Eligibility and patient barriers to peritoneal dialysis in patients with advanced chronic kidney disease

2021 ◽  
pp. 089686082199820
Author(s):  
Saleem Abdulkarim ◽  
Jasmit Shah ◽  
Ahmed Twahir ◽  
Ahmed P Sokwala

Introduction: The burden of chronic kidney disease (CKD) is increasing in Kenya and is a significant cause of morbidity and mortality. While definitive treatment is renal transplantation, many patients require kidney replacement therapy with haemodialysis (HD) or peritoneal dialysis (PD). The predominant modality utilized in Kenya is currently HD. There is a need to explore why PD remains underutilized and whether patient factors may be contributory to barriers that limit the uptake of PD. Methods: This was a descriptive cross-sectional study where patients with advanced CKD were assessed by a multidisciplinary team for PD eligibility using a standardized tool. Contraindications and barriers to the modality were recorded as was the presence or absence of support for the provision of PD. Demographic and clinical data were recorded using a standardized questionnaire. The impact of support on PD eligibility was determined. Results: We found that 68.9% patients were eligible for PD. Surgery-related abdominal scarring was the most common contraindication. Barriers to PD were identified in 45.9% and physical barriers were more common than cognitive barriers. Presence of support was associated with a significant increase in PD eligibility ( p < 0.001). Conclusion: The rate of eligibility for PD in this study was similar to that found in other populations. Surgical-related factors were the most commonly identified contraindication. Physical and cognitive barriers were commonly identified and may be overcome by the presence of support for PD.

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e027752
Author(s):  
Hirotaka Ochiai ◽  
Takako Shirasawa ◽  
Takahiko Yoshimoto ◽  
Satsue Nagahama ◽  
Mariko Kobayashi ◽  
...  

ObjectivesWeight gain after 20 years of age is associated with chronic kidney disease (CKD). However, the impact of weight gain on CKD might differ by current obesity status. We investigated the association of the combination of weight gain after 20 years of age and current obesity with CKD among adults in Japan.DesignA cross-sectional study.Setting and participantsWe analysed data from 94 822 adults aged 40–64 years who had an annual health check-up in Japan from April 2013 to March 2014.Primary outcome measureCKD was defined as an estimated glomerular filtration rate <60 mL/min/1.73 m2and/or proteinuria.ResultsBoth weight gain ≥10 kg after 20 years of age plus obesity (OR 2.21, 95% CI 2.07 to 2.36) and weight gain of ≥10 kg plus non-obesity (OR 1.31, 95% CI 1.21 to 1.42) significantly increased the OR for CKD when compared with weight gain <10 kg plus non-obesity in men. In women, weight gain ≥10 kg plus obesity (OR 2.04, 95% CI 1.84 to 2.25) and weight gain ≥10 kg plus non-obesity (OR 1.53, 95% CI 1.36 to 1.72) significantly increased the OR for CKD compared with weight gain <10 kg plus non-obesity. These results persisted even after adjustment for age, lifestyle factors, hypertension, dyslipidaemia and diabetes.ConclusionsWeight gain ≥10 kg after 20 years of age was significantly associated with CKD in both obese and non-obese subjects. Moreover, the influence of weight gain ≥10 kg plus obesity on CKD was greater than that of weight gain ≥10 kg plus non-obesity on CKD. The present study results suggest that it is important to consider weight gain after maturity in both obese and non-obese subjects to prevent CKD among Japanese middle-aged adults.


Author(s):  
Thea Kirana ◽  
Heriandi Sutadi ◽  
Sarworini B Budiardjo

 Objective: The objective of this study is to analyze the differences in dental calculus indices and calcium and phosphate levels in children with chronic kidney disease undergoing hemodialysis (HD) and peritoneal dialysis (PD) therapy.Methods: In this cross-sectional study, 15 children undergoing HD therapy and 15 undergoing PD therapy were subjected to intraoral examination for dental calculus indices. Whole unstimulated saliva samples of all subjects were collected and subjected to calcium and phosphate analysis. Statistical analyses were conducted using the Mann–Whitney and independent t-tests.Results: The dental calculus indices were significantly lower and salivary calcium level was significantly higher in the PD group than those in the HD group (p<0.05). The salivary phosphate level was lower in the PD group (p≥0.05) but without significance.Conclusion: The PD group had lower dental calculus indices and higher salivary calcium level. The higher salivary phosphate levels in the HD group may have contribute to the higher dental calculus indices, probably because phosphate plays an important role in dental calculus formation.


Author(s):  
Lam Do Ai Nguyen ◽  
Thao Thi Thu Nguyen ◽  
Thuy Anh Vu Pham

<div><p class="AbstractTitle"><strong>Objectives:</strong> To compare periodontal status of chronic kidney disease patients with those in non-chronic kidney disease patients and to explore the relationship between periodontitis and chronic kidney disease in a group of Vietnamese.</p></div><p class="AbstractContent"><strong>Methods:</strong> A cross sectional study was conducted on 240 adults including 120 chronic kidney disease patients (group 1) and 120non-chronic kidney disease patients (group 2). The socio-demographic characteristic, dental and smoking habits were investigated by the questionnaire. Periodontal status (PPD, CAL, BOP) were examined. The periodontal status was compared between 2 groups. Multiple logistic regression analysis was performed to examine the relationship between chronic kidney disease and periodontitis after adjusting related factors.</p><p class="AbstractContent"><strong>Results</strong>: The clinically periodontal parameters in group 1 were all higher compared to those in group 2 (p&lt;0.001). The OR for periodontitis in patients who with age more than 60 years or brushed their teeth less than 2 times per day or had no scaling or in current smokers or with chronic kidney disease were 1.93; 4.27; 7.95; 4.21; 2.94 compared to counterparts, respectively (p&lt;0.05).</p><p class="AbstractContent"><strong>Conclusion:</strong> The periodontal status of chronic kidney disease patients was found worse than those in non-chronic kidney disease patients. The chronic kidney disease was significantly related to periodontitis.</p>


Author(s):  
Marcelo R. Bacci ◽  
Lívia S.S. Cabral ◽  
Glaucia L. da Veiga ◽  
Beatriz da C.A. Alves ◽  
Neif Murad ◽  
...  

Introduction: Hemodialysis stands out as an eligible treatment for patients with chronic kidney disease. The subsequent inflammatory process resulting from this disease and hemodialysis per se is exacerbated in this therapy. Selenium (Se) is an essential trace element that can participate in the inhibition of pro-oxidant and pro-inflammatory processes and could be considered a measurement that indicates the progression of chronic kidney disease and inflammation. Objective: The present study investigated selenemia in hemodialysis patients of the ABC region of São Paulo and aimed to establish the correlation between an inflammatory marker and selenemia in this conditions disease. Methods: This is an observational cross-sectional study of the Faculdade de Medicina do ABC in patients submitted to hemodialysis three times a week for at least six months. The eligible group composed of 21 patients, who filled out forms and underwent biochemical tests (colorimetric enzyme methods, flow cytometer, turbidimetric method and mass spectrometry). Results: The study population showed, women (70%), men (30%) with a mean age of 47 ± 17 years, Caucasians (36%) and non-Caucasian (64%), hypertensive (68%), smokers (53%) and non-smokers (64%). There was a hegemonic prevalence of systolic arterial hypertension (SAH) 68.1% in relation to diabetes mellitus (DM) (50%). Pre and post hemodialysis (HD) selenemia showed statistical significance, which did not occur with Creactive protein. There was a predominance of females in our sample; the pre- and post- HD selenemia were within the normal range of the reference values; there was a statistically significant correlation between pre and post-HD selenemia; there was no correlation with statistical significance between values of pre and post-HD C-reactive protein. Conclusion: Our data showed that there was no direct relationship between pre- and post- HD inflammation and pre- and post-HD selenemia.


2019 ◽  
Vol 7 (2) ◽  
pp. 91
Author(s):  
Rismia Agustina ◽  
Eka Setiawati ◽  
Ghina Pangestika ◽  
Nor Hayatunnisa Hayatunnisa ◽  
Rosina Apriani ◽  
...  

Introduction: Some of the main nursing problems that arise in patients with chronic kidney failure undergoing hemodialysis are problems with excess fluid volume.The aim of this study was to describe increased fluid intake in patients with chronic kidney disease undergoing hemodialysis at Ulin General Hospital of Banjarmasin.Methods: This was a descriptive cross sectional study. 80 respondents were taken using consecutive sampling. The instruments used in this study were questionnaire of demographic, knowledge, attitude, family support, involvement of health workers and Inter-Dialytic Weight Gain (IDWG) calculation sheets.Results: The results showed that the majority of respondents were women (53.8%), the education of respondents was high school (28.8%), the average age of respondents was 48.19 years old, most respondents had been undergoing hemodialysis for less than 12 months (57.5%), the frequency of hemodialysis was 2 times each week (93.8%), the level of knowledge was good (42.5%) and moderate (42.5%), the family support was good (86.3%), the attitude was positive (55%), the involvement of health workers was good (60%), and the majority of respondents had moderate IDWG criteria (47.5%).Conclusion: Almost half of patients with chronic kidney disease who were undergoing hemodialysis at Ulin General Hospital of Banjarmasin had moderate IDWG. Further study is needed to investigate related factors of excessive fluid intake in patients undergoing hemodialysis.


2021 ◽  
Author(s):  
Yuko AGO SHIRAISHI ◽  
Yukiko ISHIKAWA ◽  
Joji ISHIKAWA ◽  
Masami MATSUMURA ◽  
Shizukiyo ISHIKAWA

Abstract Background Strategies to prevent the development and progression of chronic kidney disease (CKD) are now an important theme in clinical practice due to increased life expectancy. The present study investigated the prevalence of CKD as well as lipid profiles affecting CKD. Methods In total, 5,169 subjects were eligible for a cross-sectional analysis of baseline data from the Jichi Medical School Cohort Study. We examined CKD subjects with an estimated glomerular filtration rate (eGFR) of 59 (mL/min/1.73m2) or lower and independent factors associated with reductions in eGFR. Results The prevalence of CKD was 17.7%. Age, systolic blood pressure, and hyperlipidemia were defined as related factors for CKD. The lowest, second, third, and highest quartile ranges of total cholesterol (TC) and triglycerides (TG) were 0-166, 167–188, 189–212, and 213 mg/dL or higher and 0–71, 72–100, 101–148, and 149 mg/dL or higher, respectively. The odds ratio (OR) of Q2 to Q4 of TC relative to that of Q1 for CKD increased linearly [OR (95%CI): Q2, 1.3 (1.0-1.7); Q3, 1.38 (1.1–1.8); Q4, 1.5 (1.4–2.4)]. The ORs of Q2 and Q3 of TG for CKD did not increase, whereas that of Q4 did [OR (95% CI): Q2, 0.95 (0.7–1.2); Q3, 0.98 (0.8–1.2); Q4, 1.21 (1.0-1.5)]. Conclusion TC and TG elevations were both independently associated with CKD. The relationship with CKD became stronger as TC increased, and TG was considered to have a threshold of 149 mg/dL. Prospective studies are expected in the future.


2020 ◽  
Vol 6 (1) ◽  
pp. 19
Author(s):  
Yuli Hermansyah ◽  
Firda Novidyawati ◽  
Ayu Munawaroh Azis

Stage V Chronic Kidney Disease (CKD) is one of the most common medical case in the world. Stage V CKD defined as a condition where the renal function decrease progressively, marked by the GFR  <15/ml/minute/1,73 m2, with or without kidney damage history for three months. Patients diagnosed with Stage V CKD often needs kidney replacement therapy, one of which is hemodialysis. The cost needed for hemodialysis was considered as too expensive, forcing lots of medical staff in most countries using the method known as re-use hemodialyzer. Re-use hemodialyzer is a term for using the same hemodialyzer (or hemodialysis machine) for the same patient but on a different therapy session. The main purpose for this research is to investigate the sodium level in patients with Stage V CKD whose using new and re-use hemodialyzer in Hemodialysis Installation of RSD dr. Soebandi Jember. Analytic Observational Study is used for this research combined with Cross Sectional Study in December 2018. Total of 19 samples chosen with inclusion and exclusion criteria. Collected data is analyzed using paired t-test. The conclusion that can be obtained from this research is that there is no significant difference between sodium level in patients with Stage V CKD whose using new and re-use hemodialyzer (p=0,904). The effectivity and quality of the hemodialyzer is thought to be the main factor for this result. Keywords: Chronic Kidney Disease, sodium, re-use hemodialyzer


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