The Rational Use of Psychotropic Drugs in Pregnancy and Postpartum

1986 ◽  
Vol 31 (3) ◽  
pp. 183-190 ◽  
Author(s):  
Gail Erlick Robinson ◽  
Donna E. Stewart ◽  
Edred Flak
Keyword(s):  
Pregnant Woman ◽  
Psychotropic Medication ◽  
Psychotropic Drugs ◽  
Teratogenic Effects ◽  
Rational Use ◽  
Nursing Mother ◽  
Pregnancy And Postpartum ◽  
Withdrawal Effects ◽  
Breast Fed ◽  
In Pregnancy

When a pregnant woman or nursing mother requires psychotropic medication, one must consider the effect of such medications on the fetus or baby. The authors review the evidence for teratogenic effects of such drugs given during pregnancy, toxic or withdrawal effects in the newborn and dangers to the breast-fed baby. Suggestions are made for judicious use of psychotropic drugs in pregnant or nursing women.

scholarly journals Prescribing in pregnancy

2008 ◽  
Vol 192 (5) ◽  
pp. 321-322 ◽  
Author(s):  
Carol Paton
Keyword(s):  
Mental Illness ◽  
Pregnant Woman ◽  
Psychotropic Drugs ◽  
Treatment Plan ◽  
Morbidity And Mortality ◽  
Maternal Mental Illness ◽  
In Pregnancy

SummaryPsychotropic drugs reduce morbidity and mortality related to maternal mental illness but may also cause harm to the foetus, the nature and magnitude of which is not completely understood. Up-to-date information should be shared as fully as possible with the pregnant woman and a treatment plan agreed jointly.

Congenital malformations caused by psychotropic drugs in pregnancy

1994 ◽  
Vol 4 (4) ◽  
pp. 77-85
Author(s):  
G. de Cuypere ◽  
Ph. Rombaut ◽  
M. van Moffaert
Keyword(s):  
Valproic Acid ◽  
Side Effects ◽  
Psychotropic Drugs ◽  
Congenital Malformations ◽  
Epidemiological Studies ◽  
Teratogenic Effect ◽  
Teratogenic Effects ◽  
Harmful Effects ◽  
In Pregnancy

SummaryAfter a description of the harmful effects of psychotropic drugs as well as of the moments of vulnerability to any teratogenic effect, this paper reviews prospective, retrospective and epidemiological studies of the teratogenic effects of anticonvulsants (phenytoin, valproic acid, carbamazepine and barbiturates), lithium, anti-psychotics, benzodiazepines and anti-depressive agents. It is found that the results of these studies are not unequivocal. Only lithium and valproic acid are shown to be teratogenic. In cases where malformations of the fetus are observed, the treatment often consisted in a combination of various psychotropic drugs.The review is completed with data on the psychopharmacological problems during delivery and their side-effects on the newborn.

scholarly journals British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum 2017

2017 ◽  
Vol 31 (5) ◽  
pp. 519-552 ◽  
Author(s):  
R Hamish McAllister-Williams ◽  
David S Baldwin ◽  
Roch Cantwell ◽  
Abby Easter ◽  
Eilish Gilvarry ◽  
...  
Keyword(s):  
Mental Health ◽  
Psychotropic Medication ◽  
Mental Health Problems ◽  
Perinatal Period ◽  
In Utero Exposure ◽  
Consensus Guidelines ◽  
Pregnancy And Postpartum ◽  
Consensus Guidance ◽  
Specific Disorders ◽  
In Pregnancy

Decisions about the use of psychotropic medication in pregnancy are an ongoing challenge for clinicians and women with mental health problems, owing to the uncertainties around risks of the illness itself to mother and fetus/infant, effectiveness of medications in pregnancy and risks to the fetus/infant from in utero exposure or via breast milk. These consensus guidelines aim to provide pragmatic advice regarding these issues. They are divided into sections on risks of untreated illness in pregnancy; general principles of using drugs in the perinatal period; benefits and harms associated with individual drugs; and recommendations for the management of specific disorders.

Syphilis and pregnancy: Review

2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Samaniego Haro VJ ◽  
Keyword(s):  
Pregnant Woman ◽  
Congenital Syphilis ◽  
Neonatal Morbidity ◽  
Sexual Partners ◽  
Cure Rate ◽  
Chronic Complications ◽  
Drug Of Choice ◽  
Recurrent Abortions ◽  
Penicillin Treatment ◽  
In Pregnancy

Syphilis is a disease that has not been eradicated in part due to inadequate management of antibiotic therapy which is selected according to the stage of the disease and to the misuse of the type of penicillin. Treatment of this disease should be done to prevent it´s chronic complications, to avoid infecting sexual partners and the fetus in a pregnant woman. Syphilis in pregnancy causes increase in the rate of recurrent abortions and neonatal morbidity and mortality, that´s the main reason why early detection and treatment without delay is extremely important. Pregnancy alters immunity, so the serological diagnosis can provide false positives, with the use of inverse algorithms these results may decrease, by increasing the sensitivity of the tests. Today, after 69 years since the advent of penicillin, it has become the drug of choice for any stage of syphilis and in pregnant women; if the patient has allergy, desensitization is indicated either orally or intravenously and other antibiotic shouldn´t be used because of the security offered by penicillin in the cure rate and in the reduction of congenital syphilis. Keywords: Syphilis; Pregnancy; Inverse algorithms.

Seborrheic Dermatitis of Infants: Treatment with Biotin Injections for the Nursing Mother

PEDIATRICS ◽  
1969 ◽  
Vol 44 (6) ◽  
pp. 1014-1016
Author(s):  
Aaron Nisenson
Keyword(s):  
Breast Milk ◽  
Maternal Nutrition ◽  
Seborrheic Dermatitis ◽  
Cow’S Milk ◽  
Blood Levels ◽  
Biotin Deficiency ◽  
Nursing Mother ◽  
Limited Experience ◽  
The Relationship ◽  
Breast Fed

Four cases of extensive seborrheic dermatitis or Leiner's disease are presented which dramatically improved after the nursing mother was given injections of biotin. The relationship between seborrheic dermatitis in infants and biotin deficiency is discussed and the literature reviewed. From this review it appears that breast milk is deficient in biotin in comparison to cow's milk. The deficiency is further aggravated by poor maternal nutrition. Infection and diarrhea in the infant may also contribute to low blood levels of biotin. On the basis of this limited experience, injections of biotin to the nursing mother appear to be a useful treatment for the breast-fed infant with extensive seborrheic dermatitis.

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