can be obtained.

scholarly journals Visualization of 4D-PET/CT, Target Volumes and Dose Distribution: Applications in Radiotherapy Planning

2014 ◽  
Author(s):  
Matthias Schlachter ◽  
Tobias Fechter ◽  
Ursula Nestle ◽  
Katja Bühler
Keyword(s):  
Dose Distribution ◽  
Visual Information ◽  
Radiation Treatment ◽  
Target Volume ◽  
Radiotherapy Planning ◽  
Medical Doctors ◽  
Visualization System ◽  
Volume Delineation ◽  
Pet Ct ◽  
Target Volumes

In radiation treatment (RT) planning medical doctors need to consider a variety of information sources for anatomical and functional target volume delineation. The validation and inspection of the defined target volumes and the resulting RT plan is a complex task, especially in the presence of moving target areas as it is the case for tumors of the chest and the upper abdomen. A 4D-PET/CT visualization system may become a helpful tool for validating RT plans. We define major requirements such a visualization system should fulfill to provide medical doctors with the necessary visual information to validate tumor delineations, and review the dose distribution of a RT plan. We present an implementation of such a system, and present qualitative results of its applications for a lung cancer patient.

scholarly journals O2.02 * ROLE OF AN INTEGRATED IMAGING FOR TARGET VOLUME DEFINITION AND RADIOTHERAPY PLANNING IN PATIENTS WITH DIAGNOSED HIGH GRADE GLIOMA

2014 ◽  
Vol 16 (suppl 2) ◽  
pp. ii3-ii3
Author(s):  
P. Navarria ◽  
F. Pessina ◽  
S. Tomatis ◽  
P. Mancosu ◽  
A. Ascolese ◽  
...  
Keyword(s):  
High Grade Glioma ◽  
Target Volume ◽  
Radiotherapy Planning ◽  
High Grade ◽  
Target Volume Definition

Role of radiation dose distribution inside the target volume in radiosurgery

2009 ◽  
Vol 71 (1) ◽  
pp. 146
Author(s):  
N. Massager ◽  
L. Abeloos ◽  
C. Maris ◽  
O. Dewitte ◽  
D. Devriendt
Keyword(s):  
Radiation Dose ◽  
Dose Distribution ◽  
Target Volume

Quality assurance and quality improvement in medical practice – Part 1. Definition and importance of quality in medical practice

2012 ◽  
Vol 153 (3) ◽  
pp. 83-92
Author(s):  
Sándor Gődény
Keyword(s):  
Quality Assurance ◽  
Health Status ◽  
Quality Management ◽  
Medical Practice ◽  
Quality Measurement ◽  
The European Union ◽  
Management Quality ◽  
Hungarian Population ◽  
Healthcare Finance

In Hungary healthcare finance has decreased in proportion with the GDP, while the health status of the population is still ranks among the worst in the European Union. Since healthcare finance is not expected to increase, the number of practicing doctors per capita is continuously decreasing. In the coming years it is an important question that in this situation what methods can be used to prevent further deterioration of the health status of the Hungarian population, and within this is the role of the quality approach, and different methods of quality management. In the present and the forthcoming two articles those standpoints will be summarized which support the need for the integration of quality assurance in the everyday medical practice. In the first part the importance of quality thinking, quality management, quality assurance, necessity of quality measurement and improvement, furthermore, advantages of the quality systems will be discussed. Orv. Hetil., 2012, 153, 83–92.

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