Bronchial Hyperresponsiveness in Adults with Seasonal and Perennial Rhinitis: Is There a Link for Asthma and Rhinitis?

Epidemiological studies have shown that asthma and rhinitis often coexist in the same patients and the prevalence of asthma is greater in patients with rhinitis. The aim of this study was to evaluate the differences in bronchial reactivity in subjects with seasonal and perennial rhinitis. We enrolled 128 subjects with seasonal or perennial allergic rhinitis divided into three groups: A with perennial rhinitis and allergy to “Dermatophagoides Pteronissynus”; B with seasonal rhinitis and allergy to “Graminae” and “Parietaria”, who underwent methacholine challenge test (MCHt) during the exposure period (fron March until May); C with seasonal rhinitis and allergy to “Graminae” and “Parietaria”, who underwent MCHt during the non exposure period (from June until February). The PC20 mean values of group A (1774.8 ± 20.7) and group B (1740.7 ± 38.8) were not significantly different, but significantly lower than those of group C (3010.0 ± 56.9) (p=0.001). The subjects with group A were positive to the MCHt in 54.54%, against 29.28% of group B and 11.62% of group C (p=0.007). The results show differences in the degree of bronchial responsiveness. The dose-response curves documented a lower value of PC20 in the group with perennial rhinitis and a statistically significant difference of bronchial hyperresponsiveness prevalence between the three groups (p=0.007).

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Urinary excretion of glycated protein determined with a specific radioimmunoassay

Clinical Chemistry ◽

10.1093/clinchem/37.4.504 ◽

1991 ◽

Vol 37 (4) ◽

pp. 504-507 ◽

Cited By ~ 2

Author(s):

Chizuko Ukita ◽

Mitsushige Nishikawa ◽

Akira Shouzu ◽

Mitsuo Inada

Keyword(s):

Urinary Excretion ◽

Normal Subjects ◽

Mean Values ◽

Specific Radioimmunoassay ◽

Glycated Protein ◽

Highly Sensitive ◽

Significant Difference ◽

Group A ◽

The Mean ◽

Group B

Abstract We developed a simple and highly sensitive RIA for glycated protein (GP), and used it to measure GP in serum and urine from 15 normal controls and 30 diabetics (14 with urinary excretion rate of albumin, Ualb less than 15 micrograms/min, group A; nine with 15 less than or equal to Ualb less than or equal to 150 micrograms/min, group B; and seven with Ualb greater than 150 micrograms/min, group C). The mean serum concentration of GP was above normal in all groups of diabetics, and the mean glycation ratios of serum protein (SGP) were higher in groups B and C than in normal subjects. Urinary concentrations of GP also were increased in groups B and C, although the glycation ratio of urinary protein (UGP) was decreased in group C. Consequently, the selectivity of urinary excretion of GP (UGP/SGP) was significantly decreased in group C. Moreover, there was a significant difference in the mean values of selectivity between groups of patients with various degrees of retinopathy. We suggest that measurements of serum and urinary GP are useful to evaluate the progression of diabetic complications.

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Effectiveness of Pilates exercises on non-specific low back pain to determine pain and disability

Biomedicine ◽

10.51248/.v41i4.1361 ◽

2021 ◽

Vol 41 (4) ◽

pp. 825-829

Author(s):

P Manikandan ◽

G Mohan Kumar ◽

V Rajalaxmi ◽

C Priya ◽

G Yuvarani ◽

...

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Functional Disability ◽

Conventional Group ◽

Patient Specific ◽

Low Back ◽

Mean Values ◽

Significant Difference ◽

Group A ◽

Group B

Introduction and Aim: Low back discomfort is one of the commonest musculoskeletal problems. The Pilates exercises are an approach to stretching and strengthening techniques and specifically train all the core muscles. The intend of the current study was to verify the influences of the Pilates exercises among pain and disability among patients with Non-specific Low Back Pain (NSLBP). Materials and Methods: A 100 non-specific low back pain subjects were randomly selected for this experimental study. The study includes of non-specific LBP age group between 25 to 40 years, both male and female patients with pain and disability and this study excludes spinal fractures and Pregnant Women. The estimations were taken utilizing Visual Analogue scale (VAS), Patient Specific Functional Scale (PSFS) and Modified Oswestry Low Back Pain Disability Questionnaire (MODQ). Subjects are allotted in two groups, Group A (Pilates group) receives Pilate’s exercise and Group B (conventional group) receives conventional exercise. Exercises were given for 3 times a week for 12 weeks and a regular follow up was done for every 4 weeks. Results: Group A (Pilates group) were found to be more effective than Group B (conventional group). It shows a highly significant difference in mean values at P ? 0.001. This implies that Pilates exercise is more beneficial in decreasing pain and functional disability. Conclusion: On comparing the mean values, Group A (Pilates group) showed significant improvement at the end of the study when compared with Group B (conventional group).

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Masticatory Force in Relation with Age in Subjects with Full Permanent Dentition: A Cross-Sectional Study

Healthcare ◽

10.3390/healthcare9060700 ◽

2021 ◽

Vol 9 (6) ◽

pp. 700

Author(s):

Ottavia Poli ◽

Licia Manzon ◽

Tarcisio Niglio ◽

Evaristo Ettorre ◽

Iole Vozza

Keyword(s):

Periodontal Diseases ◽

Cross Sectional Study ◽

Cross Sectional ◽

Mean Values ◽

Wide Range ◽

Significant Difference ◽

Scientific Papers ◽

Group A ◽

Masticatory Force ◽

Group B

Masticatory performance is directly correlated with masticatory muscle work to grind and cut the food. Chewing efficacy is decisive to eating a variety of foods needed maintain general health status at all ages. Older people have oral problems that get worse with age. Elders have more pathologies such as periodontal diseases, caries, tooth loss and inadequate dental prostheses than younger subjects. Objectives: to investigate the correlation between masticatory bite force (MBF) and body mass index (BMI) vs. aging and sex. Methods: This study was performed on 426 subjects (213 females plus 213 male) assigned into five different groups by age. Group “A” aged from 20 to 35 years; group “B” aged 45–59 years; group “C” aged 60–69 years; group “D” aged 70–79 years; and group “E” aged more than 79 years. Results: There were not statistically significant differences in right-side MBF versus left-side MBF. The differences between sex were statistically significant with a stronger bite in males than females (p < 0.05). At the same time, younger subjects had a stronger bite than elders (p < 0.05). In group “E”, more corpulent subjects (BMI > 25) had an MBF higher than less corpulent subjects (BMI < 25, p < 0.05). The analysis of mean MBF showed a statistically significant difference within all groups stratified by BMI with mean values inversely proportional with age (p < 0.001). Conclusion: The results in our study confirm data from many scientific papers. The importance of the present paper was to correlate data between and within a large sample with a wide range of ages. Our sample subjects had a 31%–33% decrease in MBF from group “A” to group “E” group, but they all had full permanent dentation and they preserved a valid MBF.

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Effect of Final Irrigation Protocol on Dentin Microhardness

Biomedical & Pharmacology Journal ◽

10.13005/bpj/1596 ◽

2018 ◽

Vol 11 (4) ◽

pp. 2157-2162

Author(s):

Farah Salahalden Abbas ◽

Nadeen Jamal Abdulredah ◽

Amer Salman Hassan

Keyword(s):

Citric Acid ◽

Hardness Test ◽

Acrylic Resin ◽

Acid Group ◽

Distilled Water ◽

Mean Values ◽

Canal Irrigation ◽

Significant Difference ◽

Group A ◽

Group B

Endodontic therapy is essentially a debridement procedure that requires the removal of the irritants of the canal and periapical tissue if success is to be gained. The debridement may include instrumentation of the canal, placement of medicament and irrigants. Complete cleaning of the root-canal system requires the use of irrigants that dissolve organic and inorganic material. The study aimed to evaluate changes in dentin microhardness after canal irrigation with different solutions. Twenty four freshly extracted human mandibular molars (distal roots with single canals) were used. 10mm root length was taken as standard length. The roots were embedded into auto polymerizing acrylic resin using plastic molds before the canals preparation and micro hardness test. The distal roots were prepared with one shape rotary file. Before the preparation each root was irrigated with 1ml distilled water. Then the roots were divided into four groups according to the final irrigation protocol: Group A: NaOCl 2.5%, Group B: EDTA 17%, Group C: Citric Acid 40%, Group D: Distilled Water. For (Vicker microhardness test) the same load and time 500 g test load for 20 seconds, will be conducted three times at distance 0.5mm from canal lumen ; thus there will be 9 indentations on each specimen surface. An average of the three readings for each test condition will be recorded as the VHN value of a specimen. Comparing all four groups statistically there was no significant difference among them. The mean values were found more reduced in EDTA group followed by NaOCL group, and then Control and Citric Acid groups. All the groups showed reduction in dentin microhardness. EDTA group showed the maximum reduction followed by NaOCL group, and least with Citric Acid group.

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Efficacy of motor therapy over sensorimotor therapy in upper limb functions of post stroke patients

Biomedicine ◽

10.51248/.v41i1.545 ◽

2021 ◽

Vol 41 (1) ◽

pp. 120-124

Author(s):

V. Rajalaxmi ◽

M. Tharunya ◽

S.S. Subramanian ◽

G. Vaishnavi ◽

Chandra Kumar K ◽

...

Keyword(s):

Upper Limb ◽

Fine Motor ◽

Stroke Patients ◽

Mean Values ◽

Post Stroke ◽

Medical College ◽

Significant Difference ◽

Group A ◽

Group B ◽

Nine Hole Peg Test

Introduction and Aim:Strokeis one of the leading causes of death and disability in India. The incidence of stroke rapidly increases with age, doubling for each decade after 55.In the majority of patients the upper limb is severely impaired than lower limb. The aim of this study was to analyze the efficacy of motor therapy over sensorimotor therapy in upper limb functions of post stroke patients. Materials and Methods: This was an experimental study, of pre-post type, that was conducted in the outpatient department of Physiotherapy at ACS Medical College and Hospital,chennai.30 samples were selected from 45 volunteers according to inclusion criteria and the study was conducted for Group A received sensorimotor therapy for one session/day for 6 days a week for 12 weeks. Group B received motor therapy for one session/day for 6 days a week for 12 weeks. Pre and post measurement were done using motor assessment scale, stroke upper limb capacity scale, action research arm test and nine-hole peg test. Results: There was a significant difference in mean values of group A and B on comparison. Group A seems to be more effective than group B. Conclusion: The study concludes that both motor therapy and sensorimotor therapy are beneficial in stroke rehabilitation, but sensorimotor therapy is more effective in improving the gross and fine motor skills of the upper limb of stroke patients.

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Seroepidemiology ofStrongyloides stercoralisin Dhaka, Bangladesh

Parasitology ◽

10.1017/s0031182012000753 ◽

2012 ◽

Vol 139 (11) ◽

pp. 1513-1520 ◽

Cited By ~ 8

Author(s):

YASMIN SULTANA ◽

GWENDOLYN L. GILBERT ◽

BE-NAZIR AHMED ◽

ROGAN LEE

Keyword(s):

Strongyloides Stercoralis ◽

Epidemiological Studies ◽

Igg Subclasses ◽

Personal Hygiene ◽

Individual Risk ◽

Slum Dwellers ◽

Significant Difference ◽

History Of ◽

Group A ◽

Group B

SUMMARYHuman strongyloidiasis is a neglected tropical disease with global distribution and this infection is caused by the parasitic nematodeStrongyloides stercoralis. The aim of this study was to determine the prevalence of strongyloidiasis in Dhaka, Bangladesh. Sera from 1004 residents from a slum (group A) and 299 from city dwellers (group B) were tested for total IgG and IgG subclasses toStrongyloidesantigen. There was a significant difference (P < 0·001) in IgG seroprevalence between group A (22%) and group B (5%). Reactive IgG subclasses (IgG1 and IgG4) were also higher in group A (P < 0·05). The seroprevalence of strongyloidiasis in group A increased with age but was unrelated to sex. The presence of reactive IgG toStrongyloidesantigen had no correlation with either socio-economic or personal hygiene factors. However, a history of diarrhoea in a family member, in the past 6 months, but not in the respondents was associated with detection of antibodies toS. stercoralis(P < 0·01). None of the sera from either group had an HTLV-I reaction. This study demonstrates that strongyloidiasis is prevalent in Dhaka, especially among slum dwellers, but concurrent infection with HTLV-I was not found. Future epidemiological studies should identify individual risk factors and other communities at risk so that appropriate interventions can be planned.

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Efficacy and safety of iontophoresis combined sodium salicylate in acquired plantar keratoderma-a randomized controlled study

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20214919 ◽

2021 ◽

Vol 8 (1) ◽

pp. 101

Author(s):

Shreya P. Somani ◽

Bhavsh N. Astik ◽

Hita H. Mehta ◽

Milan D. Jhavar

Keyword(s):

Sodium Salicylate ◽

Randomized Controlled Study ◽

Treatment Modalities ◽

Controlled Study ◽

Mean Values ◽

Randomized Controlled ◽

Number Of Patients ◽

Significant Difference ◽

Group A ◽

Group B

Background: Palmoplantar keratoderma is a heterogenous group of disorders, hereditary or acquired, characterized by thickening of palms and soles. Though it is not a life-threatening condition, it affects individual’s quality of life. As treatment of keratoderma has always been troublesome, upgraded treatment modalities which improves keratoderma efficiently are always encouraged.Methods: In this randomized controlled study, patients of plantar keratoderma of age group of 18-65 years were randomly divided in group A and group B. In group A, iontophoresis combined sodium salicylate was offered to patients twice weekly for 8 weeks of duration, during which DC current was supplied at 5-15 mA for 10 min of duration. Whereas, in group B patients applied topical salicylic acid 12% ointment at home twice a day for 8 weeks.Results: Our study of 70 patients of keratoderma, revealed diffuse (94%) pattern of involvement with female preponderance (55.7%) and occupation wise, most common among laborers (54.2%) followed by housewives (27.1%). Statistically significant number of patients showed reduction in severity grading of parameters, in both groups at end of 8 weeks. Same way, mean values of parameter grading significantly reduced at 8 weeks in both the groups. But intergroup values showed no significant difference. Mean EASI (Eczema Area Severity Index) score showed statistically significant reduction in group B as compared to group A at 8th week. Percentage of reduction of EASI score was also significantly higher in group B at end of treatment.Conclusions: Here both treatment modalities are safe and effective, topical being slightly more efficacious than iontophoresis. So, we can conclude that no additional privilege of drug delivery through iontophoresis.

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Abstract 4121: Clomipramine Infusion During Tilt Test To Imply The Neurocardiogenic Origin Of Syncopes And Presyncopes Of Unknown Aetiology

Circulation ◽

10.1161/circ.118.suppl_18.s_834 ◽

2008 ◽

Vol 118 (suppl_18) ◽

Author(s):

Gael Cinquetti ◽

Eric Perrier ◽

Jacques Deroche ◽

Olivier Manen ◽

Michel Lerecouvreux ◽

...

Keyword(s):

Blood Pressure ◽

Challenge Test ◽

Tilt Test ◽

Unknown Aetiology ◽

Significant Difference ◽

Group A ◽

Head Up Tilt ◽

Drug Challenge ◽

Group B ◽

Type 3

The aim of this study was to prospectively evaluate the diagnostic accuracy for neurocardiogenic syncopes (NCS) of two Head-Up Tilt table test (HUT) strategies in 991 patients with syncopes/presyncopes of unknown aetiology after negative clinical and non invasive investigations. HUT is a widely accepted tool in the evaluation of patients with evidence of VVS but questions remain about the sensitivity and the use of provocative agents.Clomipramine (CP), a serotonin re-uptake inhibitor, was recently proposed as a new drug challenge test for the diagnosis of neurocardiogenic syncope (NCS). Group A : the first 341 pts (207 male ; mean age = 49,9 ± 23 years) were passively tilted at 60° for 30 minutes (min), then for 15 min with 2 μg/min isoproterenol infusion rate. Group B : the following 650 pts (383 male ; mean age = 48,3 ± 21 years) were tilted at 60° for 20 min with 5 mg CP infused during the first 5 min of tilt. A positive HUT was defined as reproducting the patient’s syncope or presyncope, associated with an abrupt fall in blood pressure (systolic blood pressure <80 mmHg) and/or concomitant bradycardia (<50 beats/min). Positives responses were classified in 3 types according to the Brignole’s modification of the VASIS classification. There was no significant difference between group A/B in sex or age. Group A : Positive HUT* : 103 (Sensitivity : 30,2%) Group B : Positive HUT* : 382 (Sensitivity : 58,8 %) (*) type 1 : 36 vs 157 ; type 2A : 8 vs 13 ; Type 2B: 9 vs 57 (14,9%) ; Type 3 : 50 vs 155. No adverse effect was noticed. CP during HUT increase significantly the accuracy of the test for NCS diagnosis, especially for type 2B answers, and patients <30 yo. The duration of the test is notably shortened, and the tolerance is remarkable. If previously reported specificity (87 to 94%) was confirmed, CP-HUT might be the most valuable tool in the evaluation of pts with syncopes/presyncopes of unknown aetiology.

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Efficacy of sub-occipital muscles decompression techniques in restoring functional walking capacity in hemiplegic cerebral palsy children

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20172657 ◽

2017 ◽

Vol 4 (4) ◽

pp. 1132

Author(s):

Ahmed M. Azam

Keyword(s):

Cerebral Palsy ◽

Relevant Literature ◽

Mean Values ◽

Physiotherapy Program ◽

Hemiplegic Cerebral Palsy ◽

Significant Difference ◽

Walking Capacity ◽

Group A ◽

The Difference ◽

Group B

Background: This work was carried out to investigate the efficacy of sub-occipital muscles decompression in restoring functional walking capacity in hemiplegic cerebral palsy children.Methods: Thirty children were enrolled in this study and randomly assigned into two groups; group A (sub-occipital muscles decompression techniques plus traditional physiotherapy program) and group B (Traditional physiotherapy program only). 6 minutes walking test (6MWT) was used to quantify, evaluate and follow functional walking capacity also flexibility tests were used to detect and follow hamestring and calf muscles elasticity. This measurement was taken before treatment and after 12 weeks of treatment for all patients. The children parents in both groups A and B were instructed to complete 3 hours of home routine program.Results: Data analysis was available on the 30 hemiplegic cerebral palsy children participated in the study. No significant difference was recorded between the mean values of all parameter of the two groups before treatment. By comparison of the two groups 'results after treatment there was significant improvement in functional walking capacity in favor of the study group. The difference between pre-and post-treatment results of each group was significant.Conclusions: According to the results of this study supported by the relevant literature it can be concluded that the combined effect of physiotherapy training program in addition to sub-occipital muscles decompression techniques can be recommended in restoring functional walking capacity in hemiplegic cerebral palsy children.

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Swimming and Persons with Mild Persistant Asthma

The Scientific World JOURNAL ◽

10.1100/tsw.2007.221 ◽

2007 ◽

Vol 7 ◽

pp. 1182-1188 ◽

Cited By ~ 29

Author(s):

Mirjana Arandelovic ◽

Ivana Stankovic ◽

Maja Nikolic

Keyword(s):

Lung Function ◽

Inhaled Corticosteroids ◽

Bronchial Hyperresponsiveness ◽

Persistent Asthma ◽

Forced Expiratory Volume ◽

Control Group ◽

Significant Difference ◽

Group A ◽

Mild Persistent Asthma ◽

Group B

The aim of our study was to analyze the effect of recreational swimming on lung function and bronchial hyperresponsiveness (BHR) in patients with mild persistent asthma. This study included 65 patients with mild persistent asthma, who were divided into two groups: experimental group A (n = 45) and control group B (n = 20). Patients from both groups were treated with low doses of inhaled corticosteroids (ICS) and short-acting β2 agonists salbutamol as needed. Our program for patients in group A was combined asthma education with swimming (twice a week on a 1-h basis for the following 6 months). At the end of the study, in Group A, we found a statistically significant increase of lung function parameters FEV1 (forced expiratory volume in 1 sec) (3.55 vs. 3.65) (p < 0.01), FVC (forced vital capacity) (4.27 vs. 4.37) (p < 0.05), PEF (peak expiratory flow) (7.08 vs. 7.46) (p < 0.01), and statistically significant decrease of BHR (PD200.58 vs. 2.01) (p < 0.001). In Group B, there was a statistically significant improvement of FEV1 3.29 vs. 3.33 (p < 0.05) and although FVC, FEV1/FVC, and PEF were improved, it was not significant. When Groups A and B were compared at the end of the study, there was a statistically significant difference of FVC (4.01 vs. 4.37), FEV1 (3.33 vs. 3.55), PEF (6.79 vs.7.46), and variability (p <0.001), and statistically significantly decreased BHR in Group A (2.01 vs. 1.75) (p < 0.001). Engagement of patients with mild persistent asthma in recreational swimming in nonchlorinated pools, combined with regular medical treatment and education, leads to better improvement of their parameters of lung function and also to more significant decrease of their airway hyperresponsiveness compared to patients treated with traditional medicine

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