scholarly journals Periodontal Status in Chronic Kidney Disease Patients

Author(s):  
Lam Do Ai Nguyen ◽  
Thao Thi Thu Nguyen ◽  
Thuy Anh Vu Pham

<div><p class="AbstractTitle"><strong>Objectives:</strong> To compare periodontal status of chronic kidney disease patients with those in non-chronic kidney disease patients and to explore the relationship between periodontitis and chronic kidney disease in a group of Vietnamese.</p></div><p class="AbstractContent"><strong>Methods:</strong> A cross sectional study was conducted on 240 adults including 120 chronic kidney disease patients (group 1) and 120non-chronic kidney disease patients (group 2). The socio-demographic characteristic, dental and smoking habits were investigated by the questionnaire. Periodontal status (PPD, CAL, BOP) were examined. The periodontal status was compared between 2 groups. Multiple logistic regression analysis was performed to examine the relationship between chronic kidney disease and periodontitis after adjusting related factors.</p><p class="AbstractContent"><strong>Results</strong>: The clinically periodontal parameters in group 1 were all higher compared to those in group 2 (p&lt;0.001). The OR for periodontitis in patients who with age more than 60 years or brushed their teeth less than 2 times per day or had no scaling or in current smokers or with chronic kidney disease were 1.93; 4.27; 7.95; 4.21; 2.94 compared to counterparts, respectively (p&lt;0.05).</p><p class="AbstractContent"><strong>Conclusion:</strong> The periodontal status of chronic kidney disease patients was found worse than those in non-chronic kidney disease patients. The chronic kidney disease was significantly related to periodontitis.</p>

2021 ◽  
Author(s):  
Yuko AGO SHIRAISHI ◽  
Yukiko ISHIKAWA ◽  
Joji ISHIKAWA ◽  
Masami MATSUMURA ◽  
Shizukiyo ISHIKAWA

Abstract Background Strategies to prevent the development and progression of chronic kidney disease (CKD) are now an important theme in clinical practice due to increased life expectancy. The present study investigated the prevalence of CKD as well as lipid profiles affecting CKD. Methods In total, 5,169 subjects were eligible for a cross-sectional analysis of baseline data from the Jichi Medical School Cohort Study. We examined CKD subjects with an estimated glomerular filtration rate (eGFR) of 59 (mL/min/1.73m2) or lower and independent factors associated with reductions in eGFR. Results The prevalence of CKD was 17.7%. Age, systolic blood pressure, and hyperlipidemia were defined as related factors for CKD. The lowest, second, third, and highest quartile ranges of total cholesterol (TC) and triglycerides (TG) were 0-166, 167–188, 189–212, and 213 mg/dL or higher and 0–71, 72–100, 101–148, and 149 mg/dL or higher, respectively. The odds ratio (OR) of Q2 to Q4 of TC relative to that of Q1 for CKD increased linearly [OR (95%CI): Q2, 1.3 (1.0-1.7); Q3, 1.38 (1.1–1.8); Q4, 1.5 (1.4–2.4)]. The ORs of Q2 and Q3 of TG for CKD did not increase, whereas that of Q4 did [OR (95% CI): Q2, 0.95 (0.7–1.2); Q3, 0.98 (0.8–1.2); Q4, 1.21 (1.0-1.5)]. Conclusion TC and TG elevations were both independently associated with CKD. The relationship with CKD became stronger as TC increased, and TG was considered to have a threshold of 149 mg/dL. Prospective studies are expected in the future.


2021 ◽  
Author(s):  
Yuko AGO SHIRAISHI ◽  
Yukiko ISHIKAWA ◽  
Joji ISHIKAWA ◽  
Masami MATSUMURA ◽  
Shizukiyo ISHIKAWA

Abstract Background: Strategies to prevent the development and progression of chronic kidney disease (CKD) are important in clinical practice due to increased life expectancy. The present study investigated the prevalence of CKD as well as lipid profiles affecting CKD, especially triglyceride (TG) levels.Methods: In total, 5,169 subjects were eligible for a cross-sectional analysis of baseline data from the Jichi Medical School Cohort Study. We examined CKD subjects with an estimated glomerular filtration rate (eGFR) of 59 mL/min/1.73m2 or lower and independent factors associated with reductions in eGFR.Results: The prevalence of CKD was 17.7%. Age, systolic blood pressure, and hyperlipidemia were defined as related factors for CKD. The lowest, second, third, and highest quartile ranges of total cholesterol (TC) and TG were 0-166, 167-188, 189-212, and 213 mg/dL or higher and 0-71, 72-100, 101-148, and 149 mg/dL or higher, respectively. The odds ratio (OR) of Q2 to Q4 of TC relative to that of Q1 for CKD increased linearly (OR [95%CI]: Q2, 1.3 [1.0-1.7]; Q3, 1.38 [1.1-1.8]; Q4, 1.5 [1.4-2.4]). The ORs of Q2 and Q3 of TG for CKD did not increase, whereas that of Q4 did (OR [95% CI]: Q2, 0.95 [0.7-1.2]; Q3, 0.98 [0.8-1.2]; Q4, 1.21 [1.0-1.5]). Conclusion: Increases in TC and TG levels were both independently associated with CKD. The relationship with CKD became stronger as TC increased, and the TG had threshold was 149 mg/dL.


2019 ◽  
Vol 15 (2) ◽  
pp. 77
Author(s):  
Isnur Hatta ◽  
Khairunnisa Amalia Pratami ◽  
Maharani Laillyza Apriasari

Abstract: Chronic kidney disease (CKD) is a world health problem where the incidence continues to increase, has a poor prognosis and high-level financing. Clinical manifestations of the oral cavity can occur in CKD patients with hemodialysis therapy due to a decrease in the immune system. To analyze the descriptively the clinical manifestations of oral cavity in CKD patients with hemodialysis therapy at RSUD Ulin Banjarmasin South Kalimantan, period January-March 2019. This is a descriptive analysis with a cross sectional study design, based on history and clinical examination of the oral cavity. Data was entered and analyzed using chi square test. Sampling by purposive sampling. there is a relationship between uremic odor and duration of hemodialysis (p = 0.017). There was a relationship between xerostomia and gender (p = 0.035) and there was a relationship between xerostomia and the duration of hemodialysis (p = 0.007). There is a relationship between gingival swelling and age (p = 0.010) and there is a relationship between gingival swelling and diabetes mellitus (p = 0,000). Manifestations found in the oral cavity of CKD patients with hemodialysis therapy are uremic odor, mouthache, xerostomia, mucosal lesions, candidiasis, and gingival swelling. There is a relationship between sex with xerostomia, the relationship between age with gingival swelling, the relationship between the duration of hemodialysis with uremic odor and xerostomia, the association between DM with gingival swelling. Keywords: Chronic Kidney Disease, Clinical Manifestations, Hemodialysis, Oral Cavity


2021 ◽  
Author(s):  
Rajeev Kumar ◽  
Pratip Jana ◽  
Indu Priyadarshini ◽  
SMITA ROY ◽  
Pritha Dutta ◽  
...  

ABSTRACT INTRODUCTION The SARS-CoV-2 pandemic has emerged as perhaps the most challenging global health problem of this century. The concomitant presence of co morbidities like chronic kidney disease (CKD), diabetes, chronic heart disease etc. makes the task of patient management difficult. AIMS AND OBJECTIVES To assess the patterns of liver test abnormalities in patients of COVID 19 infection with and without CKD and evaluate the probable outcomes. MATERIALs and METHODS A cross-sectional retrospective observational study done on 600 patient samples (Group 1 COVID-19 without CKD, Group 2 COVID-19 with CKD and Group 3 non COVID-19 with CKD) which were processed for Liver function test (AST, ALT and ALP) and Renal function test (Urea and Creatinine) in the Department of Biochemistry, Dr. RML Hospital New Delhi. RESULTS AST and ALT levels were significantly higher (P < 0.05) in all COVID 19 positive patients group 1 mean and 2 SD, (63.63 and 42.89 U/L & 50.25 and 46.53 U/L respectively) and group 2 (90.59 and 62.51 U/L & 72.09 and 67.24 U/L respectively) as compared to Group 3 (25.24 and 7.47 U/L & 24.93 and 11.44 U/L respectively) and also a statistically significant elevation is seen in these two parameters (AST & ALT) in Group 2 as compared to Group 1 (P < 0.05). There was a negative significant correlation between eGFR and AST/ALT levels in Group 1 (p < 0.05). In Group 2, a weak positive correlation was seen with ALT (p < 0.01). No significant correlation existed between eGFR and ALP in groups 1 and 2. In Group 3, eGFR showed strong correlations with AST and ALT levels (p < 0.01) and reduction in kidney function correlated well with increase in serum ALP levels, (p < 0.01). CONCLUSIONS This study most comprehensively describes that SARS-CoV-2 positive CKD patients show more elevations in serum aminotransferase levels as compared to their non-CKD counterparts, in contrast to non-COVID-19 CKD cases. Serum ALT values in SARS-CoV-2 patients show significant correlation with calculated eGFR values. Elevated ALP values in CKD patients may be used as an indicator of declining kidney function. However, more studies in this direction are needed.


2019 ◽  
Vol 7 (2) ◽  
pp. 91
Author(s):  
Rismia Agustina ◽  
Eka Setiawati ◽  
Ghina Pangestika ◽  
Nor Hayatunnisa Hayatunnisa ◽  
Rosina Apriani ◽  
...  

Introduction: Some of the main nursing problems that arise in patients with chronic kidney failure undergoing hemodialysis are problems with excess fluid volume.The aim of this study was to describe increased fluid intake in patients with chronic kidney disease undergoing hemodialysis at Ulin General Hospital of Banjarmasin.Methods: This was a descriptive cross sectional study. 80 respondents were taken using consecutive sampling. The instruments used in this study were questionnaire of demographic, knowledge, attitude, family support, involvement of health workers and Inter-Dialytic Weight Gain (IDWG) calculation sheets.Results: The results showed that the majority of respondents were women (53.8%), the education of respondents was high school (28.8%), the average age of respondents was 48.19 years old, most respondents had been undergoing hemodialysis for less than 12 months (57.5%), the frequency of hemodialysis was 2 times each week (93.8%), the level of knowledge was good (42.5%) and moderate (42.5%), the family support was good (86.3%), the attitude was positive (55%), the involvement of health workers was good (60%), and the majority of respondents had moderate IDWG criteria (47.5%).Conclusion: Almost half of patients with chronic kidney disease who were undergoing hemodialysis at Ulin General Hospital of Banjarmasin had moderate IDWG. Further study is needed to investigate related factors of excessive fluid intake in patients undergoing hemodialysis.


2021 ◽  
pp. 089686082199820
Author(s):  
Saleem Abdulkarim ◽  
Jasmit Shah ◽  
Ahmed Twahir ◽  
Ahmed P Sokwala

Introduction: The burden of chronic kidney disease (CKD) is increasing in Kenya and is a significant cause of morbidity and mortality. While definitive treatment is renal transplantation, many patients require kidney replacement therapy with haemodialysis (HD) or peritoneal dialysis (PD). The predominant modality utilized in Kenya is currently HD. There is a need to explore why PD remains underutilized and whether patient factors may be contributory to barriers that limit the uptake of PD. Methods: This was a descriptive cross-sectional study where patients with advanced CKD were assessed by a multidisciplinary team for PD eligibility using a standardized tool. Contraindications and barriers to the modality were recorded as was the presence or absence of support for the provision of PD. Demographic and clinical data were recorded using a standardized questionnaire. The impact of support on PD eligibility was determined. Results: We found that 68.9% patients were eligible for PD. Surgery-related abdominal scarring was the most common contraindication. Barriers to PD were identified in 45.9% and physical barriers were more common than cognitive barriers. Presence of support was associated with a significant increase in PD eligibility ( p < 0.001). Conclusion: The rate of eligibility for PD in this study was similar to that found in other populations. Surgical-related factors were the most commonly identified contraindication. Physical and cognitive barriers were commonly identified and may be overcome by the presence of support for PD.


Children ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 6
Author(s):  
Jie Xu ◽  
Lingxiao Tong ◽  
Jianhua Mao

Background: Hyperuricemia is increasingly recognized as a risk factor for chronic kidney disease (CKD) just in adults. The purpose of this study was to investigate the clinical characteristics of hyperuricemia and its associated factors in Chinese children with CKD at a single center. Methods: A cross-sectional study of 170 CKD children collected from the Department of Nephrology, The Zhejiang University Children’s Hospital was conducted. The clinical data, including anthropometric data, blood pressure measurements, and biochemical parameters, were recorded and analyzed retrospectively. The factors associated with hyperuricemia in CKD children were evaluated by Pearson and Spearman correlation analysis and multiple logistic regression analysis. Results: The mean age was 9.79 ± 4.10 years, and 72 (42.35%) were girls. Higher blood urea nitrogen (BUN), serum creatinine, cystatin C, D-dimer, lower hemoglobin, albumin, and estimated glomerular filtration rate (eGFR) were significantly associated with higher serum uric acid (SUA). In multiple logistic regression analysis, anemia and higher BUN were both positively associated factors, whereas eGFR ≥ 90 mL/min/1.73 m2 was a negatively associated factor for subjects with SUA ≥ 390 µmol/L (6.5 mg/dL). Conclusions: SUA was significantly associated with kidney risk factors in CKD children. Monitoring and controlling SUA, Hb, BUN, and Scr levels in CKD children may help to prevent the progression of CKD.


2016 ◽  
Vol 6 (2) ◽  
pp. 159-168 ◽  
Author(s):  
Daisuke Hasegawa ◽  
Akihito Tanaka ◽  
Daijo Inaguma ◽  
Eri Ito ◽  
Naoki Kamegai ◽  
...  

Background: Recently, sleep apnea syndrome (SAS) has been associated with hypertension, cardiovascular disease and death. Patients with chronic kidney disease (CKD) have higher rates of SAS, atherosclerotic complications and death than do patients without CKD. Although the relationship between SAS and atherosclerosis is well known, few papers have described this relationship in humans, especially in CKD patients. Patients and Methods: This was a cross-sectional study of 110 clinically stable, non-dialysis patients with CKD who attended a CKD educational program from April 2014 to September 2015. The diagnosis of SAS and its severity were assessed using a type 3 portable monitor. Other atherosclerosis-related data were obtained from the patients' medical records in order to determine the factors associated with the severity of SAS. Results: 95 men and 15 women with a mean age of 71.4 ± 9.9 years were included in the study. The patients' mean body mass index was 24.0 ± 3.9, their mean blood pressure 134.3 ± 21.2/73.6 ± 13.4 mm Hg and their mean estimated glomerular filtration rate 19.8 ± 9.5 ml/min/1.7 m2. Adjusted plaque score was a significant predictor of severe SAS (odds ratio = 1.13, p = 0.0182). Mixed plaque was significantly associated with severe SAS (correlation ratio = 0.48, p < 0.0001). Conclusions: Many patients with CKD also have SAS. Our findings demonstrate the relationship between plaque score and the severity of SAS.


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